iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ppa-095536

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Eukaryotic translation initiation factor 3 subunit I

Genbank Nucleotide ID

DS544923

Gene Name

PHYPADRAFT_161649

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
PP1S34_388V6	PP1S34_388V6.1	PP1S34_388V6.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.80e-28	96.5	50	88
UBD/Beta-Prp	3.30e-44	152.0	97	315

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gH++ v+c++   d t+lv++s D t+k+WD  tgvll 
   Q: 50   GHNGAVWCCDVsRDsTRLVTSSADQTVKLWDCETGVLLD 88
           8***********777********************9986 PP

UBD/Beta-Prp

   S: 56   tavkfspdgkilvtgseD......rtikvw......dlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee..tlsgh 136
           +av+fs+ +  +v  s+D       +i+v       +l++++ v t++g + ++  + + p +++++s+++d tir+wd etg+cl e  +++gh
   Q: 97   RAVSFSEGD-KMVVISTDpfmekqSAIHVKminsdrSLQSSEDVLTITGPQGRINRVMWGPLNKTIISAGEDATIRIWDAETGKCLIEsdPETGH 190
           678888886.78888888899988666665555888888***********************************************9999***** PP
   S: 137  dgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgs..ldgtvklwdlqtgec............vrt 217
           ++v+++++ + dg+ +++Gs D+  +lWd++t ++l+t t   +++v+  ++++   ++v g+  + ++v++ + ++g+             +  
   Q: 191  QKVITSMAKSADGSHFITGSQDKSAKLWDIRTLTVLKTYTT--ERPVNAAAISPLLDHVVIGGgqEASQVTMTSTRAGKFeakffhkifeeeIGG 283
           ***************************************86..9**********9999887651166899999**98888888899999988999 PP
   S: 218  lnghtdnvksvrfspnderlvsgssDgsiriW 249
           ++gh  +++ ++f p++  + sg++Dg +r++
   Q: 284  VKGHFGPINALAFNPDGRSFSSGGEDGYVRVH 315
           ******************************97 PP

Organism

Physcomitrella patens

Functional Description
(View)

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

Protein Sequence
(Fasta)

MRPILLKGHE RPLTFLKYNR DGDLLFSCAK DHTPTVWYAS NGERLGTYRG HNGAVWCCDV 60
SRDSTRLVTS SADQTVKLWD CETGVLLDTF YFDAPARAVS FSEGDKMVVI STDPFMEKQS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTCTTCCCTG AGAAACCCTA ATTCCAGATT GCTGTGCTTG CACGCCTGGG AGCTTCGTGA 60
GCTTCGTGAG GATCTGAGGT GTGCGAGCGC ATCGAATTCC AGTTGGGCTA GGCGTGATTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0396--Initiation factor
KW-0648--Protein biosynthesis
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR027525--eIF3i
IPR020472--G-protein_beta_WD-40_rep
IPR002469--Peptidase_S9B_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0016282--C:eukaryotic 43S preinitiation complex
GO:0033290--C:eukaryotic 48S preinitiation complex
GO:0005852--C:eukaryotic translation initiation factor 3 complex
GO:0003743--F:translation initiation factor activity
GO:0001731--P:formation of translation preinitiation complex
GO:0006446--P:regulation of translational initiation

KEGG

ppp:PHYPADRAFT_161649

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000115	Aegilops tauschii	80.83	7.00e-54	203.00
IUUC-Aml-001321	Ailuropoda melanoleuca	49.07	3.00e-91	327.00
IUUC-Atr-002468	Amborella trichopoda	78.76	8.00e-91	325.00
IUUC-Apl-003841	Anas platyrhynchos	49.69	4.00e-92	330.00
IUUC-Aca-005123	Anolis carolinensis	48.92	9.00e-93	332.00
IUUC-Acl-008098	Aspergillus clavatus	47.27	4.00e-80	290.00
IUUC-Afl-008494	Aspergillus flavus	47.37	2.00e-83	301.00
IUUC-Afu-009080	Aspergillus fumigatus	46.50	2.00e-80	291.00
IUUC-Ani-009230	Aspergillus nidulans	48.00	2.00e-82	298.00
IUUC-Aor-010114	Aspergillus oryzae	47.37	2.00e-83	301.00
IUUC-Bgr-012121	Blumeria graminis	45.82	6.00e-78	283.00
IUUC-Bta-013143	Bos taurus	49.23	6.00e-92	329.00
IUUC-Bci-013950	Botrytis cinerea	48.61	3.00e-86	310.00
IUUC-Bra-017760	Brassica rapa	71.82	2.00e-145	508.00
IUUC-Cel-018226	Caenorhabditis elegans	42.06	7.00e-75	273.00
IUUC-Cja-019741	Callithrix jacchus	48.92	1.00e-91	328.00
IUUC-Cfa-021204	Canis familiaris	48.77	6.00e-91	326.00
IUUC-Cpo-021661	Cavia porcellus	48.77	4.00e-91	327.00
IUUC-Cre-022952	Chlamydomonas reinhardtii	52.31	3.00e-100	357.00
IUUC-Csa-024038	Chlorocebus sabaeus	48.92	1.00e-91	328.00
IUUC-Cin-025597	Ciona intestinalis	49.70	3.00e-91	327.00
IUUC-Cgl-026583	Colletotrichum gloeosporioides	47.99	8.00e-82	296.00
IUUC-Cne-026838	Cryptococcus neoformans	45.59	3.00e-82	297.00
IUUC-Dno-029171	Dasypus novemcinctus	49.07	1.00e-90	326.00
IUUC-Dse-031191	Dothistroma septosporum	45.73	1.00e-81	295.00
IUUC-Dme-031879	Drosophila melanogaster	50.62	5.00e-98	349.00
IUUC-Ete-032336	Echinops telfairi	42.58	9.00e-46	175.00
IUUC-Eca-033259	Equus caballus	48.77	7.00e-91	326.00
IUUC-Eeu-035153	Erinaceus europaeus	44.85	3.00e-27	115.00
IUUC-Fca-036489	Felis catus	48.77	7.00e-91	326.00
IUUC-Fal-037485	Ficedula albicollis	49.38	7.00e-92	329.00
IUUC-Fox-037860	Fusarium oxysporum	47.68	9.00e-84	302.00
IUUC-Fso-038188	Fusarium solani	46.75	7.00e-82	296.00
IUUC-Ggr-040045	Gaeumannomyces graminis	47.68	4.00e-82	297.00
IUUC-Gga-040645	Gallus gallus	48.65	1.00e-90	325.00
IUUC-Ggo-045578	Gorilla gorilla	48.92	1.00e-91	328.00
IUUC-Hsa-046734	Homo sapiens	48.92	1.00e-91	328.00
IUUC-Hvu-047553	Hordeum vulgare	74.54	4.00e-146	509.00
IUUC-Itr-048467	Ictidomys tridecemlineatus	48.77	8.00e-91	325.00
IUUC-Lpe-051338	Leersia perrieri	76.53	2.00e-144	504.00
IUUC-Loc-052094	Lepisosteus oculatus	43.93	6.00e-77	280.00
IUUC-Laf-053801	Loxodonta africana	48.74	3.00e-88	317.00
IUUC-Mcc-055498	Macaca mulatta	43.69	4.00e-72	263.00
IUUC-Meu-056729	Macropus eugenii	45.09	2.00e-81	294.00
IUUC-Mtr-058051	Medicago truncatula	77.61	9.00e-155	538.00
IUUC-Mla-059061	Melampsora laricipopulina	47.02	2.00e-82	298.00
IUUC-Mga-059229	Meleagris gallopavo	49.08	1.00e-89	322.00
IUUC-Mvi-060399	Microbotryum violaceum	44.05	2.00e-78	285.00
IUUC-Mmr-060764	Microcebus murinus	49.23	3.00e-92	330.00
IUUC-Mdo-062088	Monodelphis domestica	48.62	3.00e-91	327.00
IUUC-Mmu-064304	Mus musculus	48.92	7.00e-92	329.00
IUUC-Mpu-066340	Mustela putorius furo	48.77	7.00e-91	326.00
IUUC-Mlu-067111	Myotis lucifugus	49.07	2.00e-91	328.00
IUUC-Nfi-068478	Neosartorya fischeri	46.20	2.00e-79	288.00
IUUC-Nle-069903	Nomascus leucogenys	48.77	1.00e-90	325.00
IUUC-Opr-070221	Ochotona princeps	48.00	2.00e-89	321.00
IUUC-Oan-073660	Ornithorhynchus anatinus	46.92	6.00e-77	280.00
IUUC-Ocu-074039	Oryctolagus cuniculus	48.77	5.00e-91	327.00
IUUC-Ogu-078207	Oryza glumaepatula	75.38	4.00e-149	519.00
IUUC-Oni-082411	Oryza nivara	67.48	2.00e-129	454.00
IUUC-Opu-083136	Oryza punctata	76.07	5.00e-151	526.00
IUUC-Oru-084916	Oryza rufipogon	73.43	1.00e-147	514.00
IUUC-Olu-087602	Ostreococcus lucimarinus	63.69	7.00e-124	436.00
IUUC-Oga-088154	Otolemur garnettii	48.77	2.00e-91	327.00
IUUC-Oar-089915	Ovis aries	49.07	4.00e-91	327.00
IUUC-Pan-092035	Papio anubis	48.92	1.00e-91	328.00
IUUC-Psi-094096	Pelodiscus sinensis	47.00	2.00e-54	204.00
IUUC-Pab-097726	Pongo abelii	48.92	1.00e-91	328.00
IUUC-Pca-101014	Procavia capensis	49.23	4.00e-92	330.00
IUUC-Pva-102789	Pteropus vampyrus	45.54	2.00e-80	291.00
IUUC-Pgr-103479	Puccinia graminis	45.09	2.00e-81	295.00
IUUC-Ptt-103981	Puccinia triticina	44.17	3.00e-81	294.00
IUUC-Rno-105867	Rattus norvegicus	44.38	7.00e-76	276.00
IUUC-Sce-106251	Saccharomyces cerevisiae	43.07	4.00e-75	274.00
IUUC-Sha-107039	Sarcophilus harrisii	48.62	3.00e-91	327.00
IUUC-Spo-108314	Schizosaccharomyces pombe	45.71	1.00e-84	305.00
IUUC-Ssl-108478	Sclerotinia sclerotiorum	47.99	2.00e-85	308.00
IUUC-Sit-110801	Setaria italica	74.23	1.00e-146	511.00
IUUC-Sly-111326	Solanum lycopersicum	76.99	3.00e-154	536.00
IUUC-Stu-112458	Solanum tuberosum	78.22	3.00e-155	540.00
IUUC-Sre-115096	Sporisorium reilianum	43.92	2.00e-76	278.00
IUUC-Ssc-116080	Sus scrofa	49.23	6.00e-92	329.00
IUUC-Tgu-116988	Taeniopygia guttata	49.38	7.00e-92	329.00
IUUC-Tca-121316	Theobroma cacao	77.61	7.00e-156	542.00
IUUC-Tre-122097	Trichoderma reesei	47.99	1.00e-82	299.00
IUUC-Tvi-122442	Trichoderma virens	47.68	1.00e-82	298.00
IUUC-Tme-127038	Tuber melanosporum	47.99	3.00e-85	307.00
IUUC-Ttr-128659	Tursiops truncatus	45.54	3.00e-71	261.00
IUUC-Uma-129464	Ustilago maydis	44.81	5.00e-77	280.00
IUUC-Vda-129841	Verticillium dahliae	49.54	1.00e-84	305.00
IUUC-Xtr-132395	Xenopus tropicalis	50.62	2.00e-93	334.00
IUUC-Zma-135904	Zea mays	73.01	1.00e-145	508.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence