iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000009882.1	ENSSHAT00000011591.1	ENSSHAP00000011495.1
ENSSHAG00000009882.1	ENSSHAT00000011592.1	ENSSHAP00000011496.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	5.30e-10	39.7	34	94

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           +Dv++ v+ +ef+ah+ vLa  S++F+ lf        ++  ++++ ++p+ f+++l++ Yt +l+ 
   Q: 34   CDVVIMVDSQEFHAHRTVLACTSKMFEILFHR------NSQHYTLDFLSPKTFQQILEYAYTATLQA 94
           8*****************************33......3668889989***************9985 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

MDLTKMGMIQ LQNPSHPTGL LCKANQMRLA GTLCDVVIMV DSQEFHAHRT VLACTSKMFE 60
ILFHRNSQHY TLDFLSPKTF QQILEYAYTA TLQAKAEDLD DLLYAAEILE IEYLEEQCLK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAAAATAAAA TAAAAAGGAA AAATCCTCCC AAAATTACAG ATCTAAAACC CATCTGCTTC 60
CAGACTTCGG TCAATCAAAA TTTATTAAGC AGCTACTGTG TGCTAAGATT TTCTTACTCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000210--BTB/POZ_dom
IPR011333--SKP1/BTB/POZ
IPR013087--Znf_C2H2_type
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50097--BTB
PS00028--ZINC_FINGER_C2H2_1
PS50157--ZINC_FINGER_C2H2_2

Pfam

PF00651--BTB

SMART

SM00225--BTB
SM00355--ZnF_C2H2

Gene Ontology

GO:0016607--C:nuclear speck
GO:0016605--C:PML body
GO:0017053--C:transcriptional repressor complex
GO:0046872--F:metal ion binding
GO:0000980--F:RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0001206--F:transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding
GO:0009952--P:anterior/posterior pattern specification
GO:0051216--P:cartilage development
GO:0007417--P:central nervous system development
GO:0035116--P:embryonic hindlimb morphogenesis
GO:0009880--P:embryonic pattern specification
GO:0035136--P:forelimb morphogenesis
GO:0030097--P:hemopoiesis
GO:0048133--P:male germ-line stem cell asymmetric division
GO:0001823--P:mesonephros development
GO:0008285--P:negative regulation of cell proliferation
GO:0045638--P:negative regulation of myeloid cell differentiation
GO:0043065--P:positive regulation of apoptotic process
GO:0032332--P:positive regulation of chondrocyte differentiation
GO:0045600--P:positive regulation of fat cell differentiation
GO:0051138--P:positive regulation of NK T cell differentiation
GO:0045778--P:positive regulation of ossification
GO:0045893--P:positive regulation of transcription, DNA-templated

KEGG

shr:100933393

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001304	Ailuropoda melanoleuca	90.36	0.00e+00	1199.00
IUUC-Apl-003955	Anas platyrhynchos	85.91	0.00e+00	1158.00
IUUC-Aca-005156	Anolis carolinensis	71.16	5.00e-145	506.00
IUUC-Ame-011629	Astyanax mexicanus	76.54	0.00e+00	936.00
IUUC-Bta-012807	Bos taurus	90.36	0.00e+00	1202.00
IUUC-Cel-018262	Caenorhabditis elegans	29.46	2.00e-24	107.00
IUUC-Cja-019347	Callithrix jacchus	91.54	0.00e+00	1245.00
IUUC-Cfa-020219	Canis familiaris	89.91	0.00e+00	1172.00
IUUC-Cpo-021404	Cavia porcellus	87.98	0.00e+00	1152.00
IUUC-Csa-023837	Chlorocebus sabaeus	91.54	0.00e+00	1246.00
IUUC-Cho-024691	Choloepus hoffmanni	78.60	0.00e+00	786.00
IUUC-Dre-027842	Danio rerio	77.61	0.00e+00	966.00
IUUC-Dno-029711	Dasypus novemcinctus	91.25	0.00e+00	1223.00
IUUC-Ete-032980	Echinops telfairi	91.25	0.00e+00	1222.00
IUUC-Eca-033437	Equus caballus	91.25	0.00e+00	1217.00
IUUC-Fca-035631	Felis catus	85.58	0.00e+00	661.00
IUUC-Fal-037329	Ficedula albicollis	80.49	0.00e+00	1013.00
IUUC-Gmo-039421	Gadus morhua	71.28	0.00e+00	843.00
IUUC-Gga-041063	Gallus gallus	85.76	0.00e+00	1129.00
IUUC-Gac-041889	Gasterosteus aculeatus	71.51	0.00e+00	867.00
IUUC-Ggo-045452	Gorilla gorilla	91.69	0.00e+00	1248.00
IUUC-Hsa-046824	Homo sapiens	91.54	0.00e+00	1246.00
IUUC-Itr-048417	Ictidomys tridecemlineatus	88.58	0.00e+00	1187.00
IUUC-Lch-049446	Latimeria chalumnae	70.73	4.00e-159	553.00
IUUC-Loc-051811	Lepisosteus oculatus	79.68	0.00e+00	1014.00
IUUC-Laf-053594	Loxodonta africana	91.54	0.00e+00	1245.00
IUUC-Mcc-054941	Macaca mulatta	91.54	0.00e+00	1246.00
IUUC-Mga-059231	Meleagris gallopavo	85.46	0.00e+00	1118.00
IUUC-Mmr-061486	Microcebus murinus	86.34	0.00e+00	1142.00
IUUC-Mdo-063075	Monodelphis domestica	97.33	0.00e+00	1332.00
IUUC-Mmu-063142	Mus musculus	90.95	0.00e+00	1232.00
IUUC-Mpu-066057	Mustela putorius furo	90.06	0.00e+00	1206.00
IUUC-Mlu-067412	Myotis lucifugus	90.37	0.00e+00	1234.00
IUUC-Nle-069210	Nomascus leucogenys	91.69	0.00e+00	1248.00
IUUC-Opr-070631	Ochotona princeps	86.07	0.00e+00	1126.00
IUUC-Ont-071326	Oreochromis niloticus	75.41	0.00e+00	912.00
IUUC-Oan-073311	Ornithorhynchus anatinus	70.89	4.00e-77	280.00
IUUC-Ocu-074156	Oryctolagus cuniculus	90.95	0.00e+00	1195.00
IUUC-Ola-086952	Oryzias latipes	58.62	0.00e+00	676.00
IUUC-Oga-088714	Otolemur garnettii	91.69	0.00e+00	1220.00
IUUC-Ptr-090490	Pan troglodytes	89.68	0.00e+00	1073.00
IUUC-Pan-092563	Papio anubis	91.54	0.00e+00	1246.00
IUUC-Psi-093644	Pelodiscus sinensis	84.57	0.00e+00	1108.00
IUUC-Pma-094677	Petromyzon marinus	50.88	1.00e-156	546.00
IUUC-Pfo-096399	Poecilia formosa	74.89	0.00e+00	915.00
IUUC-Pab-097934	Pongo abelii	90.65	0.00e+00	1082.00
IUUC-Pca-101003	Procavia capensis	84.87	0.00e+00	1130.00
IUUC-Pva-102802	Pteropus vampyrus	89.30	0.00e+00	1058.00
IUUC-Rno-105871	Rattus norvegicus	90.80	0.00e+00	1231.00
IUUC-Sar-113057	Sorex araneus	82.03	2.00e-173	602.00
IUUC-Ssc-116179	Sus scrofa	86.52	0.00e+00	682.00
IUUC-Tgu-116805	Taeniopygia guttata	73.12	0.00e+00	825.00
IUUC-Tru-118282	Takifugu rubripes	59.50	0.00e+00	701.00
IUUC-Tni-120296	Tetraodon nigroviridis	58.95	0.00e+00	709.00
IUUC-Tbe-127742	Tupaia belangeri	82.89	0.00e+00	1088.00
IUUC-Ttr-128285	Tursiops truncatus	90.95	0.00e+00	1214.00
IUUC-Xtr-132970	Xenopus tropicalis	76.59	0.00e+00	997.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence