iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Gga-040365

UUCD1 version

UUC-GaG-00829

Ensembl Protein ID

ENSGALP00000050643.1

UniProt Accession

A0A1D5PD02; A0A1D5PD02_CHICK

Genbank Protein ID

ENSGALP00000050643

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AADN04000419

Gene Name

UBA7

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGALG00000036263.1	ENSGALT00000070275.1	ENSGALP00000050643.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	9.10e-148	493.2	396	854

Active Site

Position(s)	Description	Evidence
577	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGv.....gsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkel 84
           YD+Qi+++G++ qe l+++k+++vGag++GcEllKn++++G+     g itv+Dmdt+  snl rq Lfr+ dvgk+KAevaa+a++ +
   Q: 396  YDGQIAVFGADFQEELGRQKYFVVGAGAIGCELLKNFAMMGLaagpgGDITVTDMDTIARSNLHRQLLFREADVGKPKAEVAAAAVRLI 484
           ***************************************************************************************** PP
   S: 85   npdvnveaheesiteleeeiv...FfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqkt 170
           npd++v+ah+ ++ + +e+ +   Ff+++d+ v+ald + ar ++ + c+  r  l+++gt+G +G+v  +++ l    +   dp + +
   Q: 485  NPDIKVTAHQAQLGPGTEKLFgstFFRRLDGAVSALDTLTARAYLESCCIRSRTALLDTGTEGAKGNVLAMVPPLSQQLEPGSDPADGS 573
           *******************99***********************************************999999998777777****** PP
   S: 171  iPfctlketpnaaehtiewa............vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafak 247
           +P+ctl+ +p a+eht++wa            + +      +++  e  e+l + e + + ++v+++l+ e+++++ +++++a+++++ 
   Q: 574  FPLCTLRFFPCAIEHTLQWArdefeglfqlpaESV------NRFLGELPEELPRWEGLVVPEQVRRSLQ-ERPRDWGDCVRWARRHWQL 655
           *********************99987554444333......4555666677788888889999966655.57***************** PP
   S: 248  ttinsikqllksfecdivtkskspfwv.............................................................s 275
           +++nsi qll++ ++   ++ ++pfw+                                                             +
   Q: 656  RYHNSIAQLLHDVPPSHESSPGVPFWSgdrrcphpltfdisndthlayveaaahllahtyrlpscgdrvatrdvlchtvlppfvpkdgR 744
           ***************************************************99999999999999999999999999976665555555 PP
   S: 276  fcsnaealqvpekvekdeevvkasaplylllralerfekkkg...rkpgelsfekdddsavdlvtaaanlraeslgiepkldddlikei 361
           +++ +e +++ e ++++ +       l  l++ l r++++ g   + ++ + ++kddd +++++taa+nlrae+++i+p +d+   ++i
   Q: 745  YVPTVEGVEEVEEALEPGQ-------LLELVQELARWKQELGggtEAMDPIHYDKDDDLHLSFITAASNLRAENYSIPP-ADRLTSQRI 825
           5555555555555555555.......677888888888875422278899*****************************.********* PP
   S: 362  agniipaiattnavvgGlaaqEviKvvsg 390
           ag+i+pai tt+a+v++la++Ev+K+v  
   Q: 826  AGRIVPAIITTTAAVAALACLEVYKLVWR 854
           **************************977 PP

Organism

Gallus gallus

Protein Sequence
(Fasta)

MAGARYSRQL LVLGGGGRRL REAAVLVGGL RGVGAQAAAA LVLAGARRVV LHESGAAPGG 60
VQFLQGERGV GRNRAEVSQQ LLAALNPDVE VSVHPGELSE EFLAAFQVVL LTESPLEEQL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGGCG CGCGCTACTC CCGGCAGCTG TGCGTGCGGG GCCGCGGGCG GCGGGGTCCG 60
AGCGGCCGCC TTCCTGCCGC TGAGCGCCCG CCGTGCCCCG CAGGTTGGTG CTGGGCGGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0436--Ligase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR032420--E1_4HB
IPR032418--E1_FCCH
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR018965--Ub-activating_enz_E1_C
IPR019572--UBA_E1_Cys
IPR018075--UBQ-activ_enz_E1
IPR033127--UBQ-activ_enz_E1_Cys_AS
IPR000011--UBQ/SUMO-activ_enz_E1-like

PROSITE

PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF16191--E1_4HB
PF16190--E1_FCCH
PF09358--E1_UFD
PF00899--ThiF
PF10585--UBA_e1_thiolCys

PRINTS

PR01849--UBIQUITINACT

SMART

SM00985--UBA_e1_C

Gene Ontology

GO:0005524--F:ATP binding
GO:0008641--F:small protein activating enzyme activity
GO:0006464--P:cellular protein modification process

KEGG

gga:395178

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001311	Ailuropoda melanoleuca	47.52	0.00e+00	824.00
IUUC-Aca-004746	Anolis carolinensis	49.06	0.00e+00	862.00
IUUC-Ame-010933	Astyanax mexicanus	45.89	0.00e+00	761.00
IUUC-Bta-012767	Bos taurus	47.36	0.00e+00	836.00
IUUC-Cja-019152	Callithrix jacchus	47.36	0.00e+00	835.00
IUUC-Cfa-020622	Canis familiaris	46.76	0.00e+00	803.00
IUUC-Cpo-022526	Cavia porcellus	47.26	0.00e+00	819.00
IUUC-Csa-023780	Chlorocebus sabaeus	47.26	0.00e+00	834.00
IUUC-Dre-028149	Danio rerio	47.00	0.00e+00	808.00
IUUC-Dno-028884	Dasypus novemcinctus	46.57	0.00e+00	820.00
IUUC-Dor-030229	Dipodomys ordii	45.16	0.00e+00	785.00
IUUC-Ete-033124	Echinops telfairi	49.78	2.00e-164	573.00
IUUC-Eca-033330	Equus caballus	47.26	0.00e+00	833.00
IUUC-Eeu-034717	Erinaceus europaeus	45.32	2.00e-157	549.00
IUUC-Fca-036255	Felis catus	47.66	0.00e+00	831.00
IUUC-Fal-037445	Ficedula albicollis	65.71	0.00e+00	1164.00
IUUC-Gmo-039338	Gadus morhua	44.58	0.00e+00	768.00
IUUC-Gac-041773	Gasterosteus aculeatus	44.37	0.00e+00	758.00
IUUC-Ggo-045336	Gorilla gorilla	47.36	0.00e+00	818.00
IUUC-Hsa-045982	Homo sapiens	47.26	0.00e+00	815.00
IUUC-Itr-048460	Ictidomys tridecemlineatus	47.36	0.00e+00	836.00
IUUC-Lch-050371	Latimeria chalumnae	47.63	0.00e+00	842.00
IUUC-Loc-052936	Lepisosteus oculatus	48.21	0.00e+00	827.00
IUUC-Laf-053948	Loxodonta africana	48.53	0.00e+00	822.00
IUUC-Mcc-055843	Macaca mulatta	47.06	0.00e+00	831.00
IUUC-Meu-056258	Macropus eugenii	46.37	0.00e+00	804.00
IUUC-Mga-060052	Meleagris gallopavo	90.38	0.00e+00	1400.00
IUUC-Mmr-061405	Microcebus murinus	46.05	0.00e+00	795.00
IUUC-Mdo-062032	Monodelphis domestica	46.58	0.00e+00	795.00
IUUC-Mmu-063280	Mus musculus	46.87	0.00e+00	811.00
IUUC-Mpu-066409	Mustela putorius furo	47.76	0.00e+00	842.00
IUUC-Mlu-067217	Myotis lucifugus	46.57	0.00e+00	816.00
IUUC-Nle-070072	Nomascus leucogenys	47.46	0.00e+00	793.00
IUUC-Opr-070715	Ochotona princeps	43.48	0.00e+00	686.00
IUUC-Ont-071671	Oreochromis niloticus	45.37	0.00e+00	794.00
IUUC-Oan-073306	Ornithorhynchus anatinus	47.38	6.00e-178	617.00
IUUC-Ocu-074544	Oryctolagus cuniculus	47.46	0.00e+00	837.00
IUUC-Ola-087002	Oryzias latipes	45.64	0.00e+00	799.00
IUUC-Oga-088594	Otolemur garnettii	47.27	0.00e+00	817.00
IUUC-Oar-090068	Ovis aries	47.47	0.00e+00	834.00
IUUC-Ptr-090581	Pan troglodytes	45.69	0.00e+00	705.00
IUUC-Pan-092114	Papio anubis	47.16	0.00e+00	832.00
IUUC-Pfo-097184	Poecilia formosa	44.87	0.00e+00	793.00
IUUC-Pab-097861	Pongo abelii	47.06	0.00e+00	801.00
IUUC-Pca-100347	Procavia capensis	46.00	0.00e+00	705.00
IUUC-Pva-102584	Pteropus vampyrus	47.56	0.00e+00	856.00
IUUC-Rno-105462	Rattus norvegicus	47.16	0.00e+00	817.00
IUUC-Sha-107142	Sarcophilus harrisii	48.00	0.00e+00	814.00
IUUC-Sar-113737	Sorex araneus	46.67	0.00e+00	830.00
IUUC-Ssc-115777	Sus scrofa	47.77	0.00e+00	835.00
IUUC-Tru-118742	Takifugu rubripes	45.22	0.00e+00	773.00
IUUC-Tni-120401	Tetraodon nigroviridis	45.01	0.00e+00	775.00
IUUC-Tbe-127587	Tupaia belangeri	51.70	1.00e-178	620.00
IUUC-Ttr-128331	Tursiops truncatus	47.16	0.00e+00	822.00
IUUC-Xtr-132026	Xenopus tropicalis	40.65	1.00e-170	593.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence