iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Details
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Ath-006846

UUCD1 version

UUC-ArT-01607

Ensembl Protein ID

AT2G18600.1

UniProt Accession

Q9ZU75; UB12L_ARATH

Genbank Protein ID

AAD12207.1; AEC06784.1; ANM62258.1; AAO41960.1; AAO50538.1

Protein Name

Probable NEDD8-conjugating enzyme Ubc12-like; RUB1 carrier protein 2; RUB1-conjugating enzyme 2; RUB1-protein ligase 2

Genbank Nucleotide ID

AC006135; CP002685; CP002685; BT003913; BT005005

Gene Name

RCE2; At2g18600; F24H14.5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AT2G18600	AT2G18600.1	AT2G18600.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
TRANSFAC
Protein Expression/Proteomics
GPMDB

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E2/UBC	E2_UBC	21311953

Classification

Family	E-value	Score	Start	End
E2/UBC	2.40e-36	125.4	35	168

Active Site

Position(s)	Description	Evidence
114	Glycyl thioester intermediate	{ECO:0000255\|PROSITE-ProRule:PRU00388, ECO:0000255\|PROSITE-ProRule:PRU10133}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkeeekWspalsv 98
           Rl+k+++el+  ++ +is  p+ ++dl+++ev+i  p++ +Y  g F +++++++ YP ++Pkvk+ tk++hPn++ +G+vCl+il+  e+W+p+l++
   Q: 35   RLHKDISELNLPKSCKISF-PNGKNDLMNFEVTIK-PDEGYYLSGNFVFSFQVSNMYPHEAPKVKCKTKVYHPNIDLEGNVCLNILR--EDWKPVLNI 128
           899*****95555555544.455558*********.**************************************************9..********* PP
   S: 99   esvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           ++v++++  l++epn+e+pln+eaa  l++n+++++ +vr
   Q: 129  NTVIYGLFHLFTEPNYEDPLNHEAAAVLRDNPKTFEYNVR 168
           ************************************9997 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

Accepts the ubiquitin-like protein NEDD8/RUB1 from the ECR1-AXR1 E1 complex and catalyzes its covalent attachment to other proteins.

Protein Sequence
(Fasta)

MIGLFKVKEK QREESQSNNG RGASTVKKQS AGELRLHKDI SELNLPKSCK ISFPNGKNDL 60
MNFEVTIKPD EGYYLSGNFV FSFQVSNMYP HEAPKVKCKT KVYHPNIDLE GNVCLNILRE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGTAATATTA GTTTCGGATT TTCATTATAT ATATAGTTTG AAGAAGGGTT GTAATTTTTT 60
CAGAATCAGC TTACGGAGAA AGCTACGTTC GTTCGTTCCT CGTCGAACCA AATCAATAGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0436--Ligase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0016874--F:ligase activity
GO:0019788--F:NEDD8 transferase activity
GO:0045116--P:protein neddylation

KEGG

ath:AT2G18600

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aly-006219	Arabidopsis lyrata	92.43	6.00e-102	362.00
IUUC-Acl-008364	Aspergillus clavatus	58.55	2.00e-48	184.00
IUUC-Afl-008463	Aspergillus flavus	58.55	4.00e-49	186.00
IUUC-Afu-008803	Aspergillus fumigatus	58.55	1.00e-48	184.00
IUUC-Ang-009728	Aspergillus niger	60.29	3.00e-44	169.00
IUUC-Aor-009962	Aspergillus oryzae	58.55	4.00e-49	186.00
IUUC-Ate-010430	Aspergillus terreus	55.28	4.00e-45	173.00
IUUC-Bta-012818	Bos taurus	62.16	1.00e-65	241.00
IUUC-Cel-018579	Caenorhabditis elegans	39.66	2.00e-18	84.30
IUUC-Cja-019213	Callithrix jacchus	60.53	1.00e-63	234.00
IUUC-Cfa-020242	Canis familiaris	61.50	4.00e-64	236.00
IUUC-Cpo-022405	Cavia porcellus	59.46	8.00e-61	225.00
IUUC-Csa-023269	Chlorocebus sabaeus	62.16	1.00e-65	241.00
IUUC-Cin-025333	Ciona intestinalis	58.38	1.00e-60	224.00
IUUC-Csv-025898	Ciona savignyi	49.08	3.00e-54	204.00
IUUC-Cgl-026477	Colletotrichum gloeosporioides	58.17	3.00e-49	186.00
IUUC-Cne-027097	Cryptococcus neoformans	50.81	3.00e-50	190.00
IUUC-Cme-027287	Cyanidioschyzon merolae	48.68	5.00e-18	83.60
IUUC-Dre-028514	Danio rerio	60.54	2.00e-61	227.00
IUUC-Dno-029678	Dasypus novemcinctus	57.84	4.00e-59	219.00
IUUC-Eca-034075	Equus caballus	61.62	2.00e-64	237.00
IUUC-Fal-037283	Ficedula albicollis	64.29	2.00e-28	115.00
IUUC-Fox-037877	Fusarium oxysporum	49.73	2.00e-48	184.00
IUUC-Fso-038428	Fusarium solani	50.81	3.00e-52	197.00
IUUC-Ggr-039731	Gaeumannomyces graminis	56.86	9.00e-48	181.00
IUUC-Gga-041122	Gallus gallus	55.85	4.00e-57	213.00
IUUC-Gac-041480	Gasterosteus aculeatus	39.10	9.00e-27	112.00
IUUC-Ggo-044436	Gorilla gorilla	62.16	1.00e-65	241.00
IUUC-Hsa-046026	Homo sapiens	62.16	1.00e-65	241.00
IUUC-Itr-047889	Ictidomys tridecemlineatus	62.16	1.00e-65	241.00
IUUC-Lch-050360	Latimeria chalumnae	67.27	6.00e-40	156.00
IUUC-Loc-052137	Lepisosteus oculatus	39.26	7.00e-28	115.00
IUUC-Lma-053001	Leptosphaeria maculans	55.77	6.00e-48	182.00
IUUC-Mcc-054966	Macaca mulatta	74.03	1.00e-31	126.00
IUUC-Mor-057250	Magnaporthe oryzae	56.58	7.00e-47	179.00
IUUC-Mpo-057481	Magnaporthe poae	56.58	5.00e-47	179.00
IUUC-Mla-059119	Melampsora laricipopulina	52.49	1.00e-50	191.00
IUUC-Mga-059881	Meleagris gallopavo	66.98	3.00e-39	152.00
IUUC-Mmr-061511	Microcebus murinus	74.03	1.00e-31	126.00
IUUC-Mdo-061993	Monodelphis domestica	38.85	2.00e-27	115.00
IUUC-Mmu-063962	Mus musculus	62.16	1.00e-65	241.00
IUUC-Mpu-066423	Mustela putorius furo	45.60	6.00e-26	109.00
IUUC-Nfi-068300	Neosartorya fischeri	58.55	1.00e-48	184.00
IUUC-Oan-072779	Ornithorhynchus anatinus	44.90	1.00e-18	84.00
IUUC-Ocu-074905	Oryctolagus cuniculus	62.16	1.00e-65	241.00
IUUC-Oga-088580	Otolemur garnettii	62.16	1.00e-65	241.00
IUUC-Pma-094321	Petromyzon marinus	45.30	1.00e-23	101.00
IUUC-Pno-094972	Phaeosphaeria nodorum	51.22	4.00e-45	173.00
IUUC-Ppa-095439	Physcomitrella patens	72.97	2.00e-80	290.00
IUUC-Pfo-097205	Poecilia formosa	60.43	5.00e-60	223.00
IUUC-Pab-098434	Pongo abelii	62.16	1.00e-65	241.00
IUUC-Pva-102143	Pteropus vampyrus	62.16	1.00e-65	241.00
IUUC-Pgr-103675	Puccinia graminis	51.38	2.00e-50	191.00
IUUC-Ptt-103997	Puccinia triticina	51.38	5.00e-51	192.00
IUUC-Pte-104042	Pyrenophora teres	55.77	3.00e-48	183.00
IUUC-Pyt-104616	Pyrenophora triticirepentis	57.14	6.00e-46	175.00
IUUC-Rno-105107	Rattus norvegicus	62.16	1.00e-65	241.00
IUUC-Sja-107789	Schizosaccharomyces japonicus	44.75	2.00e-42	164.00
IUUC-Spo-108143	Schizosaccharomyces pombe	48.07	8.00e-46	175.00
IUUC-Ssl-108427	Sclerotinia sclerotiorum	51.74	8.00e-50	189.00
IUUC-Sar-113632	Sorex araneus	61.62	1.00e-64	238.00
IUUC-Sre-114912	Sporisorium reilianum	56.21	5.00e-51	192.00
IUUC-Ssc-115597	Sus scrofa	45.60	4.00e-26	110.00
IUUC-Tgu-117397	Taeniopygia guttata	40.43	2.00e-26	111.00
IUUC-Tru-118496	Takifugu rubripes	37.04	1.00e-26	112.00
IUUC-Tsy-119639	Tarsius syrichta	50.66	1.00e-37	147.00
IUUC-Tre-122115	Trichoderma reesei	56.60	3.00e-49	187.00
IUUC-Tvi-122656	Trichoderma virens	55.35	3.00e-48	183.00
IUUC-Tme-126950	Tuber melanosporum	55.13	2.00e-47	181.00
IUUC-Uma-129329	Ustilago maydis	55.92	2.00e-50	191.00
IUUC-Vda-129754	Verticillium dahliae	57.05	2.00e-49	187.00
IUUC-Xma-133558	Xiphophorus maculatus	61.08	2.00e-61	227.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence