iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Xtr-132235

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAMC01030540

Gene Name

usp14

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000003152.3	ENSXETT00000006853.3	ENSXETP00000006853.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.20e-62	212.3	105	478
ULD/UDP/UBQ/UBQ_Other	1.20e-08	34.8	6	74

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefs.... 85
           +Gl+NlgNtCYmN+++Qc+ ++pel+e+l++ +  +l+++ +  + + ++ +l++lf ++ +++++++ p  ll+ l+++ ++f     
   Q: 105  CGLTNLGNTCYMNATVQCIRSVPELKEALKR-YAGALRASGEMASAQYITAALRDLFDSM-DKTSSSIPPIILLQFLHMAFPQFAekgd 191
           7******************************.****************************.99999******************99*** PP
   S: 86   ..gyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlk..sqikclecdnvssreepfl 170
             +y qqDa+E++ +++  l+++l         e+ e d+   +d+    + +k++s+i++ F+++++  +++kc e + + +++++ +
   Q: 192  qgQYLQQDANECWVQVMRVLQQKL---------EAIEGDSDMETDSGAAATASKKNSFIDQFFGIEFEstKSMKCTESEDEEVTKSKET 271
           999*********************.........444555555566778999999*********99998446789999988887777766 PP
   S: 171  dlslpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleL 259
           +l+l+   ++e   + l   L+   +ee  +     ++++ +++    k+ ++++lP +L++++ Rf ++e+++++ k+ k v+fpl+L
   Q: 272  QLQLSCFINQEV--KYLFTGLKLRLQEEITK-----FSPSLQRNALYIKTSRISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLML 353
           666666666643..47999999999988887.....8999999999******************************************* PP
   S: 260  dlspfcts.....peekqke............................................kkkYeLiavvvHsG.slssGHYvay 298
           d+ + ct            +                                            +  YeL av+ H+G s+ssGHYv++
   Q: 354  DIYELCTPelqekM-----VsyrskfkqledkkgseqapkanqmsqrevryepyafpgdvgsinSGYYELQAVLTHQGrSSSSGHYVSW 437
           *******9444440.....3566666666666666777778888889999999999999999999************************ PP
   S: 299  vknekgkWllfdDskVtevkeeevleetg....staYvlfY 335
           vk ++++W++fdD+kV+ v+ e++l+ +g    + aYvl+Y
   Q: 438  VKRKHDEWIKFDDDKVSIVSPEDILRLSGggdwHIAYVLLY 478
           **************************988************ PP

ULD/UDP/UBQ/UBQ_Other

   S: 3    vtvksldgseltlkvnpsdtVaeLKekiekklgippeqqrLiykGkiLeddktLadyglkdgstihllek 72
           v vk+ + +   +++n +++  ++K +++ ++g++p++q+ ++kG  L+dd +++ +++k g+t++++ +
   Q: 6    VNVKWGKEKFDNVELNTDEPPMVFKAQLFALTGVQPDRQKVMVKGGTLKDD-DWGTLKIKSGMTLLMMGS 74
           7899999998899***********************************999.9**************976 PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

MPLYSVNVKW GKEKFDNVEL NTDEPPMVFK AQLFALTGVQ PDRQKVMVKG GTLKDDDWGT 60
LKIKSGMTLL MMGSAEALPE EPAVRPVFVE DMTEEQLASA MELPCGLTNL GNTCYMNATV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGATCCTGTA TCGGAGGTCG GGACTATCTC AGCATGCCCC TGTATTCAGG TATTGGAGAC 60
ACAGATTACA GTTTGGAGAT TCTTTACACG CGACCCTCCG TCCTTTGCTG AACTACAGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR029071--Ubiquitin-rel_dom
IPR019954--Ubiquitin_CS
IPR000626--Ubiquitin_dom
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00299--UBIQUITIN_1
PS50053--UBIQUITIN_2
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

SMART

SM00213--UBQ

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000893	Aegilops tauschii	43.41	2.00e-38	153.00
IUUC-Aml-002053	Ailuropoda melanoleuca	85.19	0.00e+00	823.00
IUUC-Atr-002725	Amborella trichopoda	40.88	5.00e-100	357.00
IUUC-Apl-004031	Anas platyrhynchos	87.02	0.00e+00	863.00
IUUC-Aca-004361	Anolis carolinensis	86.52	0.00e+00	878.00
IUUC-Aly-006176	Arabidopsis lyrata	41.41	6.00e-109	387.00
IUUC-Ath-007623	Arabidopsis thaliana	41.12	4.00e-108	384.00
IUUC-Ago-007796	Ashbya gossypii	32.16	4.00e-56	212.00
IUUC-Acl-008258	Aspergillus clavatus	38.21	1.00e-66	247.00
IUUC-Afl-008732	Aspergillus flavus	34.45	2.00e-77	283.00
IUUC-Afu-008755	Aspergillus fumigatus	38.15	2.00e-68	253.00
IUUC-Ani-009148	Aspergillus nidulans	39.30	5.00e-72	265.00
IUUC-Ang-009878	Aspergillus niger	33.45	5.00e-71	261.00
IUUC-Aor-010239	Aspergillus oryzae	34.45	2.00e-77	283.00
IUUC-Ate-010243	Aspergillus terreus	33.81	1.00e-69	257.00
IUUC-Ame-011327	Astyanax mexicanus	51.00	1.00e-124	439.00
IUUC-Bgr-012231	Blumeria graminis	33.98	2.00e-75	276.00
IUUC-Bta-012553	Bos taurus	84.68	0.00e+00	840.00
IUUC-Bci-013606	Botrytis cinerea	39.37	8.00e-69	254.00
IUUC-Bdi-014567	Brachypodium distachyon	42.91	9.00e-111	393.00
IUUC-Bol-015565	Brassica oleracea	40.76	1.00e-108	386.00
IUUC-Bra-017297	Brassica rapa	40.52	3.00e-107	382.00
IUUC-Cel-018140	Caenorhabditis elegans	42.66	5.00e-100	357.00
IUUC-Cja-019516	Callithrix jacchus	85.86	0.00e+00	851.00
IUUC-Cfa-020808	Canis familiaris	85.48	0.00e+00	848.00
IUUC-Cpo-021688	Cavia porcellus	84.44	0.00e+00	833.00
IUUC-Cre-022663	Chlamydomonas reinhardtii	39.44	8.00e-87	313.00
IUUC-Csa-023429	Chlorocebus sabaeus	85.25	0.00e+00	826.00
IUUC-Cho-024347	Choloepus hoffmanni	84.44	0.00e+00	837.00
IUUC-Cin-025198	Ciona intestinalis	54.21	7.00e-151	526.00
IUUC-Csv-026007	Ciona savignyi	53.02	7.00e-153	533.00
IUUC-Cgl-026757	Colletotrichum gloeosporioides	41.46	6.00e-66	244.00
IUUC-Cne-026963	Cryptococcus neoformans	35.79	5.00e-76	278.00
IUUC-Cme-027240	Cyanidioschyzon merolae	31.43	5.00e-62	231.00
IUUC-Dre-027647	Danio rerio	81.97	0.00e+00	829.00
IUUC-Dno-029967	Dasypus novemcinctus	84.27	0.00e+00	823.00
IUUC-Dor-030886	Dipodomys ordii	77.60	0.00e+00	665.00
IUUC-Dse-031466	Dothistroma septosporum	36.27	8.00e-58	218.00
IUUC-Dme-032079	Drosophila melanogaster	55.14	9.00e-157	546.00
IUUC-Ete-032351	Echinops telfairi	77.13	0.00e+00	770.00
IUUC-Eca-033461	Equus caballus	84.68	0.00e+00	876.00
IUUC-Eeu-035220	Erinaceus europaeus	65.30	4.00e-175	607.00
IUUC-Fca-036210	Felis catus	85.28	0.00e+00	847.00
IUUC-Fal-037528	Ficedula albicollis	86.64	0.00e+00	842.00
IUUC-Fox-037805	Fusarium oxysporum	40.93	1.00e-70	260.00
IUUC-Fso-038177	Fusarium solani	39.22	1.00e-67	250.00
IUUC-Gmo-038953	Gadus morhua	78.82	0.00e+00	767.00
IUUC-Ggr-039972	Gaeumannomyces graminis	38.38	2.00e-65	243.00
IUUC-Gga-040462	Gallus gallus	85.63	0.00e+00	856.00
IUUC-Gac-041312	Gasterosteus aculeatus	79.63	0.00e+00	791.00
IUUC-Gma-043255	Glycine max	41.85	1.00e-106	379.00
IUUC-Ggo-045458	Gorilla gorilla	72.47	0.00e+00	699.00
IUUC-Hsa-045706	Homo sapiens	85.48	0.00e+00	830.00
IUUC-Hvu-047821	Hordeum vulgare	47.22	1.00e-57	216.00
IUUC-Itr-048654	Ictidomys tridecemlineatus	83.87	0.00e+00	848.00
IUUC-Lch-050464	Latimeria chalumnae	80.82	0.00e+00	814.00
IUUC-Lpe-051419	Leersia perrieri	42.27	2.00e-107	382.00
IUUC-Loc-052732	Lepisosteus oculatus	80.16	0.00e+00	832.00
IUUC-Lma-053177	Leptosphaeria maculans	41.55	1.00e-70	260.00
IUUC-Laf-053822	Loxodonta africana	84.44	0.00e+00	836.00
IUUC-Mcc-055893	Macaca mulatta	85.45	0.00e+00	827.00
IUUC-Meu-056307	Macropus eugenii	77.28	0.00e+00	746.00
IUUC-Mor-057171	Magnaporthe oryzae	39.11	1.00e-67	250.00
IUUC-Mpo-057415	Magnaporthe poae	39.52	7.00e-71	261.00
IUUC-Mtr-057901	Medicago truncatula	42.43	4.00e-110	391.00
IUUC-Mla-058897	Melampsora laricipopulina	39.89	6.00e-75	274.00
IUUC-Mga-060016	Meleagris gallopavo	86.18	0.00e+00	860.00
IUUC-Mvi-060562	Microbotryum violaceum	40.61	2.00e-68	252.00
IUUC-Mmr-060624	Microcebus murinus	85.48	0.00e+00	880.00
IUUC-Mdo-061809	Monodelphis domestica	85.34	0.00e+00	841.00
IUUC-Mmu-063869	Mus musculus	84.27	0.00e+00	837.00
IUUC-Mac-064876	Musa acuminata	39.88	3.00e-96	345.00
IUUC-Mpu-066480	Mustela putorius furo	85.08	0.00e+00	845.00
IUUC-Mlu-067866	Myotis lucifugus	84.07	0.00e+00	844.00
IUUC-Nfi-068393	Neosartorya fischeri	37.24	5.00e-66	245.00
IUUC-Ncr-068815	Neurospora crassa	40.69	5.00e-71	261.00
IUUC-Nle-070121	Nomascus leucogenys	88.93	2.00e-128	451.00
IUUC-Opr-070712	Ochotona princeps	66.98	1.00e-152	533.00
IUUC-Ont-071544	Oreochromis niloticus	78.66	0.00e+00	753.00
IUUC-Oan-073635	Ornithorhynchus anatinus	85.08	0.00e+00	708.00
IUUC-Ocu-074926	Oryctolagus cuniculus	85.25	0.00e+00	830.00
IUUC-Oba-075633	Oryza barthii	42.06	6.00e-107	380.00
IUUC-Obr-076423	Oryza brachyantha	42.83	3.00e-109	388.00
IUUC-Ogl-077913	Oryza glaberrima	42.22	7.00e-110	390.00
IUUC-Ogu-078435	Oryza glumaepatula	42.06	6.00e-107	380.00
IUUC-Oin-080072	Oryza indica	42.03	4.00e-107	381.00
IUUC-Olo-080535	Oryza longistaminata	38.92	3.00e-92	331.00
IUUC-Ome-081309	Oryza meridionalis	42.06	6.00e-107	380.00
IUUC-Oni-083113	Oryza nivara	42.06	6.00e-107	380.00
IUUC-Opu-083168	Oryza punctata	40.70	1.00e-100	360.00
IUUC-Oru-084253	Oryza rufipogon	42.06	6.00e-107	380.00
IUUC-Osa-085554	Oryza sativa	42.22	8.00e-110	390.00
IUUC-Ola-086998	Oryzias latipes	78.95	0.00e+00	781.00
IUUC-Olu-087818	Ostreococcus lucimarinus	36.92	4.00e-70	258.00
IUUC-Oga-088571	Otolemur garnettii	85.66	0.00e+00	847.00
IUUC-Oar-089526	Ovis aries	84.65	0.00e+00	835.00
IUUC-Ptr-091433	Pan troglodytes	85.45	0.00e+00	827.00
IUUC-Pan-091966	Papio anubis	85.25	0.00e+00	826.00
IUUC-Psi-093458	Pelodiscus sinensis	85.56	0.00e+00	815.00
IUUC-Pma-094343	Petromyzon marinus	68.38	7.00e-120	422.00
IUUC-Pno-095109	Phaeosphaeria nodorum	34.14	3.00e-75	276.00
IUUC-Ppa-095756	Physcomitrella patens	43.22	1.00e-110	393.00
IUUC-Pfo-096514	Poecilia formosa	81.10	0.00e+00	771.00
IUUC-Pab-098477	Pongo abelii	74.36	0.00e+00	646.00
IUUC-Pop-099221	Populus trichocarpa	41.16	9.00e-103	367.00
IUUC-Pca-100791	Procavia capensis	68.53	3.00e-155	540.00
IUUC-Ppe-101812	Prunus persica	41.41	2.00e-106	379.00
IUUC-Pva-102462	Pteropus vampyrus	79.35	0.00e+00	673.00
IUUC-Pgr-103623	Puccinia graminis	41.83	2.00e-75	276.00
IUUC-Ptt-103767	Puccinia triticina	40.00	2.00e-67	249.00
IUUC-Pte-104109	Pyrenophora teres	40.94	1.00e-71	263.00
IUUC-Pyt-104766	Pyrenophora triticirepentis	41.07	5.00e-71	261.00
IUUC-Rno-105351	Rattus norvegicus	83.27	0.00e+00	809.00
IUUC-Sce-106168	Saccharomyces cerevisiae	32.60	2.00e-59	223.00
IUUC-Sha-107491	Sarcophilus harrisii	86.14	0.00e+00	856.00
IUUC-Sja-107769	Schizosaccharomyces japonicus	34.71	5.00e-79	288.00
IUUC-Spo-108174	Schizosaccharomyces pombe	37.03	2.00e-78	286.00
IUUC-Ssl-108659	Sclerotinia sclerotiorum	34.56	2.00e-81	296.00
IUUC-Smo-108805	Selaginella moellendorffii	44.88	2.00e-111	395.00
IUUC-Sit-110361	Setaria italica	42.66	3.00e-113	401.00
IUUC-Sly-110965	Solanum lycopersicum	40.92	6.00e-107	380.00
IUUC-Sar-113355	Sorex araneus	87.04	7.00e-153	533.00
IUUC-Sbi-114778	Sorghum bicolor	43.15	3.00e-110	392.00
IUUC-Sre-115011	Sporisorium reilianum	37.16	2.00e-63	236.00
IUUC-Ssc-116273	Sus scrofa	83.57	0.00e+00	820.00
IUUC-Tgu-117063	Taeniopygia guttata	86.21	0.00e+00	840.00
IUUC-Tru-118381	Takifugu rubripes	78.34	0.00e+00	784.00
IUUC-Tsy-119076	Tarsius syrichta	67.84	8.00e-98	350.00
IUUC-Tni-119941	Tetraodon nigroviridis	79.84	0.00e+00	779.00
IUUC-Tca-121246	Theobroma cacao	42.15	4.00e-109	388.00
IUUC-Tre-121969	Trichoderma reesei	38.39	6.00e-68	251.00
IUUC-Tvi-122543	Trichoderma virens	33.92	4.00e-74	272.00
IUUC-Tae-125484	Triticum aestivum	43.03	5.00e-109	387.00
IUUC-Tur-126128	Triticum urartu	42.36	3.00e-39	155.00
IUUC-Tbe-128030	Tupaia belangeri	76.73	0.00e+00	737.00
IUUC-Ttr-128701	Tursiops truncatus	83.10	0.00e+00	690.00
IUUC-Uma-129657	Ustilago maydis	38.48	3.00e-67	249.00
IUUC-Vda-129723	Verticillium dahliae	33.80	8.00e-72	264.00
IUUC-Vpa-130284	Vicugna pacos	60.20	7.00e-156	543.00
IUUC-Vvi-131037	Vitis vinifera	42.77	2.00e-109	389.00
IUUC-Xma-133840	Xiphophorus maculatus	81.10	0.00e+00	799.00
IUUC-Yli-134453	Yarrowia lipolytica	36.98	7.00e-82	297.00
IUUC-Zma-135669	Zea mays	36.53	2.00e-94	339.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence