iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aml-001778

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ACTA01064721

Gene Name

UBE2D2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000011216.1	ENSAMET00000012296.1	ENSAMEP00000011798.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	1.00e-55	187.4	4	135
UBD/UBC-like/UBD_UBC	5.40e-84	279.3	4	138

Active Site

Position(s)	Description	Evidence
81	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 4    kelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkeeekW 92
           kel++l++dpp+++sa+pv + d+++w+++i+Gp+d+pY+ggvF l+i+fp+dYPfkPPkv f+t+i+hPn+++nG++Cl+il+  ++W
   Q: 4    KELNDLARDPPAQCSAGPVGD-DMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILR--SQW 89
           8********************.9************************************************************9..*** PP
   S: 93   spalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           spal++++vllsi+sll++pnp++pl  e+a+++k++re+y++++r
   Q: 90   SPALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDREKYNRIAR 135
           ******************************************9987 PP

UBD/UBC-like/UBD_UBC

   S: 4    kelkdllrdeeaqisadlvdddlfelratiagppdspyeggvffltiklptdypfkppkvafitkiyhpninsngsicldilrsqwsaa 92
           kel+dl+rd++aq+sa++v+dd+f+++ati+gp+dspy+ggvfflti++ptdypfkppkvaf+t+iyhpninsngsicldilrsqws+a
   Q: 4    KELNDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPA 92
           8**************************************************************************************** PP
   S: 93   ltlskvllslcslladaepddplvaeiariyktdkekykriarewt 138
           lt+skvlls+csll+d++pddplv+eiariyktd+eky+riarewt
   Q: 93   LTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDREKYNRIAREWT 138
           *********************************************8 PP

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

CFLKELNDLA RDPPAQCSAG PVGDDMFHWQ ATIMGPNDSP YQGGVFFLTI HFPTDYPFKP 60
PKVAFTTRIY HPNINSNGSI CLDILRSQWS PALTISKVLL SICSLLCDPN PDDPLVPEIA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGTTTTCTTA AGGAATTGAA TGACCTGGCA CGGGACCCCC CAGCACAGTG TTCAGCAGGT 60
CCTGTTGGAG ATGATAGTAA GTATTTAAAG GGAATGATGG AGTAAAACTG CATAACCATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0043234--C:protein complex
GO:0000151--C:ubiquitin ligase complex
GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0051865--P:protein autoubiquitination
GO:0070936--P:protein K48-linked ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Atr-002861	Amborella trichopoda	80.99	2.00e-68	250.00
IUUC-Apl-003199	Anas platyrhynchos	100.00	7.00e-81	291.00
IUUC-Aca-005236	Anolis carolinensis	100.00	1.00e-81	294.00
IUUC-Aly-006364	Arabidopsis lyrata	80.28	2.00e-68	251.00
IUUC-Afl-008709	Aspergillus flavus	80.00	7.00e-68	251.00
IUUC-Ang-009725	Aspergillus niger	84.80	6.00e-62	229.00
IUUC-Ame-011831	Astyanax mexicanus	97.14	1.00e-79	287.00
IUUC-Bgr-012238	Blumeria graminis	79.58	5.00e-67	246.00
IUUC-Bta-013158	Bos taurus	100.00	1.00e-81	294.00
IUUC-Cja-019886	Callithrix jacchus	100.00	1.00e-81	294.00
IUUC-Cfa-020436	Canis familiaris	100.00	1.00e-81	294.00
IUUC-Cpo-021714	Cavia porcellus	97.86	7.00e-80	288.00
IUUC-Csa-023148	Chlorocebus sabaeus	95.74	5.00e-77	279.00
IUUC-Dre-027758	Danio rerio	98.57	2.00e-80	290.00
IUUC-Dno-028952	Dasypus novemcinctus	100.00	1.00e-82	298.00
IUUC-Dor-030285	Dipodomys ordii	97.84	2.00e-79	287.00
IUUC-Ete-032295	Echinops telfairi	100.00	7.00e-81	291.00
IUUC-Eca-033293	Equus caballus	100.00	4.00e-81	293.00
IUUC-Eeu-034766	Erinaceus europaeus	96.43	6.00e-78	281.00
IUUC-Fca-035917	Felis catus	97.86	3.00e-80	290.00
IUUC-Fal-036904	Ficedula albicollis	97.86	4.00e-80	289.00
IUUC-Gmo-038898	Gadus morhua	97.79	1.00e-77	281.00
IUUC-Ggr-039912	Gaeumannomyces graminis	79.31	8.00e-66	241.00
IUUC-Gga-040758	Gallus gallus	100.00	1.00e-81	294.00
IUUC-Gac-042231	Gasterosteus aculeatus	97.14	2.00e-79	287.00
IUUC-Ggo-045375	Gorilla gorilla	99.29	3.00e-81	293.00
IUUC-Hsa-045885	Homo sapiens	100.00	1.00e-81	294.00
IUUC-Hvu-047546	Hordeum vulgare	78.17	5.00e-67	246.00
IUUC-Itr-048882	Ictidomys tridecemlineatus	100.00	1.00e-81	294.00
IUUC-Lpe-050972	Leersia perrieri	80.28	2.00e-68	251.00
IUUC-Loc-052788	Lepisosteus oculatus	97.18	5.00e-81	292.00
IUUC-Laf-053580	Loxodonta africana	100.00	2.00e-81	293.00
IUUC-Mcc-054673	Macaca mulatta	100.00	4.00e-81	292.00
IUUC-Meu-056462	Macropus eugenii	96.40	2.00e-78	283.00
IUUC-Mpo-057596	Magnaporthe poae	79.31	2.00e-65	241.00
IUUC-Mtr-058257	Medicago truncatula	80.28	8.00e-68	248.00
IUUC-Mga-059237	Meleagris gallopavo	97.86	5.00e-80	289.00
IUUC-Mmr-061474	Microcebus murinus	98.58	3.00e-81	293.00
IUUC-Mdo-062962	Monodelphis domestica	100.00	1.00e-81	294.00
IUUC-Mmu-063518	Mus musculus	100.00	1.00e-81	294.00
IUUC-Mpu-066604	Mustela putorius furo	100.00	3.00e-81	293.00
IUUC-Nle-069800	Nomascus leucogenys	98.57	1.00e-78	284.00
IUUC-Opr-070191	Ochotona princeps	97.84	2.00e-79	287.00
IUUC-Ont-071766	Oreochromis niloticus	98.57	1.00e-80	291.00
IUUC-Oan-073026	Ornithorhynchus anatinus	92.86	5.00e-77	279.00
IUUC-Ocu-074315	Oryctolagus cuniculus	100.00	1.00e-81	294.00
IUUC-Oba-075411	Oryza barthii	80.28	3.00e-68	250.00
IUUC-Obr-076658	Oryza brachyantha	80.28	2.00e-68	251.00
IUUC-Ogl-077124	Oryza glaberrima	80.28	2.00e-68	251.00
IUUC-Ogu-078981	Oryza glumaepatula	80.28	3.00e-68	250.00
IUUC-Oin-080092	Oryza indica	80.28	2.00e-68	251.00
IUUC-Olo-080786	Oryza longistaminata	80.28	3.00e-68	250.00
IUUC-Ome-081987	Oryza meridionalis	79.58	9.00e-68	248.00
IUUC-Opu-083833	Oryza punctata	80.28	2.00e-68	251.00
IUUC-Ola-086331	Oryzias latipes	98.57	1.00e-80	291.00
IUUC-Olu-087615	Ostreococcus lucimarinus	76.06	2.00e-63	233.00
IUUC-Oga-088477	Otolemur garnettii	96.43	1.00e-79	288.00
IUUC-Oar-090038	Ovis aries	97.86	3.00e-80	290.00
IUUC-Ptr-090707	Pan troglodytes	100.00	1.00e-81	294.00
IUUC-Pan-092143	Papio anubis	100.00	1.00e-81	294.00
IUUC-Psi-094076	Pelodiscus sinensis	97.86	3.00e-80	290.00
IUUC-Pma-094405	Petromyzon marinus	95.49	4.00e-74	269.00
IUUC-Pfo-096753	Poecilia formosa	98.57	1.00e-80	291.00
IUUC-Pab-097764	Pongo abelii	100.00	1.00e-81	294.00
IUUC-Pop-099853	Populus trichocarpa	80.99	3.00e-68	250.00
IUUC-Ptt-103723	Puccinia triticina	77.86	3.00e-61	226.00
IUUC-Rno-105498	Rattus norvegicus	97.86	3.00e-80	290.00
IUUC-Sit-109936	Setaria italica	79.58	1.00e-68	252.00
IUUC-Stu-112629	Solanum tuberosum	80.99	9.00e-69	251.00
IUUC-Sar-113302	Sorex araneus	100.00	7.00e-81	291.00
IUUC-Ssc-116154	Sus scrofa	97.86	3.00e-80	289.00
IUUC-Tgu-116727	Taeniopygia guttata	97.86	3.00e-80	290.00
IUUC-Tru-118272	Takifugu rubripes	98.57	4.00e-80	289.00
IUUC-Tsy-119491	Tarsius syrichta	97.12	3.00e-76	278.00
IUUC-Tni-120056	Tetraodon nigroviridis	98.57	4.00e-80	289.00
IUUC-Tbe-127609	Tupaia belangeri	100.00	2.00e-67	246.00
IUUC-Vpa-130446	Vicugna pacos	99.29	4.00e-80	290.00
IUUC-Xtr-132329	Xenopus tropicalis	100.00	1.00e-81	294.00
IUUC-Xma-133829	Xiphophorus maculatus	98.57	1.00e-80	291.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence