iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aml-002332

Ensembl Protein ID

ENSAMEP00000014853.1

UniProt Accession

G1M683; G1M683_AILME

Genbank Protein ID

ENSAMEP00000014853

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ACTA01068126

Gene Name

BRWD1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000014080.1	ENSAMET00000015466.1	ENSAMEP00000014853.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.80e-35	118.9	118	155
UBD/Beta-Prp	4.30e-55	187.1	220	477

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           gH + v+c+af  + +++ +GsdD+ +k+W+++ g+ll
   Q: 118  GHLSAVYCVAFdRTgHRIFTGSDDCLVKIWSTHNGRLL 155
           8**********955599***************999987 PP

UBD/Beta-Prp

   S: 22   ksllatgsrdgtikvwdvttgkl......lrslsgheaevtavk..fspdgkilvtgseDrtikvw..dlstgkcvhtlkghedsvlsl 100
           +++++++++dgt+  w+++ ++l      l+  ++  ++v+ ++  fs  g +l+tgs+D++i+ +   +++++ +  l+ h+d+v s+
   Q: 220  QRYMVSTGADGTVCFWQWDLESLkfsprpLKFTEKPRPGVQMLCssFSVGGMFLATGSTDHVIRMYflGFEAPEKIAELESHTDKVDSI 308
           689*****************99999988777778888888755522888888**************99999****************** PP
   S: 101  sfspsgdklvsGshdrtirvwdletgqclee...............tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrt 174
           +f+ +gd+++sGs+d t+r+w  e+ ++ +                 ++  +  v++++++++++++v++ +D ++++W++ tg+ll+ 
   Q: 309  QFCNNGDRFLSGSRDGTARIWRFEQLEWRSIlldmatrvsgdlsleEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHN 397
           **************************99998999*********98877778889*********************************** PP
   S: 175  ltgghtdsvysls...fdsngkelvsgsldgtvklwdlqtgecvrtlnght.....dnvksvrfspnderlvsgssDgsiriW 249
           l g h d v  l+   fds  + ++s+++dg++ +wd+ +g+ ++ + +         v + +fs+++++++++ s+g + i+
   Q: 398  LLG-HADEVFVLEthpFDS--RIMLSAGHDGSIFIWDITKGTKMKHYFNMIegqghGAVFDCKFSQDGQHFACTDSHGHLLIF 477
           **9.*********555555..99****************999977766544444456677789999*****999999998886 PP

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

VLSNKHVAPD HLLQICQRIG PMLDKEIPPS ISRVTSLLGA GRQSLLRTAK DCRHTVWKGS 60
AFAALHRGRP PEMPVNYGSP PSLVEIHRGK QLTGCSTFST AFPGAMYQHI KMHRRILGHL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTCTTGTCCA ATAAGCATGT GGCTCCTGAT CATCTGTTGC AAATCTGCCA ACGCATTGGT 60
CCCATGTTGG ATAAAGAGAT TCCACCCAGT ATTTCAAGAG TCACTTCTTT ACTTGGTGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0103--Bromodomain
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00439--Bromodomain
PF00400--WD40

PRINTS

PR00503--BROMODOMAIN

SMART

SM00297--BROMO
SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005730--C:nucleolus
GO:0007010--P:cytoskeleton organization
GO:0008360--P:regulation of cell shape
GO:0006357--P:regulation of transcription from RNA polymerase II promoter

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-004083	Anas platyrhynchos	61.80	0.00e+00	2066.00
IUUC-Bta-013217	Bos taurus	85.79	0.00e+00	3418.00
IUUC-Cja-019966	Callithrix jacchus	83.78	0.00e+00	3349.00
IUUC-Cfa-021037	Canis familiaris	90.62	0.00e+00	3542.00
IUUC-Cpo-021934	Cavia porcellus	91.75	0.00e+00	2648.00
IUUC-Csa-023352	Chlorocebus sabaeus	84.05	0.00e+00	3189.00
IUUC-Cho-024690	Choloepus hoffmanni	71.87	0.00e+00	1124.00
IUUC-Dno-028938	Dasypus novemcinctus	83.39	0.00e+00	3364.00
IUUC-Ete-032717	Echinops telfairi	79.17	0.00e+00	800.00
IUUC-Eca-034349	Equus caballus	87.37	0.00e+00	3362.00
IUUC-Fca-035485	Felis catus	93.15	0.00e+00	3153.00
IUUC-Fal-037307	Ficedula albicollis	71.67	0.00e+00	2350.00
IUUC-Ggo-045500	Gorilla gorilla	84.82	0.00e+00	3353.00
IUUC-Hsa-046350	Homo sapiens	84.82	0.00e+00	3356.00
IUUC-Itr-047962	Ictidomys tridecemlineatus	94.78	0.00e+00	1129.00
IUUC-Lch-049662	Latimeria chalumnae	65.19	0.00e+00	2016.00
IUUC-Laf-053848	Loxodonta africana	84.32	0.00e+00	3284.00
IUUC-Mcc-054638	Macaca mulatta	84.87	0.00e+00	3355.00
IUUC-Meu-056739	Macropus eugenii	79.91	0.00e+00	1118.00
IUUC-Mga-060165	Meleagris gallopavo	77.38	0.00e+00	2217.00
IUUC-Mmr-061227	Microcebus murinus	85.34	0.00e+00	3359.00
IUUC-Mdo-062074	Monodelphis domestica	71.31	0.00e+00	2665.00
IUUC-Mmu-064075	Mus musculus	81.63	0.00e+00	2839.00
IUUC-Mpu-066643	Mustela putorius furo	96.92	0.00e+00	3171.00
IUUC-Mlu-067735	Myotis lucifugus	84.74	0.00e+00	3360.00
IUUC-Nle-069402	Nomascus leucogenys	92.40	0.00e+00	2925.00
IUUC-Oan-072954	Ornithorhynchus anatinus	76.91	0.00e+00	2610.00
IUUC-Ocu-074456	Oryctolagus cuniculus	82.69	0.00e+00	3392.00
IUUC-Ogl-077493	Oryza glaberrima	27.29	1.00e-29	125.00
IUUC-Olu-087745	Ostreococcus lucimarinus	27.87	4.00e-55	210.00
IUUC-Oga-087938	Otolemur garnettii	78.82	0.00e+00	2889.00
IUUC-Oar-090214	Ovis aries	85.35	0.00e+00	3383.00
IUUC-Ptr-091213	Pan troglodytes	84.91	0.00e+00	3318.00
IUUC-Pan-092444	Papio anubis	84.38	0.00e+00	3336.00
IUUC-Pfo-097318	Poecilia formosa	62.14	0.00e+00	1702.00
IUUC-Pab-097573	Pongo abelii	84.08	0.00e+00	3253.00
IUUC-Pca-100759	Procavia capensis	72.75	0.00e+00	1100.00
IUUC-Pva-102782	Pteropus vampyrus	85.81	0.00e+00	3442.00
IUUC-Rno-105687	Rattus norvegicus	75.61	0.00e+00	3012.00
IUUC-Sar-113519	Sorex araneus	82.12	0.00e+00	1793.00
IUUC-Tgu-116513	Taeniopygia guttata	77.37	0.00e+00	2239.00
IUUC-Tsy-118921	Tarsius syrichta	89.25	0.00e+00	1950.00
IUUC-Tbe-127663	Tupaia belangeri	86.84	0.00e+00	1225.00
IUUC-Ttr-128561	Tursiops truncatus	83.58	0.00e+00	3187.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence