iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-118742

UUCD1 version

UUC-TaR-01070

Ensembl Protein ID

ENSTRUP00000026383.1

UniProt Accession

H2TNX7; H2TNX7_TAKRU

Protein Name

Uncharacterized protein

Gene Name

uba1; LOC101077094

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000010472.1	ENSTRUT00000026486.1	ENSTRUP00000026379.1
ENSTRUG00000010472.1	ENSTRUT00000026487.1	ENSTRUP00000026380.1
ENSTRUG00000010472.1	ENSTRUT00000026488.1	ENSTRUP00000026381.1
ENSTRUG00000010472.1	ENSTRUT00000026489.1	ENSTRUP00000026382.1
ENSTRUG00000010472.1	ENSTRUT00000026490.1	ENSTRUP00000026383.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	4.20e-216	719.1	452	930

Active Site

Position(s)	Description	Evidence
632	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGv....gsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkeln 85
           YD+Qi+++G + qe l +++++lvGag++GcEl Kn++++G+    g++ v+Dmdt+e+snlnrqFLfr++dv k K+++aa a+k++n
   Q: 452  YDGQIAVFGKNMQETLAKQRYFLVGAGAIGCELMKNFAMIGLaageGEVIVTDMDTIEKSNLNRQFLFRPSDVTKMKSDTAAMAVKQMN 540
           ***************************************************************************************** PP
   S: 86   pdvnveaheesiteleeeiv...FfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqkti 171
           p++++++h++++ +++e+++   Ff+ +d+V +aldn++ar++++r+c+++r+pl+esgtlG++G+v+v+i+ lte+ys+s+dpp+k+i
   Q: 541  PSMKITPHQNRVGPDTERVYdddFFESLDGVTNALDNVDARMYMDRRCVYYRKPLLESGTLGTKGNVQVVIPFLTESYSSSQDPPEKSI 629
           *******************9********************************************************************* PP
   S: 172  Pfctlketpnaaehtiewa............vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafakt 248
           P+ctlk++pna+eht++wa            +   ++l +++++ e++ kl  +++ e++++v ++l++  + ++++++++a+++++ +
   Q: 630  PICTLKNFPNAIEHTLQWArdefeglfkqppENSMQYL-TDPKFMERTLKLPGAQPVEVLEAVYKSLVTDCPHSWADCVAWARNHWQCQ 717
           ******************************99999999.78888899999*************************************** PP
   S: 249  tinsikqllksfecdivtkskspfwv.......................................................sfcsnaea 282
           ++n+i+qll++f++d++t+s++pfw+                                                         +    +
   Q: 718  YNNNIRQLLHNFPPDQLTSSGAPFWSgpkrcphplefstsnelhmdyvvaaanlfaqtygvqgstdragvikilqdvkvpvFTPRSGVK 806
           ************************************99999999999999999999999999988888877777776666433333344 PP
   S: 283  lqvpekvekdeevvkasaplylllralerfekkkgrkpgelsfekddds..avdlvtaaanlraeslgiepkldddlikeiagniipai 369
           + v +  +++ +++ +++ l+ l++ l + e+ + +    ++fekddd   ++d++ a +nlrae+++i+p  d+++ k iag+iipai
   Q: 807  IHVSDQELQNSHASVDDSRLEELKTQLPSPESSQFK-LCAIDFEKDDDTnfHMDFIVASSNLRAENYDIPP-TDRHKSKLIAGKIIPAI 893
           445555555555554554589999999988877766.559*******************************.***************** PP
   S: 370  attnavvgGlaaqEviKvvsg..kfeplknfflfdae 404
           att+a+v Gl+++E++K+++g  k e +kn f+++a+
   Q: 894  ATTTAAVVGLVCLELFKIIQGhkKLESYKNGFMNLAL 930
           *********************99999******99875 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

MSSSPLSKKR RLSGTETKTG SHCSSSNSVK TDLSHTPANG MAKNGNDAEI DEGLYSRQLY 60
VLGHDAMKRM QNSNVLISGM RGLGVEIAKN VILGGVKSVT VHDQGVAEWR DLSSQFYLRE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAACTCACAC GGAGCCCGCC ACCCTGACAC ACTTTCCAGT GTGCAGTTAA CGGCACTGTT 60
GAGTTATCTT CTCACTTGTT AGGTTTTCGG CTTTTAAACA ATCCGATTTT AACACTACAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0436--Ligase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR032420--E1_4HB
IPR032418--E1_FCCH
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR018965--Ub-activating_enz_E1_C
IPR019572--UBA_E1_Cys
IPR018075--UBQ-activ_enz_E1
IPR033127--UBQ-activ_enz_E1_Cys_AS
IPR000011--UBQ/SUMO-activ_enz_E1-like

PROSITE

PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF16191--E1_4HB
PF16190--E1_FCCH
PF09358--E1_UFD
PF00899--ThiF
PF10585--UBA_e1_thiolCys

PRINTS

PR01849--UBIQUITINACT

SMART

SM00985--UBA_e1_C

Gene Ontology

GO:0005524--F:ATP binding
GO:0008641--F:small protein activating enzyme activity
GO:0007409--P:axonogenesis
GO:0006464--P:cellular protein modification process

KEGG

tru:101070345

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000456	Aegilops tauschii	46.16	0.00e+00	878.00
IUUC-Aml-001311	Ailuropoda melanoleuca	76.11	0.00e+00	1688.00
IUUC-Atr-002684	Amborella trichopoda	44.08	0.00e+00	864.00
IUUC-Aca-004620	Anolis carolinensis	77.97	0.00e+00	1694.00
IUUC-Aly-005515	Arabidopsis lyrata	44.93	0.00e+00	902.00
IUUC-Ath-006891	Arabidopsis thaliana	45.29	0.00e+00	904.00
IUUC-Ago-007873	Ashbya gossypii	52.51	0.00e+00	1010.00
IUUC-Acl-008181	Aspergillus clavatus	55.03	0.00e+00	1050.00
IUUC-Afl-008455	Aspergillus flavus	53.74	0.00e+00	1011.00
IUUC-Afu-009065	Aspergillus fumigatus	55.13	0.00e+00	1074.00
IUUC-Ani-009371	Aspergillus nidulans	53.91	0.00e+00	1028.00
IUUC-Ang-009737	Aspergillus niger	55.00	0.00e+00	1058.00
IUUC-Aor-010007	Aspergillus oryzae	53.74	0.00e+00	1011.00
IUUC-Ate-010466	Aspergillus terreus	53.97	0.00e+00	1067.00
IUUC-Ame-010933	Astyanax mexicanus	88.19	0.00e+00	1842.00
IUUC-Bgr-012281	Blumeria graminis	53.08	0.00e+00	1046.00
IUUC-Bta-012767	Bos taurus	77.90	0.00e+00	1718.00
IUUC-Bci-013721	Botrytis cinerea	55.75	0.00e+00	1022.00
IUUC-Bdi-014335	Brachypodium distachyon	44.85	0.00e+00	876.00
IUUC-Bol-015665	Brassica oleracea	45.20	0.00e+00	890.00
IUUC-Bra-017522	Brassica rapa	46.05	0.00e+00	871.00
IUUC-Cel-018260	Caenorhabditis elegans	48.38	0.00e+00	946.00
IUUC-Cja-019152	Callithrix jacchus	77.34	0.00e+00	1703.00
IUUC-Cfa-020622	Canis familiaris	75.73	0.00e+00	1638.00
IUUC-Cpo-022526	Cavia porcellus	76.86	0.00e+00	1694.00
IUUC-Cre-022702	Chlamydomonas reinhardtii	45.74	0.00e+00	867.00
IUUC-Csa-023780	Chlorocebus sabaeus	77.53	0.00e+00	1711.00
IUUC-Cin-025790	Ciona intestinalis	62.73	0.00e+00	1325.00
IUUC-Csv-026084	Ciona savignyi	59.83	0.00e+00	1311.00
IUUC-Cgl-026512	Colletotrichum gloeosporioides	54.20	0.00e+00	1075.00
IUUC-Cne-026960	Cryptococcus neoformans	57.38	0.00e+00	1110.00
IUUC-Cme-027290	Cyanidioschyzon merolae	44.66	0.00e+00	818.00
IUUC-Dre-028149	Danio rerio	86.67	0.00e+00	1852.00
IUUC-Dno-028884	Dasypus novemcinctus	77.34	0.00e+00	1707.00
IUUC-Dor-030229	Dipodomys ordii	74.22	0.00e+00	1627.00
IUUC-Dse-031524	Dothistroma septosporum	53.71	0.00e+00	1038.00
IUUC-Dme-032045	Drosophila melanogaster	59.86	0.00e+00	1269.00
IUUC-Ete-032544	Echinops telfairi	65.02	0.00e+00	677.00
IUUC-Eca-033330	Equus caballus	77.24	0.00e+00	1710.00
IUUC-Eeu-034717	Erinaceus europaeus	42.25	3.00e-161	562.00
IUUC-Fca-036255	Felis catus	77.53	0.00e+00	1703.00
IUUC-Fal-037445	Ficedula albicollis	47.28	0.00e+00	851.00
IUUC-Fox-038007	Fusarium oxysporum	54.70	3.00e-164	571.00
IUUC-Fso-038339	Fusarium solani	54.54	0.00e+00	1030.00
IUUC-Gmo-039338	Gadus morhua	84.98	0.00e+00	1790.00
IUUC-Ggr-039823	Gaeumannomyces graminis	54.53	0.00e+00	1097.00
IUUC-Gga-040365	Gallus gallus	45.79	0.00e+00	775.00
IUUC-Gac-041773	Gasterosteus aculeatus	88.79	0.00e+00	1876.00
IUUC-Gma-043198	Glycine max	44.47	0.00e+00	857.00
IUUC-Ggo-045336	Gorilla gorilla	77.24	0.00e+00	1697.00
IUUC-Hsa-045982	Homo sapiens	77.05	0.00e+00	1690.00
IUUC-Hvu-047418	Hordeum vulgare	45.54	0.00e+00	870.00
IUUC-Itr-048460	Ictidomys tridecemlineatus	77.62	0.00e+00	1717.00
IUUC-Kpa-049112	Komagataella pastoris	51.27	0.00e+00	992.00
IUUC-Lch-050371	Latimeria chalumnae	82.44	0.00e+00	1796.00
IUUC-Lpe-051299	Leersia perrieri	43.89	0.00e+00	856.00
IUUC-Loc-052936	Lepisosteus oculatus	86.40	0.00e+00	1852.00
IUUC-Lma-053315	Leptosphaeria maculans	54.85	0.00e+00	1095.00
IUUC-Laf-053948	Loxodonta africana	75.92	0.00e+00	1652.00
IUUC-Mcc-055843	Macaca mulatta	77.53	0.00e+00	1712.00
IUUC-Meu-056258	Macropus eugenii	77.05	0.00e+00	1675.00
IUUC-Mor-057269	Magnaporthe oryzae	55.31	0.00e+00	1078.00
IUUC-Mpo-057435	Magnaporthe poae	55.26	0.00e+00	1081.00
IUUC-Mtr-058572	Medicago truncatula	44.75	0.00e+00	837.00
IUUC-Mla-059176	Melampsora laricipopulina	55.94	0.00e+00	1073.00
IUUC-Mvi-060437	Microbotryum violaceum	54.22	0.00e+00	1060.00
IUUC-Mmr-061405	Microcebus murinus	75.35	0.00e+00	1651.00
IUUC-Mdo-062032	Monodelphis domestica	75.94	0.00e+00	1653.00
IUUC-Mmu-063280	Mus musculus	76.96	0.00e+00	1689.00
IUUC-Mac-065505	Musa acuminata	45.72	0.00e+00	871.00
IUUC-Mpu-066409	Mustela putorius furo	76.96	0.00e+00	1707.00
IUUC-Mlu-067217	Myotis lucifugus	76.96	0.00e+00	1692.00
IUUC-Nfi-068407	Neosartorya fischeri	55.03	0.00e+00	1055.00
IUUC-Ncr-068698	Neurospora crassa	54.91	0.00e+00	1084.00
IUUC-Nle-070072	Nomascus leucogenys	73.44	0.00e+00	1584.00
IUUC-Opr-070715	Ochotona princeps	41.25	0.00e+00	734.00
IUUC-Ont-071671	Oreochromis niloticus	91.76	0.00e+00	1943.00
IUUC-Oan-073306	Ornithorhynchus anatinus	46.93	0.00e+00	703.00
IUUC-Ocu-074544	Oryctolagus cuniculus	78.19	0.00e+00	1724.00
IUUC-Oba-075120	Oryza barthii	44.63	0.00e+00	849.00
IUUC-Obr-076557	Oryza brachyantha	45.62	0.00e+00	842.00
IUUC-Ogl-077887	Oryza glaberrima	44.72	0.00e+00	852.00
IUUC-Ogu-078305	Oryza glumaepatula	43.65	0.00e+00	848.00
IUUC-Oin-079370	Oryza indica	43.61	0.00e+00	832.00
IUUC-Olo-081089	Oryza longistaminata	43.56	0.00e+00	847.00
IUUC-Ome-081942	Oryza meridionalis	44.42	0.00e+00	846.00
IUUC-Oni-082365	Oryza nivara	44.62	0.00e+00	850.00
IUUC-Opu-083977	Oryza punctata	44.53	0.00e+00	851.00
IUUC-Oru-084469	Oryza rufipogon	43.65	0.00e+00	851.00
IUUC-Osa-085949	Oryza sativa	44.63	0.00e+00	857.00
IUUC-Ola-087002	Oryzias latipes	89.37	0.00e+00	1910.00
IUUC-Olu-087687	Ostreococcus lucimarinus	44.65	0.00e+00	809.00
IUUC-Oga-088594	Otolemur garnettii	76.98	0.00e+00	1688.00
IUUC-Oar-090068	Ovis aries	77.64	0.00e+00	1712.00
IUUC-Ptr-090581	Pan troglodytes	43.99	0.00e+00	739.00
IUUC-Pan-092114	Papio anubis	77.62	0.00e+00	1715.00
IUUC-Pma-094214	Petromyzon marinus	58.29	3.00e-52	197.00
IUUC-Pno-095154	Phaeosphaeria nodorum	54.17	0.00e+00	1086.00
IUUC-Ppa-095227	Physcomitrella patens	44.71	0.00e+00	870.00
IUUC-Pfo-097184	Poecilia formosa	90.13	0.00e+00	1919.00
IUUC-Pab-097861	Pongo abelii	77.05	0.00e+00	1681.00
IUUC-Pop-098934	Populus trichocarpa	43.90	0.00e+00	891.00
IUUC-Pca-100347	Procavia capensis	74.19	0.00e+00	1347.00
IUUC-Ppe-102012	Prunus persica	44.56	0.00e+00	868.00
IUUC-Pva-102584	Pteropus vampyrus	77.53	0.00e+00	1734.00
IUUC-Pgr-103336	Puccinia graminis	54.70	0.00e+00	1055.00
IUUC-Ptt-103939	Puccinia triticina	54.12	0.00e+00	1044.00
IUUC-Pte-104200	Pyrenophora teres	52.87	0.00e+00	1082.00
IUUC-Pyt-104441	Pyrenophora triticirepentis	53.15	0.00e+00	1075.00
IUUC-Rno-105462	Rattus norvegicus	77.05	0.00e+00	1681.00
IUUC-Sce-106245	Saccharomyces cerevisiae	51.03	0.00e+00	1023.00
IUUC-Sha-107142	Sarcophilus harrisii	77.43	0.00e+00	1697.00
IUUC-Sja-107841	Schizosaccharomyces japonicus	54.62	0.00e+00	1093.00
IUUC-Spo-108034	Schizosaccharomyces pombe	53.96	0.00e+00	1048.00
IUUC-Ssl-108497	Sclerotinia sclerotiorum	55.65	0.00e+00	1044.00
IUUC-Smo-109211	Selaginella moellendorffii	44.91	0.00e+00	873.00
IUUC-Sit-110281	Setaria italica	45.79	0.00e+00	876.00
IUUC-Sly-110914	Solanum lycopersicum	44.51	0.00e+00	872.00
IUUC-Stu-112109	Solanum tuberosum	44.22	0.00e+00	873.00
IUUC-Sar-113737	Sorex araneus	77.15	0.00e+00	1698.00
IUUC-Sbi-114089	Sorghum bicolor	45.49	0.00e+00	875.00
IUUC-Sre-115148	Sporisorium reilianum	54.39	0.00e+00	1049.00
IUUC-Ssc-115777	Sus scrofa	77.45	0.00e+00	1709.00
IUUC-Tni-120401	Tetraodon nigroviridis	95.79	0.00e+00	1975.00
IUUC-Tca-121672	Theobroma cacao	44.96	0.00e+00	877.00
IUUC-Tre-122009	Trichoderma reesei	52.89	0.00e+00	1012.00
IUUC-Tvi-122259	Trichoderma virens	53.87	0.00e+00	1009.00
IUUC-Tae-125113	Triticum aestivum	46.25	0.00e+00	852.00
IUUC-Tur-126330	Triticum urartu	46.26	0.00e+00	880.00
IUUC-Tme-127055	Tuber melanosporum	52.94	0.00e+00	973.00
IUUC-Tbe-127487	Tupaia belangeri	72.44	0.00e+00	805.00
IUUC-Ttr-128331	Tursiops truncatus	76.96	0.00e+00	1684.00
IUUC-Uma-129387	Ustilago maydis	54.72	0.00e+00	1043.00
IUUC-Vda-129977	Verticillium dahliae	53.61	0.00e+00	989.00
IUUC-Vvi-130857	Vitis vinifera	44.13	0.00e+00	862.00
IUUC-Xtr-132026	Xenopus tropicalis	64.59	0.00e+00	1258.00
IUUC-Xma-133805	Xiphophorus maculatus	90.13	0.00e+00	1918.00
IUUC-Yli-134547	Yarrowia lipolytica	53.06	0.00e+00	1075.00
IUUC-Zma-135052	Zea mays	45.74	0.00e+00	880.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence