iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-037497

Ensembl Protein ID

ENSFALP00000002048.1

UniProt Accession

U3JGZ4; U3JGZ4_FICAL

Genbank Protein ID

ENSFALP00000002048

Protein Name

tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4; WD repeat-containing protein 4

Genbank Nucleotide ID

AGTO01001429

Gene Name

WDR4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000001970.1	ENSFALT00000002060.1	ENSFALP00000002048.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.80e-07	31.0	156	194

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sd.tllvsGsdDgtikvWDlrtgvll 36
           gH + v+ + f   ++ +ll+s+s+D t+++W++++g  +
   Q: 156  GHREFVSKI-FvipNCpDLLLSASGDSTLRLWEYKSGEEV 194
           566667777.78854589***************9999876 PP

Organism

Ficedula albicollis

Functional Description
(View)

Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.

Protein Sequence
(Fasta)

ENLFVYDCSS AEKQPLGEKG QDGKGTDKGS DDILAFAFSP SGDYFALTDD NKRLILFRTK 60
PSWECVSVRF VNRRCTSLVI TAAEDKIFVA DKSGDVYSYS ITEPQADGKL ELGHVSLLLD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTGCCACTCT CCATAGTTAA GCTCCTGGTT GTTCTAGTGC CAGTAATTTT AGGTTTGTTT 60
TTCCCTTGCA GTGATGAGAA TCTCTTCGTG TACGATTGCA GCAGTGCAGA GAAACAGCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0819--tRNA processing
KW-0853--WD repeat

Interpro

IPR028884--Trm82
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0008176--F:tRNA (guanine-N7-)-methyltransferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000556	Aegilops tauschii	25.56	7.00e-09	54.70
IUUC-Apl-003975	Anas platyrhynchos	82.07	1.00e-174	605.00
IUUC-Aca-005170	Anolis carolinensis	68.33	4.00e-129	454.00
IUUC-Aly-005769	Arabidopsis lyrata	32.53	1.00e-27	117.00
IUUC-Ath-006733	Arabidopsis thaliana	30.58	5.00e-27	115.00
IUUC-Acl-008151	Aspergillus clavatus	40.00	5.00e-12	65.50
IUUC-Afl-008518	Aspergillus flavus	44.57	7.00e-14	71.20
IUUC-Afu-009102	Aspergillus fumigatus	27.55	2.00e-11	63.90
IUUC-Ani-009442	Aspergillus nidulans	30.35	3.00e-15	76.30
IUUC-Aor-010133	Aspergillus oryzae	30.99	9.00e-16	77.80
IUUC-Ate-010465	Aspergillus terreus	39.56	6.00e-13	68.60
IUUC-Ame-010613	Astyanax mexicanus	46.40	4.00e-94	338.00
IUUC-Bgr-012067	Blumeria graminis	32.89	1.00e-16	80.90
IUUC-Bta-012788	Bos taurus	57.73	3.00e-119	421.00
IUUC-Bdi-014458	Brachypodium distachyon	30.49	3.00e-16	79.30
IUUC-Bol-016398	Brassica oleracea	32.78	8.00e-27	114.00
IUUC-Bra-016644	Brassica rapa	33.99	4.00e-24	107.00
IUUC-Cpo-021963	Cavia porcellus	55.49	2.00e-110	392.00
IUUC-Csa-024148	Chlorocebus sabaeus	57.85	2.00e-106	378.00
IUUC-Cne-026834	Cryptococcus neoformans	40.46	3.00e-19	89.70
IUUC-Dre-028427	Danio rerio	47.20	2.00e-99	355.00
IUUC-Dno-028881	Dasypus novemcinctus	50.13	3.00e-106	378.00
IUUC-Dor-030522	Dipodomys ordii	53.68	1.00e-118	419.00
IUUC-Dme-032136	Drosophila melanogaster	39.88	2.00e-25	110.00
IUUC-Fca-035833	Felis catus	58.13	5.00e-124	437.00
IUUC-Gga-040547	Gallus gallus	77.19	3.00e-172	597.00
IUUC-Gac-041761	Gasterosteus aculeatus	43.27	2.00e-81	295.00
IUUC-Gma-043722	Glycine max	29.97	6.00e-24	104.00
IUUC-Ggo-045340	Gorilla gorilla	57.29	9.00e-113	399.00
IUUC-Hsa-046403	Homo sapiens	57.29	2.00e-112	399.00
IUUC-Hvu-047643	Hordeum vulgare	29.08	3.00e-18	86.30
IUUC-Itr-048103	Ictidomys tridecemlineatus	56.30	8.00e-121	426.00
IUUC-Kpa-049283	Komagataella pastoris	30.81	1.00e-17	83.60
IUUC-Lch-050682	Latimeria chalumnae	58.87	5.00e-124	437.00
IUUC-Lpe-050712	Leersia perrieri	30.89	2.00e-23	103.00
IUUC-Loc-052599	Lepisosteus oculatus	55.43	5.00e-122	430.00
IUUC-Laf-054390	Loxodonta africana	59.53	5.00e-124	437.00
IUUC-Mcc-054747	Macaca mulatta	58.38	9.00e-114	403.00
IUUC-Mtr-058600	Medicago truncatula	33.47	1.00e-27	117.00
IUUC-Mla-059129	Melampsora laricipopulina	26.35	2.00e-12	65.90
IUUC-Mga-059876	Meleagris gallopavo	80.65	6.00e-174	602.00
IUUC-Mvi-060359	Microbotryum violaceum	31.65	6.00e-12	65.90
IUUC-Mmr-061518	Microcebus murinus	56.27	2.00e-113	402.00
IUUC-Mac-065625	Musa acuminata	28.52	6.00e-23	101.00
IUUC-Nfi-068402	Neosartorya fischeri	27.24	1.00e-11	64.70
IUUC-Nle-069914	Nomascus leucogenys	56.02	1.00e-106	379.00
IUUC-Ont-071555	Oreochromis niloticus	44.60	1.00e-83	303.00
IUUC-Oan-072951	Ornithorhynchus anatinus	62.43	2.00e-136	478.00
IUUC-Ocu-074679	Oryctolagus cuniculus	56.89	7.00e-112	397.00
IUUC-Oba-075355	Oryza barthii	27.24	2.00e-14	73.90
IUUC-Obr-076769	Oryza brachyantha	31.52	6.00e-26	111.00
IUUC-Ogl-077168	Oryza glaberrima	31.50	5.00e-26	111.00
IUUC-Ogu-078275	Oryza glumaepatula	26.87	4.00e-14	72.40
IUUC-Oin-079207	Oryza indica	31.50	5.00e-26	111.00
IUUC-Oni-082437	Oryza nivara	27.11	5.00e-14	72.00
IUUC-Opu-084031	Oryza punctata	31.50	2.00e-24	106.00
IUUC-Oru-084380	Oryza rufipogon	27.24	4.00e-14	72.40
IUUC-Osa-085327	Oryza sativa	31.50	1.00e-25	110.00
IUUC-Ola-086716	Oryzias latipes	40.69	6.00e-75	274.00
IUUC-Olu-087708	Ostreococcus lucimarinus	28.65	1.00e-13	70.50
IUUC-Oar-090239	Ovis aries	57.73	2.00e-120	425.00
IUUC-Ptr-090851	Pan troglodytes	57.29	5.00e-113	400.00
IUUC-Pan-092558	Papio anubis	55.73	4.00e-106	377.00
IUUC-Psi-093792	Pelodiscus sinensis	74.78	1.00e-154	539.00
IUUC-Ppa-095757	Physcomitrella patens	34.08	4.00e-17	82.00
IUUC-Pfo-096465	Poecilia formosa	44.01	6.00e-89	320.00
IUUC-Pab-097722	Pongo abelii	57.59	3.00e-118	418.00
IUUC-Pop-098979	Populus trichocarpa	32.62	2.00e-17	83.20
IUUC-Pca-100753	Procavia capensis	57.66	5.00e-88	317.00
IUUC-Ppe-101515	Prunus persica	29.96	3.00e-20	92.80
IUUC-Sja-107780	Schizosaccharomyces japonicus	27.14	1.00e-12	67.40
IUUC-Spo-108251	Schizosaccharomyces pombe	25.33	1.00e-11	63.90
IUUC-Smo-108938	Selaginella moellendorffii	33.95	3.00e-20	92.40
IUUC-Sit-110020	Setaria italica	31.15	9.00e-23	100.00
IUUC-Sly-111543	Solanum lycopersicum	26.59	8.00e-25	107.00
IUUC-Stu-111925	Solanum tuberosum	25.86	2.00e-23	103.00
IUUC-Sbi-114061	Sorghum bicolor	32.02	1.00e-23	103.00
IUUC-Tgu-117321	Taeniopygia guttata	96.19	0.00e+00	647.00
IUUC-Tru-118454	Takifugu rubripes	45.64	2.00e-85	308.00
IUUC-Tni-119894	Tetraodon nigroviridis	42.20	2.00e-78	285.00
IUUC-Tca-121746	Theobroma cacao	34.01	6.00e-22	98.60
IUUC-Tae-124459	Triticum aestivum	28.72	4.00e-19	89.00
IUUC-Tur-126254	Triticum urartu	25.00	6.00e-11	61.60
IUUC-Tbe-127683	Tupaia belangeri	69.14	7.00e-32	131.00
IUUC-Ttr-129056	Tursiops truncatus	52.88	3.00e-110	391.00
IUUC-Vvi-131428	Vitis vinifera	30.52	1.00e-20	94.40
IUUC-Xma-133605	Xiphophorus maculatus	44.60	1.00e-89	322.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence