iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000011066.1	ENSLACT00000012654.1	ENSLACP00000012560.1
ENSLACG00000011066.1	ENSLACT00000012655.1	ENSLACP00000012561.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.20e-24	86.5	31	349

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNl..gNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkk....avsprellkalkkeaeef 84
           Gl N   +N+C++NS++Q+L+++  +r+ + +   +++  e      +++ ++l+++f+++++s +k     +  ++l +++k+e+ +f
   Q: 31   GLLNApgQNSCFLNSAVQVLWQLDIFRRSFRQLPGHTCMGE------ACIFCALKSMFAQFQHSPEKalpsDILRNALAESFKDEH-RF 112
           66666558************************888888875......7*************8666661111444444555555554.59 PP
   S: 85   sgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldls 173
           +     Da E+++ +l++++ ++                     ++e +  ++++++ ++ F ++l +q +c +c+ +s    pf++l 
   Q: 113  QLGLMDDAAECFENILERIHFHI-------------------VPNSEADMCTSKSCITHQKFAMTLYEQSVCRSCGATSDPL-PFVELV 181
           9**********************...................122356789999***********************99665.899999 PP
   S: 174  lpvpgkeetkke........slq.dcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkv 253
             v+    +++          l+ d++ +  ++ +  g+ +   ++c +k + ++   l ++Pe+ ++ L +   se+ +  e + +++
   Q: 182  HYVSITALCNQVdrmierheRLKpDMFGELLQAASTAGDYRNCPSNCGQKIKIRRV--LMNCPEIVTIGLVWD--SENSDLTEDVIRYL 266
           9999555554445555555556548999**********99999999*999975554..6689***********..77777887788877 PP
   S: 254  efpleLdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtev..keeevleetg...staYvlfYk 336
              l L    + ++  ++q+++ +  L+++v++s      HY+a+++++k + W+ fdD +V+ev  k+++v++++     ++ +lfY 
   Q: 267  GPQLFLPGLFYRVT--DEQAKRSELLLVGMVCYSN----KHYCAFAYHTKSSkWVFFDDAHVKEVgsKWKDVVSKCVrchFQPLLLFYS 349
           74433444434444..55556999*********97....9********77767***********9767899999766888899999996 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

MAWVKFFKKP GGNLGKSYQP GSMLSLAPTK GLLNAPGQNS CFLNSAVQVL WQLDIFRRSF 60
RQLPGHTCMG EACIFCALKS MFAQFQHSPE KALPSDILRN ALAESFKDEH RFQLGLMDDA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GACTTCTATT GCAGAGAGGG AAACTGAAGC AATGGAAATC GATGCACTTG TATACTCTGT 60
GGCTCAAGTT GTTGATTTGA AAGTAAAGAA ATCTTTATAT TAAAATGGTC TCTGTGAATG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR028889--USP_dom

PROSITE

PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination

KEGG

lcm:102365346

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002136	Ailuropoda melanoleuca	60.82	0.00e+00	912.00
IUUC-Atr-002451	Amborella trichopoda	31.43	3.00e-37	151.00
IUUC-Apl-003843	Anas platyrhynchos	51.04	0.00e+00	999.00
IUUC-Aca-004689	Anolis carolinensis	49.73	0.00e+00	921.00
IUUC-Ame-010673	Astyanax mexicanus	71.66	0.00e+00	657.00
IUUC-Bta-012434	Bos taurus	59.75	0.00e+00	899.00
IUUC-Cja-019625	Callithrix jacchus	61.56	0.00e+00	919.00
IUUC-Cfa-020038	Canis familiaris	56.04	0.00e+00	917.00
IUUC-Cpo-021503	Cavia porcellus	59.10	0.00e+00	923.00
IUUC-Csa-024021	Chlorocebus sabaeus	60.66	0.00e+00	905.00
IUUC-Cho-024769	Choloepus hoffmanni	57.07	0.00e+00	777.00
IUUC-Dre-028381	Danio rerio	54.62	0.00e+00	699.00
IUUC-Dno-029317	Dasypus novemcinctus	62.87	0.00e+00	880.00
IUUC-Dor-030249	Dipodomys ordii	81.18	0.00e+00	677.00
IUUC-Ete-032403	Echinops telfairi	60.85	0.00e+00	917.00
IUUC-Eca-033216	Equus caballus	61.18	0.00e+00	900.00
IUUC-Eeu-035319	Erinaceus europaeus	49.90	9.00e-127	447.00
IUUC-Fca-036414	Felis catus	61.49	0.00e+00	909.00
IUUC-Fal-036886	Ficedula albicollis	60.80	0.00e+00	950.00
IUUC-Gmo-038617	Gadus morhua	77.35	2.00e-175	607.00
IUUC-Gga-040930	Gallus gallus	50.93	0.00e+00	1029.00
IUUC-Gac-041327	Gasterosteus aculeatus	78.95	2.00e-178	617.00
IUUC-Ggo-045573	Gorilla gorilla	49.61	0.00e+00	932.00
IUUC-Hsa-046741	Homo sapiens	59.90	0.00e+00	896.00
IUUC-Itr-048229	Ictidomys tridecemlineatus	59.12	0.00e+00	799.00
IUUC-Lpe-051572	Leersia perrieri	31.74	1.00e-37	152.00
IUUC-Loc-052180	Lepisosteus oculatus	62.33	0.00e+00	915.00
IUUC-Laf-054545	Loxodonta africana	49.69	0.00e+00	953.00
IUUC-Mcc-054918	Macaca mulatta	60.79	0.00e+00	908.00
IUUC-Meu-056802	Macropus eugenii	57.73	0.00e+00	777.00
IUUC-Mga-059684	Meleagris gallopavo	49.74	0.00e+00	961.00
IUUC-Mmr-061644	Microcebus murinus	80.65	1.00e-171	595.00
IUUC-Mdo-062636	Monodelphis domestica	59.56	0.00e+00	862.00
IUUC-Mmu-063910	Mus musculus	62.10	0.00e+00	858.00
IUUC-Mac-064469	Musa acuminata	32.77	5.00e-20	94.00
IUUC-Mpu-065796	Mustela putorius furo	48.19	0.00e+00	882.00
IUUC-Nle-069276	Nomascus leucogenys	61.34	0.00e+00	848.00
IUUC-Opr-070545	Ochotona princeps	51.02	2.00e-129	457.00
IUUC-Ont-072449	Oreochromis niloticus	54.90	0.00e+00	742.00
IUUC-Oan-073493	Ornithorhynchus anatinus	54.55	0.00e+00	653.00
IUUC-Ocu-074445	Oryctolagus cuniculus	47.67	0.00e+00	920.00
IUUC-Olo-080872	Oryza longistaminata	29.85	2.00e-33	138.00
IUUC-Ola-087574	Oryzias latipes	69.25	2.00e-163	568.00
IUUC-Oga-087977	Otolemur garnettii	48.44	0.00e+00	872.00
IUUC-Oar-089584	Ovis aries	58.99	0.00e+00	884.00
IUUC-Ptr-091610	Pan troglodytes	49.69	0.00e+00	922.00
IUUC-Pan-091828	Papio anubis	56.94	0.00e+00	807.00
IUUC-Psi-093643	Pelodiscus sinensis	65.53	0.00e+00	978.00
IUUC-Ppa-095930	Physcomitrella patens	28.57	8.00e-37	150.00
IUUC-Pfo-096829	Poecilia formosa	62.76	0.00e+00	653.00
IUUC-Pab-098190	Pongo abelii	49.43	0.00e+00	913.00
IUUC-Pva-102372	Pteropus vampyrus	59.62	0.00e+00	828.00
IUUC-Sha-107092	Sarcophilus harrisii	61.15	0.00e+00	866.00
IUUC-Sar-113376	Sorex araneus	49.19	2.00e-107	383.00
IUUC-Ssc-115969	Sus scrofa	60.28	0.00e+00	891.00
IUUC-Tgu-117134	Taeniopygia guttata	64.22	0.00e+00	962.00
IUUC-Tru-117981	Takifugu rubripes	69.64	2.00e-172	598.00
IUUC-Tsy-119297	Tarsius syrichta	53.68	0.00e+00	702.00
IUUC-Tni-120116	Tetraodon nigroviridis	78.30	2.00e-176	611.00
IUUC-Tbe-127607	Tupaia belangeri	61.89	0.00e+00	894.00
IUUC-Ttr-128647	Tursiops truncatus	58.82	0.00e+00	842.00
IUUC-Vpa-130288	Vicugna pacos	56.04	0.00e+00	812.00
IUUC-Xtr-132277	Xenopus tropicalis	59.54	0.00e+00	841.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence