iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Itr-048486

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTP01068846

Gene Name

PIAS4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000012472.2	ENSSTOT00000012474.2	ENSSTOP00000011180.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	90.89	0.00e+00	885.00	IUUC-Hsa-045784
E3 activity/RING/RING	33.91	5.00e-28	120.00	IUUC-Sce-106398

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

SMCVVALLQN MVMSFRVSDL QMLLGFVGRS KSGLKHELVT RALQLVQFDC SPELFKKIKE 60
LYETRYAKKS AEPGPQPHRP LDPLTMHSAY DRASTVPRTP LSGPNIDYPV LYGKYLNGLG 120

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Nucleotide Sequence
(Fasta)

AGCATGTGTG TGGTTGCTCT TCTTCAGAAC ATGGTGATGA GTTTCCGAGT CTCCGACCTC 60
CAGATGCTGC TGGGATTCGT GGGCCGCAGC AAGAGCGGGC TGAAGCACGA GCTCGTCACC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR027224--PIAS4
IPR023321--PINIT
IPR003034--SAP_dom
IPR004181--Znf_MIZ

PROSITE

PS51466--PINIT
PS50800--SAP
PS51044--ZF_SP_RING

Pfam

PF14324--PINIT
PF02891--zf-MIZ

SMART

SM00513--SAP

Gene Ontology

GO:0005737--C:cytoplasm
GO:0016363--C:nuclear matrix
GO:0005654--C:nucleoplasm
GO:1990234--C:transferase complex
GO:0003677--F:DNA binding
GO:0061665--F:SUMO ligase activity
GO:0003714--F:transcription corepressor activity
GO:0008270--F:zinc ion binding
GO:0032088--P:negative regulation of NF-kappaB transcription factor activity
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0010804--P:negative regulation of tumor necrosis factor-mediated signaling pathway
GO:1902231--P:positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage
GO:1902174--P:positive regulation of keratinocyte apoptotic process
GO:0033235--P:positive regulation of protein sumoylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001745	Ailuropoda melanoleuca	90.66	0.00e+00	877.00
IUUC-Apl-003765	Anas platyrhynchos	79.92	0.00e+00	819.00
IUUC-Ame-010763	Astyanax mexicanus	58.86	2.00e-142	498.00
IUUC-Bta-012369	Bos taurus	93.07	0.00e+00	888.00
IUUC-Bra-017443	Brassica rapa	30.30	2.00e-17	84.00
IUUC-Cja-019450	Callithrix jacchus	91.88	0.00e+00	892.00
IUUC-Cfa-020933	Canis familiaris	90.53	0.00e+00	877.00
IUUC-Cpo-022112	Cavia porcellus	92.06	0.00e+00	853.00
IUUC-Csa-023913	Chlorocebus sabaeus	78.98	0.00e+00	716.00
IUUC-Cgl-026533	Colletotrichum gloeosporioides	27.54	7.00e-34	138.00
IUUC-Dre-027609	Danio rerio	58.39	2.00e-138	485.00
IUUC-Dno-029664	Dasypus novemcinctus	75.62	4.00e-156	544.00
IUUC-Ete-032988	Echinops telfairi	91.59	4.00e-168	583.00
IUUC-Eca-034430	Equus caballus	87.65	0.00e+00	858.00
IUUC-Fca-035968	Felis catus	95.89	1.00e-166	578.00
IUUC-Fal-037449	Ficedula albicollis	82.02	0.00e+00	799.00
IUUC-Gmo-038925	Gadus morhua	60.40	2.00e-135	475.00
IUUC-Ggr-039896	Gaeumannomyces graminis	33.33	4.00e-30	125.00
IUUC-Gga-040362	Gallus gallus	84.33	0.00e+00	835.00
IUUC-Gac-042353	Gasterosteus aculeatus	58.33	6.00e-129	454.00
IUUC-Ggo-044810	Gorilla gorilla	89.31	0.00e+00	848.00
IUUC-Hsa-045784	Homo sapiens	91.49	0.00e+00	895.00
IUUC-Lch-049727	Latimeria chalumnae	70.57	2.00e-152	531.00
IUUC-Lpe-050926	Leersia perrieri	42.11	7.00e-20	92.40
IUUC-Loc-052354	Lepisosteus oculatus	62.42	2.00e-102	365.00
IUUC-Laf-054261	Loxodonta africana	91.12	0.00e+00	887.00
IUUC-Mcc-054931	Macaca mulatta	90.50	0.00e+00	878.00
IUUC-Meu-056468	Macropus eugenii	85.18	0.00e+00	852.00
IUUC-Mpo-057405	Magnaporthe poae	33.47	7.00e-29	121.00
IUUC-Mtr-058267	Medicago truncatula	33.33	2.00e-18	87.40
IUUC-Mga-059981	Meleagris gallopavo	89.66	0.00e+00	701.00
IUUC-Mvi-060421	Microbotryum violaceum	29.45	4.00e-28	119.00
IUUC-Mmr-061181	Microcebus murinus	88.89	0.00e+00	850.00
IUUC-Mdo-062345	Monodelphis domestica	84.98	0.00e+00	853.00
IUUC-Mmu-063197	Mus musculus	87.15	0.00e+00	841.00
IUUC-Mpu-066275	Mustela putorius furo	90.96	0.00e+00	881.00
IUUC-Mlu-067194	Myotis lucifugus	90.93	0.00e+00	883.00
IUUC-Ncr-068929	Neurospora crassa	26.42	1.00e-27	117.00
IUUC-Ont-072227	Oreochromis niloticus	58.80	2.00e-135	475.00
IUUC-Obr-076179	Oryza brachyantha	33.15	2.00e-21	97.40
IUUC-Olo-080772	Oryza longistaminata	37.84	1.00e-14	74.70
IUUC-Opu-083841	Oryza punctata	41.90	1.00e-20	95.10
IUUC-Ola-086865	Oryzias latipes	56.89	1.00e-133	469.00
IUUC-Oga-088945	Otolemur garnettii	91.29	0.00e+00	897.00
IUUC-Oar-089412	Ovis aries	90.14	0.00e+00	864.00
IUUC-Ptr-091550	Pan troglodytes	84.64	0.00e+00	632.00
IUUC-Pan-092183	Papio anubis	90.50	0.00e+00	892.00
IUUC-Psi-093003	Pelodiscus sinensis	83.93	0.00e+00	832.00
IUUC-Ppa-095583	Physcomitrella patens	40.00	5.00e-21	96.30
IUUC-Pfo-096704	Poecilia formosa	59.08	2.00e-138	485.00
IUUC-Pab-097923	Pongo abelii	96.25	0.00e+00	747.00
IUUC-Pca-100249	Procavia capensis	75.90	2.00e-142	498.00
IUUC-Pva-102562	Pteropus vampyrus	89.84	0.00e+00	844.00
IUUC-Rno-105762	Rattus norvegicus	86.96	0.00e+00	846.00
IUUC-Sce-106398	Saccharomyces cerevisiae	33.91	7.00e-29	122.00
IUUC-Sha-107253	Sarcophilus harrisii	85.18	0.00e+00	853.00
IUUC-Sja-107662	Schizosaccharomyces japonicus	26.67	1.00e-29	125.00
IUUC-Sar-113149	Sorex araneus	86.92	3.00e-125	441.00
IUUC-Ssc-115241	Sus scrofa	92.67	0.00e+00	897.00
IUUC-Tgu-116884	Taeniopygia guttata	82.57	0.00e+00	810.00
IUUC-Tru-118031	Takifugu rubripes	59.03	6.00e-141	493.00
IUUC-Tni-119766	Tetraodon nigroviridis	58.22	4.00e-137	481.00
IUUC-Tre-122003	Trichoderma reesei	29.94	3.00e-29	123.00
IUUC-Tme-126880	Tuber melanosporum	28.03	2.00e-25	110.00
IUUC-Ttr-128556	Tursiops truncatus	82.68	0.00e+00	733.00
IUUC-Vda-129985	Verticillium dahliae	34.26	1.00e-30	127.00
IUUC-Xtr-131866	Xenopus tropicalis	76.13	0.00e+00	748.00
IUUC-Xma-133963	Xiphophorus maculatus	58.76	1.00e-131	462.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence