iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-117562

UUCD1 version

UUC-TaR-00038

Ensembl Protein ID

ENSTRUP00000001547.1

UniProt Accession

H2RN34; H2RN34_TAKRU

Protein Name

Uncharacterized protein

Gene Name

SOCS7

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000000648.1	ENSTRUT00000001555.1	ENSTRUP00000001547.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	6.40e-14	52.8	409	455

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 3    klwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyedy 52
           ++ +++s++ SLqhLCR++Ir++++++++   ++LPLP  L++YL+++ y
   Q: 409  YPVSRFSSVKSLQHLCRFCIRQLVRIDHI---QELPLPTPLISYLRKFYY 455
           67899*********************998...**************9976 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

GEDPTETSDA LLVLEGLGSG EGGEDEEGGS SEKGPQTGRG GGGLHRSELP LTSGHIRRCH 60
VPPPVCGLSP PHQSTCSPPQ LQQPPPFFKC PHPSRPPRGK SRKGGSLKVR LSKLFRTKSS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGTGAGGACC CAACTGAGAC CAGCGATGCC CTTCTTGTTC TGGAAGGTCT TGGTTCTGGG 60
GAGGGGGGAG AAGATGAAGA AGGAGGGAGC AGTGAAAAAG GTGAGACACC GGGGGACGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR028423--SOCS7
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF07525--SOCS_box

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005737--C:cytoplasm
GO:0004860--F:protein kinase inhibitor activity
GO:0019221--P:cytokine-mediated signaling pathway
GO:0035556--P:intracellular signal transduction
GO:0046426--P:negative regulation of JAK-STAT cascade
GO:0006469--P:negative regulation of protein kinase activity
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001668	Ailuropoda melanoleuca	61.30	4.00e-106	378.00
IUUC-Apl-003277	Anas platyrhynchos	85.23	1.00e-65	241.00
IUUC-Aca-004639	Anolis carolinensis	87.36	1.00e-91	328.00
IUUC-Ame-011301	Astyanax mexicanus	68.75	2.00e-112	399.00
IUUC-Bta-013483	Bos taurus	61.38	4.00e-107	381.00
IUUC-Cel-018643	Caenorhabditis elegans	31.85	2.00e-10	58.50
IUUC-Cja-019765	Callithrix jacchus	67.11	2.00e-102	365.00
IUUC-Cfa-020109	Canis familiaris	61.66	9.00e-107	380.00
IUUC-Cpo-021555	Cavia porcellus	61.72	1.00e-105	377.00
IUUC-Csa-023580	Chlorocebus sabaeus	60.46	5.00e-107	381.00
IUUC-Cho-024431	Choloepus hoffmanni	83.61	5.00e-56	211.00
IUUC-Cin-025413	Ciona intestinalis	46.20	2.00e-40	159.00
IUUC-Csv-026247	Ciona savignyi	42.99	1.00e-41	164.00
IUUC-Dre-028183	Danio rerio	87.00	2.00e-103	370.00
IUUC-Dno-028858	Dasypus novemcinctus	61.34	3.00e-106	379.00
IUUC-Dor-031071	Dipodomys ordii	47.37	1.00e-55	209.00
IUUC-Dme-031876	Drosophila melanogaster	43.23	2.00e-39	157.00
IUUC-Ete-032928	Echinops telfairi	93.10	2.00e-44	173.00
IUUC-Eca-033250	Equus caballus	58.21	9.00e-103	366.00
IUUC-Eeu-034946	Erinaceus europaeus	71.43	6.00e-30	125.00
IUUC-Fca-036589	Felis catus	61.98	2.00e-106	379.00
IUUC-Fal-037316	Ficedula albicollis	85.50	8.00e-97	346.00
IUUC-Gmo-038552	Gadus morhua	99.03	5.00e-58	215.00
IUUC-Gga-041248	Gallus gallus	86.34	2.00e-91	327.00
IUUC-Gac-041469	Gasterosteus aculeatus	85.83	7.00e-62	228.00
IUUC-Ggo-045282	Gorilla gorilla	65.11	1.00e-102	365.00
IUUC-Hsa-045926	Homo sapiens	60.46	4.00e-107	382.00
IUUC-Itr-048411	Ictidomys tridecemlineatus	56.30	8.00e-70	257.00
IUUC-Lch-049768	Latimeria chalumnae	62.28	9.00e-104	370.00
IUUC-Loc-051949	Lepisosteus oculatus	85.02	2.00e-103	369.00
IUUC-Laf-053410	Loxodonta africana	61.66	9.00e-107	380.00
IUUC-Mcc-054605	Macaca mulatta	67.11	4.00e-102	365.00
IUUC-Meu-056773	Macropus eugenii	79.53	5.00e-56	211.00
IUUC-Mga-059273	Meleagris gallopavo	51.76	3.00e-34	139.00
IUUC-Mmr-060927	Microcebus murinus	61.56	1.00e-106	380.00
IUUC-Mdo-061892	Monodelphis domestica	61.60	6.00e-108	384.00
IUUC-Mmu-064246	Mus musculus	61.58	9.00e-107	380.00
IUUC-Mpu-065995	Mustela putorius furo	60.94	1.00e-106	379.00
IUUC-Mlu-067526	Myotis lucifugus	63.73	7.00e-108	384.00
IUUC-Nle-069317	Nomascus leucogenys	62.28	2.00e-93	335.00
IUUC-Opr-070873	Ochotona princeps	53.53	3.00e-43	169.00
IUUC-Ont-072275	Oreochromis niloticus	70.55	7.00e-140	490.00
IUUC-Oan-073703	Ornithorhynchus anatinus	75.58	3.00e-34	135.00
IUUC-Ocu-074577	Oryctolagus cuniculus	60.78	3.00e-105	375.00
IUUC-Ola-086866	Oryzias latipes	50.59	1.00e-32	132.00
IUUC-Oga-088426	Otolemur garnettii	63.80	1.00e-106	380.00
IUUC-Oar-089407	Ovis aries	61.38	8.00e-108	384.00
IUUC-Ptr-091327	Pan troglodytes	60.68	2.00e-106	379.00
IUUC-Pan-092064	Papio anubis	61.26	6.00e-106	377.00
IUUC-Psi-093834	Pelodiscus sinensis	64.92	2.00e-101	361.00
IUUC-Pma-094253	Petromyzon marinus	52.69	2.00e-41	164.00
IUUC-Pfo-097100	Poecilia formosa	60.45	2.00e-106	380.00
IUUC-Pab-097695	Pongo abelii	60.53	2.00e-105	376.00
IUUC-Pca-100569	Procavia capensis	59.21	9.00e-101	360.00
IUUC-Pva-102784	Pteropus vampyrus	61.98	3.00e-107	382.00
IUUC-Rno-105485	Rattus norvegicus	61.58	1.00e-106	380.00
IUUC-Sha-106720	Sarcophilus harrisii	64.18	2.00e-107	382.00
IUUC-Sar-112975	Sorex araneus	54.61	7.00e-74	270.00
IUUC-Ssc-116369	Sus scrofa	61.07	1.00e-106	380.00
IUUC-Tgu-116867	Taeniopygia guttata	87.11	4.00e-97	347.00
IUUC-Tsy-118999	Tarsius syrichta	64.14	2.00e-85	308.00
IUUC-Tni-120793	Tetraodon nigroviridis	63.41	1.00e-113	403.00
IUUC-Tbe-127671	Tupaia belangeri	83.41	1.00e-100	360.00
IUUC-Ttr-128491	Tursiops truncatus	81.95	5.00e-61	228.00
IUUC-Vpa-130104	Vicugna pacos	62.40	9.00e-105	374.00
IUUC-Xtr-132507	Xenopus tropicalis	89.62	2.00e-96	346.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence