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Tag Content
iUUCD ID IUUC-Ggo-045430
Ensembl Protein ID ENSGGOP00000000978.2
UniProt Accession G3QFB1; G3QFB1_GORGO
Protein Name Protein HIRA
Gene Name HIRA
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSGGOG00000000992.2 ENSGGOT00000000999.2 ENSGGOP00000000978.2
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 3.70e-20 71.6 69 98
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWD 29
           H + v+c+++ ++  +l+sG+dD+ i+vW 
   Q: 69   HLACVNCVRWsNSgMYLASGGDDKLIMVWK 98
           8899******955699*************7 PP
   
Organism Gorilla gorilla
Functional Description
(View)

Functional Description


     Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.
 Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.
Protein Sequence
(Fasta)
MKLLKPTWVN HNGKPIFSVD IHPDGTKFAT GGQGQDSGKV VIWNMSPVLQ EDDEKDENIP 60
KMLCQMDNHL ACVNCVRWSN SGMYLASGGD DKLIMVWKRA TYIGPSTVFG SSGKLANVEQ 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Ggo-045430|E3,WD_repeat|Gorilla gorilla
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GATGCGGCTG TGGTGGCGGC GGCGGCGGCC GAGCGCGGGT GGCGGCTGTG GCGGCGGAGG 60
GGGGCGCGGG CCGGCGATGG CGCGGCGGCC CTGAGGGCGC GGGGCGGGCG GCGGCCGGAG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Ggo-045430|E3,WD_repeat|Gorilla gorilla
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0678--Repressor
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0853--WD repeat
Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR031120--HIR1
IPR011494--Hira
IPR019015--HIRA_B_motif
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF07569--Hira
PF09453--HIRA_B
PF00400--WD40
SMART

SM00320--WD40
Gene Ontology

GO:0070062--C:extracellular exosome
GO:0000790--C:nuclear chromatin
GO:0043234--C:protein complex
GO:0016569--P:covalent chromatin modification
GO:0006336--P:DNA replication-independent nucleosome assembly
GO:0007369--P:gastrulation
GO:0042692--P:muscle cell differentiation
GO:0001649--P:osteoblast differentiation
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-001039 Aegilops tauschii 40.28 5.00e-90 325.00
IUUC-Aml-001723 Ailuropoda melanoleuca 96.62 0.00e+00 1772.00
IUUC-Atr-003132 Amborella trichopoda 41.67 1.00e-88 321.00
IUUC-Apl-003197 Anas platyrhynchos 84.49 0.00e+00 1640.00
IUUC-Aca-004733 Anolis carolinensis 82.77 0.00e+00 1610.00
IUUC-Aly-005446 Arabidopsis lyrata 35.61 2.00e-82 300.00
IUUC-Ath-007627 Arabidopsis thaliana 36.80 1.00e-85 311.00
IUUC-Ago-007766 Ashbya gossypii 31.31 6.00e-59 222.00
IUUC-Acl-008104 Aspergillus clavatus 29.52 3.00e-64 240.00
IUUC-Afl-008591 Aspergillus flavus 30.40 2.00e-65 244.00
IUUC-Afu-008781 Aspergillus fumigatus 33.33 2.00e-58 220.00
IUUC-Ani-009272 Aspergillus nidulans 28.17 1.00e-53 205.00
IUUC-Ang-009655 Aspergillus niger 33.42 4.00e-65 243.00
IUUC-Aor-010119 Aspergillus oryzae 30.40 7.00e-66 245.00
IUUC-Ate-010530 Aspergillus terreus 27.17 4.00e-56 213.00
IUUC-Ame-011147 Astyanax mexicanus 84.16 9.00e-52 194.00
IUUC-Bgr-012237 Blumeria graminis 33.50 9.00e-63 235.00
IUUC-Bta-013320 Bos taurus 90.70 0.00e+00 1749.00
IUUC-Bci-013795 Botrytis cinerea 33.92 6.00e-68 252.00
IUUC-Bdi-014075 Brachypodium distachyon 42.60 5.00e-92 332.00
IUUC-Bol-016440 Brassica oleracea 35.30 4.00e-89 322.00
IUUC-Bra-016651 Brassica rapa 40.61 4.00e-87 316.00
IUUC-Cel-018692 Caenorhabditis elegans 38.10 6.00e-76 279.00
IUUC-Cja-018987 Callithrix jacchus 98.67 0.00e+00 1736.00
IUUC-Cfa-020132 Canis familiaris 95.58 0.00e+00 1769.00
IUUC-Cpo-021484 Cavia porcellus 97.05 0.00e+00 1813.00
IUUC-Cre-022846 Chlamydomonas reinhardtii 36.20 8.00e-62 232.00
IUUC-Csa-023081 Chlorocebus sabaeus 99.31 0.00e+00 1840.00
IUUC-Cin-025182 Ciona intestinalis 55.03 8.00e-156 544.00
IUUC-Csv-026154 Ciona savignyi 55.62 8.00e-152 531.00
IUUC-Cgl-026655 Colletotrichum gloeosporioides 30.55 2.00e-66 247.00
IUUC-Cne-026891 Cryptococcus neoformans 41.08 6.00e-83 302.00
IUUC-Cme-027349 Cyanidioschyzon merolae 29.00 1.00e-51 198.00
IUUC-Dre-027655 Danio rerio 69.04 0.00e+00 1364.00
IUUC-Dno-029557 Dasypus novemcinctus 84.48 0.00e+00 1103.00
IUUC-Dor-030687 Dipodomys ordii 82.03 0.00e+00 742.00
IUUC-Dse-031334 Dothistroma septosporum 30.92 4.00e-63 236.00
IUUC-Dme-031746 Drosophila melanogaster 55.72 6.00e-159 555.00
IUUC-Ete-032384 Echinops telfairi 89.15 0.00e+00 1637.00
IUUC-Eca-033430 Equus caballus 96.12 0.00e+00 1753.00
IUUC-Fca-036121 Felis catus 95.85 0.00e+00 1770.00
IUUC-Fal-036817 Ficedula albicollis 84.27 0.00e+00 1642.00
IUUC-Fox-037906 Fusarium oxysporum 34.86 7.00e-69 254.00
IUUC-Fso-038409 Fusarium solani 33.73 1.00e-67 251.00
IUUC-Gmo-039151 Gadus morhua 86.52 0.00e+00 704.00
IUUC-Ggr-040016 Gaeumannomyces graminis 32.16 1.00e-70 261.00
IUUC-Gga-040936 Gallus gallus 85.76 0.00e+00 1730.00
IUUC-Gac-041405 Gasterosteus aculeatus 62.96 0.00e+00 1213.00
IUUC-Gma-044252 Glycine max 36.62 8.00e-91 328.00
IUUC-Hsa-046442 Homo sapiens 99.51 0.00e+00 1841.00
IUUC-Hvu-047587 Hordeum vulgare 37.69 2.00e-80 293.00
IUUC-Itr-048910 Ictidomys tridecemlineatus 99.67 2.00e-175 607.00
IUUC-Kpa-049145 Komagataella pastoris 30.88 7.00e-60 225.00
IUUC-Lch-050474 Latimeria chalumnae 76.32 0.00e+00 1436.00
IUUC-Lpe-051209 Leersia perrieri 35.53 4.00e-84 306.00
IUUC-Loc-052119 Lepisosteus oculatus 72.29 0.00e+00 1385.00
IUUC-Lma-053237 Leptosphaeria maculans 35.44 6.00e-67 249.00
IUUC-Laf-053718 Loxodonta africana 95.68 0.00e+00 1786.00
IUUC-Mcc-055621 Macaca mulatta 98.97 0.00e+00 1738.00
IUUC-Meu-055914 Macropus eugenii 78.34 0.00e+00 1476.00
IUUC-Mor-057090 Magnaporthe oryzae 33.97 8.00e-68 252.00
IUUC-Mpo-057364 Magnaporthe poae 32.58 3.00e-73 270.00
IUUC-Mtr-057744 Medicago truncatula 37.67 8.00e-92 332.00
IUUC-Mla-058914 Melampsora laricipopulina 41.40 2.00e-84 307.00
IUUC-Mga-060181 Meleagris gallopavo 83.96 0.00e+00 1672.00
IUUC-Mvi-060432 Microbotryum violaceum 37.78 8.00e-74 272.00
IUUC-Mmr-060871 Microcebus murinus 97.54 0.00e+00 1872.00
IUUC-Mdo-062301 Monodelphis domestica 86.22 0.00e+00 1637.00
IUUC-Mmu-063888 Mus musculus 95.58 0.00e+00 1777.00
IUUC-Mac-065137 Musa acuminata 38.84 9.00e-91 328.00
IUUC-Mpu-066732 Mustela putorius furo 96.22 0.00e+00 1800.00
IUUC-Mlu-067542 Myotis lucifugus 95.38 0.00e+00 1734.00
IUUC-Nfi-068396 Neosartorya fischeri 33.99 2.00e-58 220.00
IUUC-Ncr-068842 Neurospora crassa 32.46 1.00e-68 254.00
IUUC-Nle-070156 Nomascus leucogenys 99.12 0.00e+00 1848.00
IUUC-Opr-070808 Ochotona princeps 95.99 0.00e+00 1446.00
IUUC-Ont-072105 Oreochromis niloticus 67.67 0.00e+00 1338.00
IUUC-Ocu-074962 Oryctolagus cuniculus 96.92 0.00e+00 1797.00
IUUC-Oba-075178 Oryza barthii 36.78 1.00e-91 331.00
IUUC-Obr-076399 Oryza brachyantha 36.50 5.00e-92 332.00
IUUC-Ogu-078797 Oryza glumaepatula 36.78 1.00e-91 331.00
IUUC-Oin-080085 Oryza indica 35.43 1.00e-78 288.00
IUUC-Olo-081048 Oryza longistaminata 41.04 2.00e-66 247.00
IUUC-Ome-081324 Oryza meridionalis 35.87 5.00e-91 329.00
IUUC-Oni-082548 Oryza nivara 36.78 1.00e-91 331.00
IUUC-Opu-084008 Oryza punctata 42.09 3.00e-91 330.00
IUUC-Oru-084339 Oryza rufipogon 36.59 4.00e-91 329.00
IUUC-Osa-085782 Oryza sativa 36.59 4.00e-91 329.00
IUUC-Ola-087302 Oryzias latipes 68.79 0.00e+00 813.00
IUUC-Olu-087611 Ostreococcus lucimarinus 36.05 1.00e-89 324.00
IUUC-Oga-087935 Otolemur garnettii 97.12 0.00e+00 1770.00
IUUC-Oar-089229 Ovis aries 70.07 0.00e+00 1057.00
IUUC-Ptr-090715 Pan troglodytes 99.61 0.00e+00 1843.00
IUUC-Pan-092318 Papio anubis 99.30 0.00e+00 1814.00
IUUC-Psi-094053 Pelodiscus sinensis 84.03 0.00e+00 1655.00
IUUC-Pno-094985 Phaeosphaeria nodorum 32.60 7.00e-59 222.00
IUUC-Ppa-095819 Physcomitrella patens 39.80 5.00e-89 322.00
IUUC-Pfo-096857 Poecilia formosa 66.54 0.00e+00 1290.00
IUUC-Pab-098047 Pongo abelii 99.61 0.00e+00 1845.00
IUUC-Pop-099587 Populus trichocarpa 39.55 6.00e-90 325.00
IUUC-Pca-100558 Procavia capensis 95.31 0.00e+00 749.00
IUUC-Ppe-101261 Prunus persica 38.27 3.00e-91 330.00
IUUC-Pva-102683 Pteropus vampyrus 95.97 0.00e+00 1794.00
IUUC-Pgr-103660 Puccinia graminis 40.88 1.00e-77 284.00
IUUC-Ptt-103900 Puccinia triticina 41.83 2.00e-79 290.00
IUUC-Pte-104209 Pyrenophora teres 34.27 3.00e-65 243.00
IUUC-Pyt-104802 Pyrenophora triticirepentis 31.37 5.00e-65 243.00
IUUC-Rno-105566 Rattus norvegicus 95.38 0.00e+00 1802.00
IUUC-Sce-106291 Saccharomyces cerevisiae 32.59 4.00e-61 229.00
IUUC-Sha-107514 Sarcophilus harrisii 80.70 0.00e+00 1516.00
IUUC-Sja-107833 Schizosaccharomyces japonicus 34.62 2.00e-81 297.00
IUUC-Spo-108162 Schizosaccharomyces pombe 36.36 1.00e-77 285.00
IUUC-Smo-109533 Selaginella moellendorffii 37.22 5.00e-92 332.00
IUUC-Sit-109980 Setaria italica 37.77 7.00e-93 335.00
IUUC-Sly-111547 Solanum lycopersicum 37.95 1.00e-92 334.00
IUUC-Stu-112705 Solanum tuberosum 38.15 5.00e-93 335.00
IUUC-Sar-113222 Sorex araneus 89.87 0.00e+00 1545.00
IUUC-Sbi-114272 Sorghum bicolor 37.88 2.00e-93 337.00
IUUC-Sre-115061 Sporisorium reilianum 27.45 2.00e-94 340.00
IUUC-Ssc-116364 Sus scrofa 94.54 0.00e+00 1844.00
IUUC-Tgu-116645 Taeniopygia guttata 84.47 0.00e+00 1668.00
IUUC-Tru-117590 Takifugu rubripes 66.48 0.00e+00 1305.00
IUUC-Tsy-119212 Tarsius syrichta 91.70 0.00e+00 1003.00
IUUC-Tni-119915 Tetraodon nigroviridis 66.67 0.00e+00 1286.00
IUUC-Tca-121765 Theobroma cacao 37.72 4.00e-91 329.00
IUUC-Tre-121887 Trichoderma reesei 33.90 8.00e-61 229.00
IUUC-Tvi-122262 Trichoderma virens 33.90 9.00e-61 228.00
IUUC-Tae-124148 Triticum aestivum 45.36 4.00e-39 156.00
IUUC-Tur-126483 Triticum urartu 38.89 5.00e-94 339.00
IUUC-Tme-127202 Tuber melanosporum 30.72 4.00e-57 216.00
IUUC-Tbe-127350 Tupaia belangeri 82.93 0.00e+00 641.00
IUUC-Ttr-129077 Tursiops truncatus 90.85 0.00e+00 1774.00
IUUC-Uma-129465 Ustilago maydis 35.91 4.00e-79 289.00
IUUC-Vda-129844 Verticillium dahliae 34.56 1.00e-66 248.00
IUUC-Vvi-131397 Vitis vinifera 37.40 2.00e-92 333.00
IUUC-Xtr-132057 Xenopus tropicalis 76.10 0.00e+00 1438.00
IUUC-Xma-134139 Xiphophorus maculatus 67.46 0.00e+00 801.00
IUUC-Yli-134424 Yarrowia lipolytica 31.94 5.00e-66 246.00
IUUC-Zma-135839 Zea mays 37.52 3.00e-92 333.00
Created Date 25-Jun-2017

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