iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ssc-115643

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

CU468330

Gene Name

WSB2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000009853.2	ENSSSCT00000010800.2	ENSSSCP00000010517.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	8.20e-15	54.7	356	403
E3 adaptor/Cullin RING/DCX/DWD	1.90e-32	110.1	151	184
UBD/Beta-Prp	4.80e-46	157.5	125	360

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 1    lsklwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyed 51
           ++++w++++   SL+hLCR+a r++l+++++    +LP+Pk++k++L y++
   Q: 356  HVQFWTAPRVLSSLKHLCRKALRSFLTTYQV---LALPIPKKMKEFLTYRT 403
           689****************************...***************86 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sd.tllvsGsdDgtikvWDlr 31
           gH+d v++l+f  s+  +lvs+s+D+t+++WDl 
   Q: 151  GHQDVVRDLSFtpSGsLILVSASRDKTLRIWDLN 184
           8***********6556779*************85 PP

UBD/Beta-Prp

   S: 24   llatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgk.ilvtgseDrtikvwdls.tgkcvhtlkghedsvlslsfspsgdklv 110
           +latg  dg ik+w+v+tg ll  lsgh++ v++++f p+g+ ilv++s+D+t+++wdl+  gk++++l+gh + v+++s+sp+ + l 
   Q: 125  ILATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSlILVSASRDKTLRIWDLNkHGKQIQVLSGHLQWVYCCSISPDCSMLC 213
           79****************************************9****************9789********************99**** PP
   S: 111  sGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl...........tgghtdsvyslsf 188
           s+   + + +w +++++ ++  l+gh+++v +  ++pd+ llv++s+D+ v +Wd  tg+ lr l           +  h +s +s+ f
   Q: 214  SAAGEKSVFLWSMRSYTLIR-KLEGHQSSVVSCDFSPDSALLVTASYDTNVIMWDPYTGERLRSLhhtqlsppmddSDVHISSLRSVCF 301
           ********************.********************************************9999***9999778999999999* PP
   S: 189  dsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriW 249
           +++g +l+++++d+ +++w l+ ++   +  +  +n ++  f+p++  +++g+ Dg +++W
   Q: 302  SPEGLYLATVADDRLLRIWALELKT--PIAFAPMTNGLCCTFFPHGGVIATGTRDGHVQFW 360
           *********************9885..7899****************************** PP

Organism

Sus scrofa

Protein Sequence
(Fasta)

MEAGEEPLLL AELKPGRPHQ FDWKSSCETW SVAFSPDGSW FAWSQGHCIV KLIPWPLEEQ 60
FIPKGFEAKS RSSKNDTKGR GSPKEKTLDC GQIVWGLAFS PWPSPPSRKL WARHHPQVPD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCCTTCA TGGAGGCCGG AGGTGAGTGG GGGCCGTGGC GCGCGTTCCC CGCCGACGGA 60
GCCGGGCCCG TTCCCGGGGG GTGGGGCGCG GGCGCGGATT CGGTCGGGGC GGGGGCGGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR003143--Cyt_cd1_C
IPR020472--G-protein_beta_WD-40_rep
IPR001496--SOCS_box
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50225--SOCS
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF07525--SOCS_box
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00253--SOCS
SM00969--SOCS_box
SM00320--WD40

Gene Ontology

GO:0005622--C:intracellular
GO:0035556--P:intracellular signal transduction
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002221	Ailuropoda melanoleuca	99.00	0.00e+00	816.00
IUUC-Apl-004107	Anas platyrhynchos	68.77	1.00e-131	462.00
IUUC-Aca-004354	Anolis carolinensis	73.38	2.00e-168	584.00
IUUC-Bta-012627	Bos taurus	99.23	0.00e+00	781.00
IUUC-Cja-018897	Callithrix jacchus	97.17	0.00e+00	780.00
IUUC-Cfa-020122	Canis familiaris	99.25	0.00e+00	816.00
IUUC-Cpo-022540	Cavia porcellus	97.95	0.00e+00	790.00
IUUC-Csa-023719	Chlorocebus sabaeus	98.45	0.00e+00	790.00
IUUC-Cho-024367	Choloepus hoffmanni	97.99	9.00e-173	598.00
IUUC-Dno-029021	Dasypus novemcinctus	98.98	0.00e+00	797.00
IUUC-Dor-030321	Dipodomys ordii	97.94	0.00e+00	785.00
IUUC-Ete-032955	Echinops telfairi	97.99	0.00e+00	783.00
IUUC-Eca-033485	Equus caballus	99.23	0.00e+00	770.00
IUUC-Fca-035389	Felis catus	98.97	0.00e+00	795.00
IUUC-Fal-037184	Ficedula albicollis	84.45	6.00e-143	499.00
IUUC-Gga-041014	Gallus gallus	77.08	4.00e-176	610.00
IUUC-Ggo-045585	Gorilla gorilla	98.72	0.00e+00	798.00
IUUC-Hsa-046344	Homo sapiens	98.72	0.00e+00	798.00
IUUC-Itr-049085	Ictidomys tridecemlineatus	98.46	0.00e+00	793.00
IUUC-Lch-050131	Latimeria chalumnae	70.27	3.00e-168	583.00
IUUC-Loc-052807	Lepisosteus oculatus	54.48	1.00e-116	412.00
IUUC-Laf-053528	Loxodonta africana	98.47	0.00e+00	774.00
IUUC-Mcc-055665	Macaca mulatta	98.72	0.00e+00	798.00
IUUC-Meu-056054	Macropus eugenii	88.35	0.00e+00	700.00
IUUC-Mga-059326	Meleagris gallopavo	77.19	0.00e+00	628.00
IUUC-Mmr-060815	Microcebus murinus	96.42	0.00e+00	781.00
IUUC-Mdo-062000	Monodelphis domestica	91.32	0.00e+00	754.00
IUUC-Mmu-063927	Mus musculus	96.92	0.00e+00	781.00
IUUC-Mpu-065726	Mustela putorius furo	97.43	0.00e+00	781.00
IUUC-Mlu-067527	Myotis lucifugus	98.10	3.00e-120	423.00
IUUC-Nle-069680	Nomascus leucogenys	98.21	0.00e+00	789.00
IUUC-Opr-070356	Ochotona princeps	97.99	0.00e+00	800.00
IUUC-Oan-073647	Ornithorhynchus anatinus	83.94	6.00e-136	476.00
IUUC-Ocu-073973	Oryctolagus cuniculus	97.44	0.00e+00	782.00
IUUC-Oga-088797	Otolemur garnettii	98.21	0.00e+00	788.00
IUUC-Oar-089187	Ovis aries	99.23	0.00e+00	781.00
IUUC-Ptr-091317	Pan troglodytes	98.72	0.00e+00	796.00
IUUC-Pan-092694	Papio anubis	90.65	0.00e+00	679.00
IUUC-Psi-093392	Pelodiscus sinensis	79.90	0.00e+00	644.00
IUUC-Pab-098145	Pongo abelii	98.45	0.00e+00	789.00
IUUC-Pca-100454	Procavia capensis	89.47	0.00e+00	724.00
IUUC-Pva-102986	Pteropus vampyrus	90.23	0.00e+00	727.00
IUUC-Rno-104931	Rattus norvegicus	95.88	0.00e+00	772.00
IUUC-Sha-106476	Sarcophilus harrisii	92.25	0.00e+00	748.00
IUUC-Tgu-117522	Taeniopygia guttata	63.95	5.00e-136	476.00
IUUC-Tsy-119301	Tarsius syrichta	98.75	0.00e+00	812.00
IUUC-Ttr-128683	Tursiops truncatus	99.74	0.00e+00	796.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence