iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-033962

UUCD1 version

UUC-EqC-00393

Ensembl Protein ID

ENSECAP00000021924.1

UniProt Accession

F6WHL3; F6WHL3_HORSE

Protein Name

Uncharacterized protein

Gene Name

TRIM38

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000024438.1	ENSECAT00000026293.1	ENSECAP00000021924.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	9.60e-09	35.4	12	84

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 4    eeflCpIslelMrdPvvlpsGitydrssIekwlasggk........tcPvtrqplteedlvPnltlrrliqaw 68
           ee  C+I l+lM +Pv +++G++y   +I +++++ +         +cP +r++++  +l Pn+ l  li+a 
   Q: 12   EEATCSICLNLMVEPVSVSCGHSYCHLCIVRFIENVRLlqpwlgtfSCPQCRATFQMASLRPNKQLGTLIEAI 84
           6889*****************************999989999************************9999875 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MASSGNAKKM REEATCSICL NLMVEPVSVS CGHSYCHLCI VRFIENVRLL QPWLGTFSCP 60
QCRATFQMAS LRPNKQLGTL IEAIREMEHE MSCEEHGEKL HLFCEDEGQL ICWRCERTPQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATCACTGTGG GAAAATTCTG CCTGCTTCAT CTCTGCCTCT AGATCCAGTG CTGGAGCTTT 60
TCAGGAAAAG CCATGGCTTC ATCCGGAAAC GCCAAGAAGA TGAGGGAGGA AGCCACCTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY
PF00643--zf-B_box

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00336--BBOX
SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005622--C:intracellular
GO:0004871--F:signal transducer activity
GO:0008270--F:zinc ion binding
GO:0050687--P:negative regulation of defense response to virus
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0046598--P:positive regulation of viral entry into host cell
GO:0045070--P:positive regulation of viral genome replication
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0070936--P:protein K48-linked ubiquitination
GO:0032648--P:regulation of interferon-beta production

KEGG

ecb:100052917

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001649	Ailuropoda melanoleuca	77.37	0.00e+00	756.00
IUUC-Aly-006134	Arabidopsis lyrata	36.67	9.00e-07	47.40
IUUC-Ago-007781	Ashbya gossypii	35.63	1.00e-09	57.80
IUUC-Bta-012574	Bos taurus	82.14	0.00e+00	789.00
IUUC-Cja-019759	Callithrix jacchus	76.79	0.00e+00	682.00
IUUC-Cfa-020431	Canis familiaris	75.91	0.00e+00	728.00
IUUC-Cpo-022541	Cavia porcellus	65.67	0.00e+00	648.00
IUUC-Csa-023320	Chlorocebus sabaeus	75.70	0.00e+00	731.00
IUUC-Cho-024964	Choloepus hoffmanni	70.73	4.00e-131	460.00
IUUC-Dno-029741	Dasypus novemcinctus	67.67	0.00e+00	642.00
IUUC-Dor-030298	Dipodomys ordii	63.05	5.00e-107	380.00
IUUC-Ete-032493	Echinops telfairi	63.66	4.00e-175	607.00
IUUC-Eeu-035228	Erinaceus europaeus	72.17	3.00e-143	501.00
IUUC-Fca-036349	Felis catus	76.56	0.00e+00	742.00
IUUC-Ggo-044493	Gorilla gorilla	77.63	0.00e+00	751.00
IUUC-Hsa-046161	Homo sapiens	77.20	0.00e+00	748.00
IUUC-Itr-048162	Ictidomys tridecemlineatus	61.39	5.00e-152	530.00
IUUC-Lch-049738	Latimeria chalumnae	35.87	8.00e-69	254.00
IUUC-Laf-054150	Loxodonta africana	75.27	0.00e+00	711.00
IUUC-Mcc-055076	Macaca mulatta	75.91	0.00e+00	735.00
IUUC-Mmu-063517	Mus musculus	55.11	2.00e-146	512.00
IUUC-Mpu-065752	Mustela putorius furo	76.51	0.00e+00	751.00
IUUC-Mlu-067758	Myotis lucifugus	60.83	3.00e-153	535.00
IUUC-Nle-069117	Nomascus leucogenys	77.59	0.00e+00	746.00
IUUC-Opr-071144	Ochotona princeps	68.17	0.00e+00	631.00
IUUC-Ocu-074825	Oryctolagus cuniculus	70.97	0.00e+00	687.00
IUUC-Oga-088744	Otolemur garnettii	72.88	2.00e-127	447.00
IUUC-Oar-089951	Ovis aries	81.92	0.00e+00	791.00
IUUC-Ptr-090519	Pan troglodytes	77.42	0.00e+00	749.00
IUUC-Pan-092059	Papio anubis	75.91	0.00e+00	736.00
IUUC-Pab-098747	Pongo abelii	78.28	0.00e+00	757.00
IUUC-Pca-100294	Procavia capensis	69.89	0.00e+00	682.00
IUUC-Pva-102129	Pteropus vampyrus	69.25	0.00e+00	679.00
IUUC-Sar-113760	Sorex araneus	65.95	8.00e-170	589.00
IUUC-Tsy-119422	Tarsius syrichta	73.55	0.00e+00	685.00
IUUC-Tbe-127628	Tupaia belangeri	64.26	7.00e-105	373.00
IUUC-Ttr-129039	Tursiops truncatus	84.95	0.00e+00	826.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence