iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-004141

Ensembl Protein ID

ENSAPLP00000000531.1

UniProt Accession

R0KAA7; R0KAA7_ANAPL

Genbank Protein ID

EOB07246.1

Protein Name

Histone demethylase JARID1A

Genbank Nucleotide ID

ADON01016821

Gene Name

KDM5A; Anapl_12876

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000000585.1	ENSAPLT00000001099.1	ENSAPLP00000000531.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	2.60e-19	68.9	239	286

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCrs 53
           vCl+Cg+g +++ +l+ C+ C++ +H  Cl ++  +++p+ + w CpkC +
   Q: 239  VCLFCGRGNNED-KLLLCDGCDDSYHTFCLIPP-LPDVPKGD-WRCPKCVA 286
           8*********88.6*******************.*******7.******75 PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

DWQPPFACEV QSFRFTPRIQ RLNELEAMTR VKLDFLDQLA KFWELQGSNL KIPVVERKIL 60
DLYGLSKIVA SKGGFEVVTK EKKWSKVASR LGYLPGKGTG SLLKSHYERI LYPYELFQSG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GACTGGCAGC CTCCATTTGC CTGTGAAGTA CAAAGTTTTC GTTTCACTCC ACGAATTCAG 60
CGCCTGAATG AGCTGGAGGT GAGCTTTTCC ACTGTTGATA CAATTTTGTG TTTGCGCTGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001606--ARID_dom
IPR003347--JmjC_dom
IPR013637--Lys_sp_deMease-like_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR004198--Znf_C5HC2
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51011--ARID
PS51184--JMJC
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF01388--ARID
PF02373--JmjC
PF00628--PHD
PF08429--PLU-1
PF02928--zf-C5HC2

SMART

SM00501--BRIGHT
SM00558--JmjC
SM00249--PHD

Gene Ontology

GO:0019907--C:cyclin-dependent protein kinase activating kinase holoenzyme complex
GO:0032993--C:protein-DNA complex
GO:0031490--F:chromatin DNA binding
GO:0008168--F:methyltransferase activity
GO:0016706--F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0003713--F:transcription coactivator activity
GO:0008270--F:zinc ion binding
GO:0032922--P:circadian regulation of gene expression
GO:0034720--P:histone H3-K4 demethylation
GO:1901726--P:negative regulation of histone deacetylase activity
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0045893--P:positive regulation of transcription, DNA-templated

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002061	Ailuropoda melanoleuca	92.12	0.00e+00	2758.00
IUUC-Atr-002595	Amborella trichopoda	30.07	2.00e-107	384.00
IUUC-Aca-004952	Anolis carolinensis	92.98	0.00e+00	2863.00
IUUC-Afl-008625	Aspergillus flavus	29.54	2.00e-116	414.00
IUUC-Afu-008796	Aspergillus fumigatus	29.93	1.00e-117	418.00
IUUC-Ate-010453	Aspergillus terreus	30.25	2.00e-114	407.00
IUUC-Ame-011323	Astyanax mexicanus	78.94	0.00e+00	1968.00
IUUC-Bta-012902	Bos taurus	91.29	0.00e+00	2789.00
IUUC-Cja-018988	Callithrix jacchus	90.15	0.00e+00	2657.00
IUUC-Cfa-020212	Canis familiaris	91.15	0.00e+00	2716.00
IUUC-Cpo-022221	Cavia porcellus	92.45	0.00e+00	2014.00
IUUC-Csa-023575	Chlorocebus sabaeus	92.60	0.00e+00	2696.00
IUUC-Cho-024280	Choloepus hoffmanni	87.48	0.00e+00	2543.00
IUUC-Cin-025321	Ciona intestinalis	49.32	0.00e+00	1097.00
IUUC-Csv-026185	Ciona savignyi	46.73	0.00e+00	1097.00
IUUC-Cgl-026613	Colletotrichum gloeosporioides	28.67	2.00e-110	394.00
IUUC-Dre-027909	Danio rerio	76.24	0.00e+00	1676.00
IUUC-Dno-029473	Dasypus novemcinctus	91.96	0.00e+00	2615.00
IUUC-Dor-030281	Dipodomys ordii	90.28	0.00e+00	1202.00
IUUC-Dse-031479	Dothistroma septosporum	31.02	4.00e-107	383.00
IUUC-Dme-032021	Drosophila melanogaster	45.84	0.00e+00	1059.00
IUUC-Eca-034265	Equus caballus	91.88	0.00e+00	2788.00
IUUC-Eeu-034692	Erinaceus europaeus	58.15	0.00e+00	1120.00
IUUC-Fca-035476	Felis catus	90.96	0.00e+00	2751.00
IUUC-Fal-037078	Ficedula albicollis	98.09	0.00e+00	2596.00
IUUC-Gmo-039140	Gadus morhua	53.62	0.00e+00	1310.00
IUUC-Gga-040466	Gallus gallus	97.82	0.00e+00	2992.00
IUUC-Gac-042566	Gasterosteus aculeatus	73.20	0.00e+00	2133.00
IUUC-Ggo-044524	Gorilla gorilla	85.82	0.00e+00	2405.00
IUUC-Hsa-045821	Homo sapiens	92.37	0.00e+00	2786.00
IUUC-Itr-048348	Ictidomys tridecemlineatus	56.42	0.00e+00	1369.00
IUUC-Kpa-049245	Komagataella pastoris	21.39	2.00e-31	132.00
IUUC-Lch-050630	Latimeria chalumnae	75.52	0.00e+00	2084.00
IUUC-Lpe-051537	Leersia perrieri	31.16	6.00e-90	326.00
IUUC-Loc-051963	Lepisosteus oculatus	77.07	0.00e+00	2071.00
IUUC-Laf-053918	Loxodonta africana	85.00	0.00e+00	2388.00
IUUC-Mcc-055672	Macaca mulatta	90.97	0.00e+00	2788.00
IUUC-Meu-056643	Macropus eugenii	55.77	0.00e+00	1359.00
IUUC-Mor-057198	Magnaporthe oryzae	30.22	1.00e-117	418.00
IUUC-Mtr-058113	Medicago truncatula	30.91	1.00e-92	335.00
IUUC-Mga-059192	Meleagris gallopavo	89.59	0.00e+00	2630.00
IUUC-Mmr-060968	Microcebus murinus	90.43	0.00e+00	2776.00
IUUC-Mdo-062945	Monodelphis domestica	93.30	0.00e+00	2705.00
IUUC-Mmu-063614	Mus musculus	91.39	0.00e+00	2767.00
IUUC-Mpu-066349	Mustela putorius furo	92.28	0.00e+00	2664.00
IUUC-Mlu-067363	Myotis lucifugus	91.58	0.00e+00	2819.00
IUUC-Nle-070142	Nomascus leucogenys	92.37	0.00e+00	2799.00
IUUC-Opr-071002	Ochotona princeps	85.81	0.00e+00	1354.00
IUUC-Ont-072471	Oreochromis niloticus	78.68	0.00e+00	1920.00
IUUC-Oan-072797	Ornithorhynchus anatinus	78.14	0.00e+00	1952.00
IUUC-Ocu-074164	Oryctolagus cuniculus	91.10	0.00e+00	2831.00
IUUC-Ola-087076	Oryzias latipes	74.74	0.00e+00	2066.00
IUUC-Olu-087633	Ostreococcus lucimarinus	23.35	2.00e-09	57.40
IUUC-Oga-088350	Otolemur garnettii	90.17	0.00e+00	2704.00
IUUC-Oar-090045	Ovis aries	91.29	0.00e+00	2793.00
IUUC-Ptr-091199	Pan troglodytes	91.82	0.00e+00	2778.00
IUUC-Pan-092094	Papio anubis	87.63	0.00e+00	2732.00
IUUC-Psi-093550	Pelodiscus sinensis	94.87	0.00e+00	2848.00
IUUC-Pma-094137	Petromyzon marinus	52.66	0.00e+00	1262.00
IUUC-Pno-094879	Phaeosphaeria nodorum	29.42	6.00e-119	422.00
IUUC-Pfo-097266	Poecilia formosa	75.39	0.00e+00	2094.00
IUUC-Pab-098576	Pongo abelii	92.49	0.00e+00	2788.00
IUUC-Pca-100123	Procavia capensis	89.60	0.00e+00	1594.00
IUUC-Pva-103109	Pteropus vampyrus	86.39	0.00e+00	2599.00
IUUC-Pte-104195	Pyrenophora teres	29.38	8.00e-124	438.00
IUUC-Pyt-104566	Pyrenophora triticirepentis	29.84	2.00e-125	444.00
IUUC-Rno-105664	Rattus norvegicus	91.51	0.00e+00	2768.00
IUUC-Sha-107506	Sarcophilus harrisii	92.21	0.00e+00	2525.00
IUUC-Sja-107734	Schizosaccharomyces japonicus	21.12	2.00e-34	141.00
IUUC-Spo-108283	Schizosaccharomyces pombe	22.87	1.00e-54	209.00
IUUC-Smo-108843	Selaginella moellendorffii	52.08	9.00e-11	62.00
IUUC-Sit-110534	Setaria italica	31.47	4.00e-102	367.00
IUUC-Sar-113052	Sorex araneus	90.54	0.00e+00	2751.00
IUUC-Sre-115161	Sporisorium reilianum	29.11	7.00e-122	432.00
IUUC-Ssc-116354	Sus scrofa	56.42	0.00e+00	1357.00
IUUC-Tgu-116613	Taeniopygia guttata	98.11	0.00e+00	2948.00
IUUC-Tru-118604	Takifugu rubripes	75.36	0.00e+00	2123.00
IUUC-Tni-120779	Tetraodon nigroviridis	75.14	0.00e+00	2106.00
IUUC-Tre-122213	Trichoderma reesei	29.67	3.00e-114	406.00
IUUC-Tvi-122263	Trichoderma virens	29.42	1.00e-110	395.00
IUUC-Tme-127087	Tuber melanosporum	34.23	7.00e-121	429.00
IUUC-Ttr-129242	Tursiops truncatus	89.87	0.00e+00	2689.00
IUUC-Uma-129590	Ustilago maydis	29.23	2.00e-121	431.00
IUUC-Vpa-130429	Vicugna pacos	85.70	0.00e+00	1403.00
IUUC-Vvi-131071	Vitis vinifera	29.70	3.00e-81	296.00
IUUC-Xtr-131762	Xenopus tropicalis	76.09	0.00e+00	2100.00
IUUC-Xma-133693	Xiphophorus maculatus	75.50	0.00e+00	2115.00
IUUC-Zma-135829	Zea mays	28.13	2.00e-102	368.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence