iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ggo-045531

UUCD1 version

UUC-GoG-00111

Ensembl Protein ID

ENSGGOP00000002667.2

UniProt Accession

G3QJR4; G3QJR4_GORGO

Protein Name

Uncharacterized protein

Gene Name

ZNRF4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000002709.2	ENSGGOT00000002721.2	ENSGGOP00000002667.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	5.10e-10	40.1	310	353

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdg..plvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           CaiCl+++++g  +++lpC H++h++C+  w     s+ ++ +CP+C+
   Q: 310  CAICLDEYEEGdqLKILPCSHTYHRKCIDPW----FSQAPRRSCPVCK 353
           ********55555******************....9***********7 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

VLLCRPEYLM PRASRVPVAA SLPLSHAVIP TQLPSHPGHR PPGRPRRCPK ASCLPPPVGP 60
SSTQPAKRVT MGWPRPGRAL VAVKALLVLL LLQVPAQAVV RAMLEDNSSS VDFADLPALF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATCTGCCAGA AAGGCTACCT GCGCCAGCAC CTCCTGAGAC CGGCCTTCAA AGACACGATG 60
CGTGCTGCTC TGCCGTCCGG AGTACTTAAT GCCTAGAGCC AGCAGGGTCC CAGTGGCCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR003137--PA_domain
IPR001841--Znf_RING
IPR011016--Znf_RING-CH
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF02225--PA
PF13639--zf-RING_2

SMART

SM00184--RING
SM00744--RINGv

Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0016021--C:integral component of membrane
GO:0008270--F:zinc ion binding
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001654	Ailuropoda melanoleuca	71.98	7.00e-132	463.00
IUUC-Bta-012572	Bos taurus	67.89	1.00e-112	399.00
IUUC-Cja-019445	Callithrix jacchus	78.97	2.00e-151	528.00
IUUC-Cfa-020828	Canis familiaris	72.70	3.00e-122	431.00
IUUC-Csa-023281	Chlorocebus sabaeus	91.40	3.00e-178	617.00
IUUC-Dor-030690	Dipodomys ordii	54.39	2.00e-58	218.00
IUUC-Ete-032610	Echinops telfairi	66.23	3.00e-120	425.00
IUUC-Hsa-045802	Homo sapiens	95.09	0.00e+00	697.00
IUUC-Itr-048891	Ictidomys tridecemlineatus	74.92	3.00e-111	394.00
IUUC-Laf-053469	Loxodonta africana	69.52	1.00e-114	405.00
IUUC-Mcc-054662	Macaca mulatta	91.63	8.00e-179	619.00
IUUC-Meu-056499	Macropus eugenii	58.16	3.00e-94	338.00
IUUC-Mdo-062468	Monodelphis domestica	53.58	1.00e-99	356.00
IUUC-Mmu-064409	Mus musculus	50.98	5.00e-59	221.00
IUUC-Mpu-066553	Mustela putorius furo	72.28	1.00e-129	456.00
IUUC-Oan-073710	Ornithorhynchus anatinus	50.00	5.00e-67	247.00
IUUC-Ptr-090842	Pan troglodytes	96.98	0.00e+00	695.00
IUUC-Pan-092278	Papio anubis	91.86	1.00e-180	625.00
IUUC-Pab-097537	Pongo abelii	92.33	2.00e-175	608.00
IUUC-Rno-104830	Rattus norvegicus	48.45	2.00e-54	205.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence