iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ggo-044984

UUCD1 version

UUC-GoG-00229

Ensembl Protein ID

ENSGGOP00000005665.2

UniProt Accession

G3QSM3; G3QSM3_GORGO

Protein Name

Coatomer subunit beta'

Gene Name

COPB2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000005780.2	ENSGGOT00000005813.2	ENSGGOP00000005665.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.50e-33	112.6	183	224
UBD/Beta-Prp	4.40e-72	243.2	13	292

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sd.tllvsGsdDgtikvWDlrtgvllks 38
           gH+ +v+c+++    d ++l+sG+dD  +k+WD+   +++++
   Q: 183  GHEKGVNCIDYysgGDkPYLISGADDRLVKIWDYQNKTCVQT 224
           8*********9999778****************999988875 PP

UBD/Beta-Prp

   S: 8    hhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkgheds 96
           ++++++++v+ +p +++++++ ++g++ vw+ +t++l+++++ ++ +v+a kf  ++++ vtg++D+ i+v++++t + vh +++h+d+
   Q: 13   ARSDRVKSVDLHPTEPWMLASLYNGSVCVWNHETQTLVKTFEVCDLPVRAAKFVARKNWVVTGADDMQIRVFNYNTLERVHMFEAHSDY 101
           67899************************************************************************************ PP
   S: 97   vlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsvy 184
           +++++++p++ ++++ s+d  i++wd+++++  +++++gh++ v+ +v++p++ n ++s+slDrt+++W+l + +   tl+g h++ v+
   Q: 102  IRCIAVHPTQPFILTSSDDMLIKLWDWDKKWSCSQVFEGHTHYVMQIVINPKDnNQFASASLDRTIKVWQLGSSSPNFTLEG-HEKGVN 189
           *******************************9999**********************************************9.****** PP
   S: 185  slsfdsng..kelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisva 271
           ++++ s g  ++l+sg++d+ vk+wd+q+++cv+tl+gh +nv++  f+p+  ++++gs+Dg++riW + +  l +tl++  ++v++va
   Q: 190  CIDYYSGGdkPYLISGADDRLVKIWDYQNKTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIWHSSTYRLESTLNYGMERVWCVA 278
           ***8887777******************************************************************************* PP
   S: 272  vlsfgdnvlvlgse 285
            l+ ++nv +  +e
   Q: 279  SLRGSNNVALGYDE 292
           *9999998854444 PP

Organism

Gorilla gorilla

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

Protein Sequence
(Fasta)

MPLRLDIKRK LTARSDRVKS VDLHPTEPWM LASLYNGSVC VWNHETQTLV KTFEVCDLPV 60
RAAKFVARKN WVVTGADDMQ IRVFNYNTLE RVHMFEAHSD YIRCIAVHPT QPFILTSSDD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GACTATCGCG AGAATCGGCT CCCGGAAGTT CCACGTCAGT CAGTCTGACG GTCAGTGGAC 60
CGGTGGGTTT ATCTCAAGGC CTGAGTAGCC GGTAACAAAC GAGGGTTCCC GGGATTGGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0968--Cytoplasmic vesicle
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR006692--Coatomer_WD-assoc_reg
IPR016453--COPB2
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0000139--C:Golgi membrane
GO:0005198--F:structural molecule activity
GO:0006891--P:intra-Golgi vesicle-mediated transport
GO:0006886--P:intracellular protein transport
GO:1901998--P:toxin transport

KEGG

ggo:101153568

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000654	Aegilops tauschii	52.81	0.00e+00	940.00
IUUC-Aml-002154	Ailuropoda melanoleuca	98.34	0.00e+00	1825.00
IUUC-Atr-003090	Amborella trichopoda	58.66	0.00e+00	1076.00
IUUC-Apl-003976	Anas platyrhynchos	94.39	0.00e+00	1726.00
IUUC-Aca-004301	Anolis carolinensis	94.69	0.00e+00	1718.00
IUUC-Aly-006508	Arabidopsis lyrata	60.24	0.00e+00	1093.00
IUUC-Ath-007630	Arabidopsis thaliana	61.82	0.00e+00	1103.00
IUUC-Ago-007914	Ashbya gossypii	46.07	0.00e+00	756.00
IUUC-Acl-008237	Aspergillus clavatus	56.63	0.00e+00	969.00
IUUC-Afl-008535	Aspergillus flavus	56.09	0.00e+00	916.00
IUUC-Afu-008845	Aspergillus fumigatus	54.92	0.00e+00	946.00
IUUC-Ani-009135	Aspergillus nidulans	56.08	0.00e+00	920.00
IUUC-Ang-009654	Aspergillus niger	56.32	0.00e+00	862.00
IUUC-Aor-009939	Aspergillus oryzae	54.89	0.00e+00	973.00
IUUC-Ate-010355	Aspergillus terreus	54.33	0.00e+00	924.00
IUUC-Ame-010922	Astyanax mexicanus	84.45	0.00e+00	1491.00
IUUC-Bgr-012249	Blumeria graminis	53.49	0.00e+00	934.00
IUUC-Bta-013579	Bos taurus	98.88	0.00e+00	1483.00
IUUC-Bci-013866	Botrytis cinerea	56.03	0.00e+00	934.00
IUUC-Bdi-015046	Brachypodium distachyon	60.97	0.00e+00	1105.00
IUUC-Bol-016271	Brassica oleracea	60.47	0.00e+00	1110.00
IUUC-Bra-017758	Brassica rapa	60.43	0.00e+00	1108.00
IUUC-Cel-018387	Caenorhabditis elegans	65.33	0.00e+00	1180.00
IUUC-Cja-019145	Callithrix jacchus	99.34	0.00e+00	1842.00
IUUC-Cfa-020564	Canis familiaris	98.90	0.00e+00	1830.00
IUUC-Cpo-022201	Cavia porcellus	97.02	0.00e+00	1808.00
IUUC-Cre-022938	Chlamydomonas reinhardtii	58.55	0.00e+00	987.00
IUUC-Csa-023383	Chlorocebus sabaeus	98.41	0.00e+00	1182.00
IUUC-Cho-024454	Choloepus hoffmanni	92.38	0.00e+00	1409.00
IUUC-Cin-025681	Ciona intestinalis	75.81	0.00e+00	1362.00
IUUC-Csv-026012	Ciona savignyi	76.78	0.00e+00	1334.00
IUUC-Cgl-026649	Colletotrichum gloeosporioides	52.34	0.00e+00	849.00
IUUC-Cne-026986	Cryptococcus neoformans	51.81	0.00e+00	919.00
IUUC-Cme-027219	Cyanidioschyzon merolae	48.45	0.00e+00	850.00
IUUC-Dre-027846	Danio rerio	93.25	0.00e+00	1669.00
IUUC-Dor-030462	Dipodomys ordii	92.93	0.00e+00	1274.00
IUUC-Dse-031268	Dothistroma septosporum	54.91	0.00e+00	959.00
IUUC-Dme-031791	Drosophila melanogaster	70.16	0.00e+00	1271.00
IUUC-Ete-033166	Echinops telfairi	88.71	0.00e+00	1018.00
IUUC-Eca-034180	Equus caballus	96.23	0.00e+00	1754.00
IUUC-Eeu-035086	Erinaceus europaeus	87.80	0.00e+00	891.00
IUUC-Fca-036265	Felis catus	98.23	0.00e+00	1818.00
IUUC-Fal-037202	Ficedula albicollis	95.20	0.00e+00	1665.00
IUUC-Fox-037711	Fusarium oxysporum	56.83	0.00e+00	894.00
IUUC-Fso-038268	Fusarium solani	56.29	0.00e+00	891.00
IUUC-Gmo-039046	Gadus morhua	92.54	0.00e+00	1649.00
IUUC-Ggr-039863	Gaeumannomyces graminis	55.54	0.00e+00	910.00
IUUC-Gga-041112	Gallus gallus	94.39	0.00e+00	1728.00
IUUC-Gac-041733	Gasterosteus aculeatus	92.66	0.00e+00	1611.00
IUUC-Gma-042910	Glycine max	62.35	0.00e+00	1116.00
IUUC-Hsa-046698	Homo sapiens	99.67	0.00e+00	1848.00
IUUC-Hvu-047669	Hordeum vulgare	70.90	9.00e-169	585.00
IUUC-Itr-048212	Ictidomys tridecemlineatus	96.24	0.00e+00	1770.00
IUUC-Kpa-049265	Komagataella pastoris	49.32	0.00e+00	863.00
IUUC-Lch-050473	Latimeria chalumnae	90.53	0.00e+00	1707.00
IUUC-Lpe-051579	Leersia perrieri	60.93	0.00e+00	1097.00
IUUC-Loc-052675	Lepisosteus oculatus	94.14	0.00e+00	1694.00
IUUC-Lma-053218	Leptosphaeria maculans	54.78	0.00e+00	931.00
IUUC-Laf-053757	Loxodonta africana	98.35	0.00e+00	1817.00
IUUC-Mcc-054859	Macaca mulatta	99.45	0.00e+00	1844.00
IUUC-Meu-056174	Macropus eugenii	95.56	0.00e+00	751.00
IUUC-Mor-057264	Magnaporthe oryzae	56.06	0.00e+00	896.00
IUUC-Mpo-057538	Magnaporthe poae	55.79	0.00e+00	923.00
IUUC-Mtr-058310	Medicago truncatula	62.59	0.00e+00	1126.00
IUUC-Mla-058937	Melampsora laricipopulina	53.44	0.00e+00	916.00
IUUC-Mga-059875	Meleagris gallopavo	94.18	0.00e+00	1723.00
IUUC-Mvi-060240	Microbotryum violaceum	51.68	0.00e+00	917.00
IUUC-Mmr-061261	Microcebus murinus	98.79	0.00e+00	1832.00
IUUC-Mdo-062076	Monodelphis domestica	96.11	0.00e+00	1754.00
IUUC-Mmu-063324	Mus musculus	98.12	0.00e+00	1813.00
IUUC-Mac-064636	Musa acuminata	59.95	0.00e+00	1083.00
IUUC-Mpu-065961	Mustela putorius furo	98.79	0.00e+00	1821.00
IUUC-Mlu-067059	Myotis lucifugus	98.28	0.00e+00	1749.00
IUUC-Nfi-068277	Neosartorya fischeri	54.63	0.00e+00	936.00
IUUC-Ncr-068659	Neurospora crassa	52.83	0.00e+00	914.00
IUUC-Nle-069034	Nomascus leucogenys	99.45	0.00e+00	1843.00
IUUC-Opr-070334	Ochotona princeps	98.64	0.00e+00	1521.00
IUUC-Ont-071563	Oreochromis niloticus	93.37	0.00e+00	1667.00
IUUC-Oan-073416	Ornithorhynchus anatinus	97.57	0.00e+00	1655.00
IUUC-Ocu-074522	Oryctolagus cuniculus	98.34	0.00e+00	1825.00
IUUC-Oba-075760	Oryza barthii	60.05	0.00e+00	1076.00
IUUC-Obr-076163	Oryza brachyantha	62.00	0.00e+00	1098.00
IUUC-Ogl-077450	Oryza glaberrima	61.26	0.00e+00	1103.00
IUUC-Ogu-078994	Oryza glumaepatula	60.05	0.00e+00	1075.00
IUUC-Oin-079856	Oryza indica	57.68	0.00e+00	1078.00
IUUC-Olo-080731	Oryza longistaminata	59.35	0.00e+00	1060.00
IUUC-Ome-081554	Oryza meridionalis	57.49	0.00e+00	1000.00
IUUC-Oni-082324	Oryza nivara	60.05	0.00e+00	1076.00
IUUC-Opu-083400	Oryza punctata	56.17	0.00e+00	1066.00
IUUC-Oru-084829	Oryza rufipogon	60.05	0.00e+00	1076.00
IUUC-Osa-086026	Oryza sativa	61.26	0.00e+00	1107.00
IUUC-Ola-087245	Oryzias latipes	87.82	0.00e+00	1671.00
IUUC-Olu-087655	Ostreococcus lucimarinus	59.98	0.00e+00	1059.00
IUUC-Oga-088163	Otolemur garnettii	95.37	0.00e+00	1749.00
IUUC-Oar-089842	Ovis aries	98.63	0.00e+00	1811.00
IUUC-Ptr-090501	Pan troglodytes	99.56	0.00e+00	1846.00
IUUC-Pan-092011	Papio anubis	99.34	0.00e+00	1842.00
IUUC-Psi-093308	Pelodiscus sinensis	97.51	0.00e+00	1731.00
IUUC-Pma-094695	Petromyzon marinus	80.89	0.00e+00	1437.00
IUUC-Pno-094785	Phaeosphaeria nodorum	62.41	1.00e-112	400.00
IUUC-Ppa-095911	Physcomitrella patens	62.95	0.00e+00	1127.00
IUUC-Pfo-096587	Poecilia formosa	86.14	0.00e+00	1669.00
IUUC-Pab-097926	Pongo abelii	96.82	0.00e+00	1744.00
IUUC-Pop-099634	Populus trichocarpa	62.11	0.00e+00	1103.00
IUUC-Pca-100965	Procavia capensis	96.69	0.00e+00	1772.00
IUUC-Ppe-101470	Prunus persica	62.59	0.00e+00	1117.00
IUUC-Pva-102451	Pteropus vampyrus	92.33	0.00e+00	1270.00
IUUC-Pgr-103590	Puccinia graminis	54.31	0.00e+00	927.00
IUUC-Ptt-103868	Puccinia triticina	54.55	0.00e+00	925.00
IUUC-Pte-104274	Pyrenophora teres	55.57	0.00e+00	963.00
IUUC-Pyt-104794	Pyrenophora triticirepentis	55.04	0.00e+00	912.00
IUUC-Rno-105979	Rattus norvegicus	84.26	0.00e+00	1262.00
IUUC-Sce-106269	Saccharomyces cerevisiae	47.30	0.00e+00	790.00
IUUC-Sha-106905	Sarcophilus harrisii	96.53	0.00e+00	1749.00
IUUC-Sja-107838	Schizosaccharomyces japonicus	47.47	0.00e+00	834.00
IUUC-Spo-108299	Schizosaccharomyces pombe	47.66	0.00e+00	837.00
IUUC-Smo-108695	Selaginella moellendorffii	61.60	0.00e+00	1071.00
IUUC-Sit-110692	Setaria italica	62.95	0.00e+00	1102.00
IUUC-Sly-111775	Solanum lycopersicum	62.38	0.00e+00	1094.00
IUUC-Stu-112906	Solanum tuberosum	62.23	0.00e+00	989.00
IUUC-Sar-113472	Sorex araneus	91.26	0.00e+00	1160.00
IUUC-Sbi-114052	Sorghum bicolor	63.16	0.00e+00	1114.00
IUUC-Sre-115040	Sporisorium reilianum	52.62	0.00e+00	917.00
IUUC-Ssc-115593	Sus scrofa	98.57	0.00e+00	1831.00
IUUC-Tgu-117239	Taeniopygia guttata	94.16	0.00e+00	1722.00
IUUC-Tru-118025	Takifugu rubripes	92.58	0.00e+00	1659.00
IUUC-Tsy-118824	Tarsius syrichta	90.61	0.00e+00	1169.00
IUUC-Tni-120142	Tetraodon nigroviridis	90.45	0.00e+00	1653.00
IUUC-Tca-121613	Theobroma cacao	59.01	0.00e+00	1113.00
IUUC-Tre-122072	Trichoderma reesei	55.12	0.00e+00	936.00
IUUC-Tvi-122546	Trichoderma virens	54.62	0.00e+00	922.00
IUUC-Tae-125292	Triticum aestivum	61.26	0.00e+00	1100.00
IUUC-Tur-126283	Triticum urartu	53.89	0.00e+00	942.00
IUUC-Tme-127041	Tuber melanosporum	56.54	0.00e+00	974.00
IUUC-Tbe-127770	Tupaia belangeri	92.17	0.00e+00	1269.00
IUUC-Ttr-129294	Tursiops truncatus	98.57	0.00e+00	1829.00
IUUC-Uma-129351	Ustilago maydis	51.16	0.00e+00	907.00
IUUC-Vda-129716	Verticillium dahliae	55.61	0.00e+00	958.00
IUUC-Vpa-130037	Vicugna pacos	89.15	0.00e+00	939.00
IUUC-Vvi-131689	Vitis vinifera	59.91	0.00e+00	1112.00
IUUC-Xtr-132633	Xenopus tropicalis	93.98	0.00e+00	1680.00
IUUC-Xma-133347	Xiphophorus maculatus	87.88	0.00e+00	1675.00
IUUC-Yli-134455	Yarrowia lipolytica	50.38	0.00e+00	838.00
IUUC-Zma-135706	Zea mays	61.78	0.00e+00	1120.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence