iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000017068.1	ENSAMET00000018786.1	ENSAMEP00000018055.1
ENSAMEG00000017068.1	ENSAMET00000018791.1	ENSAMEP00000018060.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	5.00e-15	55.3	181	235

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           +v++ ++++ +n+deL+++kGdv++v     +++gW++g  + +g+ G fP+n+v++++
   Q: 181  VVRAKFSFQQTNEDELSFTKGDVIHVT--RVEEGGWWEG--THNGRTGWFPSNYVREIK 235
           78999*********************7..999*******..8**************996 PP

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

XXEQTVTWLI TLGVLESPKK TISDPEGFLQ ASLKDGVVLC XXXQRLCSVL QVYPEPRSES 60
ECLSNIREFL RGCGASLRLE VSGQRVRDPT NLFNFSFQTF DANDLYQGQN FNKVLSSLVT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

NNNNCCGAGC AGACCGTTAC GTGGCTCATC ACCTTGGGGG TGCTGGAGTC GCCCAAGAAA 60
ACCATCTCGG ACCCGGAGGG CTTCCTGCAG GCGTCTCTGA AGGATGGGGT GGTCCTCTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001715--CH-domain
IPR000219--DH-domain
IPR001331--GDS_CDC24_CS
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS50021--CH
PS00741--DH_1
PS50010--DH_2
PS50003--PH_DOMAIN
PS50002--SH3

Pfam

PF00169--PH
PF00621--RhoGEF
PF07653--SH3_2

PRINTS

PR00452--SH3DOMAIN

SMART

SM00233--PH
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005829--C:cytosol
GO:0005925--C:focal adhesion
GO:0030027--C:lamellipodium
GO:0043005--C:neuron projection
GO:0043025--C:neuronal cell body
GO:0005886--C:plasma membrane
GO:0043234--C:protein complex
GO:0000322--C:storage vacuole
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0048041--P:focal adhesion assembly
GO:0007030--P:Golgi organization
GO:0002244--P:hematopoietic progenitor cell differentiation
GO:0035556--P:intracellular signal transduction
GO:0030032--P:lamellipodium assembly
GO:0043065--P:positive regulation of apoptotic process
GO:0010763--P:positive regulation of fibroblast migration
GO:0060124--P:positive regulation of growth hormone secretion
GO:2000394--P:positive regulation of lamellipodium morphogenesis
GO:0032092--P:positive regulation of protein binding
GO:1900026--P:positive regulation of substrate adhesion-dependent cell spreading
GO:1904424--P:regulation of GTP binding
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aca-004591	Anolis carolinensis	88.54	0.00e+00	1226.00
IUUC-Ame-010759	Astyanax mexicanus	73.23	0.00e+00	1105.00
IUUC-Bta-013328	Bos taurus	89.17	0.00e+00	1296.00
IUUC-Cja-018742	Callithrix jacchus	94.89	0.00e+00	1228.00
IUUC-Cfa-020756	Canis familiaris	97.78	0.00e+00	1184.00
IUUC-Cpo-021284	Cavia porcellus	89.74	0.00e+00	1232.00
IUUC-Csa-023162	Chlorocebus sabaeus	91.97	0.00e+00	1325.00
IUUC-Cho-024736	Choloepus hoffmanni	73.62	4.00e-174	604.00
IUUC-Cin-025535	Ciona intestinalis	39.92	8.00e-95	340.00
IUUC-Cgl-026676	Colletotrichum gloeosporioides	44.29	2.00e-11	65.50
IUUC-Cne-026866	Cryptococcus neoformans	49.21	2.00e-12	68.60
IUUC-Dre-028646	Danio rerio	73.35	0.00e+00	1101.00
IUUC-Dno-029461	Dasypus novemcinctus	92.48	0.00e+00	1323.00
IUUC-Dor-030623	Dipodomys ordii	83.69	0.00e+00	1103.00
IUUC-Dme-032219	Drosophila melanogaster	45.34	6.00e-103	369.00
IUUC-Ete-032236	Echinops telfairi	80.65	0.00e+00	813.00
IUUC-Eca-034137	Equus caballus	96.66	0.00e+00	1206.00
IUUC-Fca-035742	Felis catus	97.77	0.00e+00	1148.00
IUUC-Fal-037205	Ficedula albicollis	93.16	0.00e+00	1026.00
IUUC-Gmo-039475	Gadus morhua	72.87	0.00e+00	960.00
IUUC-Gga-040539	Gallus gallus	92.97	0.00e+00	980.00
IUUC-Gac-042615	Gasterosteus aculeatus	70.27	0.00e+00	901.00
IUUC-Ggo-044470	Gorilla gorilla	94.02	0.00e+00	1208.00
IUUC-Hsa-046398	Homo sapiens	91.99	0.00e+00	1346.00
IUUC-Kpa-049278	Komagataella pastoris	26.36	2.00e-16	81.30
IUUC-Loc-052146	Lepisosteus oculatus	82.32	0.00e+00	1192.00
IUUC-Laf-053891	Loxodonta africana	89.16	0.00e+00	1301.00
IUUC-Mcc-055483	Macaca mulatta	91.86	0.00e+00	1346.00
IUUC-Mga-059410	Meleagris gallopavo	92.76	0.00e+00	1166.00
IUUC-Mmr-060758	Microcebus murinus	92.96	0.00e+00	1301.00
IUUC-Mdo-061900	Monodelphis domestica	90.08	0.00e+00	1249.00
IUUC-Mmu-063849	Mus musculus	90.95	0.00e+00	1285.00
IUUC-Mpu-065876	Mustela putorius furo	96.98	0.00e+00	1164.00
IUUC-Mlu-067970	Myotis lucifugus	96.37	0.00e+00	1206.00
IUUC-Nle-069685	Nomascus leucogenys	91.35	0.00e+00	1029.00
IUUC-Opr-071132	Ochotona princeps	63.47	0.00e+00	721.00
IUUC-Ont-071815	Oreochromis niloticus	74.21	0.00e+00	1095.00
IUUC-Oan-073057	Ornithorhynchus anatinus	92.67	0.00e+00	1043.00
IUUC-Ola-086663	Oryzias latipes	72.26	0.00e+00	950.00
IUUC-Oga-088103	Otolemur garnettii	94.36	0.00e+00	1144.00
IUUC-Ptr-091162	Pan troglodytes	94.01	0.00e+00	1293.00
IUUC-Pan-092093	Papio anubis	81.80	0.00e+00	1178.00
IUUC-Pma-094701	Petromyzon marinus	56.18	1.00e-126	446.00
IUUC-Pfo-096736	Poecilia formosa	69.25	0.00e+00	988.00
IUUC-Pab-097641	Pongo abelii	91.46	0.00e+00	1265.00
IUUC-Pva-102819	Pteropus vampyrus	89.70	0.00e+00	1281.00
IUUC-Pgr-103400	Puccinia graminis	27.00	1.00e-19	92.40
IUUC-Rno-106099	Rattus norvegicus	90.70	0.00e+00	1258.00
IUUC-Sha-106845	Sarcophilus harrisii	92.41	0.00e+00	1124.00
IUUC-Ssc-116036	Sus scrofa	93.99	0.00e+00	1131.00
IUUC-Tgu-117498	Taeniopygia guttata	87.52	0.00e+00	1237.00
IUUC-Tru-118278	Takifugu rubripes	71.72	0.00e+00	959.00
IUUC-Tsy-118990	Tarsius syrichta	94.30	0.00e+00	972.00
IUUC-Tni-120852	Tetraodon nigroviridis	71.66	0.00e+00	972.00
IUUC-Ttr-128922	Tursiops truncatus	88.49	0.00e+00	1164.00
IUUC-Xtr-132012	Xenopus tropicalis	81.17	0.00e+00	1068.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence