iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-033690

UUCD1 version

UUC-EqC-00161

Ensembl Protein ID

ENSECAP00000003143.1

UniProt Accession

F6SAR8; F6SAR8_HORSE

Protein Name

Uncharacterized protein

Gene Name

TOPORS

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000004655.1	ENSECAT00000004538.1	ENSECAP00000003143.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	3.80e-09	37.1	38	77

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C+iCl++f++  ++ +C H f++ C+q w      s++++ CPlC+
   Q: 38   CPICLDRFDNVSYLDRCLHKFCFRCVQEW------SKNKAECPLCK 77
           **********999999*************......**********7 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

QIMASATKEF KMDNFSPKAG TSKLQQTVPA DASPDSKCPI CLDRFDNVSY LDRCLHKFCF 60
RCVQEWSKNK AECPLCKQPF DSIFHSVRAE DDFKEYVLRP SYNGSFATPD VPRFRYRTTM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGATAATGG CATCAGCCAC TAAGGAGTTT AAAATGGACA ACTTTTCGCC TAAAGCTGGC 60
ACTAGCAAAT TGCAACAGAC AGTCCCAGCT GATGCATCTC CTGATTCTAA GTGTCCTATA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

SMART

SM00184--RING

Gene Ontology

GO:0005814--C:centriole
GO:0036064--C:ciliary basal body
GO:0000930--C:gamma-tubulin complex
GO:0016607--C:nuclear speck
GO:0032391--C:photoreceptor connecting cilium
GO:0016605--C:PML body
GO:0000922--C:spindle pole
GO:0000151--C:ubiquitin ligase complex
GO:0003823--F:antigen binding
GO:0003677--F:DNA binding
GO:0019789--F:SUMO transferase activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0042771--P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0051457--P:maintenance of protein location in nucleus
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0051443--P:positive regulation of ubiquitin-protein transferase activity
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0070936--P:protein K48-linked ubiquitination
GO:0006513--P:protein monoubiquitination
GO:0042127--P:regulation of cell proliferation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000940	Aegilops tauschii	36.76	2.00e-09	56.20
IUUC-Aml-002240	Ailuropoda melanoleuca	92.37	0.00e+00	911.00
IUUC-Atr-002964	Amborella trichopoda	33.64	4.00e-13	68.20
IUUC-Apl-003666	Anas platyrhynchos	58.88	1.00e-145	510.00
IUUC-Aca-005305	Anolis carolinensis	61.15	2.00e-149	523.00
IUUC-Aly-005926	Arabidopsis lyrata	32.11	6.00e-11	60.80
IUUC-Ath-007668	Arabidopsis thaliana	22.95	2.00e-10	59.30
IUUC-Ame-011109	Astyanax mexicanus	52.60	5.00e-115	409.00
IUUC-Bta-012637	Bos taurus	91.26	0.00e+00	897.00
IUUC-Bdi-014270	Brachypodium distachyon	40.00	2.00e-11	63.20
IUUC-Bol-015115	Brassica oleracea	29.20	6.00e-09	54.70
IUUC-Bra-017451	Brassica rapa	31.25	2.00e-08	53.10
IUUC-Cja-019105	Callithrix jacchus	93.70	0.00e+00	973.00
IUUC-Cfa-021203	Canis familiaris	92.75	0.00e+00	911.00
IUUC-Cpo-022335	Cavia porcellus	85.74	0.00e+00	847.00
IUUC-Csa-023870	Chlorocebus sabaeus	93.90	0.00e+00	954.00
IUUC-Cho-024870	Choloepus hoffmanni	94.21	0.00e+00	885.00
IUUC-Cne-026788	Cryptococcus neoformans	33.85	3.00e-07	50.40
IUUC-Dre-027535	Danio rerio	50.76	4.00e-119	422.00
IUUC-Dno-028963	Dasypus novemcinctus	93.32	0.00e+00	854.00
IUUC-Dor-030239	Dipodomys ordii	89.98	0.00e+00	795.00
IUUC-Dme-031941	Drosophila melanogaster	47.19	1.00e-19	92.40
IUUC-Ete-032300	Echinops telfairi	84.63	0.00e+00	1123.00
IUUC-Eeu-035257	Erinaceus europaeus	87.93	0.00e+00	861.00
IUUC-Fca-036383	Felis catus	91.82	0.00e+00	903.00
IUUC-Fal-037209	Ficedula albicollis	64.41	2.00e-165	576.00
IUUC-Gmo-039416	Gadus morhua	53.16	6.00e-119	420.00
IUUC-Gga-041267	Gallus gallus	72.33	1.00e-175	610.00
IUUC-Gac-042227	Gasterosteus aculeatus	53.12	7.00e-119	420.00
IUUC-Gma-042777	Glycine max	32.61	6.00e-09	54.70
IUUC-Ggo-044445	Gorilla gorilla	93.71	0.00e+00	972.00
IUUC-Hsa-045844	Homo sapiens	93.90	0.00e+00	974.00
IUUC-Hvu-047531	Hordeum vulgare	46.00	5.00e-11	58.50
IUUC-Itr-048818	Ictidomys tridecemlineatus	92.57	0.00e+00	921.00
IUUC-Lch-050031	Latimeria chalumnae	66.22	1.00e-169	590.00
IUUC-Lpe-051274	Leersia perrieri	37.74	9.00e-09	53.90
IUUC-Loc-052944	Lepisosteus oculatus	58.01	2.00e-142	499.00
IUUC-Laf-053820	Loxodonta africana	94.61	0.00e+00	861.00
IUUC-Mcc-054800	Macaca mulatta	94.10	0.00e+00	956.00
IUUC-Meu-056806	Macropus eugenii	72.23	0.00e+00	643.00
IUUC-Mtr-058378	Medicago truncatula	34.58	2.00e-12	66.20
IUUC-Mla-059017	Melampsora laricipopulina	36.07	3.00e-09	56.20
IUUC-Mvi-060417	Microbotryum violaceum	24.56	6.00e-17	82.80
IUUC-Mmr-061481	Microcebus murinus	94.29	0.00e+00	907.00
IUUC-Mdo-062219	Monodelphis domestica	81.85	2.00e-109	389.00
IUUC-Mmu-064138	Mus musculus	89.35	0.00e+00	814.00
IUUC-Mlu-067088	Myotis lucifugus	93.16	0.00e+00	892.00
IUUC-Nle-069862	Nomascus leucogenys	94.18	0.00e+00	962.00
IUUC-Opr-071076	Ochotona princeps	92.27	0.00e+00	797.00
IUUC-Ont-072225	Oreochromis niloticus	51.02	2.00e-112	400.00
IUUC-Oan-073069	Ornithorhynchus anatinus	66.06	3.00e-159	554.00
IUUC-Ocu-074826	Oryctolagus cuniculus	92.76	0.00e+00	924.00
IUUC-Oba-075429	Oryza barthii	37.68	1.00e-10	60.10
IUUC-Obr-076084	Oryza brachyantha	36.23	3.00e-10	58.50
IUUC-Ogl-077444	Oryza glaberrima	37.68	1.00e-10	60.10
IUUC-Ogu-078603	Oryza glumaepatula	37.68	1.00e-10	60.10
IUUC-Oin-079777	Oryza indica	37.68	1.00e-10	59.70
IUUC-Oni-082396	Oryza nivara	37.68	1.00e-10	60.10
IUUC-Opu-083698	Oryza punctata	36.62	6.00e-10	58.20
IUUC-Oru-084305	Oryza rufipogon	37.68	1.00e-10	60.10
IUUC-Ola-087377	Oryzias latipes	54.86	2.00e-109	389.00
IUUC-Oga-088059	Otolemur garnettii	90.08	0.00e+00	890.00
IUUC-Oar-089592	Ovis aries	91.79	0.00e+00	892.00
IUUC-Ptr-091233	Pan troglodytes	93.71	0.00e+00	972.00
IUUC-Pan-092743	Papio anubis	94.10	0.00e+00	956.00
IUUC-Psi-093669	Pelodiscus sinensis	70.44	0.00e+00	663.00
IUUC-Ppa-095668	Physcomitrella patens	26.98	6.00e-24	105.00
IUUC-Pfo-096706	Poecilia formosa	52.37	5.00e-106	378.00
IUUC-Pop-099119	Populus trichocarpa	24.59	4.00e-12	65.10
IUUC-Pca-100967	Procavia capensis	91.46	0.00e+00	796.00
IUUC-Ppe-101958	Prunus persica	38.96	4.00e-10	58.20
IUUC-Pva-102982	Pteropus vampyrus	96.38	0.00e+00	930.00
IUUC-Pgr-103551	Puccinia graminis	38.46	7.00e-09	54.30
IUUC-Ptt-103977	Puccinia triticina	33.33	5.00e-08	51.20
IUUC-Rno-105730	Rattus norvegicus	87.95	0.00e+00	768.00
IUUC-Sha-106588	Sarcophilus harrisii	70.86	2.00e-180	626.00
IUUC-Sja-107735	Schizosaccharomyces japonicus	35.38	2.00e-07	49.70
IUUC-Smo-109039	Selaginella moellendorffii	24.39	3.00e-18	85.90
IUUC-Sly-111835	Solanum lycopersicum	42.37	1.00e-08	55.80
IUUC-Stu-112898	Solanum tuberosum	42.37	1.00e-08	55.80
IUUC-Sar-113622	Sorex araneus	89.78	3.00e-163	569.00
IUUC-Sre-115041	Sporisorium reilianum	37.84	9.00e-10	57.40
IUUC-Ssc-115244	Sus scrofa	94.86	0.00e+00	868.00
IUUC-Tgu-117180	Taeniopygia guttata	64.99	4.00e-173	601.00
IUUC-Tru-118393	Takifugu rubripes	53.33	1.00e-121	430.00
IUUC-Tsy-119408	Tarsius syrichta	94.02	0.00e+00	927.00
IUUC-Tni-120664	Tetraodon nigroviridis	56.16	4.00e-120	425.00
IUUC-Tca-121712	Theobroma cacao	28.08	2.00e-17	82.80
IUUC-Tae-122787	Triticum aestivum	38.57	1.00e-10	60.50
IUUC-Tbe-127301	Tupaia belangeri	91.51	0.00e+00	803.00
IUUC-Ttr-128204	Tursiops truncatus	94.16	0.00e+00	914.00
IUUC-Uma-129420	Ustilago maydis	43.06	9.00e-10	57.80
IUUC-Vpa-130297	Vicugna pacos	94.52	0.00e+00	914.00
IUUC-Vvi-131157	Vitis vinifera	25.42	4.00e-17	82.00
IUUC-Xtr-132845	Xenopus tropicalis	68.13	1.00e-172	600.00
IUUC-Xma-133439	Xiphophorus maculatus	53.35	3.00e-108	386.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence