iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066275

Ensembl Protein ID

ENSMPUP00000004459.1

UniProt Accession

M3XZF8; M3XZF8_MUSPF

Genbank Protein ID

ENSMPUP00000004459

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01077217

Gene Name

PIAS4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000004495.1	ENSMPUT00000004538.1	ENSMPUP00000004459.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	92.22	0.00e+00	899.00	IUUC-Hsa-045784
E3 activity/RING/RING	33.53	7.00e-28	120.00	IUUC-Sce-106398

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

FAAWAVLRKN MVMSFRVSDL QMLLGFVGRS KSGLKHELVT RALQLVQFDC SPELFKKIKE 60
LYETRYAKKS SEPVPQPHRP MDPLTMHSTY DRAGTVPRTP LSGPNIDYPV LYGKYLNGLG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTGCTGCGT GGGCAGTGCT GAGGAAGGTT TGAAGAGGAG GAGGGGAGCA GGGCTGAGCT 60
GGGGAGGGGG CATCACGGGG ATGGGTGAGC GGGGGCCTGA GCACAGGCAT GGAAGGGACT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR027224--PIAS4
IPR023321--PINIT
IPR003034--SAP_dom
IPR004181--Znf_MIZ
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51466--PINIT
PS50800--SAP
PS51044--ZF_SP_RING

Pfam

PF14324--PINIT
PF02891--zf-MIZ

SMART

SM00513--SAP

Gene Ontology

GO:0005737--C:cytoplasm
GO:0016363--C:nuclear matrix
GO:0005654--C:nucleoplasm
GO:1990234--C:transferase complex
GO:0003677--F:DNA binding
GO:0061665--F:SUMO ligase activity
GO:0003714--F:transcription corepressor activity
GO:0008270--F:zinc ion binding
GO:0032088--P:negative regulation of NF-kappaB transcription factor activity
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0010804--P:negative regulation of tumor necrosis factor-mediated signaling pathway
GO:1902231--P:positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage
GO:1902174--P:positive regulation of keratinocyte apoptotic process
GO:0033235--P:positive regulation of protein sumoylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001745	Ailuropoda melanoleuca	95.87	0.00e+00	903.00
IUUC-Apl-003765	Anas platyrhynchos	81.48	0.00e+00	821.00
IUUC-Ame-010763	Astyanax mexicanus	58.74	1.00e-143	502.00
IUUC-Bta-012369	Bos taurus	94.55	0.00e+00	902.00
IUUC-Cja-019450	Callithrix jacchus	91.25	0.00e+00	885.00
IUUC-Cfa-020933	Canis familiaris	94.17	0.00e+00	896.00
IUUC-Cpo-022112	Cavia porcellus	91.56	0.00e+00	847.00
IUUC-Csa-023913	Chlorocebus sabaeus	80.31	0.00e+00	719.00
IUUC-Cgl-026533	Colletotrichum gloeosporioides	27.23	4.00e-34	139.00
IUUC-Dre-027609	Danio rerio	58.45	4.00e-139	488.00
IUUC-Dno-029664	Dasypus novemcinctus	74.75	7.00e-152	530.00
IUUC-Ete-032988	Echinops telfairi	90.85	3.00e-168	584.00
IUUC-Eca-034430	Equus caballus	91.30	0.00e+00	879.00
IUUC-Fca-035968	Felis catus	98.63	6.00e-171	592.00
IUUC-Fal-037449	Ficedula albicollis	82.32	0.00e+00	801.00
IUUC-Fso-038103	Fusarium solani	34.72	7.00e-27	114.00
IUUC-Gmo-038925	Gadus morhua	59.80	2.00e-135	475.00
IUUC-Ggr-039896	Gaeumannomyces graminis	32.05	2.00e-29	123.00
IUUC-Gga-040362	Gallus gallus	83.88	0.00e+00	835.00
IUUC-Gac-042353	Gasterosteus aculeatus	58.22	8.00e-130	457.00
IUUC-Ggo-044810	Gorilla gorilla	90.27	0.00e+00	849.00
IUUC-Hsa-045784	Homo sapiens	92.22	0.00e+00	899.00
IUUC-Itr-048486	Ictidomys tridecemlineatus	90.78	0.00e+00	870.00
IUUC-Lch-049727	Latimeria chalumnae	71.69	1.00e-151	528.00
IUUC-Loc-052354	Lepisosteus oculatus	52.62	3.00e-118	418.00
IUUC-Laf-054261	Loxodonta africana	93.20	0.00e+00	899.00
IUUC-Mcc-054931	Macaca mulatta	91.83	0.00e+00	882.00
IUUC-Meu-056468	Macropus eugenii	86.21	0.00e+00	860.00
IUUC-Mga-059981	Meleagris gallopavo	88.05	0.00e+00	702.00
IUUC-Mvi-060421	Microbotryum violaceum	28.82	4.00e-28	119.00
IUUC-Mmr-061181	Microcebus murinus	89.86	0.00e+00	852.00
IUUC-Mdo-062345	Monodelphis domestica	85.83	0.00e+00	858.00
IUUC-Mmu-063197	Mus musculus	85.63	0.00e+00	824.00
IUUC-Mlu-067194	Myotis lucifugus	93.60	0.00e+00	900.00
IUUC-Ncr-068929	Neurospora crassa	27.70	3.00e-27	116.00
IUUC-Ont-072227	Oreochromis niloticus	58.68	3.00e-136	478.00
IUUC-Ola-086865	Oryzias latipes	58.89	2.00e-133	468.00
IUUC-Oga-088945	Otolemur garnettii	92.22	0.00e+00	897.00
IUUC-Oar-089412	Ovis aries	92.05	0.00e+00	872.00
IUUC-Ptr-091550	Pan troglodytes	85.71	0.00e+00	636.00
IUUC-Pan-092183	Papio anubis	91.63	0.00e+00	896.00
IUUC-Psi-093003	Pelodiscus sinensis	84.42	0.00e+00	830.00
IUUC-Pfo-096704	Poecilia formosa	58.86	1.00e-138	486.00
IUUC-Pab-097923	Pongo abelii	96.06	0.00e+00	753.00
IUUC-Pca-100249	Procavia capensis	78.51	6.00e-143	500.00
IUUC-Pva-102562	Pteropus vampyrus	89.50	0.00e+00	842.00
IUUC-Rno-105762	Rattus norvegicus	86.41	0.00e+00	827.00
IUUC-Sce-106398	Saccharomyces cerevisiae	33.53	3.00e-28	120.00
IUUC-Sha-107253	Sarcophilus harrisii	86.79	0.00e+00	857.00
IUUC-Sja-107662	Schizosaccharomyces japonicus	34.48	2.00e-28	120.00
IUUC-Sar-113149	Sorex araneus	84.70	3.00e-124	438.00
IUUC-Ssc-115241	Sus scrofa	95.33	0.00e+00	908.00
IUUC-Tgu-116884	Taeniopygia guttata	83.07	0.00e+00	798.00
IUUC-Tru-118031	Takifugu rubripes	58.68	3.00e-141	494.00
IUUC-Tni-119766	Tetraodon nigroviridis	58.68	2.00e-136	478.00
IUUC-Ttr-128556	Tursiops truncatus	84.90	0.00e+00	743.00
IUUC-Xtr-131866	Xenopus tropicalis	75.48	0.00e+00	749.00
IUUC-Xma-133963	Xiphophorus maculatus	58.68	3.00e-131	462.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence