iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000014679.1	ENSLACT00000016778.1	ENSLACP00000016664.1
ENSLACG00000014679.1	ENSLACT00000016779.1	ENSLACP00000016665.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	5.90e-62	210.0	105	478
ULD/UDP/UBQ/UBQ_Other	1.10e-07	31.8	6	74

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefs.... 85
           +Gl+NlgNtCYmN+++QcL ++pel+ +l++ ++ +l+++    p ++++ +l++l   + +++ +++ p  ll+ l+ + ++f     
   Q: 105  CGLTNLGNTCYMNATVQCLRSVPELKVALKK-YPGALRASGAMVPAQCITAALRDLYDGM-EKTASSIPPIILLQFLHIAFPQFAekse 191
           7*****************************9.****************************.99999******************99999 PP
   S: 86   ..gyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldl 172
             +y qqDa+E++ +++  l+++l++ ++ p +e+          +++  + + +k++i++ F++++++++kc e + +  ++ + ++l
   Q: 192  qgQYLQQDANECWLQMMRVLQQKLDQAEQDPPMET----------DSDAATASTKKNFIDQFFGIEFETTMKCSEAEDEEAKKGKETQL 270
           999*********************66555555555..........56679999***********************9999887777777 PP
   S: 173  slpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdl 261
           +l+   ++e   + l   L+   +ee  +     ++++ +++    k+ k+++lP +L++++ Rf ++e+++++ k+ k v+fpl+Ld+
   Q: 271  QLSCFINQEV--KYLFTGLRLRLQEEITK-----HSPTLQRNALYIKSSKISRLPAYLTVQMVRFFYKEKESVNAKVLKDVKFPLMLDV 352
           7777766643..47999999988888887.....8999999999********************************************* PP
   S: 262  spfcts........................peekqke............................kkkYeLiavvvHsG.slssGHYva 297
            + ct+                        +     +                            +  Y+L av+ H+G s+ssGHYv 
   Q: 353  FELCTTelqekmtpyrskfkemedkvlqqqK-----KtssqevnggqkevkyepfsfpddvgsnnSGYYDLQAVLTHQGrSSSSGHYVG 436
           *****96666666666666666666665550.....0445556666666777777777777777799********************** PP
   S: 298  yvknekgkWllfdDskVtevkeeevleetg....staYvlfY 335
           +vk + ++W++fdD+kV++v+ e++l+ +g    + aYvl+Y
   Q: 437  WVKRKADEWIKFDDDKVSVVTPEDILRLSGggdwHIAYVLLY 478
           ***************************988************ PP

ULD/UDP/UBQ/UBQ_Other

   S: 3    vtvksldgseltlkvnpsdtVaeLKekiekklgippeqqrLiykGkiLeddktLadyglkdgstihllek 72
           v vk+ + +  ++++n +++  ++K +++ ++g++pe+q+ ++kG  L+d   +++ +lk+g+t++++ +
   Q: 6    VNVKWGKEKFDGVELNTDEPPVVFKAQLFALTGVQPERQKVMVKGGTLKDE-EWGNIKLKNGMTLLMMGS 74
           67999999988999**********************************999.***************976 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

VLVFAVNVKW GKEKFDGVEL NTDEPPVVFK AQLFALTGVQ PERQKVMVKG GTLKDEEWGN 60
IKLKNGMTLL MMGSAEALPE EPVVRPLFVE DMTEEQLASA MELPCGLTNL GNTCYMNATV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAACTGCAGT GCACACACAC ATATTACTGC CATCTAATGG CCAATTGTGT ACTTAACAAG 60
TTAGGGAGAA ATGAGAACTG AACCAGGGAA CTTAATATTA CTGTCTTCTG GTTTCAATTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR029071--Ubiquitin-rel_dom
IPR019954--Ubiquitin_CS
IPR000626--Ubiquitin_dom
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00299--UBIQUITIN_1
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

SMART

SM00213--UBQ

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000893	Aegilops tauschii	32.43	2.00e-37	150.00
IUUC-Aml-002053	Ailuropoda melanoleuca	82.72	0.00e+00	801.00
IUUC-Atr-002725	Amborella trichopoda	41.22	6.00e-97	347.00
IUUC-Apl-004031	Anas platyrhynchos	84.29	0.00e+00	831.00
IUUC-Aca-004361	Anolis carolinensis	83.50	0.00e+00	848.00
IUUC-Aly-006078	Arabidopsis lyrata	41.96	1.00e-108	386.00
IUUC-Ath-007623	Arabidopsis thaliana	41.55	1.00e-108	386.00
IUUC-Ago-007796	Ashbya gossypii	32.02	5.00e-56	211.00
IUUC-Acl-008258	Aspergillus clavatus	38.68	1.00e-64	241.00
IUUC-Afl-008732	Aspergillus flavus	34.53	6.00e-77	281.00
IUUC-Afu-008755	Aspergillus fumigatus	34.09	2.00e-75	276.00
IUUC-Ani-009148	Aspergillus nidulans	36.08	1.00e-86	313.00
IUUC-Ang-009878	Aspergillus niger	34.33	9.00e-76	277.00
IUUC-Aor-010239	Aspergillus oryzae	34.53	7.00e-77	281.00
IUUC-Ate-010243	Aspergillus terreus	35.86	2.00e-77	282.00
IUUC-Ame-011327	Astyanax mexicanus	52.85	8.00e-128	450.00
IUUC-Bgr-012231	Blumeria graminis	35.61	3.00e-80	292.00
IUUC-Bta-012553	Bos taurus	82.24	0.00e+00	810.00
IUUC-Bci-013606	Botrytis cinerea	42.26	4.00e-71	262.00
IUUC-Bdi-014567	Brachypodium distachyon	43.12	2.00e-110	392.00
IUUC-Bol-015565	Brassica oleracea	41.58	7.00e-111	394.00
IUUC-Bra-017501	Brassica rapa	41.38	4.00e-108	384.00
IUUC-Cel-018140	Caenorhabditis elegans	41.60	4.00e-101	361.00
IUUC-Cja-019516	Callithrix jacchus	81.74	0.00e+00	814.00
IUUC-Cfa-020808	Canis familiaris	82.65	0.00e+00	813.00
IUUC-Cpo-021688	Cavia porcellus	81.95	0.00e+00	806.00
IUUC-Cre-022663	Chlamydomonas reinhardtii	37.17	1.00e-82	300.00
IUUC-Csa-023429	Chlorocebus sabaeus	82.45	0.00e+00	796.00
IUUC-Cho-024347	Choloepus hoffmanni	82.04	0.00e+00	808.00
IUUC-Cin-025198	Ciona intestinalis	53.99	4.00e-151	527.00
IUUC-Csv-026007	Ciona savignyi	53.75	1.00e-152	532.00
IUUC-Cgl-026757	Colletotrichum gloeosporioides	42.12	1.00e-66	247.00
IUUC-Cne-026963	Cryptococcus neoformans	35.47	5.00e-75	275.00
IUUC-Cme-027240	Cyanidioschyzon merolae	30.95	2.00e-63	236.00
IUUC-Dre-027647	Danio rerio	83.57	0.00e+00	846.00
IUUC-Dno-029967	Dasypus novemcinctus	82.04	0.00e+00	794.00
IUUC-Dor-030886	Dipodomys ordii	76.03	0.00e+00	641.00
IUUC-Dse-031466	Dothistroma septosporum	36.83	1.00e-57	217.00
IUUC-Dme-032079	Drosophila melanogaster	55.81	9.00e-158	549.00
IUUC-Ete-032351	Echinops telfairi	74.54	0.00e+00	742.00
IUUC-Eca-033461	Equus caballus	81.91	0.00e+00	848.00
IUUC-Eeu-035220	Erinaceus europaeus	64.05	1.00e-169	589.00
IUUC-Fca-036210	Felis catus	82.86	0.00e+00	815.00
IUUC-Fal-037528	Ficedula albicollis	83.74	0.00e+00	806.00
IUUC-Fox-037805	Fusarium oxysporum	40.79	1.00e-72	267.00
IUUC-Fso-038177	Fusarium solani	36.20	2.00e-84	306.00
IUUC-Gmo-038953	Gadus morhua	80.16	0.00e+00	780.00
IUUC-Ggr-039972	Gaeumannomyces graminis	40.69	4.00e-66	245.00
IUUC-Gga-040462	Gallus gallus	83.40	0.00e+00	817.00
IUUC-Gac-041312	Gasterosteus aculeatus	82.72	0.00e+00	815.00
IUUC-Gma-043255	Glycine max	41.73	3.00e-105	375.00
IUUC-Ggo-045458	Gorilla gorilla	69.15	0.00e+00	672.00
IUUC-Hsa-045706	Homo sapiens	82.45	0.00e+00	796.00
IUUC-Hvu-047821	Hordeum vulgare	45.70	5.00e-56	210.00
IUUC-Itr-048654	Ictidomys tridecemlineatus	80.61	0.00e+00	814.00
IUUC-Lpe-051419	Leersia perrieri	41.67	4.00e-106	377.00
IUUC-Loc-052732	Lepisosteus oculatus	83.50	0.00e+00	844.00
IUUC-Lma-053177	Leptosphaeria maculans	40.16	4.00e-69	255.00
IUUC-Laf-053822	Loxodonta africana	82.52	0.00e+00	814.00
IUUC-Mcc-055893	Macaca mulatta	82.45	0.00e+00	796.00
IUUC-Meu-056307	Macropus eugenii	73.77	0.00e+00	716.00
IUUC-Mor-057171	Magnaporthe oryzae	42.18	7.00e-71	261.00
IUUC-Mpo-057415	Magnaporthe poae	41.73	2.00e-70	259.00
IUUC-Mtr-057901	Medicago truncatula	42.42	5.00e-108	384.00
IUUC-Mla-058897	Melampsora laricipopulina	40.53	1.00e-77	283.00
IUUC-Mga-060016	Meleagris gallopavo	83.88	0.00e+00	827.00
IUUC-Mvi-060562	Microbotryum violaceum	40.11	2.00e-68	253.00
IUUC-Mmr-060624	Microcebus murinus	82.04	0.00e+00	843.00
IUUC-Mdo-061809	Monodelphis domestica	83.13	0.00e+00	810.00
IUUC-Mmu-063869	Mus musculus	81.22	0.00e+00	801.00
IUUC-Mac-064876	Musa acuminata	39.88	5.00e-94	338.00
IUUC-Mpu-066480	Mustela putorius furo	82.24	0.00e+00	810.00
IUUC-Mlu-067866	Myotis lucifugus	81.91	0.00e+00	823.00
IUUC-Nfi-068393	Neosartorya fischeri	33.57	2.00e-72	266.00
IUUC-Ncr-068815	Neurospora crassa	35.92	1.00e-75	277.00
IUUC-Nle-070121	Nomascus leucogenys	80.88	8.00e-117	412.00
IUUC-Opr-070712	Ochotona princeps	65.96	3.00e-148	518.00
IUUC-Ont-071544	Oreochromis niloticus	83.27	0.00e+00	772.00
IUUC-Oan-073635	Ornithorhynchus anatinus	81.41	0.00e+00	665.00
IUUC-Ocu-074926	Oryctolagus cuniculus	81.60	0.00e+00	792.00
IUUC-Oba-075633	Oryza barthii	42.08	2.00e-107	382.00
IUUC-Obr-076423	Oryza brachyantha	42.59	1.00e-109	389.00
IUUC-Ogl-077913	Oryza glaberrima	41.56	5.00e-110	390.00
IUUC-Ogu-078435	Oryza glumaepatula	42.08	2.00e-107	382.00
IUUC-Oin-080072	Oryza indica	42.08	2.00e-107	382.00
IUUC-Olo-080535	Oryza longistaminata	38.21	1.00e-90	326.00
IUUC-Ome-081309	Oryza meridionalis	42.08	2.00e-107	382.00
IUUC-Oni-083113	Oryza nivara	42.08	2.00e-107	382.00
IUUC-Opu-083168	Oryza punctata	41.54	4.00e-103	368.00
IUUC-Oru-084253	Oryza rufipogon	42.08	2.00e-107	382.00
IUUC-Osa-085554	Oryza sativa	41.56	5.00e-110	391.00
IUUC-Ola-086998	Oryzias latipes	82.52	0.00e+00	801.00
IUUC-Olu-087818	Ostreococcus lucimarinus	36.61	6.00e-70	258.00
IUUC-Oga-088571	Otolemur garnettii	82.82	0.00e+00	813.00
IUUC-Oar-089526	Ovis aries	82.86	0.00e+00	814.00
IUUC-Ptr-091433	Pan troglodytes	82.45	0.00e+00	796.00
IUUC-Pan-091966	Papio anubis	82.45	0.00e+00	796.00
IUUC-Psi-093458	Pelodiscus sinensis	83.48	0.00e+00	792.00
IUUC-Pma-094343	Petromyzon marinus	67.70	1.00e-118	419.00
IUUC-Pno-095109	Phaeosphaeria nodorum	38.80	7.00e-65	241.00
IUUC-Ppa-095756	Physcomitrella patens	42.23	8.00e-110	390.00
IUUC-Pfo-096514	Poecilia formosa	84.69	0.00e+00	794.00
IUUC-Pab-098477	Pongo abelii	71.86	2.00e-180	624.00
IUUC-Pop-099221	Populus trichocarpa	40.48	3.00e-102	365.00
IUUC-Pca-100791	Procavia capensis	68.24	2.00e-150	525.00
IUUC-Ppe-101812	Prunus persica	40.82	7.00e-106	377.00
IUUC-Pva-102462	Pteropus vampyrus	78.45	0.00e+00	659.00
IUUC-Pgr-103623	Puccinia graminis	41.04	2.00e-75	276.00
IUUC-Ptt-103767	Puccinia triticina	38.86	5.00e-68	251.00
IUUC-Pte-104109	Pyrenophora teres	40.68	3.00e-69	256.00
IUUC-Pyt-104766	Pyrenophora triticirepentis	40.69	2.00e-68	253.00
IUUC-Rno-105351	Rattus norvegicus	80.20	0.00e+00	776.00
IUUC-Sce-106168	Saccharomyces cerevisiae	33.33	2.00e-60	226.00
IUUC-Sha-107491	Sarcophilus harrisii	83.91	0.00e+00	818.00
IUUC-Sja-107769	Schizosaccharomyces japonicus	33.93	1.00e-77	283.00
IUUC-Spo-108174	Schizosaccharomyces pombe	38.43	3.00e-81	295.00
IUUC-Ssl-108659	Sclerotinia sclerotiorum	36.06	2.00e-83	303.00
IUUC-Smo-108805	Selaginella moellendorffii	42.98	8.00e-107	380.00
IUUC-Sit-110361	Setaria italica	41.60	2.00e-110	392.00
IUUC-Sly-110965	Solanum lycopersicum	39.57	1.00e-104	373.00
IUUC-Sar-113355	Sorex araneus	81.62	2.00e-141	495.00
IUUC-Sbi-114778	Sorghum bicolor	42.21	1.00e-108	386.00
IUUC-Sre-115011	Sporisorium reilianum	37.74	4.00e-62	232.00
IUUC-Ssc-116273	Sus scrofa	82.24	0.00e+00	801.00
IUUC-Tgu-117063	Taeniopygia guttata	84.09	0.00e+00	809.00
IUUC-Tru-118381	Takifugu rubripes	82.86	0.00e+00	811.00
IUUC-Tsy-119076	Tarsius syrichta	69.32	2.00e-99	355.00
IUUC-Tni-119941	Tetraodon nigroviridis	84.33	0.00e+00	804.00
IUUC-Tca-121246	Theobroma cacao	40.56	6.00e-105	374.00
IUUC-Tre-121969	Trichoderma reesei	39.27	1.00e-69	257.00
IUUC-Tvi-122543	Trichoderma virens	35.36	1.00e-80	293.00
IUUC-Tae-125744	Triticum aestivum	42.80	1.00e-109	389.00
IUUC-Tur-126128	Triticum urartu	40.39	2.00e-37	150.00
IUUC-Tbe-128030	Tupaia belangeri	76.13	0.00e+00	721.00
IUUC-Ttr-128701	Tursiops truncatus	81.52	0.00e+00	659.00
IUUC-Uma-129657	Ustilago maydis	38.07	5.00e-66	245.00
IUUC-Vda-129723	Verticillium dahliae	37.47	2.00e-63	236.00
IUUC-Vpa-130284	Vicugna pacos	59.67	1.00e-152	533.00
IUUC-Vvi-131037	Vitis vinifera	41.55	1.00e-108	386.00
IUUC-Xtr-132235	Xenopus tropicalis	80.82	0.00e+00	833.00
IUUC-Xma-133840	Xiphophorus maculatus	84.69	0.00e+00	819.00
IUUC-Yli-134453	Yarrowia lipolytica	38.60	2.00e-85	309.00
IUUC-Zma-135669	Zea mays	35.37	2.00e-91	329.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence