iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-004160

Ensembl Protein ID

ENSAPLP00000008743.1

UniProt Accession

U3INC0; U3INC0_ANAPL

Genbank Protein ID

ENSAPLP00000008743

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADON01085764

Gene Name

UBR1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000008919.1	ENSAPLT00000009428.1	ENSAPLP00000008743.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/N-recognin/N-domain	1.30e-38	130.7	200	276
E3 activity/RING/RING	9.40e-08	32.2	1077	1181
E3 activity/N-recognin/UBR-box	1.20e-29	102.4	70	140

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/N-recognin/N-domain

   S: 1    YylvLfNDEkHsyeqviyslqkAleleqkeakkfatiidkeGRravkaGdyavceeakkeilknseklaqipLkVev 77
           Yy+vLfNDE+Hsy++viyslq+Al +e+ ea++++t+idkeGRravkaG ya c+eak+ei+++se+++q pL+Vev
   Q: 200  YYCVLFNDEHHSYDHVIYSLQRALGCELSEAQLHTTAIDKEGRRAVKAGRYASCQEAKEEIKRHSENVSQRPLHVEV 276
           9**************************************************************************97 PP

E3 activity/RING/RING

   S: 1    CaiCledf...............kd..............................gplvlpCgHvfhadClqkw............. 29
           C++C+e+                ++                              g+++++CgHv+ha+C+qk+             
   Q: 1077 CILCQEEQevklesaamvlsacvQKstaltqnrsrivelsgdtldplfmhpdlpcGTHTGSCGHVMHATCWQKYfeamqlnfrqrlh 1163
           78885555333333333333333003333333333333333333333333333337999***************************9 PP
   S: 30   .pglknssskefrCPlCr 46
             +  +++++e +CPlC+
   Q: 1164 vEQIFDLENGEYLCPLCK 1181
           99999999*********7 PP

E3 activity/N-recognin/UBR-box

   S: 1    slCgrvfkvgetiyeCrtCsvdetlvlCteCfakvvHkdHeyklkksggggfCdCGdteAwedgskCkkll 71
           +lCg+vfk get+y+Cr+C+vd+t+vlC++Cf++++Hk+H+yk++ s+gggfCdCGdteAw+ g+ C k++
   Q: 70   QLCGKVFKGGETTYSCRDCAVDPTCVLCMDCFQNSIHKNHRYKMHSSTGGGFCDCGDTEAWKAGPVCTKHE 140
           68******************************************************************996 PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

WCDERFDFQA TFLQCLAKHV PNIYSAEMDP LLEKQEEMVQ AAILYPLERY LFGEDPETFL 60
EKLQQSGTSQ LCGKVFKGGE TTYSCRDCAV DPTCVLCMDC FQNSIHKNHR YKMHSSTGGG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGGTGTGATG AAAGATTCGA CTTCCAAGCT ACATTTTTAC AGTGCTTGGC AAAACATGTG 60
CCAAATATTT ACTCAGCTGA GATGGACCCC TTGCTGGAGA AACAAGAAGA AATGGTTCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003769--ClpS_core
IPR014719--Ribosomal_L7/12_C/ClpS-like
IPR011991--WHTH_DNA-bd_dom
IPR013083--Znf_RING/FYVE/PHD
IPR003126--Znf_UBR

PROSITE

PS51157--ZF_UBR

Pfam

PF02617--ClpS
PF02207--zf-UBR

SMART

SM00396--ZnF_UBR1

Gene Ontology

GO:0000502--C:proteasome complex
GO:0000151--C:ubiquitin ligase complex
GO:0070728--F:leucine binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0071233--P:cellular response to leucine
GO:0032007--P:negative regulation of TOR signaling
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001354	Ailuropoda melanoleuca	78.11	0.00e+00	2720.00
IUUC-Aca-004982	Anolis carolinensis	77.85	0.00e+00	2737.00
IUUC-Acl-008055	Aspergillus clavatus	25.47	2.00e-34	142.00
IUUC-Ate-010550	Aspergillus terreus	23.38	6.00e-46	180.00
IUUC-Ame-011231	Astyanax mexicanus	59.17	0.00e+00	1947.00
IUUC-Bgr-011999	Blumeria graminis	23.85	3.00e-51	197.00
IUUC-Bta-012347	Bos taurus	77.91	0.00e+00	2728.00
IUUC-Bci-013834	Botrytis cinerea	23.69	2.00e-50	195.00
IUUC-Cja-018911	Callithrix jacchus	75.36	0.00e+00	2623.00
IUUC-Cfa-020991	Canis familiaris	79.09	0.00e+00	2746.00
IUUC-Cpo-021448	Cavia porcellus	76.98	0.00e+00	2689.00
IUUC-Cre-022930	Chlamydomonas reinhardtii	46.15	3.70e-02	30.00
IUUC-Csa-024255	Chlorocebus sabaeus	78.05	0.00e+00	2228.00
IUUC-Cho-024550	Choloepus hoffmanni	65.53	0.00e+00	1412.00
IUUC-Dno-029427	Dasypus novemcinctus	77.44	0.00e+00	2643.00
IUUC-Dor-031073	Dipodomys ordii	69.13	0.00e+00	1201.00
IUUC-Ete-032318	Echinops telfairi	64.02	0.00e+00	1008.00
IUUC-Eca-033348	Equus caballus	79.15	0.00e+00	2592.00
IUUC-Eeu-034664	Erinaceus europaeus	73.68	0.00e+00	1672.00
IUUC-Fca-035604	Felis catus	73.90	0.00e+00	2522.00
IUUC-Fal-037333	Ficedula albicollis	93.96	0.00e+00	3208.00
IUUC-Fox-037984	Fusarium oxysporum	25.75	1.00e-39	159.00
IUUC-Gmo-039363	Gadus morhua	56.63	0.00e+00	1671.00
IUUC-Gga-040486	Gallus gallus	94.55	0.00e+00	3214.00
IUUC-Gac-041985	Gasterosteus aculeatus	58.42	0.00e+00	1776.00
IUUC-Gma-043622	Glycine max	23.87	3.00e-27	118.00
IUUC-Ggo-044704	Gorilla gorilla	72.37	0.00e+00	2106.00
IUUC-Hsa-046753	Homo sapiens	78.63	0.00e+00	2745.00
IUUC-Itr-048410	Ictidomys tridecemlineatus	78.79	0.00e+00	2718.00
IUUC-Lch-049904	Latimeria chalumnae	63.69	0.00e+00	2155.00
IUUC-Loc-052624	Lepisosteus oculatus	62.97	0.00e+00	2075.00
IUUC-Laf-053857	Loxodonta africana	76.43	0.00e+00	2669.00
IUUC-Mcc-054873	Macaca mulatta	78.57	0.00e+00	2704.00
IUUC-Meu-056858	Macropus eugenii	63.57	0.00e+00	973.00
IUUC-Mpo-057372	Magnaporthe poae	25.05	2.00e-49	191.00
IUUC-Mga-059917	Meleagris gallopavo	94.81	0.00e+00	3320.00
IUUC-Mmr-061128	Microcebus murinus	75.10	0.00e+00	2545.00
IUUC-Mdo-062306	Monodelphis domestica	78.51	0.00e+00	2693.00
IUUC-Mmu-063389	Mus musculus	77.75	0.00e+00	2712.00
IUUC-Mpu-065983	Mustela putorius furo	78.80	0.00e+00	2764.00
IUUC-Mlu-068013	Myotis lucifugus	76.46	0.00e+00	2658.00
IUUC-Nle-070031	Nomascus leucogenys	78.68	0.00e+00	2749.00
IUUC-Opr-070551	Ochotona princeps	60.49	0.00e+00	1238.00
IUUC-Ont-072035	Oreochromis niloticus	58.79	0.00e+00	1992.00
IUUC-Ocu-074930	Oryctolagus cuniculus	75.61	0.00e+00	2591.00
IUUC-Osa-086106	Oryza sativa	42.00	3.00e-12	66.60
IUUC-Ola-086683	Oryzias latipes	58.09	0.00e+00	1933.00
IUUC-Oga-088017	Otolemur garnettii	75.73	0.00e+00	2608.00
IUUC-Oar-089557	Ovis aries	77.41	0.00e+00	2721.00
IUUC-Ptr-091366	Pan troglodytes	77.70	0.00e+00	2719.00
IUUC-Pan-092184	Papio anubis	78.51	0.00e+00	2703.00
IUUC-Psi-093720	Pelodiscus sinensis	85.40	0.00e+00	2885.00
IUUC-Pma-094152	Petromyzon marinus	40.27	1.00e-153	536.00
IUUC-Pfo-097124	Poecilia formosa	59.30	0.00e+00	1976.00
IUUC-Pab-098586	Pongo abelii	78.68	0.00e+00	2744.00
IUUC-Pca-100673	Procavia capensis	68.39	0.00e+00	1529.00
IUUC-Pva-102724	Pteropus vampyrus	73.37	0.00e+00	2496.00
IUUC-Pte-104174	Pyrenophora teres	24.27	8.00e-49	189.00
IUUC-Pyt-104431	Pyrenophora triticirepentis	24.17	2.00e-48	189.00
IUUC-Rno-105474	Rattus norvegicus	74.96	0.00e+00	1964.00
IUUC-Sha-106993	Sarcophilus harrisii	78.05	0.00e+00	2737.00
IUUC-Sar-113447	Sorex araneus	76.04	0.00e+00	1801.00
IUUC-Sre-115045	Sporisorium reilianum	26.74	4.00e-45	177.00
IUUC-Ssc-115768	Sus scrofa	76.03	0.00e+00	2468.00
IUUC-Tgu-116949	Taeniopygia guttata	86.59	0.00e+00	2900.00
IUUC-Tru-117782	Takifugu rubripes	58.00	0.00e+00	1946.00
IUUC-Tsy-119177	Tarsius syrichta	73.05	0.00e+00	1628.00
IUUC-Tni-120884	Tetraodon nigroviridis	54.60	0.00e+00	1772.00
IUUC-Tvi-122272	Trichoderma virens	24.32	9.00e-54	206.00
IUUC-Tae-125358	Triticum aestivum	25.73	2.00e-27	118.00
IUUC-Tbe-128088	Tupaia belangeri	67.53	0.00e+00	1043.00
IUUC-Ttr-129062	Tursiops truncatus	73.61	0.00e+00	2524.00
IUUC-Vpa-130578	Vicugna pacos	71.75	0.00e+00	2413.00
IUUC-Xtr-132244	Xenopus tropicalis	62.42	0.00e+00	2132.00
IUUC-Xma-134112	Xiphophorus maculatus	59.42	0.00e+00	1980.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence