iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

   S: 5    eflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqpltee 53
           +f C++ + l  +Pv++p+G+t+  +++e++l++  + cP+++ +l+e 
   Q: 227  DFECALCMRLLFEPVTTPCGHTFCLKCLERCLDHAPH-CPLCKDKLSEL 274
           79***********************************.*******9875 PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           Ca+C+  +++ p+++pCgH+f+++Cl++          + +CPlC+
   Q: 230  CALCMRLLFE-PVTTPCGHTFCLKCLERC------LDHAPHCPLCK 268
           **********.9**************999......9*********7 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MAPDDSSLLL LRAELYLTMK NYEQALQDAD TVCQREPLLT KGHHIKAQIL SGLGRNKEVL 60
KEFIYCLALN PECNSAKKET QKVICEVFFS ASENEQQNSA PSTQTGPKAL CDGQMSPQNP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCGTGCCAG GCGCGGGGAC TACAGCGCCA GCAGCAGCCC GAGGCCGCGC TGCTCAGGTG 60
CCAGCAGGCC CTGGATATGG GTGAGTCAGC CTCGAGGGTG ACCACGGGGC TGGGCGGTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0802--TPR repeat

Interpro

IPR023114--Elongated_TPR_rpt_dom
IPR003111--Lon_substr-bd
IPR015947--PUA-like_domain
IPR013026--TPR-contain_dom
IPR011990--TPR-like_helical_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51787--LON_N
PS50293--TPR_REGION
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF02190--LON_substr_bdg

SMART

SM00464--LON
SM00184--RING

Gene Ontology

GO:0005622--C:intracellular
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001867	Ailuropoda melanoleuca	80.04	0.00e+00	826.00
IUUC-Apl-003355	Anas platyrhynchos	61.09	0.00e+00	649.00
IUUC-Aca-004822	Anolis carolinensis	59.46	0.00e+00	631.00
IUUC-Acl-008224	Aspergillus clavatus	30.50	5.00e-40	159.00
IUUC-Afu-008802	Aspergillus fumigatus	28.70	6.00e-37	149.00
IUUC-Ani-009473	Aspergillus nidulans	29.46	4.00e-41	162.00
IUUC-Cja-019041	Callithrix jacchus	77.61	0.00e+00	800.00
IUUC-Cfa-020025	Canis familiaris	79.84	0.00e+00	804.00
IUUC-Csa-023324	Chlorocebus sabaeus	79.73	0.00e+00	814.00
IUUC-Cne-026875	Cryptococcus neoformans	28.57	4.00e-08	53.50
IUUC-Dre-028400	Danio rerio	49.61	5.00e-144	504.00
IUUC-Dme-031919	Drosophila melanogaster	38.29	2.00e-65	244.00
IUUC-Eeu-034779	Erinaceus europaeus	61.38	2.00e-167	582.00
IUUC-Fca-036276	Felis catus	80.78	0.00e+00	837.00
IUUC-Fal-036669	Ficedula albicollis	61.02	0.00e+00	650.00
IUUC-Fso-038334	Fusarium solani	29.34	6.00e-41	162.00
IUUC-Gmo-039511	Gadus morhua	66.02	1.00e-116	413.00
IUUC-Gga-041253	Gallus gallus	61.67	0.00e+00	649.00
IUUC-Ggo-045501	Gorilla gorilla	80.22	0.00e+00	822.00
IUUC-Hsa-046630	Homo sapiens	80.04	0.00e+00	819.00
IUUC-Itr-048224	Ictidomys tridecemlineatus	78.54	0.00e+00	793.00
IUUC-Laf-054421	Loxodonta africana	60.36	2.00e-169	589.00
IUUC-Mcc-054828	Macaca mulatta	79.34	0.00e+00	810.00
IUUC-Meu-055901	Macropus eugenii	48.07	3.00e-134	472.00
IUUC-Mtr-058075	Medicago truncatula	34.44	3.00e-42	166.00
IUUC-Mga-059760	Meleagris gallopavo	60.53	0.00e+00	652.00
IUUC-Mmr-061350	Microcebus murinus	78.13	0.00e+00	788.00
IUUC-Mdo-062203	Monodelphis domestica	61.73	0.00e+00	659.00
IUUC-Mmu-064118	Mus musculus	92.66	0.00e+00	949.00
IUUC-Mpu-065764	Mustela putorius furo	79.11	0.00e+00	821.00
IUUC-Nfi-068337	Neosartorya fischeri	30.38	1.00e-37	150.00
IUUC-Nle-069616	Nomascus leucogenys	80.22	0.00e+00	822.00
IUUC-Oga-088972	Otolemur garnettii	79.29	0.00e+00	815.00
IUUC-Ptr-090992	Pan troglodytes	80.22	0.00e+00	824.00
IUUC-Pan-092180	Papio anubis	78.92	0.00e+00	808.00
IUUC-Psi-093423	Pelodiscus sinensis	61.57	0.00e+00	654.00
IUUC-Pab-097974	Pongo abelii	80.04	0.00e+00	819.00
IUUC-Pva-102269	Pteropus vampyrus	73.38	0.00e+00	734.00
IUUC-Pgr-103289	Puccinia graminis	26.78	1.00e-28	121.00
IUUC-Spo-108344	Schizosaccharomyces pombe	33.81	2.00e-24	106.00
IUUC-Tgu-117000	Taeniopygia guttata	60.83	0.00e+00	652.00
IUUC-Tru-118016	Takifugu rubripes	49.80	5.00e-143	501.00
IUUC-Tni-119913	Tetraodon nigroviridis	48.31	9.00e-138	483.00
IUUC-Ttr-128666	Tursiops truncatus	74.86	0.00e+00	747.00
IUUC-Uma-129541	Ustilago maydis	35.16	2.00e-35	145.00
IUUC-Vpa-130334	Vicugna pacos	60.48	7.00e-157	547.00
IUUC-Vvi-130910	Vitis vinifera	33.00	5.00e-39	155.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence