iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066452

Ensembl Protein ID

ENSMPUP00000003665.1

UniProt Accession

M3XX65; M3XX65_MUSPF

Genbank Protein ID

ENSMPUP00000003665

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01071634

Gene Name

RNF128

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000003695.1	ENSMPUT00000003733.1	ENSMPUP00000003665.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	5.30e-06	26.9	242	283

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf..kdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           Ca+C e +   d +++l C+H+fh++C+  w         + +CP C+
   Q: 242  CAVCIELYkpNDLVRILTCNHIFHKTCVDPW------LLEHRTCPMCK 283
           *****9985545499****************......9999******6 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

AEAVWTAYLN VSWRVPHTGV NRTVWELSEE GVYGQDSPLE PVAGVLVPPD GPGALNACNP 60
HTNFTVPTVP GDWGSSVQVS WLALIQRGGG CTFADKIHLA YERGASGAVI FNFPGTRNEV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCGAGGCCG TGTGGACCGC GTACCTCAAC GTGTCCTGGC GGGTTCCGCA CACCGGAGTG 60
AACCGCACAG TGTGGGAGCT GAGCGAGGAG GGCGTGTACG GCCAGGATTC GCCGCTCGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR003137--PA_domain
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF02225--PA
PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0005783--C:endoplasmic reticulum
GO:0005794--C:Golgi apparatus
GO:0016021--C:integral component of membrane
GO:0005770--C:late endosome
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0042036--P:negative regulation of cytokine biosynthetic process
GO:0031647--P:regulation of protein stability

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000408	Aegilops tauschii	48.21	1.00e-12	66.60
IUUC-Aml-001674	Ailuropoda melanoleuca	92.73	6.00e-176	610.00
IUUC-Apl-003776	Anas platyrhynchos	60.66	3.00e-95	341.00
IUUC-Aca-004318	Anolis carolinensis	64.87	5.00e-91	327.00
IUUC-Ame-011286	Astyanax mexicanus	47.64	7.00e-72	264.00
IUUC-Bta-013454	Bos taurus	92.42	3.00e-175	607.00
IUUC-Cja-019864	Callithrix jacchus	91.82	7.00e-172	596.00
IUUC-Cfa-020185	Canis familiaris	92.12	7.00e-174	603.00
IUUC-Cpo-021838	Cavia porcellus	45.85	1.00e-76	280.00
IUUC-Csa-023224	Chlorocebus sabaeus	91.52	1.00e-171	595.00
IUUC-Cho-024710	Choloepus hoffmanni	81.10	5.00e-143	500.00
IUUC-Dre-028249	Danio rerio	54.64	2.00e-77	282.00
IUUC-Dno-029216	Dasypus novemcinctus	93.33	3.00e-114	404.00
IUUC-Dor-030487	Dipodomys ordii	81.52	1.00e-146	512.00
IUUC-Dse-031357	Dothistroma septosporum	43.04	1.00e-12	67.80
IUUC-Ete-032376	Echinops telfairi	87.38	5.00e-91	327.00
IUUC-Eca-034264	Equus caballus	92.73	2.00e-175	608.00
IUUC-Eeu-034606	Erinaceus europaeus	94.34	2.00e-110	392.00
IUUC-Fca-036503	Felis catus	92.42	8.00e-175	606.00
IUUC-Fal-036671	Ficedula albicollis	57.54	6.00e-89	320.00
IUUC-Gmo-039483	Gadus morhua	45.70	4.00e-70	258.00
IUUC-Gga-040248	Gallus gallus	62.26	2.00e-101	362.00
IUUC-Ggo-045319	Gorilla gorilla	52.79	9.00e-87	313.00
IUUC-Hsa-046745	Homo sapiens	91.52	2.00e-170	592.00
IUUC-Itr-048362	Ictidomys tridecemlineatus	91.82	4.00e-172	597.00
IUUC-Lch-050549	Latimeria chalumnae	55.86	9.00e-95	340.00
IUUC-Loc-051929	Lepisosteus oculatus	55.66	1.00e-86	313.00
IUUC-Laf-054197	Loxodonta africana	92.12	4.00e-174	603.00
IUUC-Mcc-055146	Macaca mulatta	91.52	1.00e-171	595.00
IUUC-Meu-056649	Macropus eugenii	73.95	2.00e-127	449.00
IUUC-Mga-059520	Meleagris gallopavo	62.26	1.00e-101	363.00
IUUC-Mmr-061502	Microcebus murinus	90.91	3.00e-170	591.00
IUUC-Mdo-062875	Monodelphis domestica	61.28	1.00e-91	329.00
IUUC-Mmu-064235	Mus musculus	91.21	8.00e-171	593.00
IUUC-Mlu-067189	Myotis lucifugus	91.52	4.00e-170	590.00
IUUC-Nle-070026	Nomascus leucogenys	91.82	9.00e-172	596.00
IUUC-Opr-070767	Ochotona princeps	52.79	3.00e-89	321.00
IUUC-Oan-073238	Ornithorhynchus anatinus	69.44	1.00e-103	369.00
IUUC-Ocu-074960	Oryctolagus cuniculus	90.61	2.00e-168	585.00
IUUC-Ola-086348	Oryzias latipes	42.41	4.00e-67	248.00
IUUC-Oga-088543	Otolemur garnettii	90.00	7.00e-169	586.00
IUUC-Oar-089599	Ovis aries	92.12	3.00e-174	604.00
IUUC-Ptr-091576	Pan troglodytes	85.55	7.00e-121	426.00
IUUC-Pan-091690	Papio anubis	91.24	3.00e-170	590.00
IUUC-Psi-093642	Pelodiscus sinensis	71.56	1.00e-71	263.00
IUUC-Pfo-096270	Poecilia formosa	42.86	2.00e-67	249.00
IUUC-Pab-097965	Pongo abelii	91.82	2.00e-171	595.00
IUUC-Pva-102991	Pteropus vampyrus	81.21	3.00e-143	501.00
IUUC-Rno-105667	Rattus norvegicus	91.21	4.00e-171	593.00
IUUC-Sha-107293	Sarcophilus harrisii	75.16	5.00e-123	434.00
IUUC-Sar-113682	Sorex araneus	89.16	4.00e-98	350.00
IUUC-Ssc-115583	Sus scrofa	92.73	2.00e-175	608.00
IUUC-Tgu-117406	Taeniopygia guttata	53.18	7.00e-72	263.00
IUUC-Tru-118147	Takifugu rubripes	42.72	1.00e-64	239.00
IUUC-Tsy-118918	Tarsius syrichta	90.91	4.00e-162	563.00
IUUC-Tni-120865	Tetraodon nigroviridis	42.53	1.00e-60	226.00
IUUC-Tbe-127498	Tupaia belangeri	56.31	6.00e-100	357.00
IUUC-Ttr-128640	Tursiops truncatus	93.33	9.00e-167	579.00
IUUC-Vpa-130536	Vicugna pacos	83.08	2.00e-148	518.00
IUUC-Xma-133114	Xiphophorus maculatus	44.03	1.00e-67	249.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence