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Tag Content
iUUCD ID IUUC-Laf-053802
Ensembl Protein ID ENSLAFP00000004477.3
UniProt Accession G3SW23; G3SW23_LOXAF
Protein Name Tyrosine-protein kinase
Gene Name ABL2
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSLAFG00000005345.3 ENSLAFT00000005348.3 ENSLAFP00000004477.3
ENSLAFG00000005345.3 ENSLAFT00000021902.2 ENSLAFP00000017461.2
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/SH3 2.70e-12 46.8 109 166
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/SH3
   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
            +++ +lyd+ a+ d++L+++kG++++v+  ++q+++W +     ++ +G +P+n+++ ++
   Q: 109  PNLFVALYDFVASGDNTLSITKGEKLRVL-GYNQNGEWSEV--RSKNGQGWVPSNYITPVN 166
           67899************************.*********98..788899*********997 PP
   
Organism Loxodonta africana
Protein Sequence
(Fasta)
MGQQVSRVEE APGLQQPQPR GIRGSSAARP SDRRREPAGG SAEAGFNIFP QHDHFASCVE 60
DGFEGDKTGG SSPEALHRPY GCDVESQALN EAIRWSSKEN LLGATESDPN LFVALYDFVA 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Laf-053802|UBD,SH3|Loxodonta africana
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGGGGCAGC AGGTGAGCCG CGTCGAGGAG GCTCCGGGTC TCCAGCAGCC GCAGCCCCGC 60
GGGATCCGGG GCAGCAGTGC AGCCAGGCCC TCCGACCGCA GGCGGGAGCC GGCGGGGGGC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Laf-053802|UBD,SH3|Loxodonta africana
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase
Interpro

IPR015015--F-actin_binding
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom
PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3
Pfam

PF08919--F_actin_bind
PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1
PRINTS

PR00401--SH2DOMAIN
PR00109--TYRKINASE
SMART

SM00808--FABD
SM00252--SH2
SM00326--SH3
SM00219--TyrKc
Gene Ontology

GO:0005623--C:cell
GO:0005524--F:ATP binding
GO:0000287--F:magnesium ion binding
GO:0030145--F:manganese ion binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0071300--P:cellular response to retinoic acid
GO:0007204--P:positive regulation of cytosolic calcium ion concentration
GO:0010976--P:positive regulation of neuron projection development
GO:0051353--P:positive regulation of oxidoreductase activity
GO:0010863--P:positive regulation of phospholipase C activity
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002263 Ailuropoda melanoleuca 96.58 0.00e+00 2001.00
IUUC-Apl-003389 Anas platyrhynchos 85.24 0.00e+00 1758.00
IUUC-Ame-010629 Astyanax mexicanus 58.45 0.00e+00 1070.00
IUUC-Bta-013370 Bos taurus 95.44 0.00e+00 2075.00
IUUC-Cja-018894 Callithrix jacchus 94.40 0.00e+00 2007.00
IUUC-Cfa-020398 Canis familiaris 98.90 0.00e+00 1297.00
IUUC-Cpo-022367 Cavia porcellus 94.51 0.00e+00 1536.00
IUUC-Csa-023386 Chlorocebus sabaeus 96.49 0.00e+00 1993.00
IUUC-Cho-024714 Choloepus hoffmanni 91.54 0.00e+00 1889.00
IUUC-Dre-027741 Danio rerio 67.64 0.00e+00 1387.00
IUUC-Dno-029246 Dasypus novemcinctus 93.75 0.00e+00 2014.00
IUUC-Dor-030416 Dipodomys ordii 88.09 0.00e+00 1893.00
IUUC-Ete-032899 Echinops telfairi 77.63 0.00e+00 858.00
IUUC-Eca-033387 Equus caballus 96.91 0.00e+00 2013.00
IUUC-Eeu-035058 Erinaceus europaeus 84.56 0.00e+00 1872.00
IUUC-Fca-036578 Felis catus 89.56 0.00e+00 1810.00
IUUC-Fal-037491 Ficedula albicollis 87.88 0.00e+00 1879.00
IUUC-Gmo-038509 Gadus morhua 77.23 0.00e+00 1131.00
IUUC-Gga-040638 Gallus gallus 85.71 0.00e+00 1834.00
IUUC-Gac-042550 Gasterosteus aculeatus 67.29 0.00e+00 1325.00
IUUC-Ggo-044487 Gorilla gorilla 95.78 0.00e+00 2085.00
IUUC-Hsa-046636 Homo sapiens 95.86 0.00e+00 2085.00
IUUC-Itr-048685 Ictidomys tridecemlineatus 96.02 0.00e+00 2030.00
IUUC-Lch-049530 Latimeria chalumnae 76.55 0.00e+00 1589.00
IUUC-Loc-051933 Lepisosteus oculatus 70.00 0.00e+00 1444.00
IUUC-Mcc-054836 Macaca mulatta 95.86 0.00e+00 2106.00
IUUC-Mga-059277 Meleagris gallopavo 88.05 0.00e+00 1850.00
IUUC-Mmr-061206 Microcebus murinus 94.76 0.00e+00 2024.00
IUUC-Mdo-062281 Monodelphis domestica 92.60 0.00e+00 1244.00
IUUC-Mmu-063847 Mus musculus 94.01 0.00e+00 1967.00
IUUC-Mac-065156 Musa acuminata 27.72 2.00e-22 100.00
IUUC-Mpu-066309 Mustela putorius furo 97.24 0.00e+00 1378.00
IUUC-Mlu-068070 Myotis lucifugus 96.13 0.00e+00 1991.00
IUUC-Nle-070062 Nomascus leucogenys 97.10 0.00e+00 1334.00
IUUC-Opr-070534 Ochotona princeps 90.60 0.00e+00 1068.00
IUUC-Ont-072440 Oreochromis niloticus 67.87 0.00e+00 1239.00
IUUC-Oan-073526 Ornithorhynchus anatinus 88.22 0.00e+00 1769.00
IUUC-Ocu-074051 Oryctolagus cuniculus 94.78 0.00e+00 1889.00
IUUC-Olo-080286 Oryza longistaminata 34.84 1.00e-23 105.00
IUUC-Opu-083538 Oryza punctata 35.29 2.00e-23 104.00
IUUC-Oru-084741 Oryza rufipogon 34.84 9.00e-24 105.00
IUUC-Osa-085779 Oryza sativa 34.84 1.00e-23 105.00
IUUC-Ola-086752 Oryzias latipes 95.04 0.00e+00 914.00
IUUC-Oga-088767 Otolemur garnettii 90.31 0.00e+00 1797.00
IUUC-Oar-089800 Ovis aries 96.13 0.00e+00 1986.00
IUUC-Ptr-090857 Pan troglodytes 97.10 0.00e+00 1333.00
IUUC-Pan-092279 Papio anubis 94.09 0.00e+00 2021.00
IUUC-Psi-093573 Pelodiscus sinensis 88.53 0.00e+00 1823.00
IUUC-Pfo-096543 Poecilia formosa 61.69 0.00e+00 1253.00
IUUC-Pab-097949 Pongo abelii 94.09 0.00e+00 1986.00
IUUC-Pca-100370 Procavia capensis 95.25 0.00e+00 1482.00
IUUC-Pva-103220 Pteropus vampyrus 87.93 0.00e+00 1801.00
IUUC-Rno-105924 Rattus norvegicus 90.37 0.00e+00 1918.00
IUUC-Sha-107114 Sarcophilus harrisii 88.90 0.00e+00 1397.00
IUUC-Ssc-115968 Sus scrofa 95.02 0.00e+00 2143.00
IUUC-Tgu-117301 Taeniopygia guttata 87.35 0.00e+00 1792.00
IUUC-Tru-118410 Takifugu rubripes 65.95 0.00e+00 1395.00
IUUC-Tni-119991 Tetraodon nigroviridis 66.08 0.00e+00 1402.00
IUUC-Tca-121389 Theobroma cacao 33.33 3.00e-23 103.00
IUUC-Tae-125058 Triticum aestivum 31.98 6.00e-20 93.20
IUUC-Tbe-127362 Tupaia belangeri 90.88 0.00e+00 1878.00
IUUC-Ttr-129291 Tursiops truncatus 95.95 0.00e+00 1993.00
IUUC-Vpa-130800 Vicugna pacos 95.42 0.00e+00 1549.00
IUUC-Vvi-131057 Vitis vinifera 30.35 6.00e-22 99.80
IUUC-Xtr-132965 Xenopus tropicalis 67.72 0.00e+00 1443.00
Created Date 25-Jun-2017

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