iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Gac-042082

UUCD1 version

UUC-GaA-01253

Ensembl Protein ID

ENSGACP00000022777.1

UniProt Accession

G3PYT7; G3PYT7_GASAC

Protein Name

Uncharacterized protein

Gene Name

usp38; USP38

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGACG00000017248.1	ENSGACT00000022820.1	ENSGACP00000022777.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.00e-76	257.8	445	924

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           tGl NlgNtC++NS++Q+L++ +++r+ +l+    +ln +n      +l+k+lq lf+ l ++++ a++p+++l+a +   + f+  +q
   Q: 445  TGLVNLGNTCFLNSIIQTLFMATDFRRHVLS---LHLNGSN------PLMKKLQLLFAFLAHTQRAAYAPKNFLEASR--PPWFNVGSQ 522
           7******************************...7777765......7***************************998..777****** PP
   S: 90   qDaqEflaflldqleeelkk................eknkpkeeeeeedkselsde..............aeekkkkknkslisdlFqg 148
           qD++E+l+flld+l+ee k                  ++k+ +                            e k+++ +++li+++F+g
   Q: 523  QDCSEYLRFLLDRLHEEEKTlqvlesvkpkvappvnTSSKDPQ------------AqnppdncedsslspDEMKPENDGRTLIERTFGG 599
           ******************8898887666655554442222222............2334444555566666678888888********* PP
   S: 149  qlksqikclecdnvssreepfldlslpvpgkeetkke...............................................slqdc 190
           +l + i+c +c+ +s++eepf+dlsl++  + ++  +                                               s+ d+
   Q: 600  KLITGIRCMQCNCISEKEEPFTDLSLAFCPSASQGSPqpegpseepkvlcqgsvnggsetpeaasakapasnvqfvpvtnepalSVPDL 688
           ***************************9977755444799************************************************* PP
   S: 191  LesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdls......pfcts...... 267
            + f ++e l++en+y+cekc ++q+ae+++k+ + Pe+Lil L Rfs++ + ++r+ki ++v++p  + l       p   +      
   Q: 689  VNYFLAPEILDEENAYFCEKCSSLQRAERTMKVVSAPEYLILTLLRFSYDAKCHVRRKILDNVTIPPLMRLPvhaplmP---Tqcssct 774
           *****************************************************************96655553343331...1455677 PP
   S: 268  ........................peekqkekkkYeLiavvvHsG.slssGHYvayvkn.............................. 301
                                   +ee++++++ Y L++vv+HsG s++sGHY++y  n                              
   Q: 775  ssplqvdspessenlakklkpsqkDEEEEEKSVPYVLSSVVMHSGmSSESGHYYSYGHNingadgaqhpanhfalredlenghpdggls 863
           78898888888888888888877744444459********************************************************* PP
   S: 302  ....................ekgkWllfdDskVtevkeeevleetg....staYvlfYkrr 338
                               e ++Wllf+Ds+Vt ++ ++v++ t+    +taYvl+Y+++
   Q: 864  tcsalsippergvalpnsgqEARDWLLFNDSRVTFTSFQSVQNITNrfpkDTAYVLMYRKQ 924
           ********9999999976644555*******************999************986 PP

Organism

Gasterosteus aculeatus

Protein Sequence
(Fasta)

MDKILEGLVS SDHSVPVKRA IVKKVVEAAE KEVTEEQCQA LFTLTTRLIL LGEDAFQKQI 60
GFQVLEAYAR YHRPDFERFF SKDFVLGLLQ QGYGQLDRKD PATIDYIHCC LRLLISCPSV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGACAAGA TTTTGGAGGG CCTTGTGAGC TCGGATCACT CTGTTCCGGT GAAGCGGGCC 60
ATTGTGAAGA AGGTAGTGGA AGCAGCGGAG AAAGAAGTGA CGGAGGAGCA GTGTCAGGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR001394--Peptidase_C19_UCH
IPR033840--USP38
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002174	Ailuropoda melanoleuca	62.90	0.00e+00	1162.00
IUUC-Apl-003435	Anas platyrhynchos	60.92	0.00e+00	975.00
IUUC-Aca-004556	Anolis carolinensis	58.55	0.00e+00	1030.00
IUUC-Ame-010616	Astyanax mexicanus	70.58	0.00e+00	1372.00
IUUC-Bta-013544	Bos taurus	62.84	0.00e+00	1164.00
IUUC-Cja-018745	Callithrix jacchus	62.58	0.00e+00	1186.00
IUUC-Cfa-020434	Canis familiaris	61.65	0.00e+00	1137.00
IUUC-Cpo-021666	Cavia porcellus	62.73	0.00e+00	1150.00
IUUC-Csa-023965	Chlorocebus sabaeus	63.56	0.00e+00	1227.00
IUUC-Cho-024809	Choloepus hoffmanni	54.35	0.00e+00	728.00
IUUC-Cin-025604	Ciona intestinalis	30.34	2.00e-40	159.00
IUUC-Csv-026333	Ciona savignyi	38.50	6.00e-30	124.00
IUUC-Dre-028338	Danio rerio	70.42	0.00e+00	1394.00
IUUC-Dno-029372	Dasypus novemcinctus	63.52	0.00e+00	1194.00
IUUC-Dor-030752	Dipodomys ordii	58.88	0.00e+00	732.00
IUUC-Dme-031871	Drosophila melanogaster	26.12	5.00e-61	229.00
IUUC-Ete-032588	Echinops telfairi	54.14	0.00e+00	698.00
IUUC-Eca-034416	Equus caballus	63.24	0.00e+00	1213.00
IUUC-Eeu-035132	Erinaceus europaeus	49.62	0.00e+00	846.00
IUUC-Fca-036137	Felis catus	63.68	0.00e+00	1215.00
IUUC-Fal-037297	Ficedula albicollis	60.74	0.00e+00	1115.00
IUUC-Gmo-038727	Gadus morhua	80.92	0.00e+00	1211.00
IUUC-Gga-041091	Gallus gallus	60.44	0.00e+00	1104.00
IUUC-Ggo-045376	Gorilla gorilla	60.26	0.00e+00	1119.00
IUUC-Hsa-046444	Homo sapiens	63.80	0.00e+00	1234.00
IUUC-Itr-047976	Ictidomys tridecemlineatus	63.55	0.00e+00	1211.00
IUUC-Lch-050500	Latimeria chalumnae	62.76	0.00e+00	1211.00
IUUC-Loc-052625	Lepisosteus oculatus	70.78	0.00e+00	1394.00
IUUC-Laf-053689	Loxodonta africana	63.19	0.00e+00	1196.00
IUUC-Mcc-055286	Macaca mulatta	63.52	0.00e+00	1224.00
IUUC-Meu-056906	Macropus eugenii	48.81	7.00e-175	607.00
IUUC-Mga-059905	Meleagris gallopavo	60.04	0.00e+00	924.00
IUUC-Mmr-061397	Microcebus murinus	63.82	0.00e+00	1177.00
IUUC-Mdo-062833	Monodelphis domestica	64.53	0.00e+00	1266.00
IUUC-Mmu-063157	Mus musculus	62.23	0.00e+00	1164.00
IUUC-Mpu-066434	Mustela putorius furo	63.57	0.00e+00	1214.00
IUUC-Mlu-068178	Myotis lucifugus	63.22	0.00e+00	1139.00
IUUC-Nle-070153	Nomascus leucogenys	63.52	0.00e+00	1163.00
IUUC-Opr-070454	Ochotona princeps	43.97	3.00e-67	250.00
IUUC-Ont-072330	Oreochromis niloticus	84.43	0.00e+00	1650.00
IUUC-Oan-072709	Ornithorhynchus anatinus	61.36	0.00e+00	917.00
IUUC-Ocu-074832	Oryctolagus cuniculus	63.29	0.00e+00	1172.00
IUUC-Ola-087003	Oryzias latipes	73.04	3.00e-69	254.00
IUUC-Oga-088517	Otolemur garnettii	61.99	0.00e+00	1155.00
IUUC-Oar-089472	Ovis aries	61.34	0.00e+00	1088.00
IUUC-Ptr-090996	Pan troglodytes	63.71	0.00e+00	1233.00
IUUC-Pan-091837	Papio anubis	62.17	0.00e+00	1181.00
IUUC-Psi-093236	Pelodiscus sinensis	60.32	0.00e+00	864.00
IUUC-Pma-094349	Petromyzon marinus	52.62	0.00e+00	951.00
IUUC-Pfo-097193	Poecilia formosa	80.12	0.00e+00	1526.00
IUUC-Pab-098710	Pongo abelii	63.58	0.00e+00	1247.00
IUUC-Pca-100794	Procavia capensis	55.72	0.00e+00	1025.00
IUUC-Pva-102722	Pteropus vampyrus	63.31	0.00e+00	1212.00
IUUC-Rno-105743	Rattus norvegicus	62.70	0.00e+00	1162.00
IUUC-Sha-106563	Sarcophilus harrisii	63.02	0.00e+00	1000.00
IUUC-Sar-113533	Sorex araneus	56.59	0.00e+00	1040.00
IUUC-Ssc-116259	Sus scrofa	78.24	0.00e+00	784.00
IUUC-Tgu-117475	Taeniopygia guttata	59.96	0.00e+00	994.00
IUUC-Tru-118623	Takifugu rubripes	81.37	0.00e+00	1536.00
IUUC-Tsy-119250	Tarsius syrichta	61.58	0.00e+00	884.00
IUUC-Tni-120441	Tetraodon nigroviridis	76.67	0.00e+00	1454.00
IUUC-Tbe-127936	Tupaia belangeri	53.30	0.00e+00	909.00
IUUC-Ttr-128483	Tursiops truncatus	53.27	0.00e+00	828.00
IUUC-Vpa-130303	Vicugna pacos	78.28	0.00e+00	837.00
IUUC-Xtr-132773	Xenopus tropicalis	60.91	0.00e+00	1142.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence