iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fca-036429

Ensembl Protein ID

ENSFCAP00000003590.3

UniProt Accession

M3W155; M3W155_FELCA

Genbank Protein ID

ENSFCAP00000003590

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02093521

Gene Name

TLE1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000003893.3	ENSFCAT00000003894.3	ENSFCAP00000003590.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.10e-21	76.0	620	658

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gHtd+ +c++  +d t l++G+ D+t++ WDlr+g++l+
   Q: 620  GHTDGASCIDIsNDgTKLWTGGLDNTVRSWDLREGRQLQ 658
           8***********999*********************998 PP

Organism

Felis catus

Protein Sequence
(Fasta)

MFPQSRHPTP HQAAGQPFKF TIPESLDRIK EEFQFLQAQY HSLKLECEKL ASEKTEMQRH 60
YVMYYEMSYG LNIEMHKQTE IAKRLNTICA QVIPFLSQEH QQQVAQAVER AKQVTMAELN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

NNNNNNNNNN NNNNNNNNNN NAGAGGGCCG AGGAAGGGGC TCGGAGGAAG AGTCCAGAGC 60
GGCCGGGCCG GCCGTGCGGG GCGAGTGCGC GCGGGGCGCG GCGCCCGGAT GCGCCCCGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR005617--Groucho/TLE_N
IPR009146--Groucho_enhance
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF03920--TLE_N
PF00400--WD40

PRINTS

PR01850--GROUCHOFAMLY

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0001106--F:RNA polymerase II transcription corepressor activity
GO:2000811--P:negative regulation of anoikis
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0010628--P:positive regulation of gene expression

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Cfa-020611	Canis familiaris	99.65	0.00e+00	1072.00
IUUC-Cin-025767	Ciona intestinalis	57.66	8.00e-169	587.00
IUUC-Dno-029011	Dasypus novemcinctus	99.48	0.00e+00	1074.00
IUUC-Eeu-034666	Erinaceus europaeus	99.31	0.00e+00	1078.00
IUUC-Fal-036696	Ficedula albicollis	90.14	0.00e+00	1174.00
IUUC-Gmo-038805	Gadus morhua	79.87	0.00e+00	1139.00
IUUC-Gga-041113	Gallus gallus	91.11	0.00e+00	1284.00
IUUC-Lch-050437	Latimeria chalumnae	95.82	0.00e+00	1048.00
IUUC-Laf-053862	Loxodonta africana	98.95	0.00e+00	1078.00
IUUC-Mmr-061207	Microcebus murinus	99.48	0.00e+00	1070.00
IUUC-Mdo-062493	Monodelphis domestica	91.75	0.00e+00	1267.00
IUUC-Oga-088629	Otolemur garnettii	99.30	0.00e+00	1074.00
IUUC-Pfo-096239	Poecilia formosa	78.33	0.00e+00	1125.00
IUUC-Pca-100675	Procavia capensis	99.13	0.00e+00	1063.00
IUUC-Pva-102355	Pteropus vampyrus	94.11	0.00e+00	985.00
IUUC-Sha-107419	Sarcophilus harrisii	82.90	0.00e+00	1152.00
IUUC-Sar-113585	Sorex araneus	86.75	0.00e+00	717.00
IUUC-Tsy-119342	Tarsius syrichta	95.12	0.00e+00	985.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence