iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSNLEG00000012415.1	ENSNLET00000015866.1	ENSNLEP00000015111.1
ENSNLEG00000012415.1	ENSNLET00000015868.1	ENSNLEP00000015113.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	1.70e-102	343.3	437	775

Active Site

Position(s)	Description	Evidence
743	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldl 90
           ++dlkk+l+v+fvgE+gld+gG+t+e++ ll++++++pd+g+f+y+++++++++ + +      ++ + F+++G+l+g+a++++  ld+
   Q: 437  RADLKKKLKVTFVGEAGLDMGGLTKEWFLLLIRQIFHPDYGMFTYHKDSHCHWFSSFKC-----DNYSEFRLVGILMGLAVYNSITLDI 520
           589***************************************************87766.....789********************** PP
   S: 91   plsksfyklllgk..............klsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipV 165
           ++++++yk+ll+               +++++dl +++pel++ l e++++ e ++ee  +  tf+v +e++g +k+++LkpgG++i+V
   Q: 521  RFPPCCYKKLLSPpiipsdqnipvgicSVTVDDLCQIMPELAHGLSELLSH-EGNVEED-FYSTFQVFQEEFGIIKSYNLKPGGDKISV 607
           *************666666666666555*********************98.6788885.***************************** PP
   S: 166  tneNkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevle 254
           tn+N++eYv+l++++ l+++i +q++af+ Gf++v+  + l l+++ee+e+l+cG++++d+++l++ t+y+g y +++ +i++Fw+v+ 
   Q: 608  TNQNRKEYVQLYTDFLLNKSIYKQFAAFYYGFHSVCASHALMLLRPEEVEILVCGSPDLDMHALQRSTQYDG-YAKTDLTIKYFWDVVL 695
           **********************************************************************76.**************** PP
   S: 255  efsseerkafLqFvTgssrlPlgGfaelkprlfvirk.dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFels 336
           +f  + +k++L+F+Tgs+r+P+gG+a+l+   f i+k ++s++ lP ++TCfn+L+LP+Y+sk+ lk+kL++ i++++gF+l+
   Q: 696  GFPLDLQKKLLHFTTGSDRVPVGGMADLN---FKISKnETSTNCLPVAHTCFNQLCLPPYKSKKDLKQKLIIGISNSEGFGLE 775
           *****************************...9999966777**************************************985 PP

Organism

Nomascus leucogenys

Protein Sequence
(Fasta)

XVPSPATPLV VTAAAPEERK GKESEREKLP PIVSAGAGAT AGLDRGAKGQ ISTFSSFIST 60
VSPKKEAAEN RSSPAHLVFP NIKNVRDQPP ICLDVRQKQR TSMDASSSEM KVPVLPEPIL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

NGGGTACCCT CGCCCGCCAC TCCGCTGGTG GTGACGGCGG CTGCGCCTGA GGAGAGGAAA 60
GGGAAGGAGT CGGAGCGCGA GAAGCTGCCG CCCATCGTAT CGGCGGGCGC CGGCGCGACC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001266	Ailuropoda melanoleuca	95.78	0.00e+00	1471.00
IUUC-Apl-003589	Anas platyrhynchos	84.90	0.00e+00	1287.00
IUUC-Aca-004350	Anolis carolinensis	80.05	0.00e+00	1211.00
IUUC-Ago-007908	Ashbya gossypii	34.46	9.00e-82	298.00
IUUC-Acl-008288	Aspergillus clavatus	34.64	6.00e-96	345.00
IUUC-Afl-008402	Aspergillus flavus	33.28	5.00e-89	322.00
IUUC-Afu-008762	Aspergillus fumigatus	33.61	3.00e-92	333.00
IUUC-Ani-009176	Aspergillus nidulans	34.65	4.00e-91	329.00
IUUC-Ang-009791	Aspergillus niger	34.98	5.00e-91	329.00
IUUC-Aor-009921	Aspergillus oryzae	33.28	4.00e-88	319.00
IUUC-Ate-010295	Aspergillus terreus	34.76	5.00e-98	352.00
IUUC-Ame-010660	Astyanax mexicanus	81.27	4.00e-150	523.00
IUUC-Bgr-011981	Blumeria graminis	31.68	4.00e-93	336.00
IUUC-Bta-012945	Bos taurus	93.28	0.00e+00	1421.00
IUUC-Bci-013697	Botrytis cinerea	38.56	1.00e-79	291.00
IUUC-Cja-019263	Callithrix jacchus	97.31	0.00e+00	1481.00
IUUC-Cfa-020486	Canis familiaris	96.30	0.00e+00	1309.00
IUUC-Cpo-021755	Cavia porcellus	92.90	0.00e+00	1438.00
IUUC-Csa-023814	Chlorocebus sabaeus	98.15	0.00e+00	1410.00
IUUC-Cho-024980	Choloepus hoffmanni	75.97	0.00e+00	1144.00
IUUC-Cgl-026526	Colletotrichum gloeosporioides	41.83	2.00e-98	353.00
IUUC-Dre-028551	Danio rerio	74.44	0.00e+00	1145.00
IUUC-Dno-029497	Dasypus novemcinctus	91.93	0.00e+00	1279.00
IUUC-Dor-030867	Dipodomys ordii	81.58	0.00e+00	1187.00
IUUC-Dse-031239	Dothistroma septosporum	28.87	2.00e-87	318.00
IUUC-Ete-032902	Echinops telfairi	78.36	0.00e+00	1181.00
IUUC-Eca-033678	Equus caballus	94.55	0.00e+00	1426.00
IUUC-Eeu-035262	Erinaceus europaeus	77.10	0.00e+00	1052.00
IUUC-Fca-035590	Felis catus	95.23	0.00e+00	1461.00
IUUC-Fal-037123	Ficedula albicollis	80.37	0.00e+00	1242.00
IUUC-Fox-037941	Fusarium oxysporum	39.08	3.00e-100	360.00
IUUC-Fso-038388	Fusarium solani	39.88	7.00e-103	369.00
IUUC-Gmo-039553	Gadus morhua	65.89	0.00e+00	851.00
IUUC-Ggr-040110	Gaeumannomyces graminis	41.58	2.00e-98	353.00
IUUC-Gga-040406	Gallus gallus	84.27	0.00e+00	1325.00
IUUC-Gac-042141	Gasterosteus aculeatus	75.18	0.00e+00	1108.00
IUUC-Ggo-045504	Gorilla gorilla	98.13	0.00e+00	1510.00
IUUC-Hsa-045786	Homo sapiens	98.13	0.00e+00	1499.00
IUUC-Itr-048050	Ictidomys tridecemlineatus	88.15	0.00e+00	1231.00
IUUC-Kpa-049152	Komagataella pastoris	33.78	1.00e-77	284.00
IUUC-Lch-049824	Latimeria chalumnae	80.12	0.00e+00	1102.00
IUUC-Loc-052173	Lepisosteus oculatus	77.33	0.00e+00	1201.00
IUUC-Laf-054017	Loxodonta africana	93.78	0.00e+00	1340.00
IUUC-Mcc-055713	Macaca mulatta	98.52	0.00e+00	1479.00
IUUC-Meu-056212	Macropus eugenii	68.83	1.00e-114	407.00
IUUC-Mor-057045	Magnaporthe oryzae	38.10	4.00e-91	330.00
IUUC-Mla-059187	Melampsora laricipopulina	43.10	1.00e-87	316.00
IUUC-Mga-059884	Meleagris gallopavo	78.12	0.00e+00	1170.00
IUUC-Mmr-061344	Microcebus murinus	93.32	0.00e+00	1409.00
IUUC-Mdo-062653	Monodelphis domestica	86.59	0.00e+00	1323.00
IUUC-Mmu-063775	Mus musculus	89.05	0.00e+00	1303.00
IUUC-Mpu-066069	Mustela putorius furo	96.10	0.00e+00	1338.00
IUUC-Mlu-067925	Myotis lucifugus	93.60	0.00e+00	1390.00
IUUC-Nfi-068439	Neosartorya fischeri	33.77	8.00e-93	335.00
IUUC-Ncr-068903	Neurospora crassa	36.47	1.00e-92	335.00
IUUC-Opr-071085	Ochotona princeps	79.19	3.00e-137	482.00
IUUC-Ont-072126	Oreochromis niloticus	72.07	0.00e+00	1161.00
IUUC-Oan-072933	Ornithorhynchus anatinus	88.79	0.00e+00	1188.00
IUUC-Ocu-073800	Oryctolagus cuniculus	95.35	0.00e+00	1311.00
IUUC-Ola-086988	Oryzias latipes	75.54	0.00e+00	1113.00
IUUC-Oga-088117	Otolemur garnettii	95.34	0.00e+00	1147.00
IUUC-Oar-089371	Ovis aries	93.19	0.00e+00	1380.00
IUUC-Ptr-090551	Pan troglodytes	97.99	0.00e+00	1455.00
IUUC-Pan-092067	Papio anubis	97.98	0.00e+00	1464.00
IUUC-Psi-092963	Pelodiscus sinensis	84.87	0.00e+00	1275.00
IUUC-Pfo-096562	Poecilia formosa	70.00	0.00e+00	1124.00
IUUC-Pab-098680	Pongo abelii	98.53	0.00e+00	1504.00
IUUC-Pca-100986	Procavia capensis	75.33	0.00e+00	909.00
IUUC-Pva-102219	Pteropus vampyrus	79.40	0.00e+00	1093.00
IUUC-Pgr-103315	Puccinia graminis	35.25	1.00e-94	340.00
IUUC-Ptt-103736	Puccinia triticina	41.28	6.00e-95	342.00
IUUC-Rno-105270	Rattus norvegicus	87.80	0.00e+00	1309.00
IUUC-Sce-106306	Saccharomyces cerevisiae	33.86	4.00e-69	256.00
IUUC-Sha-106819	Sarcophilus harrisii	89.37	0.00e+00	1371.00
IUUC-Spo-108271	Schizosaccharomyces pombe	32.68	2.00e-88	320.00
IUUC-Ssl-108657	Sclerotinia sclerotiorum	30.36	3.00e-83	303.00
IUUC-Sar-113134	Sorex araneus	84.47	0.00e+00	1236.00
IUUC-Ssc-115441	Sus scrofa	94.09	0.00e+00	1399.00
IUUC-Tgu-117166	Taeniopygia guttata	83.00	0.00e+00	1258.00
IUUC-Tsy-118898	Tarsius syrichta	81.95	0.00e+00	1147.00
IUUC-Tre-122108	Trichoderma reesei	37.79	2.00e-89	323.00
IUUC-Tvi-122644	Trichoderma virens	37.90	3.00e-94	340.00
IUUC-Tme-127004	Tuber melanosporum	34.19	2.00e-101	364.00
IUUC-Tbe-127292	Tupaia belangeri	77.79	0.00e+00	1079.00
IUUC-Ttr-128352	Tursiops truncatus	90.60	0.00e+00	1350.00
IUUC-Vda-129969	Verticillium dahliae	40.22	5.00e-95	342.00
IUUC-Vpa-130218	Vicugna pacos	92.08	0.00e+00	1019.00
IUUC-Xtr-132594	Xenopus tropicalis	77.45	0.00e+00	1189.00
IUUC-Xma-134157	Xiphophorus maculatus	74.65	0.00e+00	1043.00
IUUC-Yli-134470	Yarrowia lipolytica	34.14	1.00e-77	285.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence