iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mga-059293

Ensembl Protein ID

ENSMGAP00000015271.2

UniProt Accession

G1NNN5; G1NNN5_MELGA

Protein Name

Uncharacterized protein

Gene Name

DCAF6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000014428.2	ENSMGAT00000016220.2	ENSMGAP00000015271.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.70e-17	62.5	62	90

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf....sdtllvsGsdDgti 25
           gH + +++ +f    +d+ +vs+s+Dg+i
   Q: 62   GHRANIFSAKFlpctNDKQIVSCSGDGVI 90
           8************9777**********98 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

FTGRREFIQR LKLEATLNVH DGCVNTICWN DTGEYILSGS DDTNLVITNP YSRKVLTTIR 60
SGHRANIFSA KFLPCTNDKQ IVSCSGDGVI FYTNIEQDAE TNRQCQYTCH YGTTYEIMTV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTACAGGGA GAAGAGAATT TATCCAAAGA TTAAAACTTG AAGCAACCTT GAATGTGCAT 60
GATGGATGTG TAAGTTGCTT TGTTGCTTTT TTTTTGTTTG TTAAATGTTG TTAAATAGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR000048--IQ_motif_EF-hand-BS
IPR002469--Peptidase_S9B_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50096--IQ
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0080008--C:Cul4-RING E3 ubiquitin ligase complex
GO:0005829--C:cytosol
GO:0005925--C:focal adhesion
GO:0005634--C:nucleus
GO:0030374--F:ligand-dependent nuclear receptor transcription coactivator activity
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001399	Ailuropoda melanoleuca	82.05	0.00e+00	649.00
IUUC-Apl-003181	Anas platyrhynchos	90.06	0.00e+00	1342.00
IUUC-Aca-004953	Anolis carolinensis	66.57	0.00e+00	752.00
IUUC-Aly-005818	Arabidopsis lyrata	36.98	6.00e-38	151.00
IUUC-Acl-008211	Aspergillus clavatus	28.74	7.00e-27	115.00
IUUC-Afl-008592	Aspergillus flavus	28.40	1.00e-25	112.00
IUUC-Afu-008828	Aspergillus fumigatus	29.55	2.00e-26	114.00
IUUC-Ate-010555	Aspergillus terreus	27.46	1.00e-25	111.00
IUUC-Ame-011314	Astyanax mexicanus	76.34	3.00e-164	572.00
IUUC-Bta-013552	Bos taurus	74.21	0.00e+00	1103.00
IUUC-Cja-019015	Callithrix jacchus	83.26	0.00e+00	647.00
IUUC-Cfa-021249	Canis familiaris	83.72	0.00e+00	644.00
IUUC-Cpo-021903	Cavia porcellus	82.33	0.00e+00	642.00
IUUC-Csa-023744	Chlorocebus sabaeus	83.26	0.00e+00	651.00
IUUC-Cho-024527	Choloepus hoffmanni	69.65	3.00e-138	485.00
IUUC-Dre-028040	Danio rerio	81.33	6.00e-164	571.00
IUUC-Dno-029777	Dasypus novemcinctus	86.02	0.00e+00	644.00
IUUC-Dor-030879	Dipodomys ordii	71.33	6.00e-160	557.00
IUUC-Ete-032607	Echinops telfairi	70.13	3.00e-115	409.00
IUUC-Eca-033396	Equus caballus	76.60	0.00e+00	1091.00
IUUC-Eeu-034944	Erinaceus europaeus	56.54	5.00e-104	372.00
IUUC-Fca-036020	Felis catus	73.35	0.00e+00	1088.00
IUUC-Fal-037527	Ficedula albicollis	76.14	0.00e+00	1107.00
IUUC-Gmo-039347	Gadus morhua	77.81	7.00e-155	540.00
IUUC-Gga-040564	Gallus gallus	92.52	0.00e+00	1320.00
IUUC-Gac-042029	Gasterosteus aculeatus	79.22	2.00e-159	555.00
IUUC-Ggo-045634	Gorilla gorilla	70.56	1.00e-137	483.00
IUUC-Hsa-045743	Homo sapiens	77.45	0.00e+00	1115.00
IUUC-Itr-048064	Ictidomys tridecemlineatus	76.73	0.00e+00	1120.00
IUUC-Lch-050457	Latimeria chalumnae	79.36	4.00e-173	601.00
IUUC-Loc-052880	Lepisosteus oculatus	82.12	5.00e-164	571.00
IUUC-Lma-053032	Leptosphaeria maculans	30.06	1.00e-26	115.00
IUUC-Laf-053836	Loxodonta africana	69.39	0.00e+00	746.00
IUUC-Mcc-055749	Macaca mulatta	83.26	0.00e+00	650.00
IUUC-Mmr-060923	Microcebus murinus	83.49	0.00e+00	650.00
IUUC-Mdo-063056	Monodelphis domestica	75.90	0.00e+00	1101.00
IUUC-Mmu-063121	Mus musculus	75.18	0.00e+00	1117.00
IUUC-Mpu-066035	Mustela putorius furo	79.91	0.00e+00	634.00
IUUC-Mlu-067903	Myotis lucifugus	75.51	0.00e+00	1087.00
IUUC-Nfi-068606	Neosartorya fischeri	29.31	3.00e-26	114.00
IUUC-Nle-069415	Nomascus leucogenys	83.41	0.00e+00	650.00
IUUC-Opr-070809	Ochotona princeps	63.38	1.00e-103	370.00
IUUC-Ont-071470	Oreochromis niloticus	79.82	7.00e-160	557.00
IUUC-Oan-072748	Ornithorhynchus anatinus	84.71	1.00e-110	392.00
IUUC-Ocu-073865	Oryctolagus cuniculus	75.24	0.00e+00	1098.00
IUUC-Ola-086755	Oryzias latipes	78.61	3.00e-158	552.00
IUUC-Olu-087847	Ostreococcus lucimarinus	28.31	8.00e-23	100.00
IUUC-Oga-088309	Otolemur garnettii	80.78	1.00e-158	553.00
IUUC-Oar-090264	Ovis aries	82.56	0.00e+00	655.00
IUUC-Ptr-090603	Pan troglodytes	83.26	0.00e+00	651.00
IUUC-Pan-092480	Papio anubis	75.94	0.00e+00	1121.00
IUUC-Psi-092973	Pelodiscus sinensis	82.01	0.00e+00	969.00
IUUC-Pno-095149	Phaeosphaeria nodorum	38.96	9.00e-16	79.00
IUUC-Pfo-096506	Poecilia formosa	78.92	6.00e-158	550.00
IUUC-Pab-097581	Pongo abelii	69.98	0.00e+00	985.00
IUUC-Pca-100155	Procavia capensis	78.76	9.00e-161	560.00
IUUC-Pva-103022	Pteropus vampyrus	86.80	4.00e-179	621.00
IUUC-Pte-104187	Pyrenophora teres	29.20	1.00e-26	115.00
IUUC-Pyt-104546	Pyrenophora triticirepentis	29.33	2.00e-25	110.00
IUUC-Rno-105851	Rattus norvegicus	80.89	0.00e+00	641.00
IUUC-Sha-106790	Sarcophilus harrisii	72.26	0.00e+00	1089.00
IUUC-Sja-107779	Schizosaccharomyces japonicus	34.19	9.00e-33	135.00
IUUC-Spo-108129	Schizosaccharomyces pombe	33.81	3.00e-33	136.00
IUUC-Ssc-115674	Sus scrofa	96.13	8.00e-90	321.00
IUUC-Tgu-116760	Taeniopygia guttata	87.32	0.00e+00	1235.00
IUUC-Tru-118422	Takifugu rubripes	78.92	2.00e-157	549.00
IUUC-Tni-120340	Tetraodon nigroviridis	78.61	1.00e-156	546.00
IUUC-Tbe-127997	Tupaia belangeri	64.86	8.00e-131	461.00
IUUC-Ttr-129311	Tursiops truncatus	83.42	2.00e-174	605.00
IUUC-Vpa-130145	Vicugna pacos	81.97	0.00e+00	633.00
IUUC-Xtr-132496	Xenopus tropicalis	67.59	3.00e-173	601.00
IUUC-Xma-133610	Xiphophorus maculatus	73.73	6.00e-159	554.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence