iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aml-001257

Ensembl Protein ID

ENSAMEP00000008860.1

UniProt Accession

D2HIB4; D2HIB4_AILME

Genbank Protein ID

EFB14636.1

Protein Name

Putative uncharacterized protein

Genbank Nucleotide ID

ACTA01098765

Gene Name

RNF144B; PANDA_010926

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000008424.1	ENSAMET00000009237.1	ENSAMEP00000008860.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RBR	3.90e-51	174.4	30	222

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RBR

   S: 1    CkvCllelsveeltvlleCehtfCkeClkqylelkikegqvteiscpaaecpek..leeseikellveeelykryekllleevveadaal 88
           Ck+Cl+e+s +++t+l+eC++ fC++Clkqyl+l+i+eg+ + i cp++ c ++  l+e+ei++ lv  ++++ y++l++e++v+ d+ +
   Q: 30   CKLCLCEQSLDKMTTLQECRCLFCTACLKQYLQLAIREGCGSPIACPDTVCLNHgtLQEAEIAC-LVPVDQFQLYQRLKFEREVHLDPYR 118
           ***************************************************9988899******.6999********************* PP
   S: 89   kwcpapdCslvvllekea..eklevecekcgkefCveCkeewHeglsCkelkeklakteeekeeaeskelleanskkCpkCkvyiekneg 176
           +wcp +dC++v+ +++++  + ++vec++c+ +fC++Ck++wH+++sC+e +  +  te   + a   + +ea +k+Cp C+vyie+neg
   Q: 119  TWCPVADCQTVCSVASSDpgQPVQVECPSCHLKFCSCCKDAWHTEVSCRESQPIVLPTE---HGALFGTDTEAPIKQCPVCRVYIERNEG 205
           *************9998877889999*****************************9999...89************************** PP
   S: 177  CnhmtCakCkaefCwlC 193
           C++m+C++Ck++fCw+C
   Q: 206  CAQMMCKNCKHTFCWYC 222
           ***************** PP

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

MGSGGRLQYL TMTTENPTAG DLAPAPLVTC KLCLCEQSLD KMTTLQECRC LFCTACLKQY 60
LQLAIREGCG SPIACPDTVC LNHGTLQEAE IACLVPVDQF QLYQRLKFER EVHLDPYRTW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGCTCAG GTGGGAGGTT GCAGTATCTC ACCATGACCA CCGAAAATCC GACGGCGGGA 60
GACCTGGCTC CAGCCCCCCT TGTCACTTGC AAACTCTGCT TGTGCGAACA GTCCCTGGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR016150--Casein_kin_II_reg-sub_b-sht
IPR031127--E3_UB_ligase_RBR
IPR002867--IBR_dom
IPR001841--Znf_RING
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1

Pfam

PF01485--IBR

SMART

SM00647--IBR
SM00184--RING

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0031966--C:mitochondrial membrane
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

KEGG

aml:100481429

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Atr-002709	Amborella trichopoda	28.14	6.00e-18	86.30
IUUC-Apl-004112	Anas platyrhynchos	81.49	7.00e-130	456.00
IUUC-Aca-004533	Anolis carolinensis	76.90	2.00e-138	484.00
IUUC-Aly-006073	Arabidopsis lyrata	30.21	2.00e-13	69.30
IUUC-Ath-007704	Arabidopsis thaliana	29.90	4.00e-14	72.40
IUUC-Bta-012641	Bos taurus	92.43	4.00e-165	573.00
IUUC-Bol-016316	Brassica oleracea	29.90	2.00e-16	80.90
IUUC-Cja-019626	Callithrix jacchus	79.21	3.00e-140	491.00
IUUC-Cfa-020702	Canis familiaris	96.04	2.00e-173	601.00
IUUC-Cpo-022147	Cavia porcellus	93.07	3.00e-166	577.00
IUUC-Csa-023473	Chlorocebus sabaeus	93.40	2.00e-170	591.00
IUUC-Cho-024298	Choloepus hoffmanni	89.11	2.00e-137	481.00
IUUC-Dre-028099	Danio rerio	65.79	6.00e-93	333.00
IUUC-Dno-029122	Dasypus novemcinctus	85.86	2.00e-153	534.00
IUUC-Dor-030669	Dipodomys ordii	93.99	1.00e-131	461.00
IUUC-Ete-033141	Echinops telfairi	79.21	9.00e-129	452.00
IUUC-Eca-034360	Equus caballus	95.05	2.00e-171	594.00
IUUC-Eeu-034538	Erinaceus europaeus	73.24	1.00e-85	308.00
IUUC-Fca-036055	Felis catus	93.73	2.00e-168	584.00
IUUC-Fal-037339	Ficedula albicollis	80.29	1.00e-132	465.00
IUUC-Gmo-038780	Gadus morhua	61.54	8.00e-86	310.00
IUUC-Gga-040256	Gallus gallus	79.72	3.00e-133	467.00
IUUC-Gac-042127	Gasterosteus aculeatus	63.21	3.00e-92	331.00
IUUC-Ggo-044867	Gorilla gorilla	94.72	1.00e-171	595.00
IUUC-Hsa-046928	Homo sapiens	94.39	3.00e-171	593.00
IUUC-Hvu-047484	Hordeum vulgare	29.81	3.00e-17	83.20
IUUC-Itr-048250	Ictidomys tridecemlineatus	95.85	4.00e-109	386.00
IUUC-Lch-050168	Latimeria chalumnae	74.10	2.00e-132	464.00
IUUC-Lpe-051649	Leersia perrieri	28.71	2.00e-17	84.30
IUUC-Loc-052150	Lepisosteus oculatus	59.86	5.00e-87	313.00
IUUC-Laf-053967	Loxodonta africana	92.41	8.00e-167	578.00
IUUC-Mcc-055898	Macaca mulatta	93.40	2.00e-170	591.00
IUUC-Meu-056628	Macropus eugenii	96.15	5.00e-43	167.00
IUUC-Mtr-057989	Medicago truncatula	26.42	6.00e-19	87.80
IUUC-Mga-059820	Meleagris gallopavo	78.65	1.00e-131	461.00
IUUC-Mmr-060680	Microcebus murinus	92.08	5.00e-165	573.00
IUUC-Mdo-062839	Monodelphis domestica	84.21	3.00e-152	530.00
IUUC-Mmu-063339	Mus musculus	86.14	1.00e-146	511.00
IUUC-Mac-065414	Musa acuminata	28.91	3.00e-19	89.00
IUUC-Mpu-065973	Mustela putorius furo	96.04	7.00e-174	602.00
IUUC-Mlu-067112	Myotis lucifugus	92.08	7.00e-158	549.00
IUUC-Nle-069795	Nomascus leucogenys	94.06	3.00e-171	594.00
IUUC-Opr-070390	Ochotona princeps	86.47	2.00e-150	524.00
IUUC-Ont-072329	Oreochromis niloticus	62.08	4.00e-89	321.00
IUUC-Oan-072980	Ornithorhynchus anatinus	78.57	4.00e-138	483.00
IUUC-Ocu-073845	Oryctolagus cuniculus	93.07	2.00e-167	581.00
IUUC-Ola-086872	Oryzias latipes	59.72	4.00e-85	307.00
IUUC-Oga-088954	Otolemur garnettii	93.07	5.00e-168	583.00
IUUC-Oar-089879	Ovis aries	92.43	4.00e-165	573.00
IUUC-Ptr-090685	Pan troglodytes	94.39	3.00e-171	593.00
IUUC-Pan-092086	Papio anubis	93.07	2.00e-170	590.00
IUUC-Psi-093481	Pelodiscus sinensis	81.19	2.00e-138	484.00
IUUC-Pfo-096065	Poecilia formosa	65.53	2.00e-92	332.00
IUUC-Pab-098031	Pongo abelii	93.73	7.00e-170	589.00
IUUC-Pop-099816	Populus trichocarpa	26.48	1.00e-15	77.80
IUUC-Pca-100936	Procavia capensis	90.10	3.00e-162	563.00
IUUC-Pva-102864	Pteropus vampyrus	82.84	5.00e-145	506.00
IUUC-Rno-105503	Rattus norvegicus	86.47	4.00e-147	513.00
IUUC-Sha-107425	Sarcophilus harrisii	84.87	2.00e-153	534.00
IUUC-Stu-112736	Solanum tuberosum	27.83	3.00e-18	85.50
IUUC-Ssc-115458	Sus scrofa	91.53	2.00e-154	538.00
IUUC-Tgu-117226	Taeniopygia guttata	79.21	3.00e-132	464.00
IUUC-Tru-118362	Takifugu rubripes	64.66	3.00e-93	334.00
IUUC-Tsy-119255	Tarsius syrichta	93.40	2.00e-168	584.00
IUUC-Tni-120140	Tetraodon nigroviridis	62.09	2.00e-88	318.00
IUUC-Tae-124420	Triticum aestivum	31.47	1.00e-18	87.80
IUUC-Tbe-127306	Tupaia belangeri	92.74	2.00e-166	577.00
IUUC-Ttr-128923	Tursiops truncatus	92.11	1.00e-153	535.00
IUUC-Vpa-130148	Vicugna pacos	92.08	9.00e-165	572.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence