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Tag Content
UUCD2 ID IUUC-Pab-098539
UUCD1 version UUC-PoA-01069
Ensembl Protein ID ENSPPYP00000018877.2
UniProt Accession H2PJV8; H2PJV8_PONAB
Genbank Protein ID ENSPPYP00000018877
Protein Name Ubiquitinyl hydrolase 1
Genbank Nucleotide ID ABGA01204070
Gene Name USP45
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSPPYG00000016864.2 ENSPPYT00000019623.2 ENSPPYP00000018877.2
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/USP 6.20e-86 288.7 191 813
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/USP
   S: 2    GlkNlgNtCYmNSvLQcLsnipelrellle..kkkeklneenp..............kepkgellkslqklfeelwkskkkavsprell 74
           G++NlgNtC++N+v+Q L+++  l++l++e  +  ++++ +                 ++ g+l+++l  +++++ +++k+  sp+ l+
   Q: 191  GITNLGNTCFFNAVMQNLAQTYTLTDLMNEikE--SSTKLK-IfpssdsqldplvveLSRPGPLTSALFLFLHSMKETEKGPLSPKVLF 276
           9*****************************542..333222.23445566666777777777*************************** PP
   S: 75   kalkkeaeefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde......aeekkkkknkslisdlFqgqlksqikcl 157
           ++l+++a++f+ ++qqD+qE+l++lld++++e +k+ + ++ +++++ ++++ d+      + + k+  + ++i+++F g+l+s+++c+
   Q: 277  NQLCQKAPRFKDFQQQDSQELLHYLLDAVRTEETKRIQASILKAFNNPTTKTADDetrkkvKAYGKEGVKMNFIDRIFIGELTSTVMCE 365
           *********************************99888888888888877777773443335555555555****************** PP
   S: 158  ecdnvssreepfldlslpvpgkeetkke............................................................. 185
           ec+n+s+ ++pf+d+slp+ +++ +k++                                                             
   Q: 366  ECANISTVKDPFIDISLPIIEERVSKPLlsgrmnkyrslretdhdrysgnvtienihqpraakkhssskdksqlihdrkcirklssget 454
           ***********************99888************************************************************* PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 455  vvtyqknenlemngdslmfaslmnsesrlnesptddsekeashsesnvdadsepsesesaskqtglfrsssgssvhpdgplyrlsagel 543
           ***************************************************************************************** PP
   S: 186  ............................................................................slqdcLesftkee 198
                                                                                       s+q+cL +ft+ e
   Q: 544  lytketdsgdkemaeaiselrlsstvtgdqdfdrenqplnisnnlcflegkhlrshspqnafqtlsqsyittskecSIQSCLYQFTSME 632
           ***************************************************************************************** PP
   S: 199  elegenkyycekckkkqe...................aekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctsp 268
            l g+nk+ ce+c+k+++                   a+k+l ++ +P vLilhLkRf  ++++ s +k+n++v+fpl+Ldl+pfc+ +
   Q: 633  LLMGNNKLLCENCTKNKQkyqeetsfaekkvegvytnARKQLLISAVPAVLILHLKRF--HQAGLSLRKVNRHVDFPLMLDLAPFCSAT 719
           **************88888999999999999999999*********************..9999************************8 PP
   S: 269  eekqke..kkkYeLiavvvHsGslssGHYvayvkn..........................ekgkWllfdDskVtevkeeevleetgst 329
           +++ +   k+ Y L+++v HsGs+++GHY+ayvk                           + g+W++++D++V++v+e++ l+   ++
   Q: 720  CKNASMgdKVLYGLYGIVEHSGSMREGHYTAYVKVrtpsrklsehntkkknvpglkeadseSAGQWVHVSDTYVQVVPESRALS---AQ 805
           877655669**************************999999999999999999998888777888*******************...** PP
   S: 330  aYvlfYkr 337
           aY+lfY+r
   Q: 806  AYLLFYER 813
           ******98 PP
   
Organism Pongo abelii
Protein Sequence
(Fasta)
MRVKDPTKAL PEKAKRSKRP TVPRDEDSSD DIAVGLTCQH VSHAISVNHV KRAIAENLWS 60
VCSECLKERR VYDGQLVLTS DIWLCLKCGF QGCGKNSESQ HSLKHFKSSR TEPHCIIINL 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Pab-098539|DUB,USP|Pongo abelii
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CCCTCAGTCC CTTCAGTAAA TAACAGATGC GGGTGAAAGA TCCAACTAAA GCTTTACCTG 60
AGAAAGCCAA AAGAAGTAAA AGGCCTACTG TACCTCGTGA TGAAGACTCT TCAGATGATA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Pab-098539|DUB,USP|Pongo abelii
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP
PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP
Pfam

PF00443--UCH
PF02148--zf-UBP
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0006281--P:DNA repair
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002331 Ailuropoda melanoleuca 73.75 0.00e+00 1098.00
IUUC-Atr-003015 Amborella trichopoda 28.40 3.00e-31 130.00
IUUC-Apl-003512 Anas platyrhynchos 67.31 0.00e+00 1053.00
IUUC-Aca-004284 Anolis carolinensis 61.00 0.00e+00 943.00
IUUC-Aly-006422 Arabidopsis lyrata 29.81 3.00e-27 117.00
IUUC-Ath-006732 Arabidopsis thaliana 28.97 6.00e-31 129.00
IUUC-Ame-010735 Astyanax mexicanus 64.26 1.00e-86 313.00
IUUC-Bta-012880 Bos taurus 81.54 0.00e+00 1259.00
IUUC-Bol-015941 Brassica oleracea 28.34 1.00e-26 115.00
IUUC-Bra-016751 Brassica rapa 29.23 1.00e-26 115.00
IUUC-Cja-019144 Callithrix jacchus 92.88 0.00e+00 1505.00
IUUC-Cfa-020971 Canis familiaris 82.63 0.00e+00 724.00
IUUC-Cpo-022497 Cavia porcellus 69.27 0.00e+00 1070.00
IUUC-Csa-023910 Chlorocebus sabaeus 94.30 0.00e+00 1439.00
IUUC-Cho-024358 Choloepus hoffmanni 61.90 7.00e-110 390.00
IUUC-Dre-028106 Danio rerio 61.65 3.00e-152 532.00
IUUC-Dno-029456 Dasypus novemcinctus 77.12 0.00e+00 710.00
IUUC-Dor-030438 Dipodomys ordii 64.06 0.00e+00 936.00
IUUC-Dme-031870 Drosophila melanogaster 46.71 6.00e-36 146.00
IUUC-Ete-032736 Echinops telfairi 64.72 0.00e+00 931.00
IUUC-Eca-034211 Equus caballus 83.03 0.00e+00 1332.00
IUUC-Eeu-034797 Erinaceus europaeus 81.01 2.00e-85 309.00
IUUC-Fca-035947 Felis catus 77.89 0.00e+00 1143.00
IUUC-Fal-037199 Ficedula albicollis 66.89 0.00e+00 924.00
IUUC-Gmo-039228 Gadus morhua 61.52 3.00e-142 499.00
IUUC-Gga-040823 Gallus gallus 63.85 1.00e-164 572.00
IUUC-Gac-042406 Gasterosteus aculeatus 59.76 6.00e-138 484.00
IUUC-Gma-044402 Glycine max 27.34 2.00e-30 128.00
IUUC-Ggo-045402 Gorilla gorilla 98.41 0.00e+00 1602.00
IUUC-Hsa-046430 Homo sapiens 98.16 0.00e+00 1602.00
IUUC-Itr-048855 Ictidomys tridecemlineatus 82.05 0.00e+00 757.00
IUUC-Lch-049547 Latimeria chalumnae 57.89 0.00e+00 898.00
IUUC-Loc-052842 Lepisosteus oculatus 58.75 0.00e+00 896.00
IUUC-Laf-053988 Loxodonta africana 83.41 0.00e+00 1343.00
IUUC-Mcc-055491 Macaca mulatta 89.58 0.00e+00 1440.00
IUUC-Meu-056256 Macropus eugenii 64.51 3.00e-175 608.00
IUUC-Mtr-057945 Medicago truncatula 31.17 2.00e-33 137.00
IUUC-Mla-059026 Melampsora laricipopulina 31.22 1.00e-16 81.60
IUUC-Mga-059833 Meleagris gallopavo 60.14 5.00e-167 580.00
IUUC-Mmr-060952 Microcebus murinus 85.31 0.00e+00 1342.00
IUUC-Mdo-062642 Monodelphis domestica 70.37 0.00e+00 1079.00
IUUC-Mmu-063945 Mus musculus 77.51 0.00e+00 1210.00
IUUC-Mpu-065944 Mustela putorius furo 75.43 0.00e+00 1163.00
IUUC-Mlu-067049 Myotis lucifugus 81.71 0.00e+00 1259.00
IUUC-Nle-069828 Nomascus leucogenys 97.06 0.00e+00 1585.00
IUUC-Opr-070672 Ochotona princeps 69.92 5.00e-140 491.00
IUUC-Ont-072121 Oreochromis niloticus 59.27 7.00e-136 478.00
IUUC-Oan-073656 Ornithorhynchus anatinus 64.66 0.00e+00 1025.00
IUUC-Ocu-074323 Oryctolagus cuniculus 81.17 0.00e+00 1257.00
IUUC-Ola-087238 Oryzias latipes 59.90 1.00e-148 520.00
IUUC-Oga-088379 Otolemur garnettii 77.60 0.00e+00 1225.00
IUUC-Oar-089718 Ovis aries 81.66 0.00e+00 1258.00
IUUC-Ptr-091358 Pan troglodytes 98.28 0.00e+00 1603.00
IUUC-Pan-092023 Papio anubis 95.22 0.00e+00 1539.00
IUUC-Psi-093256 Pelodiscus sinensis 65.70 0.00e+00 972.00
IUUC-Ppa-095622 Physcomitrella patens 29.37 1.00e-29 125.00
IUUC-Pfo-097285 Poecilia formosa 52.17 4.00e-121 429.00
IUUC-Pop-099588 Populus trichocarpa 32.40 1.00e-33 139.00
IUUC-Pca-100610 Procavia capensis 67.63 0.00e+00 915.00
IUUC-Ppe-101794 Prunus persica 28.48 3.00e-29 124.00
IUUC-Pva-102985 Pteropus vampyrus 89.19 0.00e+00 684.00
IUUC-Rno-105538 Rattus norvegicus 77.02 0.00e+00 1212.00
IUUC-Sha-107022 Sarcophilus harrisii 72.62 4.00e-179 621.00
IUUC-Sja-107712 Schizosaccharomyces japonicus 27.51 9.00e-21 95.50
IUUC-Spo-108149 Schizosaccharomyces pombe 30.66 2.00e-20 94.40
IUUC-Sly-111491 Solanum lycopersicum 30.75 4.00e-32 133.00
IUUC-Stu-112820 Solanum tuberosum 29.32 1.00e-34 142.00
IUUC-Sar-113637 Sorex araneus 70.29 0.00e+00 1058.00
IUUC-Ssc-115870 Sus scrofa 81.66 0.00e+00 1307.00
IUUC-Tgu-116907 Taeniopygia guttata 67.48 0.00e+00 1060.00
IUUC-Tru-117835 Takifugu rubripes 51.96 4.00e-110 392.00
IUUC-Tsy-118869 Tarsius syrichta 78.92 0.00e+00 1228.00
IUUC-Tni-120015 Tetraodon nigroviridis 36.09 3.00e-135 476.00
IUUC-Tca-121701 Theobroma cacao 30.56 1.00e-33 139.00
IUUC-Tbe-128041 Tupaia belangeri 66.14 0.00e+00 952.00
IUUC-Ttr-128901 Tursiops truncatus 81.30 0.00e+00 1275.00
IUUC-Vpa-130331 Vicugna pacos 83.09 0.00e+00 1195.00
IUUC-Xtr-131794 Xenopus tropicalis 52.42 0.00e+00 774.00
Created Date 25-Jun-2017

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