iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGALG00000013410.5	ENSGALT00000021875.4	ENSGALP00000021837.3
ENSGALG00000013410.5	ENSGALT00000054129.1	ENSGALP00000052128.1
ENSGALG00000013410.5	ENSGALT00000068309.1	ENSGALP00000049231.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	6.30e-88	296.1	59	236

Active Site

Position(s)	Description	Evidence
218	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 16   lksakvllvGagglGcEllKnLvlaGvgsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvnveaheesiteleeei 104
           l+++kvl++GagglGcEllKnL+l+G+++i+v+Dmdt++vsnlnrqFLfr++dvg++KAevaae+l+ + p++ v+a+           
   Q: 59   LSTCKVLVIGAGGLGCELLKNLALSGFRQIHVIDMDTIDVSNLNRQFLFRPKDVGRPKAEVAAEFLNSRIPSCAVVAYP---------- 137
           789************************************************************************9973.......... PP
   S: 105  vFfkkfdvVvlaldnrearrkvnrlclna............rvpliesgtlGllGqvrviikgltecyscsd..dppqktiPfctlket 179
               +f+++v++ld++ arr++n ++++              +pli++gt+G++G++rvii+g+t+c +c+   +ppq+++P+ct++++
   Q: 138  ---FRFHIIVCGLDSIIARRWINGMLMSFlryedgvldpssIIPLIDGGTEGFKGNARVIIPGMTACVECTLelYPPQVNFPMCTIASM 223
           ...279*********************************************************************************** PP
   S: 180  pnaaehtiewavl 192
           p+ +eh+ie++++
   Q: 224  PRLPEHCIEYVRI 236
           **********933 PP

Organism

Gallus gallus

Protein Sequence
(Fasta)

SSQIVTSNRL RRQMAVDGGY GDSGDWEGRW NHVKKFLERS GPFTHPDFEP GTQALDFLLS 60
TCKVLVIGAG GLGCELLKNL ALSGFRQIHV IDMDTIDVSN LNRQFLFRPK DVGRPKAEVA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCAAGTCAGA TAGTAACTTC TAACAGGCTC AGGAGACAGC TGGAAAATGA GGGTGTCATG 60
AATACCATGG TATTCATGGC AGGTAAAGAT CGTTCAAAAT TCATACCTTT TCATAGTTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR014929--E2_binding
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR030468--Uba3
IPR033127--UBQ-activ_enz_E1_Cys_AS

PROSITE

PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF08825--E2_bind
PF00899--ThiF

SMART

SM01181--E2_bind

Gene Ontology

GO:0005634--C:nucleus
GO:0016881--F:acid-amino acid ligase activity
GO:0005524--F:ATP binding
GO:0019781--F:NEDD8 activating enzyme activity
GO:0007113--P:endomitotic cell cycle
GO:0045116--P:protein neddylation
GO:0051726--P:regulation of cell cycle

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001124	Aegilops tauschii	47.63	7.00e-75	273.00
IUUC-Aml-001578	Ailuropoda melanoleuca	87.44	0.00e+00	822.00
IUUC-Atr-002591	Amborella trichopoda	49.63	7.00e-88	317.00
IUUC-Apl-003671	Anas platyrhynchos	93.91	0.00e+00	854.00
IUUC-Aca-004749	Anolis carolinensis	89.70	0.00e+00	800.00
IUUC-Aly-005747	Arabidopsis lyrata	47.15	2.00e-93	335.00
IUUC-Ath-006623	Arabidopsis thaliana	47.39	5.00e-93	334.00
IUUC-Ago-007934	Ashbya gossypii	44.13	1.00e-69	256.00
IUUC-Acl-008047	Aspergillus clavatus	48.49	3.00e-116	411.00
IUUC-Afl-008615	Aspergillus flavus	42.56	7.00e-73	267.00
IUUC-Afu-008996	Aspergillus fumigatus	49.30	1.00e-109	389.00
IUUC-Ani-009281	Aspergillus nidulans	41.88	7.00e-78	283.00
IUUC-Ang-009539	Aspergillus niger	49.65	4.00e-107	381.00
IUUC-Aor-010151	Aspergillus oryzae	47.23	6.00e-103	367.00
IUUC-Ate-010502	Aspergillus terreus	50.12	3.00e-108	385.00
IUUC-Ame-011837	Astyanax mexicanus	81.61	0.00e+00	738.00
IUUC-Bgr-012068	Blumeria graminis	47.38	1.00e-103	370.00
IUUC-Bta-013003	Bos taurus	88.69	0.00e+00	822.00
IUUC-Bci-013983	Botrytis cinerea	51.04	1.00e-117	416.00
IUUC-Bdi-014429	Brachypodium distachyon	47.51	2.00e-81	296.00
IUUC-Bol-015813	Brassica oleracea	48.14	9.00e-86	310.00
IUUC-Bra-018023	Brassica rapa	47.89	1.00e-83	303.00
IUUC-Cel-018684	Caenorhabditis elegans	50.93	5.00e-122	430.00
IUUC-Cja-019200	Callithrix jacchus	88.74	0.00e+00	815.00
IUUC-Cfa-021038	Canis familiaris	88.69	0.00e+00	823.00
IUUC-Cre-022778	Chlamydomonas reinhardtii	47.58	4.00e-102	364.00
IUUC-Csa-024079	Chlorocebus sabaeus	88.01	0.00e+00	821.00
IUUC-Cho-025052	Choloepus hoffmanni	80.32	0.00e+00	729.00
IUUC-Cin-025113	Ciona intestinalis	65.90	1.00e-170	592.00
IUUC-Csv-026231	Ciona savignyi	62.44	1.00e-167	582.00
IUUC-Cgl-026535	Colletotrichum gloeosporioides	50.70	9.00e-119	420.00
IUUC-Cne-026850	Cryptococcus neoformans	47.76	3.00e-105	375.00
IUUC-Cme-027275	Cyanidioschyzon merolae	35.77	5.00e-67	248.00
IUUC-Dre-028751	Danio rerio	81.17	0.00e+00	748.00
IUUC-Dno-029571	Dasypus novemcinctus	89.14	0.00e+00	824.00
IUUC-Dor-030395	Dipodomys ordii	86.65	0.00e+00	791.00
IUUC-Dse-031329	Dothistroma septosporum	46.00	9.00e-103	367.00
IUUC-Dme-031776	Drosophila melanogaster	60.32	5.00e-149	520.00
IUUC-Ete-032894	Echinops telfairi	70.00	1.00e-62	233.00
IUUC-Eca-034389	Equus caballus	88.46	0.00e+00	820.00
IUUC-Eeu-035152	Erinaceus europaeus	80.10	0.00e+00	647.00
IUUC-Fca-036032	Felis catus	88.12	0.00e+00	825.00
IUUC-Fal-037506	Ficedula albicollis	94.58	0.00e+00	863.00
IUUC-Fox-037871	Fusarium oxysporum	51.19	5.00e-103	367.00
IUUC-Fso-038350	Fusarium solani	51.16	1.00e-116	413.00
IUUC-Gmo-039246	Gadus morhua	77.58	0.00e+00	708.00
IUUC-Ggr-039859	Gaeumannomyces graminis	51.44	2.00e-111	395.00
IUUC-Gac-042601	Gasterosteus aculeatus	79.82	0.00e+00	735.00
IUUC-Gma-042744	Glycine max	50.39	7.00e-86	310.00
IUUC-Ggo-044788	Gorilla gorilla	88.04	0.00e+00	813.00
IUUC-Hsa-045849	Homo sapiens	88.46	0.00e+00	822.00
IUUC-Hvu-047819	Hordeum vulgare	49.86	4.00e-76	278.00
IUUC-Itr-047863	Ictidomys tridecemlineatus	88.49	0.00e+00	823.00
IUUC-Kpa-049393	Komagataella pastoris	51.06	6.00e-92	330.00
IUUC-Lch-049471	Latimeria chalumnae	85.20	0.00e+00	775.00
IUUC-Lpe-051297	Leersia perrieri	46.63	6.00e-91	327.00
IUUC-Loc-052910	Lepisosteus oculatus	84.72	0.00e+00	764.00
IUUC-Lma-053181	Leptosphaeria maculans	49.89	4.00e-118	417.00
IUUC-Laf-054314	Loxodonta africana	88.12	0.00e+00	824.00
IUUC-Mcc-054870	Macaca mulatta	88.46	0.00e+00	822.00
IUUC-Meu-056574	Macropus eugenii	76.39	7.00e-128	450.00
IUUC-Mor-056919	Magnaporthe oryzae	51.16	7.00e-115	406.00
IUUC-Mpo-057614	Magnaporthe poae	51.55	8.00e-112	396.00
IUUC-Mtr-058110	Medicago truncatula	49.36	1.00e-83	303.00
IUUC-Mla-058949	Melampsora laricipopulina	50.12	5.00e-108	384.00
IUUC-Mga-059455	Meleagris gallopavo	96.16	0.00e+00	877.00
IUUC-Mvi-060270	Microbotryum violaceum	49.10	4.00e-112	397.00
IUUC-Mmr-061155	Microcebus murinus	86.44	0.00e+00	769.00
IUUC-Mdo-062037	Monodelphis domestica	88.99	0.00e+00	791.00
IUUC-Mmu-063670	Mus musculus	88.44	0.00e+00	819.00
IUUC-Mac-064711	Musa acuminata	46.90	9.00e-81	293.00
IUUC-Mpu-066734	Mustela putorius furo	88.09	0.00e+00	818.00
IUUC-Mlu-067068	Myotis lucifugus	88.06	0.00e+00	790.00
IUUC-Nfi-068349	Neosartorya fischeri	49.06	4.00e-109	387.00
IUUC-Ncr-068626	Neurospora crassa	49.62	6.00e-106	377.00
IUUC-Nle-069366	Nomascus leucogenys	81.08	0.00e+00	736.00
IUUC-Opr-070993	Ochotona princeps	92.31	1.00e-68	253.00
IUUC-Ont-072196	Oreochromis niloticus	80.49	0.00e+00	728.00
IUUC-Oan-073511	Ornithorhynchus anatinus	86.62	0.00e+00	805.00
IUUC-Ocu-073773	Oryctolagus cuniculus	88.69	0.00e+00	823.00
IUUC-Oba-075726	Oryza barthii	43.60	1.00e-78	286.00
IUUC-Obr-076286	Oryza brachyantha	46.39	3.00e-87	315.00
IUUC-Ogu-078473	Oryza glumaepatula	43.60	1.00e-78	286.00
IUUC-Oin-079393	Oryza indica	48.51	1.00e-92	333.00
IUUC-Olo-080446	Oryza longistaminata	45.19	3.00e-82	298.00
IUUC-Ome-081737	Oryza meridionalis	45.77	5.00e-82	298.00
IUUC-Oni-082853	Oryza nivara	43.60	1.00e-78	286.00
IUUC-Opu-083590	Oryza punctata	47.60	4.00e-92	331.00
IUUC-Oru-084184	Oryza rufipogon	43.60	1.00e-78	286.00
IUUC-Osa-085402	Oryza sativa	48.51	1.00e-92	333.00
IUUC-Ola-086615	Oryzias latipes	75.34	0.00e+00	681.00
IUUC-Olu-087738	Ostreococcus lucimarinus	48.89	1.00e-90	326.00
IUUC-Oga-088101	Otolemur garnettii	88.01	0.00e+00	819.00
IUUC-Oar-090293	Ovis aries	88.39	0.00e+00	829.00
IUUC-Ptr-090503	Pan troglodytes	88.46	0.00e+00	822.00
IUUC-Pan-092477	Papio anubis	86.07	0.00e+00	792.00
IUUC-Psi-093442	Pelodiscus sinensis	91.16	0.00e+00	838.00
IUUC-Pma-094247	Petromyzon marinus	78.57	0.00e+00	734.00
IUUC-Pno-094780	Phaeosphaeria nodorum	50.00	1.00e-110	393.00
IUUC-Ppa-095338	Physcomitrella patens	49.05	2.00e-112	399.00
IUUC-Pfo-097137	Poecilia formosa	80.27	0.00e+00	725.00
IUUC-Pab-098060	Pongo abelii	88.01	0.00e+00	782.00
IUUC-Pop-099470	Populus trichocarpa	47.44	2.00e-89	322.00
IUUC-Pca-100500	Procavia capensis	76.70	0.00e+00	690.00
IUUC-Ppe-102008	Prunus persica	48.46	5.00e-81	294.00
IUUC-Pva-103095	Pteropus vampyrus	84.29	3.00e-106	378.00
IUUC-Pgr-103666	Puccinia graminis	48.26	2.00e-108	385.00
IUUC-Ptt-103901	Puccinia triticina	47.82	2.00e-109	389.00
IUUC-Pte-104198	Pyrenophora teres	48.85	2.00e-115	408.00
IUUC-Pyt-104792	Pyrenophora triticirepentis	48.85	5.00e-113	400.00
IUUC-Rno-105446	Rattus norvegicus	88.44	0.00e+00	819.00
IUUC-Sce-106355	Saccharomyces cerevisiae	42.12	1.00e-66	246.00
IUUC-Sha-106664	Sarcophilus harrisii	87.36	0.00e+00	795.00
IUUC-Sja-107982	Schizosaccharomyces japonicus	41.63	8.00e-94	337.00
IUUC-Spo-108345	Schizosaccharomyces pombe	42.07	4.00e-92	331.00
IUUC-Ssl-108540	Sclerotinia sclerotiorum	46.74	1.00e-100	359.00
IUUC-Smo-109133	Selaginella moellendorffii	48.58	3.00e-110	391.00
IUUC-Sit-109724	Setaria italica	48.02	5.00e-84	305.00
IUUC-Sly-110916	Solanum lycopersicum	49.10	2.00e-92	332.00
IUUC-Stu-112236	Solanum tuberosum	48.84	4.00e-92	331.00
IUUC-Sar-113044	Sorex araneus	88.56	0.00e+00	735.00
IUUC-Sbi-114276	Sorghum bicolor	48.14	3.00e-84	305.00
IUUC-Sre-114963	Sporisorium reilianum	49.88	5.00e-112	397.00
IUUC-Ssc-116301	Sus scrofa	88.37	0.00e+00	828.00
IUUC-Tgu-117265	Taeniopygia guttata	94.58	0.00e+00	863.00
IUUC-Tru-117526	Takifugu rubripes	79.33	0.00e+00	719.00
IUUC-Tsy-119483	Tarsius syrichta	87.92	0.00e+00	761.00
IUUC-Tni-120363	Tetraodon nigroviridis	80.80	0.00e+00	707.00
IUUC-Tca-121731	Theobroma cacao	48.87	1.00e-84	306.00
IUUC-Tre-122221	Trichoderma reesei	51.73	4.00e-105	374.00
IUUC-Tvi-122352	Trichoderma virens	49.88	3.00e-117	414.00
IUUC-Tae-123864	Triticum aestivum	47.60	4.00e-85	308.00
IUUC-Tur-126070	Triticum urartu	44.58	1.00e-64	239.00
IUUC-Tme-127199	Tuber melanosporum	49.35	2.00e-103	369.00
IUUC-Tbe-128076	Tupaia belangeri	88.01	0.00e+00	820.00
IUUC-Ttr-128695	Tursiops truncatus	73.53	0.00e+00	658.00
IUUC-Uma-129638	Ustilago maydis	48.95	6.00e-110	390.00
IUUC-Vda-129963	Verticillium dahliae	51.61	3.00e-109	388.00
IUUC-Vpa-130637	Vicugna pacos	81.22	0.00e+00	731.00
IUUC-Vvi-131613	Vitis vinifera	48.72	1.00e-80	293.00
IUUC-Xtr-132924	Xenopus tropicalis	85.23	0.00e+00	765.00
IUUC-Xma-133356	Xiphophorus maculatus	80.27	0.00e+00	726.00
IUUC-Yli-134365	Yarrowia lipolytica	48.34	1.00e-99	356.00
IUUC-Zma-135941	Zea mays	43.69	2.00e-78	285.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence