iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ago-007901

Ensembl Protein ID

AAS52798

UniProt Accession

Q756Z9; Q756Z9_ASHGO

Genbank Protein ID

AAS52798.1

Protein Name

Coronin

Genbank Nucleotide ID

AE016818

Gene Name

AGOS_AER114W

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AGOS_AER114W	AAS52798	AAS52798

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.10e-20	70.9	79	110
UBD/Beta-Prp	2.30e-43	146.4	70	309

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sd.tllvsGsdDgtikvWD 29
           gHt+ v + +f   d ++lvsGsdDg i vW+
   Q: 79   GHTAQVLDTDFdpFDeRMLVSGSDDGRIGVWE 110
           8***********9666***************9 PP

UBD/Beta-Prp

   S: 83   tgkcvhtlkghedsvlslsfsp.sgdklvsGshdrtirvwdletgqclee...............tlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdl 166
           +++++  ++gh+++vl+++f+p +   lvsGs+d  i vw+++  + +++               +l+gh++ v +v +hp++  +l+s+slD tvrlW++
   Q: 70   APDQIPLFRGHTAQVLDTDFDPfDERMLVSGSDDGRIGVWEIPATYSFHNaqdedgnvehvapvkFLTGHQRKVGHVLYHPTAqGVLASSSLDHTVRLWNV 170
           7889999***************888**************************************************************************** PP
   S: 167  ktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfs.pnderlvsgs....sDgsiriW...dlrsgdllkt 259
           ++g+    lt  h d+v+s+sf++ g++l+++ +d+ +++wd+++ge+v +  gh+ + ++  ++  n++rl++++    sD++i +W   +l++g+l + 
   Q: 171  EQGTNPIVLT--HPDMVTSMSFSYGGTYLATVCRDKMLRVWDIRKGEVVSEGMGHSGPKNQRVVWlGNSDRLATTGfsklSDRQIAVWdafNLEKGQLGGF 269
           *********6..9************************************************99999*********************************** PP
   S: 260  lqlhnssvisvavlsfgdnvlvlgse.dskvniwklkkne 298
           ++  +ss i + +++ ++++l+ +++ d+++++++++ +e
   Q: 270  YNVDQSSGILMPFYDDSNKILYVAGKgDGNIRYYEFQDDE 309
           *************9999***9999889********98765 PP

Organism

Ashbya gossypii

Protein Sequence
(Fasta)

MSGKFVRASK YRHVFGQSTK KELFYENLKV TINAWDSNLI KTNGKFISVT WNSSGGGAFA 60
VVPVEEVGKA PDQIPLFRGH TAQVLDTDFD PFDERMLVSG SDDGRIGVWE IPATYSFHNA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGGTATG TCATACTCTC CAGGACTGGA CTTTGTGCGG ACGGCAAACT AACGGCACTG 60
CAGTGGGAAG TTTGTGCGGG CTTCCAAGTA TAGACACGTC TTCGGACAAT CAACAAAGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR015505--Coronin
IPR015048--DUF1899
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08953--DUF1899
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM01166--DUF1899
SM00320--WD40

Gene Ontology

GO:0030479--C:actin cortical patch
GO:1990819--C:actin fusion focus
GO:0005826--C:actomyosin contractile ring
GO:0005885--C:Arp2/3 protein complex
GO:0030139--C:endocytic vesicle
GO:0035838--C:growing cell tip
GO:0051015--F:actin filament binding
GO:0051666--P:actin cortical patch localization
GO:0030036--P:actin cytoskeleton organization
GO:0007015--P:actin filament organization
GO:0007017--P:microtubule-based process
GO:0034316--P:negative regulation of Arp2/3 complex-mediated actin nucleation
GO:2000601--P:positive regulation of Arp2/3 complex-mediated actin nucleation

KEGG

ago:AGOS_AER114W

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001462	Ailuropoda melanoleuca	40.39	5.00e-91	325.00
IUUC-Apl-003861	Anas platyrhynchos	39.80	2.00e-88	317.00
IUUC-Aca-005215	Anolis carolinensis	41.93	2.00e-90	323.00
IUUC-Acl-008280	Aspergillus clavatus	52.22	3.00e-134	469.00
IUUC-Afl-008393	Aspergillus flavus	54.68	3.00e-136	476.00
IUUC-Afu-008865	Aspergillus fumigatus	50.72	1.00e-130	458.00
IUUC-Ani-009155	Aspergillus nidulans	55.39	1.00e-138	484.00
IUUC-Ang-009523	Aspergillus niger	47.40	5.00e-126	442.00
IUUC-Aor-010049	Aspergillus oryzae	54.04	4.00e-131	459.00
IUUC-Ate-010368	Aspergillus terreus	51.23	4.00e-125	439.00
IUUC-Ame-011256	Astyanax mexicanus	40.49	3.00e-90	323.00
IUUC-Bgr-011990	Blumeria graminis	53.94	6.00e-139	485.00
IUUC-Bta-013168	Bos taurus	40.73	1.00e-89	321.00
IUUC-Bci-013935	Botrytis cinerea	56.49	2.00e-144	503.00
IUUC-Cel-018669	Caenorhabditis elegans	36.83	6.00e-67	246.00
IUUC-Cja-019934	Callithrix jacchus	40.15	2.00e-91	327.00
IUUC-Cfa-020414	Canis familiaris	38.11	1.00e-91	328.00
IUUC-Cpo-022256	Cavia porcellus	36.95	1.00e-92	331.00
IUUC-Csa-023319	Chlorocebus sabaeus	40.88	1.00e-91	327.00
IUUC-Cho-024687	Choloepus hoffmanni	40.79	2.00e-89	320.00
IUUC-Cin-025202	Ciona intestinalis	34.19	7.00e-55	206.00
IUUC-Csv-026184	Ciona savignyi	32.60	1.00e-54	204.00
IUUC-Cgl-026456	Colletotrichum gloeosporioides	52.17	6.00e-133	465.00
IUUC-Cne-026773	Cryptococcus neoformans	45.66	3.00e-108	384.00
IUUC-Dre-028541	Danio rerio	40.73	1.00e-90	324.00
IUUC-Dno-029363	Dasypus novemcinctus	41.22	2.00e-90	323.00
IUUC-Dor-030506	Dipodomys ordii	36.95	7.00e-93	332.00
IUUC-Dse-031378	Dothistroma septosporum	56.72	4.00e-137	479.00
IUUC-Dme-032091	Drosophila melanogaster	39.51	5.00e-84	302.00
IUUC-Ete-032839	Echinops telfairi	36.36	4.00e-73	266.00
IUUC-Eca-033550	Equus caballus	41.36	2.00e-93	333.00
IUUC-Eeu-034499	Erinaceus europaeus	38.04	3.00e-71	259.00
IUUC-Fca-035787	Felis catus	41.12	2.00e-93	333.00
IUUC-Fal-036737	Ficedula albicollis	41.03	1.00e-89	321.00
IUUC-Fox-037737	Fusarium oxysporum	54.77	2.00e-134	470.00
IUUC-Fso-038184	Fusarium solani	52.16	2.00e-135	473.00
IUUC-Gmo-038678	Gadus morhua	40.73	3.00e-90	323.00
IUUC-Ggr-039956	Gaeumannomyces graminis	53.98	9.00e-141	491.00
IUUC-Gga-040842	Gallus gallus	39.56	6.00e-89	319.00
IUUC-Gac-041543	Gasterosteus aculeatus	41.71	7.00e-86	308.00
IUUC-Ggo-044731	Gorilla gorilla	40.39	2.00e-91	327.00
IUUC-Hsa-046725	Homo sapiens	36.35	9.00e-92	328.00
IUUC-Itr-048296	Ictidomys tridecemlineatus	40.63	4.00e-91	325.00
IUUC-Kpa-049089	Komagataella pastoris	56.21	1.00e-174	603.00
IUUC-Lch-050453	Latimeria chalumnae	40.73	2.00e-89	320.00
IUUC-Loc-052911	Lepisosteus oculatus	40.00	3.00e-90	323.00
IUUC-Lma-053160	Leptosphaeria maculans	54.31	1.00e-141	494.00
IUUC-Laf-053427	Loxodonta africana	41.75	2.00e-91	327.00
IUUC-Mcc-055571	Macaca mulatta	41.61	2.00e-93	334.00
IUUC-Meu-056083	Macropus eugenii	40.73	1.00e-83	301.00
IUUC-Mor-056978	Magnaporthe oryzae	53.47	7.00e-144	501.00
IUUC-Mpo-057410	Magnaporthe poae	43.80	2.00e-137	480.00
IUUC-Mla-058883	Melampsora laricipopulina	49.88	7.00e-111	392.00
IUUC-Mga-059353	Meleagris gallopavo	40.96	2.00e-90	323.00
IUUC-Mvi-060569	Microbotryum violaceum	46.63	6.00e-109	385.00
IUUC-Mmr-060830	Microcebus murinus	36.13	2.00e-91	327.00
IUUC-Mdo-062469	Monodelphis domestica	41.46	5.00e-90	322.00
IUUC-Mmu-064073	Mus musculus	40.63	6.00e-91	325.00
IUUC-Mpu-066824	Mustela putorius furo	37.89	6.00e-91	325.00
IUUC-Mlu-066994	Myotis lucifugus	38.53	3.00e-91	326.00
IUUC-Nfi-068476	Neosartorya fischeri	52.22	1.00e-133	468.00
IUUC-Ncr-068781	Neurospora crassa	55.68	8.00e-148	514.00
IUUC-Nle-069218	Nomascus leucogenys	36.35	9.00e-92	328.00
IUUC-Opr-071137	Ochotona princeps	36.55	7.00e-92	328.00
IUUC-Ont-072629	Oreochromis niloticus	41.28	1.00e-91	328.00
IUUC-Oan-073547	Ornithorhynchus anatinus	40.79	7.00e-89	318.00
IUUC-Ocu-074167	Oryctolagus cuniculus	36.75	7.00e-92	328.00
IUUC-Ola-086713	Oryzias latipes	41.56	7.00e-93	332.00
IUUC-Oga-088077	Otolemur garnettii	36.75	1.00e-92	331.00
IUUC-Oar-089260	Ovis aries	36.95	2.00e-91	327.00
IUUC-Ptr-090488	Pan troglodytes	36.75	1.00e-91	328.00
IUUC-Pan-091682	Papio anubis	40.88	1.00e-91	327.00
IUUC-Psi-093011	Pelodiscus sinensis	40.79	6.00e-90	322.00
IUUC-Pma-094375	Petromyzon marinus	39.18	4.00e-54	202.00
IUUC-Pno-094994	Phaeosphaeria nodorum	53.85	8.00e-139	484.00
IUUC-Pfo-097309	Poecilia formosa	39.69	2.00e-92	330.00
IUUC-Pab-097835	Pongo abelii	40.29	1.00e-88	318.00
IUUC-Pca-100411	Procavia capensis	39.45	4.00e-76	276.00
IUUC-Pva-102483	Pteropus vampyrus	40.15	9.00e-91	325.00
IUUC-Pgr-103354	Puccinia graminis	49.88	4.00e-118	416.00
IUUC-Ptt-103735	Puccinia triticina	41.10	3.00e-90	323.00
IUUC-Pte-104194	Pyrenophora teres	53.33	3.00e-140	489.00
IUUC-Pyt-104437	Pyrenophora triticirepentis	53.59	6.00e-140	488.00
IUUC-Rno-104937	Rattus norvegicus	40.44	2.00e-89	320.00
IUUC-Sce-106378	Saccharomyces cerevisiae	58.12	0.00e+00	757.00
IUUC-Sha-107210	Sarcophilus harrisii	41.22	4.00e-89	319.00
IUUC-Sja-107992	Schizosaccharomyces japonicus	54.81	8.00e-136	475.00
IUUC-Spo-108364	Schizosaccharomyces pombe	52.23	5.00e-145	505.00
IUUC-Sar-113292	Sorex araneus	41.49	8.00e-80	288.00
IUUC-Sre-114911	Sporisorium reilianum	48.37	1.00e-100	358.00
IUUC-Ssc-115348	Sus scrofa	39.80	1.00e-88	317.00
IUUC-Tgu-116597	Taeniopygia guttata	40.29	4.00e-89	319.00
IUUC-Tru-118425	Takifugu rubripes	40.98	3.00e-91	326.00
IUUC-Tsy-119223	Tarsius syrichta	35.63	6.00e-66	242.00
IUUC-Tni-120610	Tetraodon nigroviridis	41.22	8.00e-92	328.00
IUUC-Tre-122159	Trichoderma reesei	51.06	5.00e-133	465.00
IUUC-Tvi-122480	Trichoderma virens	53.40	6.00e-137	478.00
IUUC-Tme-126924	Tuber melanosporum	40.29	3.00e-132	462.00
IUUC-Tbe-127703	Tupaia belangeri	38.78	2.00e-68	250.00
IUUC-Ttr-128689	Tursiops truncatus	41.55	3.00e-89	319.00
IUUC-Uma-129489	Ustilago maydis	48.37	4.00e-108	383.00
IUUC-Vda-129792	Verticillium dahliae	52.74	9.00e-136	474.00
IUUC-Vpa-130339	Vicugna pacos	38.78	9.00e-72	261.00
IUUC-Xtr-132098	Xenopus tropicalis	39.51	3.00e-81	293.00
IUUC-Xma-133523	Xiphophorus maculatus	41.22	2.00e-92	330.00
IUUC-Yli-134440	Yarrowia lipolytica	55.22	1.00e-151	527.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence