iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

mRNA Expression
GEO	FFGED
Protein-protein Interaction
IID	iRefIndex	HINT	Mentha
Post-translational Modifications (PTMs)
CPLM	dbPAF	dbPTM	UniProt
PHOSIDA	BioGRID
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.60e-41	135.0	343	380
UBD/Beta-Prp	3.20e-77	258.1	255	451

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           gH ds ++la+ +d  ++v++s Dg+ikvWD+++g +l
   Q: 343  GHFDSTNSLAYsPDgSRVVTASEDGKIKVWDITSGFCL 380
           79999*******9999******************9987 PP

UBD/Beta-Prp

   S: 5    lkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseD.rtikvwdlstgkcvhtlkghedsvlslsfsp 104
           ++ ++++ ++cv+f+p ++lla+g+++g  +++d+ + +l+++ls  +++v++v+ +++g++l+ gs+  + + v++ ++ +++ + +gh ds  sl++sp
   Q: 255  FFYANQAKVKCVTFHPATRLLAVGFTSGEFRLYDLPDFTLIQQLSMGQNPVNTVSVNQTGEWLAFGSSKlGQLLVYEWQSESYILKQQGHFDSTNSLAYSP 355
           44556667777777777777777777777777777777777777777777777777777777777777777777777777777777777777777777777 PP
   S: 105  sgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsld 201
           +g+++v++s+d  i+vwd+ +g cl  t+++h+++v+ v++ + g++++s+slD+tvr Wdl + +  rt+tg    + ++l++d++g+ + +gsld
   Q: 356  DGSRVVTASEDGKIKVWDITSGFCLA-TFEEHTSSVTAVQFAKRGQVMFSSSLDGTVRAWDLIRYRNFRTFTGTERIQFNCLAVDPSGEVVCAGSLD 451
           77777777777777777777777777.7777777777777777777777777777777777777777777777777777777777777777777777 PP

Organism

Saccharomyces cerevisiae

Functional Description
(View)

Required for bud-site selection and cell separation. Also involved in nucleolar processing of pre-18S ribosomal RNA.

Protein Sequence
(Fasta)

MKSDFKFSNL LGTVYRQGNI TFSDDGKQLL SPVGNRVSVF DLINNKSFTF EYEHRKNIAA 60
IDLNKQGTLL ISIDEDGRAI LVNFKARNVL HHFNFKEKCS AVKFSPDGRL FALASGRFLQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAAATCCG ATTTCAAGTT CTCTAACCTT TTAGGTACGG TCTACAGGCA AGGTAACATC 60
ACCTTTTCCG ATGATGGCAA GCAACTACTC TCACCGGTGG GGAATAGGGT CAGCGTGTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0687--Ribonucleoprotein
KW-0690--Ribosome biogenesis
KW-0698--rRNA processing
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR027145--PWP2
IPR011047--Quinoprotein_ADH-like_supfam
IPR007148--SSU_processome_Utp12
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04003--Utp12
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030686--C:90S preribosome
GO:0005737--C:cytoplasm
GO:0005730--C:nucleolus
GO:0005654--C:nucleoplasm
GO:0034388--C:Pwp2p-containing subcomplex of 90S preribosome
GO:0032040--C:small-subunit processome
GO:0030515--F:snoRNA binding
GO:0000920--P:cell separation after cytokinesis
GO:0000480--P:endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000447--P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000472--P:endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0030010--P:establishment of cell polarity
GO:0000462--P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000028--P:ribosomal small subunit assembly
GO:0031167--P:rRNA methylation

KEGG

sce:YCR057C

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001932	Ailuropoda melanoleuca	43.44	0.00e+00	744.00
IUUC-Atr-003033	Amborella trichopoda	43.54	1.00e-158	551.00
IUUC-Apl-003219	Anas platyrhynchos	43.26	0.00e+00	738.00
IUUC-Aca-004950	Anolis carolinensis	43.21	0.00e+00	742.00
IUUC-Aly-006213	Arabidopsis lyrata	40.44	0.00e+00	658.00
IUUC-Ath-006593	Arabidopsis thaliana	40.11	0.00e+00	659.00
IUUC-Ago-007916	Ashbya gossypii	72.00	0.00e+00	1346.00
IUUC-Acl-008225	Aspergillus clavatus	57.01	0.00e+00	1006.00
IUUC-Afl-008390	Aspergillus flavus	56.73	0.00e+00	1006.00
IUUC-Afu-009039	Aspergillus fumigatus	57.01	0.00e+00	1001.00
IUUC-Ani-009228	Aspergillus nidulans	50.75	0.00e+00	857.00
IUUC-Ang-009663	Aspergillus niger	55.11	0.00e+00	968.00
IUUC-Aor-009923	Aspergillus oryzae	56.73	0.00e+00	1006.00
IUUC-Ate-010264	Aspergillus terreus	56.50	0.00e+00	1009.00
IUUC-Ame-010790	Astyanax mexicanus	32.46	3.00e-55	206.00
IUUC-Bgr-012066	Blumeria graminis	53.09	0.00e+00	982.00
IUUC-Bta-012399	Bos taurus	43.67	0.00e+00	724.00
IUUC-Bci-013757	Botrytis cinerea	56.71	0.00e+00	986.00
IUUC-Bdi-015028	Brachypodium distachyon	41.06	0.00e+00	674.00
IUUC-Bol-016521	Brassica oleracea	39.86	0.00e+00	639.00
IUUC-Bra-017096	Brassica rapa	40.04	0.00e+00	650.00
IUUC-Cel-018690	Caenorhabditis elegans	35.14	8.00e-154	535.00
IUUC-Cja-019229	Callithrix jacchus	43.70	0.00e+00	746.00
IUUC-Cfa-020504	Canis familiaris	43.28	0.00e+00	739.00
IUUC-Cpo-021574	Cavia porcellus	44.22	0.00e+00	763.00
IUUC-Cre-022756	Chlamydomonas reinhardtii	41.79	1.00e-147	515.00
IUUC-Csa-023436	Chlorocebus sabaeus	43.68	0.00e+00	734.00
IUUC-Cin-025397	Ciona intestinalis	43.34	9.00e-169	585.00
IUUC-Csv-026194	Ciona savignyi	46.97	6.00e-139	486.00
IUUC-Cgl-026684	Colletotrichum gloeosporioides	53.21	0.00e+00	961.00
IUUC-Cne-027031	Cryptococcus neoformans	48.41	0.00e+00	900.00
IUUC-Cme-027276	Cyanidioschyzon merolae	30.69	3.00e-77	281.00
IUUC-Dre-027514	Danio rerio	43.36	0.00e+00	716.00
IUUC-Dno-029191	Dasypus novemcinctus	42.03	1.00e-179	621.00
IUUC-Dor-030149	Dipodomys ordii	43.62	0.00e+00	748.00
IUUC-Dse-031260	Dothistroma septosporum	55.12	0.00e+00	649.00
IUUC-Dme-032043	Drosophila melanogaster	39.12	0.00e+00	644.00
IUUC-Ete-033102	Echinops telfairi	52.11	8.00e-155	538.00
IUUC-Eca-033223	Equus caballus	44.17	0.00e+00	755.00
IUUC-Fca-035795	Felis catus	42.18	0.00e+00	691.00
IUUC-Fal-036830	Ficedula albicollis	43.15	0.00e+00	731.00
IUUC-Fox-037835	Fusarium oxysporum	54.02	0.00e+00	953.00
IUUC-Fso-038324	Fusarium solani	56.19	0.00e+00	969.00
IUUC-Gmo-039355	Gadus morhua	43.28	0.00e+00	738.00
IUUC-Ggr-039840	Gaeumannomyces graminis	51.49	0.00e+00	921.00
IUUC-Gga-040907	Gallus gallus	49.24	8.00e-152	528.00
IUUC-Gac-042624	Gasterosteus aculeatus	42.50	0.00e+00	723.00
IUUC-Gma-043034	Glycine max	40.73	0.00e+00	707.00
IUUC-Hsa-046145	Homo sapiens	43.71	0.00e+00	753.00
IUUC-Hvu-047416	Hordeum vulgare	41.52	0.00e+00	685.00
IUUC-Itr-049083	Ictidomys tridecemlineatus	43.44	0.00e+00	765.00
IUUC-Kpa-049150	Komagataella pastoris	65.47	0.00e+00	1167.00
IUUC-Lch-049460	Latimeria chalumnae	42.80	9.00e-180	621.00
IUUC-Lpe-050840	Leersia perrieri	41.84	0.00e+00	697.00
IUUC-Loc-052733	Lepisosteus oculatus	43.28	0.00e+00	735.00
IUUC-Lma-053277	Leptosphaeria maculans	54.62	0.00e+00	984.00
IUUC-Laf-054294	Loxodonta africana	44.53	0.00e+00	736.00
IUUC-Mcc-054624	Macaca mulatta	43.60	0.00e+00	755.00
IUUC-Meu-056665	Macropus eugenii	38.18	2.00e-133	467.00
IUUC-Mor-057288	Magnaporthe oryzae	52.92	0.00e+00	969.00
IUUC-Mpo-057594	Magnaporthe poae	51.32	0.00e+00	916.00
IUUC-Mtr-058700	Medicago truncatula	42.31	0.00e+00	721.00
IUUC-Mla-058846	Melampsora laricipopulina	48.86	0.00e+00	842.00
IUUC-Mga-059207	Meleagris gallopavo	38.92	2.00e-178	617.00
IUUC-Mvi-060327	Microbotryum violaceum	50.75	0.00e+00	895.00
IUUC-Mmr-061264	Microcebus murinus	44.00	0.00e+00	729.00
IUUC-Mdo-062327	Monodelphis domestica	43.98	0.00e+00	752.00
IUUC-Mmu-063542	Mus musculus	44.47	0.00e+00	741.00
IUUC-Mac-065142	Musa acuminata	42.50	0.00e+00	708.00
IUUC-Mpu-066098	Mustela putorius furo	42.01	0.00e+00	625.00
IUUC-Mlu-067056	Myotis lucifugus	39.93	0.00e+00	630.00
IUUC-Nfi-068323	Neosartorya fischeri	56.96	0.00e+00	1007.00
IUUC-Ncr-068925	Neurospora crassa	55.37	0.00e+00	996.00
IUUC-Nle-068970	Nomascus leucogenys	43.49	0.00e+00	749.00
IUUC-Opr-070966	Ochotona princeps	55.02	1.00e-103	368.00
IUUC-Ont-071252	Oreochromis niloticus	42.34	0.00e+00	718.00
IUUC-Oan-072737	Ornithorhynchus anatinus	43.05	0.00e+00	723.00
IUUC-Oba-075794	Oryza barthii	41.53	0.00e+00	671.00
IUUC-Obr-076617	Oryza brachyantha	42.23	0.00e+00	706.00
IUUC-Ogl-077022	Oryza glaberrima	42.52	0.00e+00	709.00
IUUC-Ogu-078757	Oryza glumaepatula	37.52	1.00e-100	358.00
IUUC-Oin-079813	Oryza indica	42.52	0.00e+00	705.00
IUUC-Olo-080265	Oryza longistaminata	42.52	0.00e+00	709.00
IUUC-Ome-081494	Oryza meridionalis	42.30	0.00e+00	704.00
IUUC-Oni-082639	Oryza nivara	37.52	2.00e-100	358.00
IUUC-Opu-084005	Oryza punctata	42.63	0.00e+00	711.00
IUUC-Oru-084883	Oryza rufipogon	37.52	3.00e-100	357.00
IUUC-Osa-086158	Oryza sativa	42.41	0.00e+00	706.00
IUUC-Ola-086822	Oryzias latipes	42.99	0.00e+00	721.00
IUUC-Oga-088887	Otolemur garnettii	43.95	0.00e+00	728.00
IUUC-Oar-090110	Ovis aries	41.83	0.00e+00	676.00
IUUC-Pan-092808	Papio anubis	44.16	0.00e+00	759.00
IUUC-Psi-093954	Pelodiscus sinensis	44.20	0.00e+00	750.00
IUUC-Pno-094922	Phaeosphaeria nodorum	55.56	0.00e+00	1015.00
IUUC-Ppa-095678	Physcomitrella patens	44.99	0.00e+00	687.00
IUUC-Pfo-097175	Poecilia formosa	42.26	0.00e+00	742.00
IUUC-Pab-098155	Pongo abelii	43.64	0.00e+00	755.00
IUUC-Pop-099635	Populus trichocarpa	39.91	0.00e+00	689.00
IUUC-Pca-100947	Procavia capensis	40.98	0.00e+00	682.00
IUUC-Ppe-101552	Prunus persica	43.34	0.00e+00	729.00
IUUC-Pva-102744	Pteropus vampyrus	39.21	7.00e-179	619.00
IUUC-Pgr-103389	Puccinia graminis	49.54	0.00e+00	852.00
IUUC-Ptt-103953	Puccinia triticina	40.85	0.00e+00	657.00
IUUC-Pte-104079	Pyrenophora teres	55.56	0.00e+00	987.00
IUUC-Pyt-104656	Pyrenophora triticirepentis	55.67	0.00e+00	991.00
IUUC-Rno-105502	Rattus norvegicus	44.59	0.00e+00	763.00
IUUC-Sha-107264	Sarcophilus harrisii	41.88	2.00e-90	323.00
IUUC-Sja-107674	Schizosaccharomyces japonicus	51.96	0.00e+00	963.00
IUUC-Spo-108348	Schizosaccharomyces pombe	52.59	0.00e+00	938.00
IUUC-Smo-109327	Selaginella moellendorffii	41.88	0.00e+00	688.00
IUUC-Sit-110304	Setaria italica	42.54	0.00e+00	726.00
IUUC-Sly-111620	Solanum lycopersicum	46.10	1.00e-151	528.00
IUUC-Stu-112877	Solanum tuberosum	42.03	0.00e+00	726.00
IUUC-Sbi-114702	Sorghum bicolor	42.81	0.00e+00	714.00
IUUC-Sre-115129	Sporisorium reilianum	46.07	0.00e+00	800.00
IUUC-Ssc-115931	Sus scrofa	43.41	6.00e-93	332.00
IUUC-Tgu-116787	Taeniopygia guttata	43.15	0.00e+00	734.00
IUUC-Tru-118218	Takifugu rubripes	42.91	0.00e+00	721.00
IUUC-Tsy-119401	Tarsius syrichta	46.30	3.00e-121	427.00
IUUC-Tni-120046	Tetraodon nigroviridis	43.16	0.00e+00	706.00
IUUC-Tca-121685	Theobroma cacao	41.55	0.00e+00	717.00
IUUC-Tre-122154	Trichoderma reesei	55.26	0.00e+00	988.00
IUUC-Tvi-122451	Trichoderma virens	54.19	0.00e+00	983.00
IUUC-Tae-125397	Triticum aestivum	42.74	1.00e-115	409.00
IUUC-Tur-126650	Triticum urartu	41.60	0.00e+00	633.00
IUUC-Tme-127005	Tuber melanosporum	58.57	0.00e+00	1019.00
IUUC-Tbe-128102	Tupaia belangeri	42.94	1.00e-127	448.00
IUUC-Ttr-128259	Tursiops truncatus	44.34	0.00e+00	720.00
IUUC-Uma-129511	Ustilago maydis	46.12	0.00e+00	775.00
IUUC-Vda-129833	Verticillium dahliae	50.47	0.00e+00	884.00
IUUC-Vvi-131572	Vitis vinifera	41.81	0.00e+00	676.00
IUUC-Xtr-131776	Xenopus tropicalis	33.86	2.00e-55	208.00
IUUC-Xma-133887	Xiphophorus maculatus	42.86	0.00e+00	713.00
IUUC-Yli-134427	Yarrowia lipolytica	58.21	0.00e+00	1051.00
IUUC-Zma-135980	Zea mays	42.36	0.00e+00	706.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence