iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ang-009654

Ensembl Protein ID

CAK44202

UniProt Accession

A2QD53; A2QD53_ASPNC

Genbank Protein ID

CAK44202.1

Protein Name

Coatomer subunit beta'

Genbank Nucleotide ID

AM270012

Gene Name

An02g05870

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
An02g05870	CAK44202	CAK44202

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.80e-30	102.6	96	129
UBD/Beta-Prp	6.40e-65	218.8	13	295

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtg 33
           H d ++++a  ++ ++++++sdD tik+WD+ +g
   Q: 96   HPDYIRSIAVhPTqPFVLTASDDMTIKLWDWERG 129
           99********9888****************8765 PP

UBD/Beta-Prp

   S: 10   ksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklv 110
           +++++ ++f+p +++++t+ ++g + +w+++t++ +++++  + +v+a +f+ +++++v gs+D  ++v++++t++ + ++++h d+++s++++p++ +++
   Q: 13   SERVKGIDFHPTEPWILTTLYSGHVYIWSYETQSIIKTFELTDVPVRAGRFIARKNWIVCGSDDFQLRVYNYNTSEKIASFEAHPDYIRSIAVHPTQPFVL 113
           678999*********************************************************************************************** PP
   S: 111  sGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsng..kelvsgsldgtvklwd 208
           ++s+d ti++wd+e g++  ++ +gh++ v++++++p++ n ++s++lDrtv++W+l +     tl+   t+ v+++++ ++   ++l++ s+d+tvk+wd
   Q: 114  TASDDMTIKLWDWERGWKCVQVYEGHSHYVMGLAINPKDtNTFASACLDRTVKIWSLGSPHANFTLEAHETKGVNHVDYYPQAdkPYLLTTSDDRTVKIWD 214
           ****************98888***********************************************99********8887777**************** PP
   S: 209  lqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsfgdnvlvlgsedskvni 291
           + t+  + tl+ght+nv+    +p+   ++sgs+Dg+i++W   +  l ++l++  ++ +++a+ + g++ + + ++d+ + +
   Q: 215  YTTKALIATLEGHTSNVSFACYHPELPVIISGSEDGTIKLWHANTYRLEQSLSYGLERAWCIAY-QRGRQGV-AMGFDDGAVV 295
           ***************************************************************9.4444444.4444444444 PP

Organism

Aspergillus niger

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

Protein Sequence
(Fasta)

MKLDVKRQLF ARSERVKGID FHPTEPWILT TLYSGHVYIW SYETQSIIKT FELTDVPVRA 60
GRFIARKNWI VCGSDDFQLR VYNYNTSEKI ASFEAHPDYI RSIAVHPTQP FVLTASDDMT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAAATTGG ATGTCAAGGT ACGGGTTATA ATGCTGAGTC TAAAGCCCTT AGTTCAACAA 60
GAGGCTGTGA CGTGCGAAGG ATATATTTTC AGGAAACAAT TATACGGATG CTGACTGTTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0968--Cytoplasmic vesicle
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR006692--Coatomer_WD-assoc_reg
IPR016453--COPB2
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030663--C:COPI-coated vesicle membrane
GO:0000139--C:Golgi membrane
GO:0030117--C:membrane coat
GO:0005198--F:structural molecule activity
GO:0006886--P:intracellular protein transport
GO:0016192--P:vesicle-mediated transport

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000654	Aegilops tauschii	47.08	0.00e+00	674.00
IUUC-Aml-002154	Ailuropoda melanoleuca	56.32	0.00e+00	863.00
IUUC-Atr-003090	Amborella trichopoda	56.82	0.00e+00	814.00
IUUC-Apl-003976	Anas platyrhynchos	56.32	0.00e+00	862.00
IUUC-Aca-004301	Anolis carolinensis	56.47	0.00e+00	867.00
IUUC-Aly-006508	Arabidopsis lyrata	55.91	0.00e+00	795.00
IUUC-Ath-007635	Arabidopsis thaliana	55.91	0.00e+00	797.00
IUUC-Ago-007914	Ashbya gossypii	53.61	0.00e+00	761.00
IUUC-Acl-008237	Aspergillus clavatus	96.95	0.00e+00	1336.00
IUUC-Afl-008535	Aspergillus flavus	95.66	0.00e+00	1263.00
IUUC-Afu-008845	Aspergillus fumigatus	96.49	0.00e+00	1298.00
IUUC-Ani-009135	Aspergillus nidulans	94.73	0.00e+00	1269.00
IUUC-Aor-009939	Aspergillus oryzae	95.73	0.00e+00	1332.00
IUUC-Ate-010355	Aspergillus terreus	97.05	0.00e+00	1283.00
IUUC-Ame-010922	Astyanax mexicanus	51.36	0.00e+00	736.00
IUUC-Bgr-012249	Blumeria graminis	82.90	0.00e+00	1130.00
IUUC-Bta-013579	Bos taurus	55.90	0.00e+00	819.00
IUUC-Bci-013866	Botrytis cinerea	86.28	0.00e+00	1180.00
IUUC-Bdi-015046	Brachypodium distachyon	57.21	0.00e+00	807.00
IUUC-Bol-016012	Brassica oleracea	56.21	0.00e+00	808.00
IUUC-Bra-017758	Brassica rapa	55.45	0.00e+00	803.00
IUUC-Cel-018387	Caenorhabditis elegans	54.26	0.00e+00	783.00
IUUC-Cja-019145	Callithrix jacchus	56.32	0.00e+00	863.00
IUUC-Cfa-020564	Canis familiaris	56.32	0.00e+00	863.00
IUUC-Cpo-022201	Cavia porcellus	56.32	0.00e+00	864.00
IUUC-Cre-022938	Chlamydomonas reinhardtii	55.54	0.00e+00	800.00
IUUC-Csa-023383	Chlorocebus sabaeus	59.05	0.00e+00	747.00
IUUC-Cho-024454	Choloepus hoffmanni	56.98	0.00e+00	792.00
IUUC-Cin-025681	Ciona intestinalis	56.15	0.00e+00	800.00
IUUC-Csv-026012	Ciona savignyi	56.90	0.00e+00	810.00
IUUC-Cgl-026649	Colletotrichum gloeosporioides	78.02	0.00e+00	1032.00
IUUC-Cne-026986	Cryptococcus neoformans	60.61	0.00e+00	872.00
IUUC-Cme-027219	Cyanidioschyzon merolae	47.65	0.00e+00	684.00
IUUC-Dre-027846	Danio rerio	55.60	0.00e+00	858.00
IUUC-Dor-030462	Dipodomys ordii	54.10	0.00e+00	770.00
IUUC-Dse-031268	Dothistroma septosporum	83.64	0.00e+00	1140.00
IUUC-Dme-031791	Drosophila melanogaster	55.96	0.00e+00	823.00
IUUC-Ete-033166	Echinops telfairi	52.86	4.00e-180	623.00
IUUC-Eca-034180	Equus caballus	54.66	0.00e+00	820.00
IUUC-Eeu-035086	Erinaceus europaeus	52.21	4.00e-79	288.00
IUUC-Fca-036265	Felis catus	56.32	0.00e+00	863.00
IUUC-Fal-037202	Ficedula albicollis	55.75	0.00e+00	819.00
IUUC-Fox-037711	Fusarium oxysporum	84.67	0.00e+00	1122.00
IUUC-Fso-038268	Fusarium solani	83.67	0.00e+00	1112.00
IUUC-Gmo-039046	Gadus morhua	55.17	0.00e+00	848.00
IUUC-Ggr-039863	Gaeumannomyces graminis	84.76	0.00e+00	1146.00
IUUC-Gga-041112	Gallus gallus	56.32	0.00e+00	863.00
IUUC-Gac-041733	Gasterosteus aculeatus	56.03	0.00e+00	851.00
IUUC-Gma-044333	Glycine max	56.46	0.00e+00	823.00
IUUC-Ggo-044984	Gorilla gorilla	56.32	0.00e+00	863.00
IUUC-Hsa-046698	Homo sapiens	56.18	0.00e+00	862.00
IUUC-Hvu-047669	Hordeum vulgare	61.30	5.00e-142	495.00
IUUC-Itr-048212	Ictidomys tridecemlineatus	56.32	0.00e+00	862.00
IUUC-Kpa-049265	Komagataella pastoris	59.27	0.00e+00	863.00
IUUC-Lch-050473	Latimeria chalumnae	55.75	0.00e+00	861.00
IUUC-Lpe-051579	Leersia perrieri	56.43	0.00e+00	813.00
IUUC-Loc-052675	Lepisosteus oculatus	55.46	0.00e+00	858.00
IUUC-Lma-053218	Leptosphaeria maculans	78.13	0.00e+00	1044.00
IUUC-Laf-053757	Loxodonta africana	56.02	0.00e+00	855.00
IUUC-Mcc-054859	Macaca mulatta	56.32	0.00e+00	863.00
IUUC-Meu-056174	Macropus eugenii	45.81	9.00e-59	220.00
IUUC-Mor-057264	Magnaporthe oryzae	84.91	0.00e+00	1144.00
IUUC-Mpo-057538	Magnaporthe poae	84.76	0.00e+00	1148.00
IUUC-Mtr-058310	Medicago truncatula	56.97	0.00e+00	818.00
IUUC-Mla-058937	Melampsora laricipopulina	60.49	0.00e+00	840.00
IUUC-Mga-059875	Meleagris gallopavo	56.02	0.00e+00	858.00
IUUC-Mvi-060240	Microbotryum violaceum	61.11	0.00e+00	874.00
IUUC-Mmr-061261	Microcebus murinus	56.32	0.00e+00	863.00
IUUC-Mdo-062076	Monodelphis domestica	56.61	0.00e+00	868.00
IUUC-Mmu-063324	Mus musculus	58.97	0.00e+00	862.00
IUUC-Mac-064636	Musa acuminata	55.13	0.00e+00	811.00
IUUC-Mpu-065961	Mustela putorius furo	56.32	0.00e+00	863.00
IUUC-Mlu-067059	Myotis lucifugus	58.97	0.00e+00	861.00
IUUC-Nfi-068277	Neosartorya fischeri	96.78	0.00e+00	1292.00
IUUC-Ncr-068659	Neurospora crassa	79.64	0.00e+00	1102.00
IUUC-Nle-069034	Nomascus leucogenys	56.32	0.00e+00	863.00
IUUC-Opr-070334	Ochotona princeps	56.18	0.00e+00	850.00
IUUC-Ont-071563	Oreochromis niloticus	55.75	0.00e+00	854.00
IUUC-Oan-073416	Ornithorhynchus anatinus	56.20	0.00e+00	823.00
IUUC-Ocu-074522	Oryctolagus cuniculus	56.18	0.00e+00	860.00
IUUC-Oba-075751	Oryza barthii	57.01	0.00e+00	802.00
IUUC-Obr-076201	Oryza brachyantha	56.02	0.00e+00	810.00
IUUC-Ogl-077450	Oryza glaberrima	54.38	0.00e+00	806.00
IUUC-Ogu-078994	Oryza glumaepatula	53.64	0.00e+00	783.00
IUUC-Oin-079856	Oryza indica	57.10	0.00e+00	801.00
IUUC-Olo-080731	Oryza longistaminata	54.49	0.00e+00	771.00
IUUC-Ome-081554	Oryza meridionalis	52.80	0.00e+00	734.00
IUUC-Oni-082324	Oryza nivara	53.64	0.00e+00	783.00
IUUC-Opu-083400	Oryza punctata	54.37	0.00e+00	783.00
IUUC-Oru-085196	Oryza rufipogon	57.01	0.00e+00	803.00
IUUC-Osa-086026	Oryza sativa	54.68	0.00e+00	810.00
IUUC-Ola-087245	Oryzias latipes	55.75	0.00e+00	854.00
IUUC-Olu-087655	Ostreococcus lucimarinus	57.21	0.00e+00	808.00
IUUC-Oga-088163	Otolemur garnettii	53.87	0.00e+00	818.00
IUUC-Oar-089842	Ovis aries	56.32	0.00e+00	863.00
IUUC-Ptr-090501	Pan troglodytes	56.32	0.00e+00	863.00
IUUC-Pan-092011	Papio anubis	56.32	0.00e+00	863.00
IUUC-Psi-093308	Pelodiscus sinensis	56.18	0.00e+00	861.00
IUUC-Pma-094695	Petromyzon marinus	57.14	0.00e+00	803.00
IUUC-Pno-094785	Phaeosphaeria nodorum	77.85	3.00e-138	483.00
IUUC-Ppa-095412	Physcomitrella patens	56.45	0.00e+00	818.00
IUUC-Pfo-096587	Poecilia formosa	55.89	0.00e+00	858.00
IUUC-Pab-097926	Pongo abelii	57.27	0.00e+00	808.00
IUUC-Pop-099634	Populus trichocarpa	56.90	0.00e+00	817.00
IUUC-Pca-100965	Procavia capensis	55.89	0.00e+00	843.00
IUUC-Ppe-101470	Prunus persica	57.42	0.00e+00	822.00
IUUC-Pva-102451	Pteropus vampyrus	53.65	0.00e+00	758.00
IUUC-Pgr-103590	Puccinia graminis	62.04	0.00e+00	881.00
IUUC-Ptt-103868	Puccinia triticina	61.57	0.00e+00	877.00
IUUC-Pte-104274	Pyrenophora teres	80.58	0.00e+00	1089.00
IUUC-Pyt-104794	Pyrenophora triticirepentis	79.55	0.00e+00	1024.00
IUUC-Rno-105979	Rattus norvegicus	48.21	0.00e+00	703.00
IUUC-Sce-106269	Saccharomyces cerevisiae	54.83	0.00e+00	783.00
IUUC-Sha-106905	Sarcophilus harrisii	56.47	0.00e+00	865.00
IUUC-Sja-107838	Schizosaccharomyces japonicus	55.18	0.00e+00	782.00
IUUC-Spo-108299	Schizosaccharomyces pombe	54.71	0.00e+00	812.00
IUUC-Smo-108695	Selaginella moellendorffii	54.40	0.00e+00	810.00
IUUC-Sit-110692	Setaria italica	57.88	0.00e+00	815.00
IUUC-Sly-111775	Solanum lycopersicum	55.86	0.00e+00	825.00
IUUC-Stu-112906	Solanum tuberosum	55.75	0.00e+00	731.00
IUUC-Sar-113472	Sorex araneus	53.18	0.00e+00	692.00
IUUC-Sbi-113886	Sorghum bicolor	56.76	0.00e+00	827.00
IUUC-Sre-115040	Sporisorium reilianum	61.34	0.00e+00	863.00
IUUC-Ssc-115593	Sus scrofa	56.18	0.00e+00	861.00
IUUC-Tgu-117239	Taeniopygia guttata	56.18	0.00e+00	862.00
IUUC-Tru-118025	Takifugu rubripes	55.67	0.00e+00	851.00
IUUC-Tsy-118824	Tarsius syrichta	52.54	0.00e+00	706.00
IUUC-Tni-120142	Tetraodon nigroviridis	55.75	0.00e+00	849.00
IUUC-Tca-121613	Theobroma cacao	57.58	0.00e+00	823.00
IUUC-Tre-122072	Trichoderma reesei	82.77	0.00e+00	1135.00
IUUC-Tvi-122546	Trichoderma virens	82.97	0.00e+00	1126.00
IUUC-Tae-125488	Triticum aestivum	55.13	0.00e+00	812.00
IUUC-Tur-126283	Triticum urartu	47.52	0.00e+00	674.00
IUUC-Tme-127041	Tuber melanosporum	80.18	0.00e+00	1144.00
IUUC-Tbe-127770	Tupaia belangeri	55.17	0.00e+00	793.00
IUUC-Ttr-129294	Tursiops truncatus	56.18	0.00e+00	860.00
IUUC-Uma-129351	Ustilago maydis	60.27	0.00e+00	873.00
IUUC-Vda-129716	Verticillium dahliae	84.45	0.00e+00	1169.00
IUUC-Vpa-130037	Vicugna pacos	44.64	1.00e-78	286.00
IUUC-Vvi-131689	Vitis vinifera	57.58	0.00e+00	827.00
IUUC-Xtr-132633	Xenopus tropicalis	55.75	0.00e+00	858.00
IUUC-Xma-133347	Xiphophorus maculatus	55.75	0.00e+00	855.00
IUUC-Yli-134455	Yarrowia lipolytica	60.62	0.00e+00	853.00
IUUC-Zma-135867	Zea mays	56.76	0.00e+00	830.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence