iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000009615.1	ENSOART00000010488.1	ENSOARP00000010334.1
ENSOARG00000009615.1	ENSOART00000010492.1	ENSOARP00000010338.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.20e-35	118.8	97	134
UBD/Beta-Prp	4.30e-55	187.2	199	456

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           gH + v+c+af  + +++ +GsdD+ +k+W+++ g+ll
   Q: 97   GHLSAVYCVAFdRTgHRIFTGSDDCLVKIWSTHNGRLL 134
           8**********955599***************999987 PP

UBD/Beta-Prp

   S: 22   ksllatgsrdgtikvwdvttgkl......lrslsgheaevtavk..fspdgkilvtgseDrtikvw..dlstgkcvhtlkghedsvlsl 100
           +++++++++dgt+  w+++ ++l      l+  ++  ++v+ ++  fs  g +l+tgs+D++i+ +   +++++ +  l+ h+d+v s+
   Q: 199  QRYMVSTGADGTVCFWQWDLESLkfsprpLKFTEKPRPGVQMLCssFSVGGMFLATGSTDHVIRMYflGFEAPEKIAELESHTDKVDSI 287
           689*****************99999988777778888888755522888888**************99999****************** PP
   S: 101  sfspsgdklvsGshdrtirvwdletgqclee...............tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrt 174
           +f+ +gd+++sGs+d t+r+w  e+ ++ +                 ++  +  v++++++++++++v++ +D ++++W++ tg+ll+ 
   Q: 288  QFCNNGDRFLSGSRDGTARIWRFEQLEWRSIlldmatrisgdlsleEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHN 376
           **************************99998999*********98877778889*********************************** PP
   S: 175  ltgghtdsvysls...fdsngkelvsgsldgtvklwdlqtgecvrtlnght.....dnvksvrfspnderlvsgssDgsiriW 249
           l g h d v  l+   fds  + ++s+++dg++ +wd+ +g+ ++ + +         v + +fs+++++++++ s+g + i+
   Q: 377  LLG-HADEVFVLEthpFDS--RIMLSAGHDGSIFIWDITKGTKMKHYFNMIegqghGAVFDCKFSQDGQHFACTDSHGHLLIF 456
           **9.*********555555..99****************999977766544444456677789999*****999999998886 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MLDKEIPPSI SRVTSLLGAG RQSLLRTAKD CRHTVWKGSA FAALHRGRPP EMPVNYGSPP 60
NLVEIHRGKQ LTGCSTFSTA FPGAMYQHIK MHRRILGHLS AVYCVAFDRT GHRIFTGSDD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTCTTGTCCA ATAAGCATGT GGCTCCTGAC CATCTGTTGC AAATCTGCCA ACGCATCGGT 60
CCCATGCTGG ATAAAGAGAT CCCACCCAGC ATTTCAAGAG TCACTTCTTT ACTTGGGGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0103--Bromodomain
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00439--Bromodomain
PF00400--WD40

PRINTS

PR00503--BROMODOMAIN

SMART

SM00297--BROMO
SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005730--C:nucleolus
GO:0007010--P:cytoskeleton organization
GO:0008360--P:regulation of cell shape
GO:0006357--P:regulation of transcription from RNA polymerase II promoter

KEGG

oas:101117901

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002332	Ailuropoda melanoleuca	85.76	0.00e+00	3289.00
IUUC-Apl-004083	Anas platyrhynchos	57.62	0.00e+00	2046.00
IUUC-Ath-006801	Arabidopsis thaliana	31.66	1.00e-64	242.00
IUUC-Bta-013217	Bos taurus	98.03	0.00e+00	3955.00
IUUC-Bol-015737	Brassica oleracea	31.36	2.00e-68	255.00
IUUC-Bra-017961	Brassica rapa	31.49	4.00e-68	254.00
IUUC-Cja-019966	Callithrix jacchus	86.64	0.00e+00	3474.00
IUUC-Cfa-021037	Canis familiaris	88.52	0.00e+00	3538.00
IUUC-Cpo-021934	Cavia porcellus	91.25	0.00e+00	2593.00
IUUC-Csa-023352	Chlorocebus sabaeus	86.72	0.00e+00	3391.00
IUUC-Cho-024690	Choloepus hoffmanni	78.04	0.00e+00	1333.00
IUUC-Dno-028938	Dasypus novemcinctus	85.62	0.00e+00	3464.00
IUUC-Ete-032717	Echinops telfairi	80.08	0.00e+00	811.00
IUUC-Eca-034349	Equus caballus	89.39	0.00e+00	3535.00
IUUC-Fca-035485	Felis catus	89.18	0.00e+00	3059.00
IUUC-Ggo-045500	Gorilla gorilla	86.80	0.00e+00	3499.00
IUUC-Hsa-046350	Homo sapiens	86.94	0.00e+00	3519.00
IUUC-Itr-047962	Ictidomys tridecemlineatus	95.42	0.00e+00	1128.00
IUUC-Lch-049662	Latimeria chalumnae	66.25	0.00e+00	1958.00
IUUC-Laf-053848	Loxodonta africana	86.56	0.00e+00	3423.00
IUUC-Mcc-054638	Macaca mulatta	87.43	0.00e+00	3495.00
IUUC-Meu-056739	Macropus eugenii	78.98	0.00e+00	1064.00
IUUC-Mga-060165	Meleagris gallopavo	77.43	0.00e+00	2164.00
IUUC-Mmr-061227	Microcebus murinus	87.60	0.00e+00	3488.00
IUUC-Mdo-062074	Monodelphis domestica	69.91	0.00e+00	2672.00
IUUC-Mmu-064075	Mus musculus	80.91	0.00e+00	2791.00
IUUC-Mpu-066643	Mustela putorius furo	91.92	0.00e+00	3026.00
IUUC-Mlu-067735	Myotis lucifugus	86.68	0.00e+00	3467.00
IUUC-Nle-069402	Nomascus leucogenys	90.76	0.00e+00	2845.00
IUUC-Oan-072954	Ornithorhynchus anatinus	70.61	0.00e+00	2686.00
IUUC-Ocu-074456	Oryctolagus cuniculus	85.12	0.00e+00	3475.00
IUUC-Ogl-077493	Oryza glaberrima	27.34	2.00e-29	125.00
IUUC-Olu-087745	Ostreococcus lucimarinus	28.06	3.00e-55	211.00
IUUC-Oga-087938	Otolemur garnettii	80.40	0.00e+00	2986.00
IUUC-Ptr-091213	Pan troglodytes	87.34	0.00e+00	3471.00
IUUC-Pan-092444	Papio anubis	86.14	0.00e+00	3475.00
IUUC-Pab-097573	Pongo abelii	86.09	0.00e+00	3399.00
IUUC-Pca-100759	Procavia capensis	71.45	0.00e+00	1050.00
IUUC-Pva-102782	Pteropus vampyrus	88.56	0.00e+00	3574.00
IUUC-Rno-105687	Rattus norvegicus	76.85	0.00e+00	3076.00
IUUC-Sar-113519	Sorex araneus	82.00	0.00e+00	1789.00
IUUC-Tsy-118921	Tarsius syrichta	88.74	0.00e+00	1890.00
IUUC-Tbe-127663	Tupaia belangeri	75.97	0.00e+00	1295.00
IUUC-Ttr-128561	Tursiops truncatus	88.57	0.00e+00	3448.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence