iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Psi-092937

Ensembl Protein ID

ENSPSIP00000004785.1

UniProt Accession

K7F9S5; K7F9S5_PELSI

Genbank Protein ID

ENSPSIP00000004785

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGCU01047425

Gene Name

USP48

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000004475.1	ENSPSIT00000004812.1	ENSPSIP00000004785.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.10e-64	218.7	10	314
ULD/UDP/UBQ/UBQ_Other	2.30e-11	43.4	845	903

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 17   QcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqqDaqEflaflldqlee 105
           Q+L+ +p+  + + +   e ++++ ++ +  +++++lq lf+ l++s++++++p+ ++kal+     +++ +qqDaqEf + +++ le+
   Q: 10   QALYLCPSTCSEYVT--GEGIPKD-RDYEPRTICEHLQYLFALLQNSNRRYIDPSGFVKALG-----LDTGQQQDAQEFSKLFMSLLED 90
           778888877666666..5666654.578889******************************9.....78899***************** PP
   S: 106  elkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkkeslqdcLesf 194
           +l                       +++k+   ++++++ F g++   ++c++c+++s+  ++f++l+l+++g++     +l+dc+ +f
   Q: 91   TL-----------------------SKQKNPDVRNIVQKQFCGEYAYVTVCNQCGRESKLISKFYELELNIQGHK-----QLTDCITEF 151
           **.......................457889999*****************************************.....9******** PP
   S: 195  tkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctspeekqkekkkYeLiav 283
            kee+leg+n+y+ce+c++kq+a++k++l +lP +L l+L+Rf f++++++++k+n+++ f + Ld++pf+++++        YeL+av
   Q: 152  LKEEKLEGDNRYFCETCQSKQNATRKIRLLSLPCTLNLQLMRFVFDRQTGHKKKLNTYIGFSELLDMEPFMEQKDG----VSVYELSAV 236
           **************************************************************99*********664....579****** PP
   S: 284  vvHsG.slssGHYvayvknekgk.WllfdDskVtevkeeevleetg.......................staYvlfYk 336
           ++H G s+ sGHY+a+vk+ + + W++f+D+ +++++ ++ +   +                       ++aY+l+Y+
   Q: 237  LIHRGvSAYSGHYIAHVKDPQTGeWYKFNDEDIEKMEGKKLQLGIEedlaepsksqtrkpkcgkgthcsRNAYMLVYR 314
           *******************55555************9999998665999****************************8 PP

ULD/UDP/UBQ/UBQ_Other

   S: 17   vnpsdtVaeLKekiekklgippeqqrLiykGkiL.eddktLadyglkdgstihllekks 74
           v+   t +eLK +i +++++ p +q+L ++GkiL +d  tL+d+g+ ++s+i+l  +++
   Q: 845  VSANQTLKELKIQIMHAFSVAPFDQNLSIDGKILnDDTATLGDLGVIPESVILLKADEP 903
           88899************************************************988775 PP

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

MWFLNLELRQ ALYLCPSTCS EYVTGEGIPK DRDYEPRTIC EHLQYLFALL QNSNRRYIDP 60
SGFVKALGLD TGQQQDAQEF SKLFMSLLED TLSKQKNPDV RNIVQKQFCG EYAYVTVCNQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCGCCTGCCC AGCCGCCCCT CCCCCGCCTC GGGAGGAGAA CCCGGAACCG TCGAGGCATC 60
CCGGCCAAGA GCATGTAGCG CCCTTGAAAC CCTGGCCAAG TCCTGGGCTT CCCGGCATCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom
IPR033841--USP48
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS50053--UBIQUITIN_2
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

SMART

SM00695--DUSP

Gene Ontology

GO:0005829--C:cytosol
GO:0005739--C:mitochondrion
GO:0005654--C:nucleoplasm
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000130	Aegilops tauschii	27.65	7.00e-66	245.00
IUUC-Aml-001357	Ailuropoda melanoleuca	87.23	0.00e+00	1597.00
IUUC-Atr-002976	Amborella trichopoda	33.06	1.00e-65	244.00
IUUC-Apl-003773	Anas platyrhynchos	93.57	0.00e+00	1723.00
IUUC-Aca-004466	Anolis carolinensis	83.11	0.00e+00	776.00
IUUC-Aly-006249	Arabidopsis lyrata	30.83	3.00e-58	220.00
IUUC-Ath-006700	Arabidopsis thaliana	32.21	4.00e-67	249.00
IUUC-Ame-011554	Astyanax mexicanus	66.17	0.00e+00	1209.00
IUUC-Bta-012573	Bos taurus	86.71	0.00e+00	1595.00
IUUC-Bdi-014149	Brachypodium distachyon	32.86	2.00e-69	257.00
IUUC-Bol-016289	Brassica oleracea	34.06	3.00e-68	253.00
IUUC-Bra-017494	Brassica rapa	34.46	2.00e-71	264.00
IUUC-Cja-019991	Callithrix jacchus	86.02	0.00e+00	1597.00
IUUC-Cfa-020294	Canis familiaris	87.66	0.00e+00	1632.00
IUUC-Cpo-021706	Cavia porcellus	85.37	0.00e+00	1591.00
IUUC-Cre-022636	Chlamydomonas reinhardtii	33.23	5.00e-37	150.00
IUUC-Csa-023931	Chlorocebus sabaeus	87.23	0.00e+00	1613.00
IUUC-Cho-024566	Choloepus hoffmanni	86.59	2.00e-128	453.00
IUUC-Cin-025307	Ciona intestinalis	51.78	1.00e-50	192.00
IUUC-Csv-026006	Ciona savignyi	35.85	7.00e-125	441.00
IUUC-Cne-027065	Cryptococcus neoformans	27.99	2.00e-57	217.00
IUUC-Dre-027624	Danio rerio	66.81	0.00e+00	1252.00
IUUC-Dno-029633	Dasypus novemcinctus	87.91	0.00e+00	1192.00
IUUC-Dor-030809	Dipodomys ordii	65.75	0.00e+00	887.00
IUUC-Ete-032818	Echinops telfairi	82.66	0.00e+00	748.00
IUUC-Eca-033692	Equus caballus	87.55	0.00e+00	1617.00
IUUC-Eeu-035185	Erinaceus europaeus	65.67	0.00e+00	661.00
IUUC-Fca-035676	Felis catus	87.01	0.00e+00	1621.00
IUUC-Fal-036913	Ficedula albicollis	91.69	0.00e+00	1688.00
IUUC-Gmo-038532	Gadus morhua	62.04	0.00e+00	1156.00
IUUC-Gga-041041	Gallus gallus	92.46	0.00e+00	1694.00
IUUC-Gac-042570	Gasterosteus aculeatus	63.74	0.00e+00	1203.00
IUUC-Gma-044136	Glycine max	30.34	6.00e-79	289.00
IUUC-Ggo-045367	Gorilla gorilla	82.48	0.00e+00	1488.00
IUUC-Hsa-046019	Homo sapiens	87.12	0.00e+00	1610.00
IUUC-Hvu-047303	Hordeum vulgare	34.77	6.00e-51	194.00
IUUC-Itr-048319	Ictidomys tridecemlineatus	85.03	0.00e+00	1591.00
IUUC-Lch-049989	Latimeria chalumnae	74.95	0.00e+00	1401.00
IUUC-Lpe-051612	Leersia perrieri	33.80	4.00e-67	249.00
IUUC-Loc-052756	Lepisosteus oculatus	68.58	0.00e+00	1296.00
IUUC-Laf-054043	Loxodonta africana	85.76	0.00e+00	1600.00
IUUC-Mcc-054986	Macaca mulatta	85.82	0.00e+00	1595.00
IUUC-Meu-056228	Macropus eugenii	73.68	0.00e+00	781.00
IUUC-Mtr-058610	Medicago truncatula	29.56	2.00e-68	254.00
IUUC-Mga-059896	Meleagris gallopavo	92.12	0.00e+00	1670.00
IUUC-Mvi-060269	Microbotryum violaceum	36.14	6.00e-49	189.00
IUUC-Mmr-060887	Microcebus murinus	87.12	0.00e+00	1608.00
IUUC-Mdo-062506	Monodelphis domestica	87.99	0.00e+00	1633.00
IUUC-Mmu-063642	Mus musculus	82.98	0.00e+00	1556.00
IUUC-Mac-064896	Musa acuminata	32.43	6.00e-67	249.00
IUUC-Mpu-066194	Mustela putorius furo	87.34	0.00e+00	1606.00
IUUC-Mlu-067233	Myotis lucifugus	86.70	0.00e+00	1600.00
IUUC-Nle-069052	Nomascus leucogenys	85.88	0.00e+00	1596.00
IUUC-Opr-070890	Ochotona princeps	85.90	0.00e+00	927.00
IUUC-Ont-071450	Oreochromis niloticus	62.55	0.00e+00	1154.00
IUUC-Oan-073252	Ornithorhynchus anatinus	87.02	0.00e+00	974.00
IUUC-Ocu-073796	Oryctolagus cuniculus	87.58	0.00e+00	1563.00
IUUC-Oba-075563	Oryza barthii	29.93	1.00e-69	258.00
IUUC-Obr-076394	Oryza brachyantha	33.40	6.00e-69	255.00
IUUC-Ogl-077339	Oryza glaberrima	49.07	2.00e-31	129.00
IUUC-Ogu-079007	Oryza glumaepatula	36.16	2.00e-63	237.00
IUUC-Oin-079997	Oryza indica	29.93	7.00e-70	258.00
IUUC-Olo-080364	Oryza longistaminata	29.93	8.00e-70	258.00
IUUC-Ome-081165	Oryza meridionalis	34.52	1.00e-63	238.00
IUUC-Oni-083026	Oryza nivara	29.93	8.00e-70	258.00
IUUC-Opu-083284	Oryza punctata	36.82	5.00e-64	239.00
IUUC-Oru-084797	Oryza rufipogon	29.93	1.00e-69	258.00
IUUC-Osa-086221	Oryza sativa	49.07	2.00e-31	129.00
IUUC-Ola-086568	Oryzias latipes	64.40	0.00e+00	1204.00
IUUC-Oga-088687	Otolemur garnettii	85.68	0.00e+00	1591.00
IUUC-Oar-090345	Ovis aries	87.16	0.00e+00	1602.00
IUUC-Ptr-090734	Pan troglodytes	87.23	0.00e+00	1612.00
IUUC-Pan-091704	Papio anubis	83.46	0.00e+00	1531.00
IUUC-Ppa-095808	Physcomitrella patens	28.69	1.00e-57	218.00
IUUC-Pab-098129	Pongo abelii	87.23	0.00e+00	1612.00
IUUC-Pop-099494	Populus trichocarpa	33.00	2.00e-66	247.00
IUUC-Pca-100647	Procavia capensis	91.56	1.00e-124	441.00
IUUC-Ppe-102091	Prunus persica	30.29	4.00e-68	253.00
IUUC-Pva-102719	Pteropus vampyrus	86.90	0.00e+00	1598.00
IUUC-Rno-105363	Rattus norvegicus	85.15	0.00e+00	1583.00
IUUC-Sha-107620	Sarcophilus harrisii	85.85	0.00e+00	1596.00
IUUC-Smo-109487	Selaginella moellendorffii	27.36	8.00e-72	265.00
IUUC-Sit-110683	Setaria italica	30.12	4.00e-72	266.00
IUUC-Sly-111377	Solanum lycopersicum	32.56	2.00e-66	247.00
IUUC-Stu-111969	Solanum tuberosum	33.66	3.00e-57	216.00
IUUC-Sar-113099	Sorex araneus	87.54	0.00e+00	1551.00
IUUC-Sbi-113833	Sorghum bicolor	45.57	1.00e-48	186.00
IUUC-Ssc-115279	Sus scrofa	79.86	0.00e+00	1152.00
IUUC-Tgu-117519	Taeniopygia guttata	88.54	0.00e+00	1608.00
IUUC-Tru-117651	Takifugu rubripes	65.06	0.00e+00	1202.00
IUUC-Tsy-119201	Tarsius syrichta	84.17	0.00e+00	1493.00
IUUC-Tni-120840	Tetraodon nigroviridis	64.73	0.00e+00	1212.00
IUUC-Tca-121674	Theobroma cacao	27.58	5.00e-72	266.00
IUUC-Tae-125247	Triticum aestivum	25.52	1.00e-67	251.00
IUUC-Tur-126599	Triticum urartu	29.44	2.00e-65	243.00
IUUC-Tbe-127782	Tupaia belangeri	76.75	0.00e+00	1349.00
IUUC-Ttr-128312	Tursiops truncatus	85.81	0.00e+00	1574.00
IUUC-Vpa-130348	Vicugna pacos	86.90	0.00e+00	1600.00
IUUC-Vvi-131353	Vitis vinifera	33.72	7.00e-72	265.00
IUUC-Xtr-132172	Xenopus tropicalis	69.20	0.00e+00	1182.00
IUUC-Xma-133263	Xiphophorus maculatus	64.84	0.00e+00	1168.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence