iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	TRANSFAC	miRNAMap	RAID2
Post-translational Modifications (PTMs)
CPLM
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	8.40e-14	51.6	338	372

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 3    tdsvtclaf....sdtllvsGsdDgtikvWDlrtgv 34
           ++sv +++f    + +l+v G++ g+i +WD r+++
   Q: 338  QSSVMSVCFarfhP-NLVVGGTYSGQIVLWDNRSHR 372
           57899999999754.9999999*********98875 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MSDKSDLKAE LERKKQRLAQ IREEKKRKEE ERKKKEADMQ QKKEPVPDDS DLDRKRRETE 60
ALLQSIGISP EPPLVQPLHF LTWDTCYFHY LVPTPMSPSS KSVSTPSEAG SQDDLGPLTR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAAGCTCAGG AGAGAGGAAG TGATCGCTCC GGGAGGAGCG CTAGCCTAGC CGCGCAGCGT 60
GAGACAGCAC ATCCTGCTGG CGCGGGCCCG CTGCTCCCCG TCCTCCCGCG CCTCCTCCAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR025956--DYNC1I1/DYNC1I2
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50294--WD_REPEATS_REGION

Pfam

PF11540--Dynein_IC2
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005868--C:cytoplasmic dynein complex
GO:0036464--C:cytoplasmic ribonucleoprotein granule
GO:0000776--C:kinetochore
GO:0005634--C:nucleus
GO:0055037--C:recycling endosome
GO:0000922--C:spindle pole
GO:0047496--P:vesicle transport along microtubule

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001500	Ailuropoda melanoleuca	97.83	0.00e+00	1226.00
IUUC-Aca-004659	Anolis carolinensis	91.32	0.00e+00	1117.00
IUUC-Ame-010879	Astyanax mexicanus	81.17	0.00e+00	1035.00
IUUC-Bgr-011987	Blumeria graminis	39.91	2.00e-100	360.00
IUUC-Bta-013557	Bos taurus	91.94	0.00e+00	1123.00
IUUC-Cja-018913	Callithrix jacchus	98.14	0.00e+00	1228.00
IUUC-Cfa-020794	Canis familiaris	95.35	0.00e+00	1179.00
IUUC-Cpo-021891	Cavia porcellus	97.69	0.00e+00	964.00
IUUC-Csa-023506	Chlorocebus sabaeus	95.19	0.00e+00	1175.00
IUUC-Cho-025102	Choloepus hoffmanni	84.03	0.00e+00	1004.00
IUUC-Csv-025876	Ciona savignyi	48.15	3.00e-175	608.00
IUUC-Cgl-026617	Colletotrichum gloeosporioides	39.74	9.00e-88	318.00
IUUC-Dre-028093	Danio rerio	76.74	0.00e+00	955.00
IUUC-Dno-029846	Dasypus novemcinctus	97.60	0.00e+00	946.00
IUUC-Dor-030613	Dipodomys ordii	97.52	0.00e+00	1218.00
IUUC-Ete-032322	Echinops telfairi	83.41	0.00e+00	1002.00
IUUC-Eca-033324	Equus caballus	97.98	0.00e+00	1227.00
IUUC-Fca-036050	Felis catus	91.76	0.00e+00	1087.00
IUUC-Fal-037664	Ficedula albicollis	92.71	0.00e+00	1153.00
IUUC-Gmo-038624	Gadus morhua	73.41	0.00e+00	863.00
IUUC-Ggr-039785	Gaeumannomyces graminis	38.48	3.00e-82	300.00
IUUC-Gga-040886	Gallus gallus	93.02	0.00e+00	1155.00
IUUC-Gac-042215	Gasterosteus aculeatus	75.66	0.00e+00	899.00
IUUC-Ggo-045363	Gorilla gorilla	97.98	0.00e+00	1226.00
IUUC-Hsa-046861	Homo sapiens	97.98	0.00e+00	1226.00
IUUC-Itr-048603	Ictidomys tridecemlineatus	98.70	0.00e+00	955.00
IUUC-Kpa-049295	Komagataella pastoris	25.35	2.00e-29	123.00
IUUC-Loc-052873	Lepisosteus oculatus	87.02	0.00e+00	1082.00
IUUC-Laf-053494	Loxodonta africana	97.67	0.00e+00	1225.00
IUUC-Mcc-055731	Macaca mulatta	97.98	0.00e+00	1226.00
IUUC-Mga-059796	Meleagris gallopavo	93.42	0.00e+00	945.00
IUUC-Mmr-060828	Microcebus murinus	97.98	0.00e+00	1227.00
IUUC-Mmu-063862	Mus musculus	98.91	0.00e+00	1238.00
IUUC-Mpu-066835	Mustela putorius furo	95.35	0.00e+00	1181.00
IUUC-Mlu-067993	Myotis lucifugus	96.92	0.00e+00	1215.00
IUUC-Nle-069711	Nomascus leucogenys	98.14	0.00e+00	1229.00
IUUC-Opr-070509	Ochotona princeps	96.55	0.00e+00	1167.00
IUUC-Ont-072346	Oreochromis niloticus	78.86	0.00e+00	961.00
IUUC-Ocu-074398	Oryctolagus cuniculus	94.88	0.00e+00	1173.00
IUUC-Ola-087168	Oryzias latipes	76.05	0.00e+00	936.00
IUUC-Oga-088138	Otolemur garnettii	97.40	0.00e+00	935.00
IUUC-Oar-090454	Ovis aries	94.42	0.00e+00	1169.00
IUUC-Ptr-090850	Pan troglodytes	97.98	0.00e+00	1226.00
IUUC-Pan-092449	Papio anubis	95.19	0.00e+00	1175.00
IUUC-Psi-093490	Pelodiscus sinensis	92.56	0.00e+00	1137.00
IUUC-Pab-098252	Pongo abelii	97.98	0.00e+00	1227.00
IUUC-Pca-100827	Procavia capensis	98.03	0.00e+00	640.00
IUUC-Pva-102223	Pteropus vampyrus	92.56	0.00e+00	1139.00
IUUC-Sja-107798	Schizosaccharomyces japonicus	24.68	2.00e-29	124.00
IUUC-Ssc-115238	Sus scrofa	97.59	0.00e+00	1078.00
IUUC-Tgu-117310	Taeniopygia guttata	89.29	0.00e+00	966.00
IUUC-Tsy-119423	Tarsius syrichta	83.57	0.00e+00	959.00
IUUC-Ttr-129188	Tursiops truncatus	98.14	0.00e+00	1229.00
IUUC-Xtr-132370	Xenopus tropicalis	88.14	0.00e+00	961.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence