iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000007427.1	ENSPSIT00000008322.1	ENSPSIP00000008279.1
ENSPSIG00000007427.1	ENSPSIT00000008329.1	ENSPSIP00000008286.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.90e-22	77.9	618	656

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gHtd+ +c++  +d t l++G+ D+t++ WDlr+g++l+
   Q: 618  GHTDGASCIDIsNDgTKLWTGGLDNTVRSWDLREGRQLQ 656
           8***********999*********************998 PP

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

TPHQAAGQPF KFTIPESLDR IKEEFQFLQA QYHSLKLECE KLASEKTEMQ RHYVMYYEMS 60
YGLNIEMHKQ TEIAKRLNTI CAQVIPFLSQ EHQQQVAQAV ERAKQVTMAE LNAIIGVRGL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

NNNNNNNNNN NNNNNNNNNN NNNTTCCACC CCCCCACCCC CCCCCCACAG GACTTGATTT 60
TACAGCAGGG AGCGGTTAGC AACCTACTAG TTTTCCTGGG ATGGTGGTGA CAAGTGTAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR005617--Groucho/TLE_N
IPR009146--Groucho_enhance
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF03920--TLE_N
PF00400--WD40

PRINTS

PR01850--GROUCHOFAMLY

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0001106--F:RNA polymerase II transcription corepressor activity
GO:2000811--P:negative regulation of anoikis
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0010628--P:positive regulation of gene expression

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001746	Ailuropoda melanoleuca	92.66	0.00e+00	1223.00
IUUC-Apl-003594	Anas platyrhynchos	94.87	0.00e+00	1256.00
IUUC-Aca-005053	Anolis carolinensis	96.38	0.00e+00	1283.00
IUUC-Bta-013380	Bos taurus	88.13	0.00e+00	1120.00
IUUC-Cja-019135	Callithrix jacchus	96.51	0.00e+00	1271.00
IUUC-Cfa-020611	Canis familiaris	96.28	0.00e+00	1170.00
IUUC-Cpo-022495	Cavia porcellus	95.87	0.00e+00	1267.00
IUUC-Csa-024056	Chlorocebus sabaeus	96.38	0.00e+00	1288.00
IUUC-Cin-025767	Ciona intestinalis	58.32	8.00e-170	590.00
IUUC-Dno-029011	Dasypus novemcinctus	97.16	0.00e+00	1274.00
IUUC-Ete-032533	Echinops telfairi	84.24	0.00e+00	1156.00
IUUC-Eca-033351	Equus caballus	96.77	0.00e+00	1274.00
IUUC-Eeu-034666	Erinaceus europaeus	98.79	0.00e+00	1070.00
IUUC-Fca-036030	Felis catus	85.55	0.00e+00	1207.00
IUUC-Fal-036696	Ficedula albicollis	97.11	0.00e+00	1255.00
IUUC-Gmo-038805	Gadus morhua	82.39	0.00e+00	1195.00
IUUC-Gga-041113	Gallus gallus	97.28	0.00e+00	1340.00
IUUC-Gac-041999	Gasterosteus aculeatus	81.86	0.00e+00	1186.00
IUUC-Ggo-045164	Gorilla gorilla	96.51	0.00e+00	1289.00
IUUC-Hsa-047011	Homo sapiens	96.51	0.00e+00	1289.00
IUUC-Itr-048040	Ictidomys tridecemlineatus	96.29	0.00e+00	1244.00
IUUC-Lch-050437	Latimeria chalumnae	93.25	0.00e+00	1115.00
IUUC-Loc-052819	Lepisosteus oculatus	93.68	0.00e+00	1221.00
IUUC-Laf-053862	Loxodonta africana	96.51	0.00e+00	1253.00
IUUC-Mcc-055735	Macaca mulatta	92.45	0.00e+00	1271.00
IUUC-Meu-056209	Macropus eugenii	81.61	0.00e+00	1182.00
IUUC-Mmr-061207	Microcebus murinus	97.80	0.00e+00	1244.00
IUUC-Mdo-062493	Monodelphis domestica	97.55	0.00e+00	1333.00
IUUC-Mmu-063795	Mus musculus	95.75	0.00e+00	1244.00
IUUC-Mpu-065819	Mustela putorius furo	96.26	0.00e+00	1299.00
IUUC-Mlu-067047	Myotis lucifugus	96.77	0.00e+00	1257.00
IUUC-Nle-069684	Nomascus leucogenys	96.38	0.00e+00	1283.00
IUUC-Opr-071172	Ochotona princeps	95.48	0.00e+00	1250.00
IUUC-Ont-072102	Oreochromis niloticus	81.00	0.00e+00	1176.00
IUUC-Oan-072842	Ornithorhynchus anatinus	83.42	0.00e+00	1170.00
IUUC-Ocu-074592	Oryctolagus cuniculus	92.76	0.00e+00	1275.00
IUUC-Ola-087267	Oryzias latipes	78.73	0.00e+00	1089.00
IUUC-Oga-088629	Otolemur garnettii	96.64	0.00e+00	1246.00
IUUC-Oar-089551	Ovis aries	96.13	0.00e+00	1261.00
IUUC-Ptr-091207	Pan troglodytes	96.12	0.00e+00	1283.00
IUUC-Pan-091822	Papio anubis	92.45	0.00e+00	1271.00
IUUC-Pfo-096239	Poecilia formosa	81.60	0.00e+00	1186.00
IUUC-Pab-097687	Pongo abelii	96.51	0.00e+00	1289.00
IUUC-Pca-100675	Procavia capensis	98.25	0.00e+00	1053.00
IUUC-Pva-102355	Pteropus vampyrus	93.11	0.00e+00	1184.00
IUUC-Rno-106027	Rattus norvegicus	94.33	0.00e+00	1279.00
IUUC-Sha-107419	Sarcophilus harrisii	94.90	0.00e+00	1272.00
IUUC-Sar-113585	Sorex araneus	85.78	0.00e+00	707.00
IUUC-Ssc-116151	Sus scrofa	96.64	0.00e+00	1273.00
IUUC-Tgu-117387	Taeniopygia guttata	96.51	0.00e+00	1311.00
IUUC-Tru-118051	Takifugu rubripes	78.44	0.00e+00	1142.00
IUUC-Tsy-119342	Tarsius syrichta	87.78	0.00e+00	1001.00
IUUC-Tbe-127881	Tupaia belangeri	93.67	0.00e+00	1257.00
IUUC-Ttr-129082	Tursiops truncatus	87.60	0.00e+00	1120.00
IUUC-Vpa-130577	Vicugna pacos	71.37	2.00e-151	529.00
IUUC-Xtr-131792	Xenopus tropicalis	89.60	0.00e+00	1212.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence