iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oan-073635

UUCD1 version

UUC-OrA-00860

Ensembl Protein ID

ENSOANP00000011808.3

UniProt Accession

F6YP63; F6YP63_ORNAN

Protein Name

Uncharacterized protein

Gene Name

USP14

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000007418.3	ENSOANT00000011810.3	ENSOANP00000011808.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.10e-64	219.0	39	413

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefs.... 85
           +Gl+NlgNtCYmN+++Qc+ ++pel+e+l++ +  +l+++ +  + + ++ +l++lf ++ +++++++ p  ll+ l+++ ++f     
   Q: 39   CGLTNLGNTCYMNATVQCIRSVPELKEALKR-YAGALRASGEMASAQYITAALRDLFDSM-DKSSSSIPPIILLQFLHMAFPQFAekgd 125
           7******************************.****************************.99999******************99*** PP
   S: 86   ..gyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldl 172
             +y qqDa+E++ +++  l+++l        e +e++++ e+++ +    + k+ksli++ F +++++++kc e +++  ++ + ++l
   Q: 126  qgQYLQQDANECWVHVMRVLQQKL--------EALEGDSDMETDSGSTAAAPPKKKSLIDQFFSVEFETTMKCTEAEEEEATKGKENQL 206
           999*********************........56888888888899999*******************************999988888 PP
   S: 173  slpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdl 261
           +l+   ++e   + l   L+   +ee  +     ++++ +++    k+ k+++lP +L++++ Rf ++e+++++ k+ k v+fpl+Ld+
   Q: 207  QLSCFINQEV--KYLFTGLKLRLQEEITK-----QSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKGSVNAKVLKDVKFPLMLDV 288
           8888877754..58999999999999998.....58899999999******************************************** PP
   S: 262  spfcts.....................peekqke..............................kkkYeLiavvvHsG.slssGHYvay 298
            + ct                      +     +                              +  Y+L av+ H+G s+ssGHYv++
   Q: 289  YELCTPelqekmvsfrskfkdledkkvN-----QqpkktnkgsgtqkevkyepfsfpddigsnnCGYYDLQAVLTHQGrSSSSGHYVSW 372
           ******6666666666666666555550.....0555555666666677777777777777777************************* PP
   S: 299  vknekgkWllfdDskVtevkeeevleetg....staYvlfY 335
           vk ++++W++fdD+kV+ v+ +++l+ +g    + aYvl+Y
   Q: 373  VKRKQEEWIKFDDDKVSIVTPDDILRLSGggdwHIAYVLLY 413
           **************************988************ PP

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

MTLLMMGSAD ALPEEPVART VFVEDMTEEQ LASAMELPCG LTNLGNTCYM NATVQCIRSV 60
PELKEALKRY AGALRASGEM ASAQYITAAL RDLFDSMDKS SSSIPPIILL QFLHMAFPQF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCCGTCAACA ACAAAGTGCC GATTCTCACC GTTTCCATCC GGATAATCAT TTTTGTCTCT 60
CAAACAGGGA ATGACTCTTC TGATGATGGG TTCAGCCGAC GCTCTTCCCG AGGAGCCTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0009986--C:cell surface
GO:0031410--C:cytoplasmic vesicle
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0045202--C:synapse
GO:0004866--F:endopeptidase inhibitor activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0007268--P:chemical synaptic transmission
GO:1903070--P:negative regulation of ER-associated ubiquitin-dependent protein catabolic process
GO:0016579--P:protein deubiquitination
GO:0050920--P:regulation of chemotaxis
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000893	Aegilops tauschii	29.97	1.00e-33	137.00
IUUC-Aml-002053	Ailuropoda melanoleuca	91.82	0.00e+00	756.00
IUUC-Atr-002725	Amborella trichopoda	37.79	8.00e-75	273.00
IUUC-Apl-004031	Anas platyrhynchos	91.80	0.00e+00	780.00
IUUC-Aca-004361	Anolis carolinensis	89.74	0.00e+00	774.00
IUUC-Aly-006078	Arabidopsis lyrata	38.99	1.00e-85	310.00
IUUC-Ath-007623	Arabidopsis thaliana	39.45	1.00e-85	309.00
IUUC-Ago-007796	Ashbya gossypii	31.18	1.00e-51	196.00
IUUC-Acl-008258	Aspergillus clavatus	36.50	5.00e-53	201.00
IUUC-Afl-008732	Aspergillus flavus	31.96	2.00e-60	226.00
IUUC-Afu-008755	Aspergillus fumigatus	34.64	3.00e-68	252.00
IUUC-Ani-009148	Aspergillus nidulans	32.94	3.00e-60	225.00
IUUC-Ang-009878	Aspergillus niger	35.96	2.00e-51	196.00
IUUC-Aor-010239	Aspergillus oryzae	31.96	2.00e-60	226.00
IUUC-Ate-010243	Aspergillus terreus	32.87	1.00e-63	237.00
IUUC-Ame-011327	Astyanax mexicanus	47.22	4.00e-97	347.00
IUUC-Bgr-012231	Blumeria graminis	31.70	1.00e-54	206.00
IUUC-Bta-012553	Bos taurus	91.12	0.00e+00	766.00
IUUC-Bci-013606	Botrytis cinerea	38.56	4.00e-55	208.00
IUUC-Bdi-014567	Brachypodium distachyon	40.09	7.00e-86	310.00
IUUC-Bol-016127	Brassica oleracea	39.35	6.00e-88	317.00
IUUC-Bra-017501	Brassica rapa	39.12	5.00e-87	314.00
IUUC-Cel-018140	Caenorhabditis elegans	38.14	7.00e-79	287.00
IUUC-Cja-019516	Callithrix jacchus	90.70	0.00e+00	764.00
IUUC-Cfa-020808	Canis familiaris	92.06	0.00e+00	775.00
IUUC-Cpo-021688	Cavia porcellus	91.57	0.00e+00	774.00
IUUC-Cre-022663	Chlamydomonas reinhardtii	35.65	1.00e-58	219.00
IUUC-Csa-023429	Chlorocebus sabaeus	91.10	0.00e+00	749.00
IUUC-Cho-024347	Choloepus hoffmanni	91.57	0.00e+00	770.00
IUUC-Cin-025198	Ciona intestinalis	51.86	3.00e-124	438.00
IUUC-Csv-026007	Ciona savignyi	51.40	6.00e-124	437.00
IUUC-Cgl-026757	Colletotrichum gloeosporioides	37.93	7.00e-50	191.00
IUUC-Cne-026963	Cryptococcus neoformans	33.79	9.00e-72	263.00
IUUC-Cme-027240	Cyanidioschyzon merolae	34.26	2.00e-55	209.00
IUUC-Dre-027647	Danio rerio	82.98	0.00e+00	704.00
IUUC-Dno-029967	Dasypus novemcinctus	91.36	0.00e+00	754.00
IUUC-Dor-030886	Dipodomys ordii	85.28	0.00e+00	690.00
IUUC-Dse-031466	Dothistroma septosporum	36.34	4.00e-47	182.00
IUUC-Dme-032079	Drosophila melanogaster	53.48	5.00e-129	453.00
IUUC-Ete-032351	Echinops telfairi	80.80	0.00e+00	679.00
IUUC-Eca-033461	Equus caballus	91.36	0.00e+00	800.00
IUUC-Eeu-035220	Erinaceus europaeus	71.90	2.00e-172	597.00
IUUC-Fca-036210	Felis catus	92.06	0.00e+00	776.00
IUUC-Fal-037528	Ficedula albicollis	91.80	0.00e+00	763.00
IUUC-Fox-037805	Fusarium oxysporum	38.99	5.00e-55	207.00
IUUC-Fso-038177	Fusarium solani	36.74	2.00e-51	196.00
IUUC-Gmo-038953	Gadus morhua	78.54	0.00e+00	630.00
IUUC-Ggr-039972	Gaeumannomyces graminis	34.04	7.00e-61	227.00
IUUC-Gga-040462	Gallus gallus	90.87	0.00e+00	769.00
IUUC-Gac-041312	Gasterosteus aculeatus	80.09	0.00e+00	676.00
IUUC-Gma-043255	Glycine max	41.01	6.00e-86	310.00
IUUC-Ggo-045458	Gorilla gorilla	74.88	9.00e-180	622.00
IUUC-Hsa-045706	Homo sapiens	91.36	0.00e+00	753.00
IUUC-Hvu-047821	Hordeum vulgare	43.62	8.00e-33	133.00
IUUC-Itr-048654	Ictidomys tridecemlineatus	89.72	0.00e+00	759.00
IUUC-Lch-050464	Latimeria chalumnae	81.41	0.00e+00	698.00
IUUC-Lpe-051419	Leersia perrieri	39.10	7.00e-81	293.00
IUUC-Loc-052732	Lepisosteus oculatus	81.78	0.00e+00	716.00
IUUC-Lma-053177	Leptosphaeria maculans	38.94	8.00e-55	207.00
IUUC-Laf-053822	Loxodonta africana	92.27	0.00e+00	773.00
IUUC-Mcc-055893	Macaca mulatta	91.33	0.00e+00	750.00
IUUC-Meu-056307	Macropus eugenii	79.30	0.00e+00	667.00
IUUC-Mor-057171	Magnaporthe oryzae	37.54	4.00e-52	198.00
IUUC-Mpo-057415	Magnaporthe poae	39.56	8.00e-56	210.00
IUUC-Mtr-057901	Medicago truncatula	41.47	9.00e-88	317.00
IUUC-Mla-058897	Melampsora laricipopulina	38.51	7.00e-55	207.00
IUUC-Mga-060016	Meleagris gallopavo	92.27	0.00e+00	783.00
IUUC-Mvi-060562	Microbotryum violaceum	38.71	1.00e-54	206.00
IUUC-Mmr-060624	Microcebus murinus	91.12	0.00e+00	796.00
IUUC-Mdo-061809	Monodelphis domestica	93.02	0.00e+00	768.00
IUUC-Mmu-063869	Mus musculus	90.42	0.00e+00	761.00
IUUC-Mac-064876	Musa acuminata	35.90	2.00e-69	256.00
IUUC-Mpu-066480	Mustela putorius furo	91.59	0.00e+00	772.00
IUUC-Mlu-067866	Myotis lucifugus	90.42	0.00e+00	776.00
IUUC-Nfi-068393	Neosartorya fischeri	36.41	2.00e-53	202.00
IUUC-Ncr-068815	Neurospora crassa	34.02	9.00e-64	237.00
IUUC-Nle-069741	Nomascus leucogenys	90.96	5.00e-90	322.00
IUUC-Opr-070712	Ochotona princeps	73.30	3.00e-166	577.00
IUUC-Ont-071544	Oreochromis niloticus	80.90	0.00e+00	641.00
IUUC-Ocu-074926	Oryctolagus cuniculus	91.10	0.00e+00	752.00
IUUC-Oba-075633	Oryza barthii	39.42	4.00e-80	291.00
IUUC-Obr-076423	Oryza brachyantha	40.00	2.00e-83	302.00
IUUC-Ogl-077913	Oryza glaberrima	39.02	1.00e-82	299.00
IUUC-Ogu-078435	Oryza glumaepatula	39.42	4.00e-80	291.00
IUUC-Oin-080072	Oryza indica	39.42	5.00e-80	291.00
IUUC-Olo-080535	Oryza longistaminata	36.05	4.00e-65	241.00
IUUC-Ome-081309	Oryza meridionalis	39.42	4.00e-80	291.00
IUUC-Oni-083113	Oryza nivara	39.42	4.00e-80	291.00
IUUC-Opu-083168	Oryza punctata	38.94	4.00e-80	291.00
IUUC-Oru-084253	Oryza rufipogon	39.42	4.00e-80	291.00
IUUC-Osa-085554	Oryza sativa	39.02	9.00e-83	300.00
IUUC-Ola-086998	Oryzias latipes	80.05	0.00e+00	665.00
IUUC-Olu-087818	Ostreococcus lucimarinus	37.12	2.00e-62	233.00
IUUC-Oga-088571	Otolemur garnettii	91.33	0.00e+00	775.00
IUUC-Oar-089526	Ovis aries	91.36	0.00e+00	768.00
IUUC-Ptr-091433	Pan troglodytes	91.33	0.00e+00	750.00
IUUC-Pan-091966	Papio anubis	91.10	0.00e+00	749.00
IUUC-Psi-093458	Pelodiscus sinensis	91.49	0.00e+00	773.00
IUUC-Pma-094343	Petromyzon marinus	64.00	2.00e-81	294.00
IUUC-Pno-095109	Phaeosphaeria nodorum	37.31	1.00e-51	197.00
IUUC-Ppa-095756	Physcomitrella patens	41.40	9.00e-90	323.00
IUUC-Pfo-096514	Poecilia formosa	81.37	0.00e+00	660.00
IUUC-Pab-098477	Pongo abelii	85.86	0.00e+00	635.00
IUUC-Pop-099221	Populus trichocarpa	37.93	4.00e-79	288.00
IUUC-Pca-100791	Procavia capensis	74.53	1.00e-164	572.00
IUUC-Ppe-101812	Prunus persica	38.79	1.00e-83	303.00
IUUC-Pva-102462	Pteropus vampyrus	86.45	0.00e+00	723.00
IUUC-Pgr-103623	Puccinia graminis	40.43	1.00e-54	206.00
IUUC-Ptt-103767	Puccinia triticina	39.02	1.00e-56	213.00
IUUC-Pte-104109	Pyrenophora teres	38.55	1.00e-54	207.00
IUUC-Pyt-104766	Pyrenophora triticirepentis	39.45	5.00e-55	208.00
IUUC-Rno-105351	Rattus norvegicus	88.55	0.00e+00	727.00
IUUC-Sce-106168	Saccharomyces cerevisiae	31.70	2.00e-53	202.00
IUUC-Sha-107491	Sarcophilus harrisii	93.71	0.00e+00	789.00
IUUC-Sja-107769	Schizosaccharomyces japonicus	34.85	6.00e-69	254.00
IUUC-Spo-108174	Schizosaccharomyces pombe	36.07	3.00e-63	235.00
IUUC-Ssl-108659	Sclerotinia sclerotiorum	32.73	6.00e-68	251.00
IUUC-Smo-108805	Selaginella moellendorffii	40.62	6.00e-85	307.00
IUUC-Sit-110361	Setaria italica	40.23	3.00e-85	308.00
IUUC-Sly-110965	Solanum lycopersicum	37.96	3.00e-82	298.00
IUUC-Sar-113355	Sorex araneus	79.63	0.00e+00	634.00
IUUC-Sbi-114778	Sorghum bicolor	41.18	1.00e-86	313.00
IUUC-Sre-115011	Sporisorium reilianum	37.46	6.00e-49	187.00
IUUC-Ssc-116273	Sus scrofa	90.63	0.00e+00	757.00
IUUC-Tgu-117063	Taeniopygia guttata	91.33	0.00e+00	762.00
IUUC-Tru-118381	Takifugu rubripes	78.40	0.00e+00	661.00
IUUC-Tsy-119076	Tarsius syrichta	76.28	8.00e-111	392.00
IUUC-Tni-119941	Tetraodon nigroviridis	79.67	0.00e+00	649.00
IUUC-Tca-121246	Theobroma cacao	38.99	1.00e-84	306.00
IUUC-Tre-121969	Trichoderma reesei	36.07	6.00e-50	191.00
IUUC-Tvi-122543	Trichoderma virens	32.53	5.00e-60	224.00
IUUC-Tae-125484	Triticum aestivum	40.24	4.00e-83	301.00
IUUC-Tur-126128	Triticum urartu	32.18	4.00e-36	145.00
IUUC-Tbe-128030	Tupaia belangeri	83.18	0.00e+00	680.00
IUUC-Ttr-128701	Tursiops truncatus	89.86	0.00e+00	732.00
IUUC-Uma-129657	Ustilago maydis	36.67	6.00e-52	197.00
IUUC-Vda-129723	Verticillium dahliae	34.78	4.00e-43	168.00
IUUC-Vpa-130284	Vicugna pacos	65.19	6.00e-153	533.00
IUUC-Vvi-131037	Vitis vinifera	39.95	3.00e-85	308.00
IUUC-Xtr-132235	Xenopus tropicalis	85.78	0.00e+00	748.00
IUUC-Xma-133840	Xiphophorus maculatus	81.37	0.00e+00	685.00
IUUC-Yli-134453	Yarrowia lipolytica	35.09	2.00e-64	239.00
IUUC-Zma-135669	Zea mays	33.88	2.00e-69	255.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence