iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-011876

Ensembl Protein ID

ENSAMXP00000014585.1

UniProt Accession

W5L423; W5L423_ASTMX

Genbank Protein ID

ENSAMXP00000014585

Protein Name

Tyrosine-protein kinase

Genbank Nucleotide ID

APWO01117706

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000014156.1	ENSAMXT00000014585.1	ENSAMXP00000014585.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	2.30e-15	56.5	80	135

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 6    vqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           + +lydyea ++d+L+++kG++ ++i  ++++++W+ + + ++g  G +P+n+v+ ++
   Q: 80   FVALYDYEARTEDDLSFQKGEKFQII--NSTEGDWWDARSLTTGGTGYIPSNYVAPVD 135
           789***********************..8999**********************9987 PP

Organism

Astyanax mexicanus

Protein Sequence
(Fasta)

MGCAQCKDKD SKLVESDGGQ CGTGPVCVRF NDPQQITVSA IPNYNNFHQA GGAQGVTVFG 60
GVSTHTGTLR TRGGTGVTLF VALYDYEART EDDLSFQKGE KFQIINSTEG DWWDARSLTT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGGGGGCGTG GCTTCACGGA ATACGGGTGT GGAAAAATCC ACGCCTCTCG CCATCATCCT 60
CCTCACCATC ATATGTTCCA GTGGAGAGCG GAGCGAGAGG AGCGCGCGCG CAGATGTTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0060027--P:convergent extension involved in gastrulation
GO:0031101--P:fin regeneration
GO:0045859--P:regulation of protein kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003716	Anas platyrhynchos	83.33	0.00e+00	891.00
IUUC-Aly-005712	Arabidopsis lyrata	33.91	8.00e-20	92.40
IUUC-Bol-016049	Brassica oleracea	32.95	4.00e-18	87.00
IUUC-Dno-030043	Dasypus novemcinctus	74.20	0.00e+00	843.00
IUUC-Fal-037320	Ficedula albicollis	83.64	0.00e+00	896.00
IUUC-Gga-041262	Gallus gallus	83.64	0.00e+00	896.00
IUUC-Mcc-055039	Macaca mulatta	82.32	0.00e+00	883.00
IUUC-Meu-056155	Macropus eugenii	77.11	0.00e+00	727.00
IUUC-Nle-068978	Nomascus leucogenys	83.09	0.00e+00	890.00
IUUC-Oga-088789	Otolemur garnettii	83.09	0.00e+00	889.00
IUUC-Tgu-117206	Taeniopygia guttata	83.64	0.00e+00	896.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence