iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aca-004304

Ensembl Protein ID

ENSACAP00000008123.3

UniProt Accession

H9GDQ5; H9GDQ5_ANOCA

Protein Name

DNA repair protein REV1

Gene Name

REV1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000008218.3	ENSACAT00000008295.3	ENSACAP00000008123.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBM	7.80e-20	69.8	1010	1038

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBM

   S: 1    lPsqvDpeVfsqLPeeiQeEvmaelrqqk 29
           ++sqvDpeVf++LP e+QeE++++++q +
   Q: 1010 AFSQVDPEVFAALPSELQEELRQAYDQKQ 1038
           59************************987 PP

Organism

Anolis carolinensis

Functional Description
(View)

Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents.

Protein Sequence
(Fasta)

MKQGGWRKRA NDRDGWGAWG GYMSAKVQKL EDQFRSDAAM QLQKDGTSSG IFSGVAIYVN 60
GYTDPSSDEL RHLMMLHGGQ YHVYYSRSKT THIIATNLPN AKIKELKGEK VVRPEWITDS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGGGTCTATA TATAGCACTC CCTCAGTGCG GCGGCGACGG CGGATGGGCT AGCCCTCTTT 60
CGCGACTGGG GAGATCAAGC AGTGTTGCCA CGACGCCGCC GCCGCCGCTT CTCTCCCTCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0227--DNA damage
KW-0234--DNA repair
KW-0237--DNA synthesis
KW-0238--DNA-binding
KW-0548--Nucleotidyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0808--Transferase

Interpro

IPR001357--BRCT_dom
IPR017961--DNA_pol_Y-fam_little_finger
IPR025527--DUF4414
IPR012112--REV1
IPR031991--Rev1_C
IPR001126--UmuC

PROSITE

PS50172--BRCT
PS50173--UMUC

Pfam

PF16589--BRCT_2
PF14377--DUF4414
PF00817--IMS
PF11799--IMS_C
PF16727--REV1_C

SMART

SM00292--BRCT

Gene Ontology

GO:0005634--C:nucleus
GO:0003684--F:damaged DNA binding
GO:0017125--F:deoxycytidyl transferase activity
GO:0042276--P:error-prone translesion synthesis
GO:0009411--P:response to UV

KEGG

acs:100553599

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000375	Aegilops tauschii	29.50	2.00e-33	137.00
IUUC-Aml-001185	Ailuropoda melanoleuca	68.28	0.00e+00	1613.00
IUUC-Atr-002915	Amborella trichopoda	33.44	1.00e-85	311.00
IUUC-Apl-004054	Anas platyrhynchos	71.56	0.00e+00	1685.00
IUUC-Aly-005696	Arabidopsis lyrata	34.66	8.00e-83	301.00
IUUC-Ath-006893	Arabidopsis thaliana	33.28	5.00e-86	312.00
IUUC-Ago-007722	Ashbya gossypii	27.79	1.00e-39	158.00
IUUC-Acl-008347	Aspergillus clavatus	34.26	3.00e-89	323.00
IUUC-Afl-008444	Aspergillus flavus	33.55	2.00e-85	310.00
IUUC-Afu-008837	Aspergillus fumigatus	29.49	2.00e-104	374.00
IUUC-Ani-009188	Aspergillus nidulans	36.58	2.00e-88	321.00
IUUC-Ang-009866	Aspergillus niger	34.52	1.00e-93	338.00
IUUC-Aor-010107	Aspergillus oryzae	33.55	1.00e-85	311.00
IUUC-Ate-010359	Aspergillus terreus	32.59	5.00e-92	332.00
IUUC-Ame-010664	Astyanax mexicanus	50.45	0.00e+00	1142.00
IUUC-Bgr-012244	Blumeria graminis	27.68	3.00e-81	296.00
IUUC-Bta-013405	Bos taurus	65.26	0.00e+00	1392.00
IUUC-Bci-013849	Botrytis cinerea	29.91	5.00e-91	329.00
IUUC-Bdi-014066	Brachypodium distachyon	36.92	1.00e-85	311.00
IUUC-Bol-015544	Brassica oleracea	36.67	2.00e-86	314.00
IUUC-Bra-017792	Brassica rapa	32.96	2.00e-84	307.00
IUUC-Cel-018148	Caenorhabditis elegans	34.82	2.00e-83	303.00
IUUC-Cja-019742	Callithrix jacchus	57.34	0.00e+00	1098.00
IUUC-Cfa-020112	Canis familiaris	69.07	0.00e+00	1625.00
IUUC-Cpo-022152	Cavia porcellus	67.06	0.00e+00	1618.00
IUUC-Cre-022951	Chlamydomonas reinhardtii	30.57	4.00e-51	196.00
IUUC-Csa-023504	Chlorocebus sabaeus	68.76	0.00e+00	1620.00
IUUC-Cho-024780	Choloepus hoffmanni	63.19	9.00e-155	541.00
IUUC-Cin-025276	Ciona intestinalis	40.49	1.00e-107	383.00
IUUC-Csv-026283	Ciona savignyi	43.47	3.00e-112	399.00
IUUC-Cgl-026726	Colletotrichum gloeosporioides	26.34	4.00e-102	366.00
IUUC-Cne-027079	Cryptococcus neoformans	33.40	2.00e-78	287.00
IUUC-Cme-027346	Cyanidioschyzon merolae	28.73	2.00e-49	191.00
IUUC-Dre-028073	Danio rerio	49.70	0.00e+00	1110.00
IUUC-Dno-030038	Dasypus novemcinctus	66.93	0.00e+00	1608.00
IUUC-Dor-031100	Dipodomys ordii	64.99	0.00e+00	1153.00
IUUC-Dse-031310	Dothistroma septosporum	27.28	7.00e-99	355.00
IUUC-Dme-031991	Drosophila melanogaster	43.90	3.00e-113	402.00
IUUC-Ete-033082	Echinops telfairi	62.88	0.00e+00	1103.00
IUUC-Eca-033471	Equus caballus	68.75	0.00e+00	1621.00
IUUC-Eeu-034993	Erinaceus europaeus	68.71	0.00e+00	1103.00
IUUC-Fca-035367	Felis catus	68.42	0.00e+00	1559.00
IUUC-Fal-036973	Ficedula albicollis	69.94	0.00e+00	1591.00
IUUC-Fox-037677	Fusarium oxysporum	30.17	1.00e-87	317.00
IUUC-Fso-038252	Fusarium solani	29.92	2.00e-86	313.00
IUUC-Gmo-039669	Gadus morhua	50.76	0.00e+00	825.00
IUUC-Ggr-039988	Gaeumannomyces graminis	27.09	6.00e-99	355.00
IUUC-Gga-040423	Gallus gallus	70.62	0.00e+00	1650.00
IUUC-Gac-042134	Gasterosteus aculeatus	47.09	0.00e+00	1001.00
IUUC-Gma-042929	Glycine max	32.50	3.00e-114	406.00
IUUC-Ggo-044528	Gorilla gorilla	68.76	0.00e+00	1625.00
IUUC-Hsa-046259	Homo sapiens	69.00	0.00e+00	1607.00
IUUC-Hvu-047139	Hordeum vulgare	30.07	5.00e-58	218.00
IUUC-Itr-048621	Ictidomys tridecemlineatus	69.23	0.00e+00	1635.00
IUUC-Kpa-049169	Komagataella pastoris	28.83	2.00e-62	234.00
IUUC-Lch-050471	Latimeria chalumnae	63.05	0.00e+00	1486.00
IUUC-Lpe-050800	Leersia perrieri	29.43	7.00e-91	328.00
IUUC-Loc-052320	Lepisosteus oculatus	47.07	0.00e+00	921.00
IUUC-Lma-053149	Leptosphaeria maculans	29.34	1.00e-86	314.00
IUUC-Laf-053810	Loxodonta africana	67.03	0.00e+00	1519.00
IUUC-Mcc-055574	Macaca mulatta	68.68	0.00e+00	1594.00
IUUC-Meu-055945	Macropus eugenii	54.05	0.00e+00	896.00
IUUC-Mor-057195	Magnaporthe oryzae	30.43	9.00e-90	325.00
IUUC-Mpo-057488	Magnaporthe poae	30.25	5.00e-86	312.00
IUUC-Mtr-057955	Medicago truncatula	35.71	2.00e-87	317.00
IUUC-Mla-059027	Melampsora laricipopulina	35.49	2.00e-77	283.00
IUUC-Mga-060156	Meleagris gallopavo	71.35	0.00e+00	1677.00
IUUC-Mvi-060398	Microbotryum violaceum	34.41	3.00e-77	283.00
IUUC-Mmr-061113	Microcebus murinus	69.52	0.00e+00	1611.00
IUUC-Mdo-063001	Monodelphis domestica	70.73	0.00e+00	1678.00
IUUC-Mmu-063180	Mus musculus	67.17	0.00e+00	1580.00
IUUC-Mac-065551	Musa acuminata	40.38	5.00e-54	205.00
IUUC-Mpu-066525	Mustela putorius furo	69.41	0.00e+00	1622.00
IUUC-Mlu-067877	Myotis lucifugus	68.62	0.00e+00	1597.00
IUUC-Nfi-068418	Neosartorya fischeri	31.72	3.00e-89	323.00
IUUC-Ncr-068648	Neurospora crassa	30.57	7.00e-89	322.00
IUUC-Nle-069959	Nomascus leucogenys	68.68	0.00e+00	1610.00
IUUC-Opr-070522	Ochotona princeps	67.12	0.00e+00	962.00
IUUC-Ont-072293	Oreochromis niloticus	47.33	0.00e+00	833.00
IUUC-Oan-073519	Ornithorhynchus anatinus	68.01	0.00e+00	1638.00
IUUC-Ocu-074492	Oryctolagus cuniculus	66.30	0.00e+00	1489.00
IUUC-Oba-075567	Oryza barthii	29.86	1.00e-92	334.00
IUUC-Obr-076332	Oryza brachyantha	37.27	2.00e-86	313.00
IUUC-Ogl-077348	Oryza glaberrima	30.00	8.00e-94	338.00
IUUC-Ogu-078779	Oryza glumaepatula	29.74	5.00e-92	332.00
IUUC-Oin-079738	Oryza indica	28.06	1.00e-81	298.00
IUUC-Olo-080701	Oryza longistaminata	28.24	7.00e-82	298.00
IUUC-Ome-081708	Oryza meridionalis	30.32	9.00e-91	328.00
IUUC-Oni-082251	Oryza nivara	29.33	2.00e-89	323.00
IUUC-Opu-083528	Oryza punctata	29.74	8.00e-85	308.00
IUUC-Oru-084293	Oryza rufipogon	29.30	1.00e-87	318.00
IUUC-Osa-085549	Oryza sativa	30.00	2.00e-93	337.00
IUUC-Ola-086793	Oryzias latipes	47.08	0.00e+00	1040.00
IUUC-Olu-087786	Ostreococcus lucimarinus	29.40	7.00e-58	218.00
IUUC-Oga-089006	Otolemur garnettii	68.62	0.00e+00	1599.00
IUUC-Oar-089597	Ovis aries	66.14	0.00e+00	1540.00
IUUC-Ptr-091520	Pan troglodytes	68.84	0.00e+00	1603.00
IUUC-Pan-092333	Papio anubis	68.92	0.00e+00	1586.00
IUUC-Psi-094004	Pelodiscus sinensis	72.44	0.00e+00	1733.00
IUUC-Pma-094128	Petromyzon marinus	50.96	4.00e-93	335.00
IUUC-Pno-094849	Phaeosphaeria nodorum	28.36	1.00e-80	294.00
IUUC-Ppa-095714	Physcomitrella patens	32.55	5.00e-96	345.00
IUUC-Pfo-096569	Poecilia formosa	51.18	0.00e+00	828.00
IUUC-Pab-097960	Pongo abelii	68.84	0.00e+00	1602.00
IUUC-Pop-098921	Populus trichocarpa	32.14	4.00e-83	303.00
IUUC-Pca-100509	Procavia capensis	58.04	0.00e+00	770.00
IUUC-Ppe-101730	Prunus persica	30.65	5.00e-92	332.00
IUUC-Pva-102142	Pteropus vampyrus	67.91	0.00e+00	1600.00
IUUC-Pgr-103446	Puccinia graminis	30.79	1.00e-65	244.00
IUUC-Ptt-103849	Puccinia triticina	29.83	1.00e-68	255.00
IUUC-Pte-104128	Pyrenophora teres	30.56	6.00e-89	322.00
IUUC-Pyt-104754	Pyrenophora triticirepentis	29.38	2.00e-100	360.00
IUUC-Rno-104871	Rattus norvegicus	65.51	0.00e+00	1546.00
IUUC-Sce-106236	Saccharomyces cerevisiae	31.09	1.00e-37	152.00
IUUC-Sha-106962	Sarcophilus harrisii	70.43	0.00e+00	1643.00
IUUC-Sja-107691	Schizosaccharomyces japonicus	31.91	9.00e-62	231.00
IUUC-Spo-108170	Schizosaccharomyces pombe	33.81	1.00e-66	248.00
IUUC-Ssl-108668	Sclerotinia sclerotiorum	27.23	1.00e-104	374.00
IUUC-Smo-109554	Selaginella moellendorffii	37.06	3.00e-85	310.00
IUUC-Sit-110479	Setaria italica	31.31	2.00e-77	283.00
IUUC-Sly-111752	Solanum lycopersicum	28.41	4.00e-99	356.00
IUUC-Sar-113304	Sorex araneus	68.25	0.00e+00	1563.00
IUUC-Sbi-114196	Sorghum bicolor	38.18	1.00e-77	284.00
IUUC-Sre-115151	Sporisorium reilianum	31.25	2.00e-82	300.00
IUUC-Ssc-116104	Sus scrofa	68.23	0.00e+00	1610.00
IUUC-Tgu-117438	Taeniopygia guttata	70.62	0.00e+00	1640.00
IUUC-Tru-118553	Takifugu rubripes	52.18	0.00e+00	854.00
IUUC-Tsy-119056	Tarsius syrichta	65.85	0.00e+00	1471.00
IUUC-Tni-119933	Tetraodon nigroviridis	48.65	0.00e+00	807.00
IUUC-Tca-121376	Theobroma cacao	30.70	6.00e-109	389.00
IUUC-Tre-121972	Trichoderma reesei	27.33	4.00e-82	299.00
IUUC-Tvi-122342	Trichoderma virens	29.21	2.00e-80	293.00
IUUC-Tae-123898	Triticum aestivum	31.07	3.00e-109	389.00
IUUC-Tur-126735	Triticum urartu	37.23	4.00e-35	143.00
IUUC-Tme-126999	Tuber melanosporum	32.80	2.00e-80	294.00
IUUC-Tbe-127280	Tupaia belangeri	67.83	6.00e-101	362.00
IUUC-Ttr-129104	Tursiops truncatus	68.17	0.00e+00	1590.00
IUUC-Uma-129562	Ustilago maydis	30.05	1.00e-84	308.00
IUUC-Vda-129862	Verticillium dahliae	30.58	5.00e-92	332.00
IUUC-Vpa-130819	Vicugna pacos	66.92	0.00e+00	850.00
IUUC-Vvi-131111	Vitis vinifera	35.06	5.00e-85	309.00
IUUC-Xtr-132629	Xenopus tropicalis	59.84	0.00e+00	1362.00
IUUC-Xma-134065	Xiphophorus maculatus	49.73	0.00e+00	807.00
IUUC-Yli-134633	Yarrowia lipolytica	31.51	9.00e-62	232.00
IUUC-Zma-135176	Zea mays	34.56	2.00e-89	323.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence