iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ocu-073796

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAGW02059888

Gene Name

USP48

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000007800.3	ENSOCUT00000007808.3	ENSOCUP00000006749.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	3.00e-64	217.4	9	292
ULD/UDP/UBQ/UBQ_Other	8.30e-11	41.7	818	880

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 41   npkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde 129
           +++ + ++++++lq lf+ l++s++++++p+ ++kal+     +++ +qqDaqEf + +++ le++l                      
   Q: 9    ERDYEPQTICEHLQYLFALLQNSNRRYIDPSGFVKALG-----LDTGQQQDAQEFSKLFMSLLEDTL---------------------- 70
           4567889******************************9.....78899*******************...................... PP
   S: 130  aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeae 218
            +++k+   ++++++ F g++   ++c++c+++s+  ++f++l+l+++g++     +l+dc+++f kee+leg+n+y+ce+c++kq+a+
   Q: 71   -SKQKNPDVRNIVQQQFCGEYAYVTVCNQCGRESKLLSKFYELELNIQGHK-----QLTDCISEFLKEEKLEGDNRYFCENCQSKQNAT 153
           .457889999*****************************************.....9******************************** PP
   S: 219  kklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctspeekqkekkkYeLiavvvHsG.slssGHYvayvkn.ekgk 305
           +k++l +lP +L l+L+Rf f++++++++k+n+++ f ++Ld++p+++++       + YeL+av++H G s+ sGHY+a+vk+ ++g+
   Q: 154  RKIRLLSLPCTLNLQLMRFVFDRQTGHKKKLNTYIGFSEMLDMEPYVEHKGG----AYVYELSAVLIHRGvSAYSGHYIAHVKDpQSGE 238
           ***********************************************99554....79**************************44555 PP
   S: 306  WllfdDskVtevkeeevleetg.......................staYvlfYk 336
           W++f+D+ +++++ ++ +   +                       ++aY+l+Y+
   Q: 239  WYKFNDEDIEKMEGKKLQLGIEedlaepsksqtrkpkcgkgthcsRNAYMLVYR 292
           ************9999998665999****************************8 PP

ULD/UDP/UBQ/UBQ_Other

   S: 16   k...vnpsdtVaeLKekiekklgippeqqrLiykGkiL.eddktLadyglkdgstihllekks 74
           k   v+   t +eLK +i +++++ p +q+L ++GkiL +d+ tL+ +g+ ++s+i+l  +++
   Q: 818  KallVSANQTLKELKIQIMHAFSVAPFDQNLSIDGKILsDDCATLGTLGVIPESVILLKADEP 880
           344489999************************************************988775 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MMGDGVQEER DYEPQTICEH LQYLFALLQN SNRRYIDPSG FVKALGLDTG QQQDAQEFSK 60
LFMSLLEDTL SKQKNPDVRN IVQQQFCGEY AYVTVCNQCG RESKLLSKFY ELELNIQGHK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGCTCCTTGG TGGCAAGGCC ATGGCAGCGC GGCTGCAGCT GGAGAAGGCT CGCCTGGCGC 60
TGGGCGGAGA CGGTGCGGCC CGAGGAGGTG TCGCAGGAGC ACATCGAGAC CGCCTACCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom
IPR033841--USP48
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS50053--UBIQUITIN_2
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005829--C:cytosol
GO:0005739--C:mitochondrion
GO:0005654--C:nucleoplasm
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000130	Aegilops tauschii	34.06	1.00e-68	254.00
IUUC-Aml-001357	Ailuropoda melanoleuca	97.25	0.00e+00	1755.00
IUUC-Atr-002976	Amborella trichopoda	33.06	7.00e-67	249.00
IUUC-Apl-003773	Anas platyrhynchos	87.38	0.00e+00	1590.00
IUUC-Aca-004466	Anolis carolinensis	80.76	0.00e+00	715.00
IUUC-Aly-006249	Arabidopsis lyrata	29.90	2.00e-58	221.00
IUUC-Ath-006700	Arabidopsis thaliana	31.61	8.00e-68	252.00
IUUC-Ame-011554	Astyanax mexicanus	68.24	0.00e+00	1229.00
IUUC-Bta-012573	Bos taurus	96.05	0.00e+00	1750.00
IUUC-Bdi-014149	Brachypodium distachyon	33.67	2.00e-71	264.00
IUUC-Bol-016289	Brassica oleracea	29.74	2.00e-68	254.00
IUUC-Bra-017494	Brassica rapa	33.73	2.00e-71	264.00
IUUC-Cja-019991	Callithrix jacchus	95.55	0.00e+00	1756.00
IUUC-Cfa-020294	Canis familiaris	97.47	0.00e+00	1793.00
IUUC-Cpo-021706	Cavia porcellus	94.39	0.00e+00	1733.00
IUUC-Cre-022636	Chlamydomonas reinhardtii	33.44	8.00e-38	153.00
IUUC-Csa-023931	Chlorocebus sabaeus	96.81	0.00e+00	1771.00
IUUC-Cho-024566	Choloepus hoffmanni	96.75	3.00e-152	532.00
IUUC-Cin-025307	Ciona intestinalis	57.50	2.00e-49	189.00
IUUC-Csv-026006	Ciona savignyi	37.61	2.00e-125	443.00
IUUC-Cne-027065	Cryptococcus neoformans	27.53	2.00e-53	204.00
IUUC-Dre-027624	Danio rerio	68.47	0.00e+00	1273.00
IUUC-Dno-029633	Dasypus novemcinctus	97.31	0.00e+00	1319.00
IUUC-Dor-030809	Dipodomys ordii	71.47	0.00e+00	931.00
IUUC-Ete-032818	Echinops telfairi	89.39	0.00e+00	776.00
IUUC-Eca-033692	Equus caballus	97.47	0.00e+00	1779.00
IUUC-Eeu-035185	Erinaceus europaeus	74.09	0.00e+00	769.00
IUUC-Fca-035676	Felis catus	96.92	0.00e+00	1784.00
IUUC-Fal-036913	Ficedula albicollis	86.45	0.00e+00	1578.00
IUUC-Gmo-038532	Gadus morhua	64.51	0.00e+00	1184.00
IUUC-Gga-041041	Gallus gallus	86.78	0.00e+00	1576.00
IUUC-Gac-042570	Gasterosteus aculeatus	65.61	0.00e+00	1226.00
IUUC-Gma-044136	Glycine max	30.52	6.00e-78	285.00
IUUC-Ggo-045367	Gorilla gorilla	91.33	0.00e+00	1634.00
IUUC-Hsa-046019	Homo sapiens	96.92	0.00e+00	1774.00
IUUC-Hvu-047303	Hordeum vulgare	35.32	2.00e-53	203.00
IUUC-Itr-048319	Ictidomys tridecemlineatus	94.94	0.00e+00	1757.00
IUUC-Lch-049989	Latimeria chalumnae	75.63	0.00e+00	1412.00
IUUC-Lpe-051612	Leersia perrieri	34.06	4.00e-69	256.00
IUUC-Loc-052756	Lepisosteus oculatus	70.44	0.00e+00	1310.00
IUUC-Laf-054043	Loxodonta africana	95.57	0.00e+00	1773.00
IUUC-Mcc-054986	Macaca mulatta	95.24	0.00e+00	1755.00
IUUC-Meu-056228	Macropus eugenii	76.58	0.00e+00	848.00
IUUC-Mtr-058762	Medicago truncatula	30.12	7.00e-76	279.00
IUUC-Mga-059896	Meleagris gallopavo	85.70	0.00e+00	1549.00
IUUC-Mvi-060269	Microbotryum violaceum	39.83	7.00e-48	186.00
IUUC-Mmr-060887	Microcebus murinus	96.92	0.00e+00	1769.00
IUUC-Mdo-062506	Monodelphis domestica	92.08	0.00e+00	1708.00
IUUC-Mmu-063642	Mus musculus	91.77	0.00e+00	1710.00
IUUC-Mac-064896	Musa acuminata	32.49	5.00e-67	249.00
IUUC-Mpu-066194	Mustela putorius furo	97.69	0.00e+00	1783.00
IUUC-Mlu-067233	Myotis lucifugus	95.53	0.00e+00	1747.00
IUUC-Nle-069052	Nomascus leucogenys	95.66	0.00e+00	1757.00
IUUC-Opr-070890	Ochotona princeps	94.43	0.00e+00	979.00
IUUC-Ont-071450	Oreochromis niloticus	63.12	0.00e+00	1170.00
IUUC-Oan-073252	Ornithorhynchus anatinus	89.57	0.00e+00	1035.00
IUUC-Oba-075563	Oryza barthii	33.66	4.00e-71	263.00
IUUC-Obr-076394	Oryza brachyantha	34.19	1.00e-71	265.00
IUUC-Ogl-077339	Oryza glaberrima	49.07	2.00e-31	129.00
IUUC-Ogu-079007	Oryza glumaepatula	34.98	1.00e-64	241.00
IUUC-Oin-079997	Oryza indica	33.66	2.00e-71	264.00
IUUC-Olo-080364	Oryza longistaminata	33.66	3.00e-71	263.00
IUUC-Ome-081165	Oryza meridionalis	34.97	3.00e-65	243.00
IUUC-Oni-083026	Oryza nivara	33.66	2.00e-71	264.00
IUUC-Opu-083284	Oryza punctata	36.30	9.00e-65	242.00
IUUC-Oru-084797	Oryza rufipogon	33.66	3.00e-71	263.00
IUUC-Osa-086221	Oryza sativa	49.07	2.00e-31	129.00
IUUC-Ola-086568	Oryzias latipes	65.99	0.00e+00	1228.00
IUUC-Oga-088687	Otolemur garnettii	95.01	0.00e+00	1747.00
IUUC-Oar-090345	Ovis aries	96.60	0.00e+00	1759.00
IUUC-Ptr-090734	Pan troglodytes	96.81	0.00e+00	1773.00
IUUC-Pan-091704	Papio anubis	92.76	0.00e+00	1680.00
IUUC-Psi-092937	Pelodiscus sinensis	87.58	0.00e+00	1558.00
IUUC-Ppa-095808	Physcomitrella patens	29.48	4.00e-60	227.00
IUUC-Pab-098129	Pongo abelii	96.92	0.00e+00	1775.00
IUUC-Pop-099738	Populus trichocarpa	26.27	4.00e-65	243.00
IUUC-Pca-100647	Procavia capensis	78.34	2.00e-133	470.00
IUUC-Ppe-102091	Prunus persica	29.41	1.00e-69	258.00
IUUC-Pva-102719	Pteropus vampyrus	96.48	0.00e+00	1756.00
IUUC-Rno-105363	Rattus norvegicus	93.61	0.00e+00	1723.00
IUUC-Sha-107620	Sarcophilus harrisii	88.61	0.00e+00	1658.00
IUUC-Smo-109487	Selaginella moellendorffii	27.49	1.00e-73	271.00
IUUC-Sit-110683	Setaria italica	34.19	1.00e-70	261.00
IUUC-Sly-111377	Solanum lycopersicum	31.14	3.00e-69	256.00
IUUC-Stu-111969	Solanum tuberosum	33.09	5.00e-58	218.00
IUUC-Sar-113099	Sorex araneus	96.21	0.00e+00	1729.00
IUUC-Sbi-113833	Sorghum bicolor	45.57	3.00e-49	188.00
IUUC-Ssc-115279	Sus scrofa	90.73	0.00e+00	1342.00
IUUC-Tgu-117519	Taeniopygia guttata	83.37	0.00e+00	1499.00
IUUC-Tru-117651	Takifugu rubripes	65.30	0.00e+00	1210.00
IUUC-Tsy-119201	Tarsius syrichta	93.06	0.00e+00	1639.00
IUUC-Tni-120840	Tetraodon nigroviridis	67.38	0.00e+00	1231.00
IUUC-Tca-121674	Theobroma cacao	28.88	1.00e-74	275.00
IUUC-Tae-125247	Triticum aestivum	29.02	2.00e-69	258.00
IUUC-Tur-126599	Triticum urartu	34.54	5.00e-68	253.00
IUUC-Tbe-127782	Tupaia belangeri	84.15	0.00e+00	1449.00
IUUC-Ttr-128312	Tursiops truncatus	95.60	0.00e+00	1733.00
IUUC-Vpa-130348	Vicugna pacos	97.03	0.00e+00	1767.00
IUUC-Vvi-131353	Vitis vinifera	30.95	5.00e-72	266.00
IUUC-Xtr-132172	Xenopus tropicalis	70.04	0.00e+00	1187.00
IUUC-Xma-133263	Xiphophorus maculatus	67.32	0.00e+00	1204.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence