iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Itr-048560

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTP01046276

Gene Name

POC1A

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000002638.2	ENSSTOT00000002632.2	ENSSTOP00000002354.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.40e-59	194.1	181	218
UBD/Beta-Prp	4.80e-72	242.6	95	310

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           H + vt ++f ++ t +++++ D+t+kvWD+rt++ll+
   Q: 181  HGSFVTYVDFhPSgTCIAAAGMDNTVKVWDVRTHRLLQ 218
           88889******666*********************998 PP

UBD/Beta-Prp

   S: 49   sgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghd 137
             h+a+v++v f +dg+ lvt+s+D+t+kvw+      + +l++h + v++ +fsp+g  +vs+s+d+t+++wd  +++c++    +h 
   Q: 95   RAHSATVRSVHFCSDGQSLVTASDDKTVKVWSTHRQRFLFSLNQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKTSRECVY-SYCEHG 182
           78********************************************************************************.999*** PP
   S: 138  gvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvk 226
           ++v++v +hp+g ++++++ D+tv++Wd++t +ll++ +  h  +v+ lsf+++g++l+++s d+t+k+ dl +g+ ++tl+gh+ + +
   Q: 183  SFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQL-HSAAVNALSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPAT 270
           **************************************98.************************************************ PP
   S: 227  svrfspnderlvsgssDgsiriW..dlrsgdllktlqlhn 264
            v+fs+ +e+++sg+sD+++ +W  + ++ d+  +++ ++
   Q: 271  TVAFSRTGEYFASGGSDEQVMVWksNFDNVDYGEVIKVQR 310
           ***********************99666666666555555 PP

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

QEDPSLERHF KGHRDAVTCV DFSVNMKQLA SGSMDSCLMI WHMKPQSRAY RFTGHKDAIT 60
CVNFSPSGHL LASGSRDKTV RIWVPNVKGE STMFRAHSAT VRSVHFCSDG QSLVTASDDK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGGAGGACC CCTCACTGGA GAGGCATTTT AAGGGCCACC GAGATGCAGT TACCTGTGTG 60
GACTTCAGCG TCAACATGAA GCAGCTGGGT AACAGAAGGC ATCTTGTCCC AGGCACTAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005814--C:centriole
GO:0036064--C:ciliary basal body
GO:0000922--C:spindle pole
GO:0003431--P:growth plate cartilage chondrocyte development
GO:0007052--P:mitotic spindle organization
GO:1905515--P:non-motile cilium assembly
GO:0010825--P:positive regulation of centrosome duplication
GO:0007283--P:spermatogenesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001513	Ailuropoda melanoleuca	92.79	0.00e+00	757.00
IUUC-Apl-003466	Anas platyrhynchos	77.25	0.00e+00	646.00
IUUC-Aca-004323	Anolis carolinensis	71.00	4.00e-180	623.00
IUUC-Bta-012484	Bos taurus	91.02	0.00e+00	773.00
IUUC-Cja-019067	Callithrix jacchus	91.60	0.00e+00	780.00
IUUC-Cfa-020439	Canis familiaris	92.52	0.00e+00	778.00
IUUC-Cpo-021403	Cavia porcellus	92.04	0.00e+00	782.00
IUUC-Cre-022724	Chlamydomonas reinhardtii	50.13	4.00e-112	397.00
IUUC-Csa-023479	Chlorocebus sabaeus	93.50	0.00e+00	699.00
IUUC-Cho-024354	Choloepus hoffmanni	84.55	2.00e-112	397.00
IUUC-Cin-025258	Ciona intestinalis	72.52	1.00e-141	496.00
IUUC-Csv-025955	Ciona savignyi	63.06	1.00e-145	509.00
IUUC-Dno-029467	Dasypus novemcinctus	77.94	1.00e-124	438.00
IUUC-Dor-030399	Dipodomys ordii	90.30	0.00e+00	764.00
IUUC-Dme-032182	Drosophila melanogaster	46.33	1.00e-80	293.00
IUUC-Eca-034425	Equus caballus	94.03	0.00e+00	763.00
IUUC-Eeu-034607	Erinaceus europaeus	79.80	0.00e+00	637.00
IUUC-Fca-035627	Felis catus	93.77	0.00e+00	767.00
IUUC-Fal-037381	Ficedula albicollis	74.38	0.00e+00	631.00
IUUC-Gmo-038489	Gadus morhua	67.84	9.00e-162	562.00
IUUC-Gga-040559	Gallus gallus	73.37	3.00e-177	613.00
IUUC-Gac-041453	Gasterosteus aculeatus	69.33	2.00e-171	595.00
IUUC-Ggo-044773	Gorilla gorilla	92.77	0.00e+00	756.00
IUUC-Hsa-045823	Homo sapiens	93.27	0.00e+00	762.00
IUUC-Lch-050558	Latimeria chalumnae	69.07	4.00e-178	617.00
IUUC-Loc-052836	Lepisosteus oculatus	68.59	3.00e-177	614.00
IUUC-Laf-053974	Loxodonta africana	83.42	0.00e+00	673.00
IUUC-Mcc-055494	Macaca mulatta	91.65	0.00e+00	753.00
IUUC-Meu-056646	Macropus eugenii	75.00	1.00e-128	452.00
IUUC-Mga-059295	Meleagris gallopavo	68.10	1.00e-171	595.00
IUUC-Mmr-061040	Microcebus murinus	94.01	0.00e+00	793.00
IUUC-Mdo-062519	Monodelphis domestica	77.84	2.00e-177	614.00
IUUC-Mmu-063759	Mus musculus	94.00	2.00e-172	598.00
IUUC-Mpu-066442	Mustela putorius furo	92.52	0.00e+00	759.00
IUUC-Mlu-068163	Myotis lucifugus	90.52	0.00e+00	759.00
IUUC-Nle-070160	Nomascus leucogenys	93.52	0.00e+00	764.00
IUUC-Opr-070192	Ochotona princeps	90.32	0.00e+00	677.00
IUUC-Ont-072539	Oreochromis niloticus	71.56	2.00e-150	525.00
IUUC-Ocu-074624	Oryctolagus cuniculus	91.33	0.00e+00	714.00
IUUC-Ola-087268	Oryzias latipes	62.88	9.00e-160	556.00
IUUC-Oga-088964	Otolemur garnettii	87.16	0.00e+00	743.00
IUUC-Oar-090202	Ovis aries	91.29	0.00e+00	746.00
IUUC-Ptr-091164	Pan troglodytes	93.03	0.00e+00	763.00
IUUC-Pan-092805	Papio anubis	92.95	0.00e+00	697.00
IUUC-Psi-093359	Pelodiscus sinensis	81.93	5.00e-164	570.00
IUUC-Pma-094425	Petromyzon marinus	76.77	3.00e-152	531.00
IUUC-Ppa-095677	Physcomitrella patens	45.25	2.00e-81	295.00
IUUC-Pfo-096741	Poecilia formosa	57.68	5.00e-153	533.00
IUUC-Pab-098376	Pongo abelii	93.27	0.00e+00	797.00
IUUC-Pca-101122	Procavia capensis	88.53	0.00e+00	745.00
IUUC-Pva-103104	Pteropus vampyrus	72.82	8.00e-168	582.00
IUUC-Rno-105282	Rattus norvegicus	87.30	0.00e+00	666.00
IUUC-Sha-106840	Sarcophilus harrisii	79.17	5.00e-117	412.00
IUUC-Smo-108731	Selaginella moellendorffii	44.63	4.00e-78	284.00
IUUC-Sar-113262	Sorex araneus	63.09	1.00e-141	495.00
IUUC-Ssc-115392	Sus scrofa	92.15	0.00e+00	657.00
IUUC-Tgu-117340	Taeniopygia guttata	73.50	3.00e-177	614.00
IUUC-Tru-117577	Takifugu rubripes	71.91	3.00e-136	478.00
IUUC-Tsy-119404	Tarsius syrichta	85.54	0.00e+00	721.00
IUUC-Tni-120713	Tetraodon nigroviridis	70.78	1.00e-137	483.00
IUUC-Tbe-127788	Tupaia belangeri	72.58	1.00e-156	545.00
IUUC-Ttr-128608	Tursiops truncatus	88.28	0.00e+00	707.00
IUUC-Xtr-132720	Xenopus tropicalis	62.56	5.00e-159	553.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence