iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Psi-093948

Ensembl Protein ID

ENSPSIP00000012215.1

UniProt Accession

K7FW05; K7FW05_PELSI

Genbank Protein ID

ENSPSIP00000012215

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGCU01095575

Gene Name

TRAF6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000011001.1	ENSPSIT00000012274.1	ENSPSIP00000012215.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	1.50e-07	31.4	69	129

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 5    eflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplteedlvPnltlrrli 65
            + CpI l   r+ v +p+G+ + +++I k +++ g++cPv+++ l e++l P ++ +r i
   Q: 69   KYECPICLMALREAVQTPCGHRFCKACIVKSIRDAGHKCPVDNEILLENQLFPDNFAKREI 129
           688*****************************999999*****************999977 PP

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

MSLLHSDNSY RAKELESGCC AAMASACCAG AKEDSISVSV SSGTGNLPNS FTEEIQGYDV 60
DFDPPLENKY ECPICLMALR EAVQTPCGHR FCKACIVKSI RDAGHKCPVD NEILLENQLF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGCTTGC TACACAGTGA CAACAGCTAT AGAGCCAAAG AACTAGAGTC TGGCTGCTGT 60
GCAGCCATGG CTAGTGCATG CTGTGCTGGA GCTAAAGAAG ACAGCATAAG TGTCTCTGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR002083--MATH/TRAF_dom
IPR012227--TNF_rcpt--assoc_TRAF
IPR008974--TRAF-like
IPR027139--TRAF6
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
IPR001293--Znf_TRAF

PROSITE

PS50144--MATH
PS00518--ZF_RING_1
PS50089--ZF_RING_2
PS50145--ZF_TRAF

Pfam

PF02176--zf-TRAF

SMART

SM00061--MATH
SM00184--RING

Gene Ontology

GO:0035631--C:CD40 receptor complex
GO:0009898--C:cytoplasmic side of plasma membrane
GO:0005829--C:cytosol
GO:0005811--C:lipid particle
GO:0005634--C:nucleus
GO:0048471--C:perinuclear region of cytoplasm
GO:0043234--C:protein complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0007250--P:activation of NF-kappaB-inducing kinase activity
GO:0019886--P:antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0045453--P:bone resorption
GO:0048468--P:cell development
GO:0071222--P:cellular response to lipopolysaccharide
GO:0007249--P:I-kappaB kinase/NF-kappaB signaling
GO:0070498--P:interleukin-1-mediated signaling pathway
GO:0043011--P:myeloid dendritic cell differentiation
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0001843--P:neural tube closure
GO:0042475--P:odontogenesis of dentin-containing tooth
GO:0001503--P:ossification
GO:0030316--P:osteoclast differentiation
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045084--P:positive regulation of interleukin-12 biosynthetic process
GO:0032743--P:positive regulation of interleukin-2 production
GO:0045410--P:positive regulation of interleukin-6 biosynthetic process
GO:0043507--P:positive regulation of JUN kinase activity
GO:0031666--P:positive regulation of lipopolysaccharide-mediated signaling pathway
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0045672--P:positive regulation of osteoclast differentiation
GO:0002726--P:positive regulation of T cell cytokine production
GO:0042102--P:positive regulation of T cell proliferation
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:2000679--P:positive regulation of transcription regulatory region DNA binding
GO:0051865--P:protein autoubiquitination
GO:0070534--P:protein K63-linked ubiquitination
GO:0042981--P:regulation of apoptotic process
GO:0051023--P:regulation of immunoglobulin secretion
GO:0050852--P:T cell receptor signaling pathway
GO:0042088--P:T-helper 1 type immune response

KEGG

pss:102463398

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000797	Aegilops tauschii	34.67	7.00e-08	51.60
IUUC-Aml-001262	Ailuropoda melanoleuca	74.75	0.00e+00	791.00
IUUC-Apl-004062	Anas platyrhynchos	82.46	0.00e+00	935.00
IUUC-Aca-004636	Anolis carolinensis	77.55	0.00e+00	866.00
IUUC-Ame-011682	Astyanax mexicanus	55.56	6.00e-169	587.00
IUUC-Bta-012692	Bos taurus	72.18	0.00e+00	807.00
IUUC-Bci-013998	Botrytis cinerea	26.79	2.00e-12	66.60
IUUC-Cja-019426	Callithrix jacchus	71.85	0.00e+00	793.00
IUUC-Cfa-020948	Canis familiaris	71.34	0.00e+00	709.00
IUUC-Cpo-021378	Cavia porcellus	71.85	0.00e+00	792.00
IUUC-Csa-024045	Chlorocebus sabaeus	71.30	0.00e+00	803.00
IUUC-Cho-024973	Choloepus hoffmanni	63.55	6.00e-78	284.00
IUUC-Csv-026300	Ciona savignyi	41.96	3.00e-47	181.00
IUUC-Dre-027557	Danio rerio	58.14	1.00e-177	615.00
IUUC-Dno-030032	Dasypus novemcinctus	69.28	5.00e-119	420.00
IUUC-Dor-030790	Dipodomys ordii	72.03	0.00e+00	793.00
IUUC-Dme-031921	Drosophila melanogaster	27.11	3.00e-40	159.00
IUUC-Ete-032952	Echinops telfairi	69.10	2.00e-144	505.00
IUUC-Eca-033924	Equus caballus	69.35	0.00e+00	709.00
IUUC-Eeu-034734	Erinaceus europaeus	66.93	0.00e+00	714.00
IUUC-Fca-036222	Felis catus	69.01	0.00e+00	714.00
IUUC-Fal-036834	Ficedula albicollis	84.93	0.00e+00	853.00
IUUC-Fox-037935	Fusarium oxysporum	30.65	9.00e-21	94.70
IUUC-Gmo-039061	Gadus morhua	60.38	8.00e-91	327.00
IUUC-Ggr-040084	Gaeumannomyces graminis	24.89	1.00e-13	71.20
IUUC-Gga-040599	Gallus gallus	83.55	0.00e+00	945.00
IUUC-Gac-041977	Gasterosteus aculeatus	56.14	4.00e-176	610.00
IUUC-Ggo-044508	Gorilla gorilla	67.94	0.00e+00	736.00
IUUC-Hsa-046349	Homo sapiens	71.48	0.00e+00	807.00
IUUC-Itr-047966	Ictidomys tridecemlineatus	71.48	0.00e+00	800.00
IUUC-Lch-049821	Latimeria chalumnae	70.48	0.00e+00	795.00
IUUC-Loc-051995	Lepisosteus oculatus	61.36	0.00e+00	640.00
IUUC-Laf-054115	Loxodonta africana	70.75	0.00e+00	788.00
IUUC-Mcc-055298	Macaca mulatta	70.93	0.00e+00	797.00
IUUC-Mor-057263	Magnaporthe oryzae	33.79	1.00e-20	94.70
IUUC-Mpo-057517	Magnaporthe poae	28.43	3.00e-15	76.30
IUUC-Mga-059340	Meleagris gallopavo	83.91	0.00e+00	944.00
IUUC-Mvi-060553	Microbotryum violaceum	26.98	8.00e-16	78.20
IUUC-Mmr-061063	Microcebus murinus	71.85	0.00e+00	789.00
IUUC-Mdo-062075	Monodelphis domestica	72.21	0.00e+00	800.00
IUUC-Mmu-063780	Mus musculus	72.64	0.00e+00	777.00
IUUC-Mpu-065748	Mustela putorius furo	71.96	0.00e+00	803.00
IUUC-Mlu-067888	Myotis lucifugus	72.75	0.00e+00	799.00
IUUC-Ncr-068632	Neurospora crassa	25.47	4.00e-15	76.30
IUUC-Nle-069234	Nomascus leucogenys	71.12	0.00e+00	803.00
IUUC-Opr-070393	Ochotona princeps	77.93	3.00e-103	368.00
IUUC-Ont-072459	Oreochromis niloticus	58.58	1.00e-180	625.00
IUUC-Oan-073578	Ornithorhynchus anatinus	76.42	0.00e+00	850.00
IUUC-Ocu-074201	Oryctolagus cuniculus	73.96	0.00e+00	803.00
IUUC-Oni-083040	Oryza nivara	32.00	2.00e-06	45.80
IUUC-Ola-087319	Oryzias latipes	62.03	1.00e-89	323.00
IUUC-Olu-087748	Ostreococcus lucimarinus	22.33	2.00e-10	59.30
IUUC-Oga-087936	Otolemur garnettii	71.99	0.00e+00	785.00
IUUC-Oar-089379	Ovis aries	72.13	0.00e+00	808.00
IUUC-Ptr-090758	Pan troglodytes	71.48	0.00e+00	804.00
IUUC-Pan-092590	Papio anubis	71.12	0.00e+00	799.00
IUUC-Pma-094434	Petromyzon marinus	46.24	6.00e-128	451.00
IUUC-Pfo-096912	Poecilia formosa	55.76	6.00e-173	600.00
IUUC-Pab-097651	Pongo abelii	71.48	0.00e+00	806.00
IUUC-Pca-100958	Procavia capensis	67.93	2.00e-167	581.00
IUUC-Pva-103247	Pteropus vampyrus	73.62	4.00e-104	371.00
IUUC-Pte-104279	Pyrenophora teres	27.40	6.00e-13	69.30
IUUC-Pyt-104429	Pyrenophora triticirepentis	28.31	4.00e-13	69.30
IUUC-Rno-104994	Rattus norvegicus	69.75	0.00e+00	792.00
IUUC-Sha-106494	Sarcophilus harrisii	73.31	0.00e+00	813.00
IUUC-Ssl-108580	Sclerotinia sclerotiorum	27.78	3.00e-12	66.60
IUUC-Sar-113375	Sorex araneus	71.95	0.00e+00	791.00
IUUC-Sre-115218	Sporisorium reilianum	28.40	6.00e-18	85.50
IUUC-Ssc-115417	Sus scrofa	72.58	0.00e+00	814.00
IUUC-Tgu-117232	Taeniopygia guttata	84.40	0.00e+00	906.00
IUUC-Tru-118321	Takifugu rubripes	57.03	4.00e-175	607.00
IUUC-Tni-120475	Tetraodon nigroviridis	58.30	1.00e-170	592.00
IUUC-Tur-126067	Triticum urartu	34.67	6.00e-08	51.20
IUUC-Tbe-127719	Tupaia belangeri	62.66	0.00e+00	663.00
IUUC-Ttr-129264	Tursiops truncatus	74.02	8.00e-103	367.00
IUUC-Uma-129620	Ustilago maydis	26.20	1.00e-16	81.60
IUUC-Vpa-130244	Vicugna pacos	76.08	4.00e-107	381.00
IUUC-Xtr-131948	Xenopus tropicalis	67.44	0.00e+00	758.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence