iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Afu-008903

Ensembl Protein ID

CADAFUAP00003457

UniProt Accession

Q4WHB7; JHD1_ASPFU

Genbank Protein ID

EAL87688.1

Protein Name

JmjC domain-containing histone demethylation protein 1; [Histone-H3]-lysine-36 demethylase 1

Genbank Nucleotide ID

AAHF01000008

Gene Name

AFUA_2G05970; jhd1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CADAFUAG00003457	CADAFUAT00003457	CADAFUAP00003457

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/SCF/F-box	48.06	3.00e-69	261.00	IUUC-Dme-032039

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Aspergillus fumigatus

Functional Description
(View)

Histone demethylase that specifically demethylates 'Lys-36' of histone H3, thereby playing a central role in histone code.

Protein Sequence
(Fasta)

MIGATSFLNH SGPRPPRYRT PSPPRRAVEP ISPFTTTTDF RASWIDRGDS QAASYDRDRV 60
TSNNDVYSST NRGSHGRTSH GRSSSTIDTL ATIALATSPT FAPLSYRPPS QDPTPAMPLF 120

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Nucleotide Sequence
(Fasta)

ATGATAGGTG CCACGTCCTT CTTGAACCAC TCCGGGCCTC GACCGCCGCG ATATCGCACT 60
CCGTCTCCTC CGCGACGCGC CGTGGAGCCT ATCTCTCCTT TCACCACCAC CACCGACTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0223--Dioxygenase
KW-0408--Iron
KW-0479--Metal-binding
KW-0539--Nucleus
KW-0560--Oxidoreductase
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR003347--JmjC_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR001138--Zn2-C6_fun-type_DNA-bd
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51184--JMJC
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF02373--JmjC
PF00628--PHD

SMART

SM00558--JmjC
SM00249--PHD

Gene Ontology

GO:0005634--C:nucleus
GO:0051864--F:histone demethylase activity (H3-K36 specific)
GO:0008270--F:zinc ion binding
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated

KEGG

afm:AFUA_2G05970

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002427	Ailuropoda melanoleuca	32.53	2.00e-67	248.00
IUUC-Apl-003192	Anas platyrhynchos	44.76	1.00e-65	243.00
IUUC-Aca-004346	Anolis carolinensis	31.31	4.00e-67	248.00
IUUC-Ago-007912	Ashbya gossypii	44.67	6.00e-58	216.00
IUUC-Acl-008303	Aspergillus clavatus	77.62	0.00e+00	2027.00
IUUC-Afl-008579	Aspergillus flavus	73.84	0.00e+00	759.00
IUUC-Ani-009279	Aspergillus nidulans	64.45	0.00e+00	1593.00
IUUC-Ang-009645	Aspergillus niger	71.88	0.00e+00	1480.00
IUUC-Aor-010233	Aspergillus oryzae	74.78	0.00e+00	1571.00
IUUC-Ate-010345	Aspergillus terreus	69.28	0.00e+00	1713.00
IUUC-Ame-011753	Astyanax mexicanus	47.71	5.00e-68	251.00
IUUC-Bta-013531	Bos taurus	45.25	3.00e-64	239.00
IUUC-Cel-018303	Caenorhabditis elegans	37.13	3.00e-57	215.00
IUUC-Cja-019030	Callithrix jacchus	44.41	4.00e-63	234.00
IUUC-Cfa-021156	Canis familiaris	33.33	2.00e-68	252.00
IUUC-Cpo-022284	Cavia porcellus	31.92	8.00e-68	250.00
IUUC-Cre-022852	Chlamydomonas reinhardtii	28.26	1.40e-02	33.90
IUUC-Csa-023515	Chlorocebus sabaeus	33.56	9.00e-68	250.00
IUUC-Cho-024541	Choloepus hoffmanni	41.53	2.00e-44	172.00
IUUC-Cin-025140	Ciona intestinalis	46.69	4.00e-67	247.00
IUUC-Csv-025861	Ciona savignyi	46.24	5.00e-70	257.00
IUUC-Cne-026797	Cryptococcus neoformans	34.08	2.00e-56	212.00
IUUC-Cme-027118	Cyanidioschyzon merolae	36.36	4.00e-45	174.00
IUUC-Dre-028423	Danio rerio	32.64	7.00e-67	247.00
IUUC-Dno-029446	Dasypus novemcinctus	31.98	2.00e-66	244.00
IUUC-Dor-030736	Dipodomys ordii	42.11	8.00e-63	234.00
IUUC-Dse-031402	Dothistroma septosporum	45.54	0.00e+00	748.00
IUUC-Dme-032039	Drosophila melanogaster	48.25	6.00e-71	261.00
IUUC-Ete-032380	Echinops telfairi	32.75	2.00e-67	249.00
IUUC-Eca-034302	Equus caballus	33.79	8.00e-68	250.00
IUUC-Eeu-035273	Erinaceus europaeus	51.70	5.00e-53	201.00
IUUC-Fca-035578	Felis catus	32.12	1.00e-67	249.00
IUUC-Fal-037140	Ficedula albicollis	44.76	2.00e-65	242.00
IUUC-Gmo-038789	Gadus morhua	33.87	2.00e-67	249.00
IUUC-Gga-040418	Gallus gallus	44.76	4.00e-65	241.00
IUUC-Gac-041914	Gasterosteus aculeatus	47.81	2.00e-67	249.00
IUUC-Ggo-044712	Gorilla gorilla	34.25	8.00e-69	253.00
IUUC-Hsa-045724	Homo sapiens	33.79	2.00e-68	252.00
IUUC-Kpa-049384	Komagataella pastoris	35.29	3.00e-70	257.00
IUUC-Lch-049950	Latimeria chalumnae	44.06	9.00e-65	240.00
IUUC-Loc-051972	Lepisosteus oculatus	46.61	4.00e-62	231.00
IUUC-Lma-053190	Leptosphaeria maculans	49.36	0.00e+00	765.00
IUUC-Laf-053656	Loxodonta africana	33.79	2.00e-67	249.00
IUUC-Mcc-055658	Macaca mulatta	33.56	9.00e-68	250.00
IUUC-Meu-056259	Macropus eugenii	43.51	7.00e-60	224.00
IUUC-Mla-058890	Melampsora laricipopulina	53.78	1.00e-76	277.00
IUUC-Mga-059549	Meleagris gallopavo	44.76	2.00e-65	242.00
IUUC-Mvi-060481	Microbotryum violaceum	35.29	4.00e-79	288.00
IUUC-Mmr-060993	Microcebus murinus	33.56	2.00e-67	249.00
IUUC-Mdo-062567	Monodelphis domestica	44.76	1.00e-63	236.00
IUUC-Mmu-063909	Mus musculus	31.98	2.00e-67	249.00
IUUC-Mpu-066429	Mustela putorius furo	33.79	2.00e-67	249.00
IUUC-Mlu-067746	Myotis lucifugus	34.48	6.00e-69	254.00
IUUC-Nfi-068537	Neosartorya fischeri	95.15	0.00e+00	2571.00
IUUC-Nle-070143	Nomascus leucogenys	33.79	3.00e-68	251.00
IUUC-Opr-070225	Ochotona princeps	44.41	4.00e-63	234.00
IUUC-Ont-072151	Oreochromis niloticus	44.18	6.00e-67	248.00
IUUC-Oan-073668	Ornithorhynchus anatinus	45.04	5.00e-61	226.00
IUUC-Ocu-074417	Oryctolagus cuniculus	33.33	1.00e-67	249.00
IUUC-Oba-075590	Oryza barthii	30.23	3.00e-03	37.00
IUUC-Ome-081615	Oryza meridionalis	30.23	3.00e-03	37.00
IUUC-Ola-087410	Oryzias latipes	44.20	6.00e-68	251.00
IUUC-Oga-088662	Otolemur garnettii	33.56	1.00e-66	246.00
IUUC-Oar-090332	Ovis aries	32.19	6.00e-68	250.00
IUUC-Ptr-091646	Pan troglodytes	33.79	5.00e-67	247.00
IUUC-Pan-092122	Papio anubis	33.56	9.00e-68	250.00
IUUC-Psi-093114	Pelodiscus sinensis	43.94	1.00e-64	239.00
IUUC-Pma-094621	Petromyzon marinus	35.24	7.00e-65	239.00
IUUC-Pno-094984	Phaeosphaeria nodorum	49.46	0.00e+00	766.00
IUUC-Ppa-095609	Physcomitrella patens	41.11	7.00e-52	195.00
IUUC-Pfo-096695	Poecilia formosa	46.15	5.00e-69	254.00
IUUC-Pab-097907	Pongo abelii	43.71	2.00e-64	239.00
IUUC-Pop-098947	Populus trichocarpa	30.23	3.00e-03	36.60
IUUC-Pca-100628	Procavia capensis	48.39	3.00e-53	202.00
IUUC-Pva-102416	Pteropus vampyrus	44.41	6.00e-63	234.00
IUUC-Pgr-103554	Puccinia graminis	56.61	6.00e-80	290.00
IUUC-Ptt-103859	Puccinia triticina	40.05	9.00e-83	299.00
IUUC-Pte-104241	Pyrenophora teres	48.23	0.00e+00	768.00
IUUC-Pyt-104741	Pyrenophora triticirepentis	49.00	0.00e+00	763.00
IUUC-Rno-105933	Rattus norvegicus	33.79	8.00e-68	250.00
IUUC-Sce-106445	Saccharomyces cerevisiae	30.29	3.00e-55	207.00
IUUC-Sha-106693	Sarcophilus harrisii	44.76	1.00e-63	236.00
IUUC-Sja-107763	Schizosaccharomyces japonicus	34.22	3.00e-56	211.00
IUUC-Spo-108120	Schizosaccharomyces pombe	32.42	2.00e-57	215.00
IUUC-Smo-109024	Selaginella moellendorffii	41.59	1.00e-51	196.00
IUUC-Sly-111176	Solanum lycopersicum	39.66	3.00e-05	42.70
IUUC-Stu-112041	Solanum tuberosum	39.66	5.00e-05	41.60
IUUC-Sar-113568	Sorex araneus	44.06	1.00e-61	230.00
IUUC-Sre-115112	Sporisorium reilianum	35.28	7.00e-75	273.00
IUUC-Ssc-115645	Sus scrofa	33.79	2.00e-67	249.00
IUUC-Tgu-117229	Taeniopygia guttata	44.70	3.00e-64	238.00
IUUC-Tru-118423	Takifugu rubripes	43.26	9.00e-69	253.00
IUUC-Tsy-119214	Tarsius syrichta	32.90	1.00e-67	249.00
IUUC-Tni-120753	Tetraodon nigroviridis	42.59	1.00e-67	249.00
IUUC-Tme-127054	Tuber melanosporum	41.13	3.00e-110	391.00
IUUC-Tbe-128138	Tupaia belangeri	40.91	3.00e-61	228.00
IUUC-Ttr-129014	Tursiops truncatus	31.30	1.00e-52	199.00
IUUC-Uma-129458	Ustilago maydis	35.17	2.00e-80	291.00
IUUC-Vpa-130655	Vicugna pacos	41.26	3.00e-54	205.00
IUUC-Xtr-131839	Xenopus tropicalis	44.76	1.00e-66	246.00
IUUC-Xma-133499	Xiphophorus maculatus	46.15	5.00e-68	251.00
IUUC-Yli-134626	Yarrowia lipolytica	37.35	7.00e-84	302.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence