iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cja-019284

UUCD1 version

UUC-CaJ-00049

Ensembl Protein ID

ENSCJAP00000033851.2

UniProt Accession

F6QNB0; F6QNB0_CALJA

Genbank Protein ID

JAB02786.1; JAB16225.1; JAB29940.1; JAB36220.1; JAB47757.1; JAB47758.1; JAB47759.1; JAB47760.1

Protein Name

Suppressor of cytokine signaling 4

Genbank Nucleotide ID

ACFV01047960; GAMS01006911; GAMR01003992; GAMQ01005631; GAMP01004998; GAMP01004997; GAMP01004996; GAMP01004995

Gene Name

SOCS4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCJAG00000018289.2	ENSCJAT00000035761.2	ENSCJAP00000033851.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	8.90e-17	61.7	378	425

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 3    klwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyedyq 53
           +++l+r+ p+SLqh+CR +I++c++++++   d+LP+P+s+k YL++++y+
   Q: 378  STPLIRTFPFSLQHICRTVICNCTTYDGI---DALPIPSSMKLYLKEYHYK 425
           678899***********************...****************985 PP

Organism

Callithrix jacchus

Protein Sequence
(Fasta)

MAENNENISK NVDVRPKTSR SRSADRKDGY VWSGKKLSWS KKSESCSDAE TVNDIEKTEV 60
SLRSQERKHS CSSIELDLDH SCGHRFLGRS LKQKLQDAVG QCFPIKNCSS RHSSGLPSKR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACTGTGA CGGCTGGGAT GGGACCAGAA CGCCGAAGCG GGATTGGGGG TGGCAGAAAG 60
GCATCCGCTT TGTAAGACCT ACACGAGGTG CCGGAGTGGT TGGGCCTCCC CTCCCTACTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR028416--SOCS4
IPR022252--SOCS4/SOCS5_dom
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF12610--SOCS
PF07525--SOCS_box

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005622--C:intracellular
GO:0035556--P:intracellular signal transduction
GO:0007175--P:negative regulation of epidermal growth factor-activated receptor activity
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0016567--P:protein ubiquitination

KEGG

cjc:100386210

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001789	Ailuropoda melanoleuca	93.85	0.00e+00	785.00
IUUC-Apl-003839	Anas platyrhynchos	79.50	0.00e+00	640.00
IUUC-Aca-004840	Anolis carolinensis	79.27	0.00e+00	696.00
IUUC-Ame-010732	Astyanax mexicanus	79.65	1.00e-85	310.00
IUUC-Bta-012503	Bos taurus	92.73	0.00e+00	780.00
IUUC-Bol-016597	Brassica oleracea	31.03	4.00e-02	33.10
IUUC-Cfa-020890	Canis familiaris	93.64	0.00e+00	797.00
IUUC-Cpo-022081	Cavia porcellus	78.12	0.00e+00	674.00
IUUC-Csa-023076	Chlorocebus sabaeus	97.05	0.00e+00	818.00
IUUC-Cho-024700	Choloepus hoffmanni	93.88	0.00e+00	835.00
IUUC-Dno-029961	Dasypus novemcinctus	94.10	0.00e+00	830.00
IUUC-Dor-030273	Dipodomys ordii	92.97	0.00e+00	792.00
IUUC-Ete-032972	Echinops telfairi	91.35	1.00e-167	582.00
IUUC-Eca-034289	Equus caballus	94.33	0.00e+00	793.00
IUUC-Eeu-035208	Erinaceus europaeus	90.21	0.00e+00	747.00
IUUC-Fal-036829	Ficedula albicollis	79.73	0.00e+00	637.00
IUUC-Gga-040725	Gallus gallus	79.04	0.00e+00	667.00
IUUC-Ggo-044886	Gorilla gorilla	97.95	0.00e+00	829.00
IUUC-Hsa-046322	Homo sapiens	97.73	0.00e+00	827.00
IUUC-Itr-048585	Ictidomys tridecemlineatus	93.79	0.00e+00	788.00
IUUC-Lch-049459	Latimeria chalumnae	57.08	5.00e-137	480.00
IUUC-Laf-053484	Loxodonta africana	94.48	0.00e+00	787.00
IUUC-Mcc-054890	Macaca mulatta	96.82	0.00e+00	816.00
IUUC-Meu-056532	Macropus eugenii	84.30	0.00e+00	637.00
IUUC-Mtr-057670	Medicago truncatula	36.67	2.20e+00	26.60
IUUC-Mvi-060418	Microbotryum violaceum	32.10	1.40e-02	33.10
IUUC-Mmr-061714	Microcebus murinus	95.92	0.00e+00	801.00
IUUC-Mmu-063161	Mus musculus	87.02	0.00e+00	739.00
IUUC-Mpu-066499	Mustela putorius furo	94.32	0.00e+00	824.00
IUUC-Mlu-066945	Myotis lucifugus	92.52	0.00e+00	779.00
IUUC-Nle-069976	Nomascus leucogenys	97.73	0.00e+00	825.00
IUUC-Opr-070255	Ochotona princeps	86.36	0.00e+00	745.00
IUUC-Ocu-074764	Oryctolagus cuniculus	92.74	0.00e+00	786.00
IUUC-Oga-088910	Otolemur garnettii	88.46	0.00e+00	774.00
IUUC-Oar-090330	Ovis aries	92.73	0.00e+00	776.00
IUUC-Ptr-090709	Pan troglodytes	97.95	0.00e+00	829.00
IUUC-Pan-092540	Papio anubis	97.05	0.00e+00	818.00
IUUC-Psi-093678	Pelodiscus sinensis	81.59	0.00e+00	722.00
IUUC-Pab-097970	Pongo abelii	96.51	0.00e+00	682.00
IUUC-Pop-098820	Populus trichocarpa	41.18	1.20e-01	31.20
IUUC-Pca-100211	Procavia capensis	82.31	0.00e+00	660.00
IUUC-Rno-106014	Rattus norvegicus	85.19	0.00e+00	731.00
IUUC-Sha-106822	Sarcophilus harrisii	84.28	0.00e+00	717.00
IUUC-Ssc-115821	Sus scrofa	93.42	0.00e+00	785.00
IUUC-Tgu-117117	Taeniopygia guttata	80.18	0.00e+00	640.00
IUUC-Tsy-118979	Tarsius syrichta	97.03	8.00e-128	449.00
IUUC-Tca-121131	Theobroma cacao	30.77	2.00e-03	36.60
IUUC-Vpa-130626	Vicugna pacos	92.97	0.00e+00	790.00
IUUC-Vvi-131327	Vitis vinifera	43.75	9.10e-02	31.60

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence