iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-003589

Ensembl Protein ID

ENSAPLP00000010352.1

UniProt Accession

U3ISX9; U3ISX9_ANAPL

Genbank Protein ID

ENSAPLP00000010352

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADON01034254

Gene Name

HECTD2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000010621.1	ENSAPLT00000011065.1	ENSAPLP00000010352.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	1.80e-102	342.9	393	731

Active Site

Position(s)	Description	Evidence
699	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldl 90
           ++dlkk+l+v+fvgE+gld+gG+t+e++ ll++++++pd+g+f+y+++++++++ + +      ++ + F+++G l+g+a++++  ld+
   Q: 393  RADLKKKLKVTFVGEAGLDMGGLTKEWFLLLIRQIFHPDYGMFTYHKDSRCHWFSSFKC-----DNYSEFRLVGALMGLAVYNSITLDI 476
           589***************************************************87766.....789********************** PP
   S: 91   plsksfyklllgk..............klsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipV 165
           ++++++yk+ll+               +++l+dl +++pel++ l+e++++ e ++ee  +  tf+v +e++g +k+++Lkp+G++ipV
   Q: 477  RFPPCCYKKLLSPpivpcdhntlvgicDVTLDDLFQIMPELAHGLNELLSY-EGNVEED-FYSTFQVFQEEFGVIKSYNLKPNGDKIPV 563
           ***********99666666666666666**********************9.6788885.***************************** PP
   S: 166  tneNkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevle 254
           tn+N++eYv+l+v++ l+++i +q++af+ Gf++v+    l l+++ee+e+l+cG++e+d+++l++ t+y+ gy++++ +i++Fw+v+ 
   Q: 564  TNQNRKEYVQLYVDFLLNKSIYKQFAAFYYGFHSVCASYALLLLRPEEVEILVCGSPELDMSALQRSTQYE-GYQKTDLTIRYFWDVVL 651
           **********************************************************************5.5**************** PP
   S: 255  efsseerkafLqFvTgssrlPlgGfaelkprlfvirk.dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFels 336
           +fs + +k++L+F+Tgs+r+P+gG+a+l+   f i+k ++s+++lP ++TCfn+L+LP+Y++k++lk+kL++ i++++gF+l+
   Q: 652  GFSLDLQKKLLHFATGSDRVPVGGMADLN---FKISKsETSTNWLPVAHTCFNQLCLPPYKNKKELKQKLIIGISNAEGFGLE 731
           *****************************...9999967777**************************************985 PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

GLERGAKNQF STFSNFITTI NQKKEGTGNS NSPTQLVIPN IKNEVRDLPP ICLDVRQKQR 60
ISIDTLPQEL KAPIPPEPSL PIRTKTVKDF QDDIEKSKSS GDWKAVHDFY STTFDSFLEI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGTTGGAAA GAGGAGCGAA AAATCAGTTT TCTACTTTCA GCAATTTCAT CACAACTATC 60
AACCAAAAGA AAGAAGGCAC CGGAAACAGC AATTCACCTA CGCAACTTGT TATACCTAAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001266	Ailuropoda melanoleuca	86.67	0.00e+00	1339.00
IUUC-Aca-004350	Anolis carolinensis	84.13	0.00e+00	1262.00
IUUC-Ago-007908	Ashbya gossypii	34.53	2.00e-81	296.00
IUUC-Acl-008288	Aspergillus clavatus	34.54	1.00e-93	338.00
IUUC-Afl-008402	Aspergillus flavus	33.17	8.00e-87	314.00
IUUC-Afu-008762	Aspergillus fumigatus	33.33	1.00e-90	328.00
IUUC-Ani-009176	Aspergillus nidulans	34.72	7.00e-90	325.00
IUUC-Ang-009791	Aspergillus niger	34.58	5.00e-90	325.00
IUUC-Aor-009921	Aspergillus oryzae	33.00	9.00e-86	311.00
IUUC-Ate-010295	Aspergillus terreus	35.16	2.00e-97	350.00
IUUC-Ame-010660	Astyanax mexicanus	82.94	1.00e-152	531.00
IUUC-Bgr-011981	Blumeria graminis	40.22	3.00e-91	329.00
IUUC-Bta-012945	Bos taurus	86.05	0.00e+00	1303.00
IUUC-Bci-013697	Botrytis cinerea	39.42	1.00e-79	291.00
IUUC-Cja-019263	Callithrix jacchus	84.35	0.00e+00	1277.00
IUUC-Cfa-020486	Canis familiaris	89.15	0.00e+00	1219.00
IUUC-Cpo-021755	Cavia porcellus	85.66	0.00e+00	1310.00
IUUC-Csa-023814	Chlorocebus sabaeus	84.68	0.00e+00	1216.00
IUUC-Cho-024980	Choloepus hoffmanni	70.59	0.00e+00	1030.00
IUUC-Cgl-026526	Colletotrichum gloeosporioides	40.88	2.00e-94	340.00
IUUC-Dre-028551	Danio rerio	76.99	0.00e+00	1158.00
IUUC-Dno-029497	Dasypus novemcinctus	85.36	0.00e+00	1197.00
IUUC-Dor-030867	Dipodomys ordii	74.11	0.00e+00	1086.00
IUUC-Dse-031239	Dothistroma septosporum	31.59	4.00e-88	319.00
IUUC-Ete-032902	Echinops telfairi	72.37	0.00e+00	1079.00
IUUC-Eca-033678	Equus caballus	85.77	0.00e+00	1310.00
IUUC-Eeu-035262	Erinaceus europaeus	72.16	0.00e+00	995.00
IUUC-Fca-035590	Felis catus	86.59	0.00e+00	1339.00
IUUC-Fal-037123	Ficedula albicollis	93.48	0.00e+00	1385.00
IUUC-Fox-037941	Fusarium oxysporum	40.19	2.00e-99	357.00
IUUC-Fso-038388	Fusarium solani	41.07	1.00e-101	364.00
IUUC-Gmo-039553	Gadus morhua	66.93	0.00e+00	855.00
IUUC-Ggr-040110	Gaeumannomyces graminis	39.48	2.00e-95	343.00
IUUC-Gga-040406	Gallus gallus	97.13	0.00e+00	1483.00
IUUC-Gac-042141	Gasterosteus aculeatus	77.25	0.00e+00	1130.00
IUUC-Ggo-045504	Gorilla gorilla	84.35	0.00e+00	1281.00
IUUC-Hsa-045786	Homo sapiens	84.95	0.00e+00	1288.00
IUUC-Itr-048050	Ictidomys tridecemlineatus	81.69	0.00e+00	1153.00
IUUC-Kpa-049152	Komagataella pastoris	33.08	6.00e-75	275.00
IUUC-Lch-049824	Latimeria chalumnae	81.50	0.00e+00	1120.00
IUUC-Loc-052173	Lepisosteus oculatus	80.16	0.00e+00	1203.00
IUUC-Laf-054017	Loxodonta africana	88.06	0.00e+00	1270.00
IUUC-Mcc-055713	Macaca mulatta	84.76	0.00e+00	1268.00
IUUC-Meu-056212	Macropus eugenii	68.83	6.00e-112	397.00
IUUC-Mor-057045	Magnaporthe oryzae	37.89	1.00e-87	318.00
IUUC-Mla-059187	Melampsora laricipopulina	44.16	3.00e-91	328.00
IUUC-Mga-059884	Meleagris gallopavo	87.89	0.00e+00	1301.00
IUUC-Mmr-061344	Microcebus murinus	85.62	0.00e+00	1299.00
IUUC-Mdo-062653	Monodelphis domestica	85.60	0.00e+00	1284.00
IUUC-Mmu-063775	Mus musculus	83.74	0.00e+00	1214.00
IUUC-Mpu-066069	Mustela putorius furo	88.22	0.00e+00	1237.00
IUUC-Mlu-067925	Myotis lucifugus	85.64	0.00e+00	1295.00
IUUC-Nfi-068439	Neosartorya fischeri	33.17	2.00e-90	327.00
IUUC-Ncr-068903	Neurospora crassa	37.75	1.00e-92	334.00
IUUC-Nle-070046	Nomascus leucogenys	84.90	0.00e+00	1296.00
IUUC-Opr-071085	Ochotona princeps	75.84	3.00e-131	462.00
IUUC-Ont-072126	Oreochromis niloticus	75.37	0.00e+00	1183.00
IUUC-Oan-072933	Ornithorhynchus anatinus	87.33	0.00e+00	1170.00
IUUC-Ocu-073800	Oryctolagus cuniculus	88.22	0.00e+00	1223.00
IUUC-Ola-086988	Oryzias latipes	77.73	0.00e+00	1145.00
IUUC-Oga-088117	Otolemur garnettii	88.28	0.00e+00	1066.00
IUUC-Oar-089371	Ovis aries	85.91	0.00e+00	1286.00
IUUC-Ptr-090551	Pan troglodytes	84.04	0.00e+00	1250.00
IUUC-Pan-092067	Papio anubis	85.23	0.00e+00	1274.00
IUUC-Psi-092963	Pelodiscus sinensis	89.47	0.00e+00	1296.00
IUUC-Pfo-096562	Poecilia formosa	73.02	0.00e+00	1146.00
IUUC-Pab-098680	Pongo abelii	84.95	0.00e+00	1289.00
IUUC-Pca-100986	Procavia capensis	71.33	0.00e+00	861.00
IUUC-Pva-102219	Pteropus vampyrus	72.07	0.00e+00	973.00
IUUC-Pgr-103315	Puccinia graminis	35.90	3.00e-95	343.00
IUUC-Ptt-103736	Puccinia triticina	41.51	2.00e-94	340.00
IUUC-Rno-105270	Rattus norvegicus	83.86	0.00e+00	1221.00
IUUC-Sce-106306	Saccharomyces cerevisiae	34.84	2.00e-71	263.00
IUUC-Sha-106819	Sarcophilus harrisii	86.73	0.00e+00	1335.00
IUUC-Spo-108271	Schizosaccharomyces pombe	33.21	3.00e-84	306.00
IUUC-Ssl-108657	Sclerotinia sclerotiorum	38.98	4.00e-81	296.00
IUUC-Sar-113134	Sorex araneus	77.70	0.00e+00	1142.00
IUUC-Ssc-115441	Sus scrofa	86.32	0.00e+00	1300.00
IUUC-Tgu-117166	Taeniopygia guttata	95.90	0.00e+00	1394.00
IUUC-Tsy-118898	Tarsius syrichta	73.43	0.00e+00	1021.00
IUUC-Tre-122108	Trichoderma reesei	37.30	3.00e-88	320.00
IUUC-Tvi-122644	Trichoderma virens	37.70	2.00e-93	337.00
IUUC-Tme-127004	Tuber melanosporum	33.94	4.00e-100	359.00
IUUC-Tbe-127292	Tupaia belangeri	69.49	0.00e+00	974.00
IUUC-Ttr-128352	Tursiops truncatus	82.22	0.00e+00	1240.00
IUUC-Vda-129969	Verticillium dahliae	39.12	1.00e-90	327.00
IUUC-Vpa-130218	Vicugna pacos	82.96	0.00e+00	927.00
IUUC-Xtr-132594	Xenopus tropicalis	79.62	0.00e+00	1176.00
IUUC-Xma-134157	Xiphophorus maculatus	76.39	0.00e+00	1064.00
IUUC-Yli-134470	Yarrowia lipolytica	34.55	2.00e-76	280.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence