iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-049752

Ensembl Protein ID

ENSLACP00000016761.1

UniProt Accession

H3B4E0; H3B4E0_LATCH

Genbank Protein ID

ENSLACP00000016761

Protein Name

Non-specific serine/threonine protein kinase

Genbank Nucleotide ID

AFYH01034978

Gene Name

MARK4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000014767.1	ENSLACT00000016879.1	ENSLACP00000016761.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/UBA	67.70	0.00e+00	946.00	IUUC-Hsa-045897

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

KMAATPLPPV VLKPTHSTLM GSRSEKGSTW SSRSLGARCR NSIASCTDEQ PHIGNYRLLK 60
TIGKGNFAKV KLARHILTGR EVAIKIIDKT QLNPTSLQKL FREVRIMKGL NHPNIVKLFE 120

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Nucleotide Sequence
(Fasta)

AAGATGGCTG CTACCCCCCT TCCCCCCGTT GTTTTAAAAC CCACTGTCAC TTGGGACTAT 60
TTATATTGGC ACAGGACAGC AGAAGAAGGG GATACGAGTT CAAACTGAGA GGAGGAAGAT 120

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Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase

Interpro

IPR028375--KA1/Ssp2_C
IPR001772--KA1_dom
IPR011009--Kinase-like_dom
IPR033624--MARK/par1
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS

PROSITE

PS50032--KA1
PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST

Pfam

PF02149--KA1
PF00069--Pkinase

SMART

SM00220--S_TKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0030010--P:establishment of cell polarity
GO:0000226--P:microtubule cytoskeleton organization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Bta-013546	Bos taurus	68.90	0.00e+00	899.00
IUUC-Cja-019522	Callithrix jacchus	69.08	0.00e+00	920.00
IUUC-Cfa-020231	Canis familiaris	68.36	0.00e+00	893.00
IUUC-Cpo-022532	Cavia porcellus	67.97	0.00e+00	892.00
IUUC-Csa-023700	Chlorocebus sabaeus	65.91	0.00e+00	862.00
IUUC-Cgl-026480	Colletotrichum gloeosporioides	42.16	2.00e-69	257.00
IUUC-Dor-030478	Dipodomys ordii	64.97	0.00e+00	849.00
IUUC-Fca-035898	Felis catus	68.99	0.00e+00	900.00
IUUC-Gmo-039460	Gadus morhua	69.14	0.00e+00	867.00
IUUC-Gac-042324	Gasterosteus aculeatus	68.30	0.00e+00	928.00
IUUC-Ggo-044770	Gorilla gorilla	65.64	0.00e+00	849.00
IUUC-Hsa-045897	Homo sapiens	69.03	0.00e+00	913.00
IUUC-Itr-049080	Ictidomys tridecemlineatus	69.57	0.00e+00	936.00
IUUC-Laf-053534	Loxodonta africana	67.39	0.00e+00	876.00
IUUC-Mcc-054804	Macaca mulatta	68.23	0.00e+00	897.00
IUUC-Meu-056140	Macropus eugenii	69.22	0.00e+00	957.00
IUUC-Mmr-060587	Microcebus murinus	68.46	0.00e+00	906.00
IUUC-Mmu-064289	Mus musculus	70.24	0.00e+00	944.00
IUUC-Mlu-067933	Myotis lucifugus	75.55	0.00e+00	701.00
IUUC-Nle-069719	Nomascus leucogenys	61.47	0.00e+00	698.00
IUUC-Opr-070607	Ochotona princeps	62.87	0.00e+00	817.00
IUUC-Ont-071444	Oreochromis niloticus	69.35	0.00e+00	937.00
IUUC-Ola-086790	Oryzias latipes	62.92	0.00e+00	873.00
IUUC-Oga-088194	Otolemur garnettii	68.23	0.00e+00	898.00
IUUC-Ptr-091413	Pan troglodytes	68.23	0.00e+00	898.00
IUUC-Pab-098074	Pongo abelii	66.76	0.00e+00	860.00
IUUC-Pva-103242	Pteropus vampyrus	66.35	0.00e+00	891.00
IUUC-Rno-105368	Rattus norvegicus	69.17	0.00e+00	927.00
IUUC-Tru-117575	Takifugu rubripes	66.80	0.00e+00	891.00
IUUC-Ttr-129093	Tursiops truncatus	65.64	0.00e+00	852.00
IUUC-Xtr-132367	Xenopus tropicalis	71.75	0.00e+00	756.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence